Darren Yuen/…1
Darren Yuen
124B Finch Avenue West, North York, ON M2N 2H9
Tel: (416)-738-3297 E-mail: darren.yuen@utoronto.ca
EDUCATION & APPOINTMENTS
2011 – present
Canadian Society of Transplantation Postdoctoral Fellowship
Hospital for Sick Children Research Institute, University of Toronto
Supervisor: Dr. Lisa Robinson
2008 – 2011
Doctor of Philosophy
Institute of Medical Science, University of Toronto
Supervisor: Dr. Richard Gilbert
2008 – 2011
Clinician Scientist Training Program
University of Toronto
2008 – 2011
Clinician Investigator Program
Royal College of Physicians and Surgeons of Canada
2006 – 2008
Nephrology Fellowship Program
Faculty of Medicine, University of Toronto
2006 – 2007
Chief Nephrology Resident
Faculty of Medicine, University of Toronto
2005 – 2006
Chief Medical Resident
St. Michael’s Hospital, University of Toronto
2002 – 2006
General Internal Medicine Residency Program
Faculty of Medicine, University of Toronto
1998 - 2002
Doctor of Medicine
Faculty of Medicine, University of Toronto
1995 - 1998
Bachelor of Science (Human Biology)
Faculty of Arts & Science, University of Toronto
MEDICAL LICENCES
Nov 2008 – Present
Nephrology Subspecialty Certification, Royal College of Physicians and Surgeons of
Canada
Nov 2006 – Present
Diplomate in Internal Medicine, American Board of Internal Medicine
July 2006 – Present
College of Physicians and Surgeons of Ontario Independent Practice License
May 2006
Fellow of the Royal College of Physicians and Surgeons of Canada (Internal Medicine)
Darren Yuen/…2
PUBLICATIONS
1)
Petruzziello T, Yuen D, Page A, Patel S, Soltyk A, Matouk C, Wong D, Turgeon P, Fish J, Ho JJD, Steer B,
Khajoee V, Tigdi J, Lee W, Motto D, Advani A, Gilbert RE, Karumanchi SA, Robinson L, Tarr P, Liles WC,
Brunton J, Marsden PA: Functional contribution of the CXCR4/CXCR7/SDF-1 pathway to Shiga toxin-associated
hemolytic uremic syndrome in humans and mice. J Clin Invest 2011 (in press).
2)
Gilbert RE, Zhang Y, Yuen DA: Cell therapy for diabetic nephropathy: is the future, now? Semin Nephrol 2011
(in press).
3)
Yuen DA, Gilbert RE, Marsden PA: New bone marrow cell therapies for endothelial repair and their relevance to
kidney disease. Semin Nephrol 2011 (in press).
4)
Advani A, Connelly KA, Yuen DA, Zhang Y, Advani SL, Trogadis J, Kabir MG, Shachar E, Kuliszewski M,
Leong-Poi H, Stewart DJ, Gilbert RE: Fluorescent microangiography is a novel and widely applicable technique for
delineating the renal microvasculature. PLoS ONE 2011; 6: e24695.
5)
Yuen DA, Kuliszewski MA, Liao C, Rudenko D, Leong-Poi H, Chan CT: Nocturnal home hemodialysis is
associated with restoration of early outgrowth endothelial progenitor-like cell function in end-stage renal disease.
Clin J Am Soc Nephrol 2011; 6: 1345 - 1353.
6)
Gilbert RE, Huang Q, Thai K, Advani SL, Lee K, Yuen DA, Connelly KA, Advani A: EGF-mediated renal
enlargement is attenuated by the histone deacetylase inhibitor vorinostat in experimental diabetes. Kidney Int 2011;
79: 1312- 1321.
7)
Advani A, Huang Q, Thai K, Advani SL, White KE, Kelly DJ, Yuen DA, Connelly KA, Marsden PA, Gilbert RE:
Long-term administration of the histone deacetylase inhibitor, vorinostat, attenuates renal injury in experimental
diabetes through an eNOS-dependent mechanism. Am J Pathol 2011; 178: 2205 – 2214.
8)
Yuen D*, Connelly KA*, Advani A, Liao C, Kuliszewski M, Trogadis J, Thai K, Advani S, Zhang Y, Kelly DJ,
Leong-Poi H, Keating A, Marsden PA, Stewart DJ, Gilbert RE: Culture-modified bone marrow cells attenuate
cardiorenal injury in chronic kidney disease via an antifibrotic mechanism. PLoS ONE 2010; 5(3): e9543.
* Co-first authors
9)
Advani A, Kelly DJ, Cox AJ, White KE, Advani SL, Thai K, Connelly KA, Yuen D, Trogadis J, Herzenberg AM,
Kuliszewski MA, Leong-Poi H, Gilbert RE: The (pro)renin receptor: site-specific and functional linkage to the
vacuolar H+-ATPase. Hypertension 2009; 54: 261 – 269.
10) Connelly K, Yuen D: Optimal blood pressure control in high risk groups: are the guidelines letting us down?
South Med J 2008; 101: 884 – 885.
11) Yuen D, Pierratos A, Richardson RM, Chan CT: The natural history of coronary calcification progression in a
cohort of nocturnal hemodialysis patients. Nephrol Dial Transplant 2006; 21:1407 – 1412.
12) Yuen D, Chan CT: Inflammation, cardiovascular disease and nocturnal hemodialysis. Curr Opin Nephrol
Hypertens 2005; 14: 538 – 542.
13) Yuen D, Richardson RMA, Chan CT: Improvements in phosphate control with short daily in-center
hemodialysis. Clin Nephrol 2005; 64: 364 – 370.
14) Yuen D, Richardson RMA, Fenton SSA, McGrath-Chong ME, Chan CT: Quotidian nocturnal hemodialysis
improves cytokine profile and enhances erythropoietin responsiveness. ASAIO J 2005; 51: 236 – 241.
15) Zhang G, Zhang L, Logan R, Jung BP, Yuen D, Ching Hsu J, Eubanks JH. Decreased expression and impaired
function of muscarinic acetylcholine receptors in the rat hippocampus following transient forebrain ischemia.
Neurobiol Dis 2005; 20: 805- 813.
Darren Yuen/…3
PUBLICATIONS (cont’d)
16) Shen H, Zhang L, Yuen D, Logan R, Jung BP, Zhang G, Eubanks JH: Expression and function of A1
adenosine receptors in the rat hippocampus following transient forebrain ischemia. Neuroscience 2002; 114: 547 –
556.
17) Zhang J, Somani AK, Yuen D, Yang Y, Love PE, Siminovitch KA: Involvement of the SHP-1 tyrosine
phosphatase in regulation of T cell selection. J Immunol 1999; 163: 3012 - 3021.
SUBMITTED MANUSCRIPTS
1)
Zhang Y*, Yuen DA*, Advani A, Thai K, Advani SL, Kepecs D, Connelly KA, Gilbert RE: Early outgrowth bone
marrow cells attenuate renal injury and dysfunction via a novel antioxidant mechanism in a mouse model of type 2
diabetes. Diabetes 2011 (submitted).
* Co-1st authors
2)
Yuen DA*, Zhang Y*, White KE, Stead B, Kabir G, Thai K, Advani SL, Connelly KA, Takano T, Cox AJ, Kelly
DJ, Gibson IW, Takahashi T, Harris RC, Advani A: Altered endothelial-podocyte crosstalk mediates albuminuria in
diabetic eNOS knockout mice. Diabetes 2011 (submitted).
* Co-1st authors
Darren Yuen/…4
RESEARCH GRANTS
2009 – 2012
Canadian Institutes of Health Research Operating Grant
“Microvascular regeneration as a therapeutic strategy in cardio-renal disease”
Co-Applicant, $395,571 (3 year grant)
PI: Dr. Richard Gilbert
2009 – 2010
Physicians’ Services Incorporated Foundation Resident Research Grant
“Effects of conventional and nocturnal hemodialysis on vascular progenitor cell biology”
Physicians’ Services Incorporated Foundation
Principal Investigator, $19,500 (1 year grant)
2009 - 2010
Astellas Research Grant
"Novel antifibrotic therapies for chronic allograft nephropathy"
Astellas
Co-Applicant, $49,630.25 (1 year grant)
PI: Dr. Richard Gilbert
2009 – 2011
Heart and Stroke Foundation of Ontario Grant-in-Aid
“Towards an improved understanding of vascular progenitor cell biology in uremia”
Heart and Stroke Foundation of Ontario
Co-Applicant, $135,874 (2 year grant)
Co-PIs: Dr. Christopher Chan, Dr. Howard Leong-Poi
Darren Yuen/…5
RESEARCH AWARDS
2012 – 2014
CIHR Bisby Fellowship
$165,000 ($55,000 per annum for 3 years) – TOP-RANKED fellowship application
2011 – 2013
Canadian Society of Transplantation Postdoctoral Fellowship
$100,000 ($50,000 per annum for 2 years) – 1st year accepted, 2nd year declined
2011 – 2013
American Society of Transplantation/Pfizer Basic Science Fellowship – DECLINED
$80,000 ($40,000 per annum for 2 years)
2011 – 2012
Heart and Stroke Richard Lewar Centre for Excellence Fellowship – DECLINED
$25,000 for 1 year
2011 – 2012
Edward Christie Stevens Fellowship
2011 – 2012
Joseph M. West Family Memorial Fund
2011
University of Toronto Division of Nephrology Top Trainee Research Abstract
(Basic Science)
2010 – 2012
Starr Medal (awarded 2010 – 2011, 2011 – 2012)
2010 – 2011
Edie Steinberg Scholarship Fund
2010 – 2011
Heidi Sternbach Scholarship
2010 – 2011
Javenthey Soobiah Scholarship
2010 – 2011
William S. Fenwick Fellowship
2010 – 2011
Edward Christie Stevens Fellowship
2010
Banting and Best Diabetes Centre Travel Award
2010
University of Toronto Division of Nephrology Top Trainee Research Abstract
(Basic Science)
2010
AMGEN Young Investigators’ Forum Finalist
2009
CIHR – Institute of Circulatory and Respiratory Heath Top Trainee Presentation
2009
University of Toronto Division of Nephrology Top Trainee Research Abstract
(Basic Science)
2009
Institute of Medical Science – Laidlaw Manuscript Competition Finalist
2009
AMGEN Young Investigators’ Forum 1st Prize ($2500)
Darren Yuen/…6
RESEARCH AWARDS (continued)
2008 – 2011
KRESCENT Postdoctoral Fellowship
Kidney Foundation of Canada & Canadian Institutes of Health Research
$195,000 ($65,000 per annum for 3 years)
2008 – 2011
Kidney Foundation of Canada Postdoctoral Fellowship - DECLINED
Kidney Foundation of Canada
$135,000 ($45,000 per annum for 3 years)
2008 – 2011
Canadian Diabetes Association Postdoctoral Fellowship – DECLINED
Canadian Diabetes Association
$120,000 ($40,000 per annum for 3 years)
2008 – 2009
William S. Fenwick Resident Research Fellowship ($6000)
2008 – 2009
Charles Fell Charitable Trust Resident Research Scholarship ($2800)
Darren Yuen/…7
CLINICAL AWARDS & HONOURS
Nephrology Fellowship, University of Toronto
2007
Goldstein Clinician Award
Awarded in recognition of clinical skills in the Nephrology Fellowship
General Internal Medicine Residency, University of Toronto
2006
Dr. J. Joseph Connon Award
Awarded in recognition of dedication, enthusiasm, and excellence in teaching to both
Undergraduate and Postgraduate Medical students
2006
Fitzgerald Academy Resident Teacher Excellence Award
Awarded in recognition of continued passion, enthusiasm, and excellence in teaching of
undergraduate medical students
2005 – 2006
Chief Medical Resident
St. Michael’s Hospital
2005 & 2003
Murray Muirhead Award
Awarded to a St. Michael’s Hospital resident for superior clinical ability, knowledge, and
excellent interpersonal skills
2004 & 2003
Fitzgerald Academy Teaching Award
Awarded to residents for outstanding teaching at St. Michael’s Hospital
University of Toronto Medical School
2002
Cody Gold Medal
Awarded to the student completing medical school with the highest overall average
2002
Dr. Murray Shafran Scholarship
Awarded for outstanding undergraduate achievement in Internal Medicine
2002
Dr. Gabriel Leung Memorial Award
Awarded for excellence in Family Medicine in fourth year
2002
Mary L. Cassidy Award
Awarded for outstanding contributions to extracurricular activities in the Faculty of Medicine
2002
Dr. Naresh Kumar Award
Awarded based on financial need and demonstrated interest in cardiology
2001
Alpha Omega Alpha Honour Medical Society, Member
Awarded by the Faculty of Medicine to the top four percent of the 2002 class based on highest
aggregate marks in first, second, and third year
1998 - 2001
Honours Standing: Years 1, 2, and 3
2001
Gladwin Ridings Memorial Scholarship
Awarded to a student who has demonstrated high academic standing, modesty,
sensitivity, practicality, and reverence for human life
Darren Yuen/…8
CLINICAL AWARDS & HONOURS (cont’d)
2000
Lidia A. Dykun – Class of 8T1 – Memorial Scholarship
Awarded to a student with high academic standing, a sound character, and who has made
significant contributions in extracurricular activities in the Faculty of Medicine
2000
Charles E. Frosst Medical Scholarship
Awarded for the highest academic standing in second year
1999 – 2001
Dr. C. S. Wainwright Memorial Scholarship
Awarded for academic excellence in first year. Re-awarded in the second and third years for
continued academic excellence
1999
Chinese Canadian Medical Society Scholarship
Awarded for the highest aggregate mark in Anatomy, Neuroanatomy, & Histology
1999
Chamberlain-Heaslip Foundation Undergraduate Research Fellowship
1998
Armando and Nicolina Pavone Outstanding Achievement Award
Darren Yuen/…9
ABSTRACTS – ORAL PRESENTATIONS
1)
Yuen D, Advani A, Zhang Y, Connelly K, Gilbert RE. Progenitor cell secretory products are renoprotective in vitro
and in vivo: efficacy of cell free conditioned medium in the remnant kidney model. American Society of Nephrology,
Denver 2010.
2)
Zhang Y, Yuen D, Thai K, Advani S, Connelly K, Advani A, Gilbert RE. Bone marrow derived endothelial
progenitor cells ameliorate experimental diabetic nephropathy: therapeutic and mechanistic implications. American
Society of Nephrology, Denver 2010.
3)
Yuen D, Advani A, Connelly K, Kepecs D, Thai K, Advani S, Gilbert RE. The effect of diabetes on bone marrow
derived cell function in progressive chronic kidney disease. AMGEN Young Investigators’ Forum, Ottawa 2010.
4)
Yuen D, Connelly K, Advani A, Liao C, Kuliszewski M, Trogadis J, Thai K, Advani S, Zhang Y, Kelly DJ, LeongPoi H, Stewart DJ, Gilbert RE: Bone marrow derived cells attenuate renal and cardiac injury in a model of
progressive CKD via a novel antifibrotic mechanism. American Society of Nephrology, San Diego 2009.
5)
Kuliszewski M, Rudenko D, Connelly KA, Yuen D, Trogadis J, Advani A, Gilbert RE, Leong-Poi H: A novel
technique for assessing the renal microvasculature in chronic kidney disease. American Heart Association Scientific
Sessions, Orlando 2009.
6)
Yuen D, Connelly K, Advani A, Liao C, Kuliszewski M, Trogadis J, Thai K, Advani S, Zhang Y, Kelly DJ, LeongPoi H, Stewart DJ, Gilbert RE: Cultured bone marrow cells attenuate progressive renal injury in a model of chronic
kidney disease. Canadian Society of Nephrology, Edmonton, 2009.
7)
Yuen D, Connelly K, Advani A, Liao C, Kuliszewski M, Trogadis J, Thai K, Advani S, Zhang Y, Kelly DJ, LeongPoi H, Stewart DJ, Gilbert RE: Bone marrow endothelial-like progenitor cell infusion attenuates renal injury in a
model of progressive kidney disease. AMGEN Young Investigators’ Forum, Lake Louise, 2009.
ABSTRACTS – POSTERS
1)
Yuen D, Zhang Y, Advani A, Connelly K, Ladak K, Kepecs D, Advani S, Thai K, Gilbert RE. Diabetes impairs
the in vitro and in vivo activity of progenitor cells in CKD: implications for autologous cell therapy. American Society of
Nephrology, Denver 2010.
2)
Yuen D, Kuliszewski M, Liao C, Rudenko D, Advani S, Thai K, Leong-Poi H, Chan CT. Nocturnal hemodialysis
is associated with improved angiogenicity of endothelial progenitor cells compared with conventional hemodialysis.
American Society of Nephrology, Denver 2010.
3)
Yuen DA, Zhang Y, White KE, Connelly KA, Kelly DJ, Takahashi T, Harris RC, Advani A. Endothelial nitric
oxide synthase deficiency causes an acute podocytopathy in diabetic mice. American Society of Nephrology, Denver 2010.
4)
Yuen D, Advani A, Connelly K, Thai K, Gilbert RE. Cultured bone marrow cells release potent soluble antifibrotic
factor(s) that inhibit intracellular TGF- signalling. Canadian Society of Nephrology, Montreal 2010.
5)
Advani A, Huang Q, Thai K, Advani SL, White KE, Yuen DA, Connelly KA, Marsden PA, Gilbert RE. The
histone deacetylase inhibitor , vorinostat, attenuates oxidative stress and injury in experimental diabetic
nephropathy via eNOS-dependent mechanisms. American Diabetes Association, Orlando 2010.
6)
Advani A, Yuen D, Thai K, Advani SL, Connelly KA, Kepecs D, Sood MM, Gibson IW, Kelly DJ, Gilbert RE:
Decreased stromal cell-derived factor-1 in chronic kidney disease: implications for regeneration of the
microvasculature. American Society of Nephrology, San Diego 2009.
7)
Advani A, Huang Q, Lee K, Thai K, Advani SL, Connelly KA, Yuen D, Gilbert RE: The histone deacetylase
inhibitor vorinostat attenuates early diabetic nephropathy. American Society of Nephrology, San Diego 2009.
Darren Yuen/…10
ABSTRACTS – POSTERS (cont’d)
8)
Kuliszewski M, Rudenko D, Connelly KA, Yuen D, Trogadis J, Gilbert RE, Leong-Poi H: Assessment of
myocardial microvascular abnormalities in chronic kidney disease. American Heart Association Scientific Sessions, Orlando
2009.
9)
Yuen D, Connelly K, Advani A, Liao C, Kuliszewski M, Trogadis J, Thai K, Advani S, Zhang Y, Kelly DJ, LeongPoi H, Stewart DJ, Gilbert RE: Cultured bone marrow cells attenuate cardiac injury and dysfunction in a model of
progressive chronic kidney disease. Basic Cardiovascular Sciences Conference 2009: Molecular Mechanisms of Cardiovascular
Disease, American Heart Association, Las Vegas, 2009.
10) Yuen D, Connelly K, Advani A, Leong-Poi H, Kuliszewski M, Trogadis J, Advani S, Thai K, Kelly DJ, Gilbert RE:
Chronic kidney disease induces cardiac microvascular rarefaction and diastolic dysfunction. American Society of
Nephrology, Philadelphia 2008.
11) Yuen D, Chan CT and Jamal SA: Conventional hemodialysis is associated with greater bone loss than nocturnal; a
prospective study. American Society of Nephrology, San Francisco 2007.
12) Yuen D, Richardson RMA, Fenton SSA, McGrath-Chong M and Chan CT: Quotidian nocturnal hemodialysis
improves cytokine profile and enhances erythropoietin responsiveness. Canadian Society of Nephrology, Calgary 2005.
13) Yuen D, Pierratos A and Chan CT: Nocturnal hemodialysis results in stable coronary calcification as measured by
helical computed tomography in patients with end stage renal disease. American Society of Nephrology, St. Louis 2004.
INVITED PRESENTATIONS
1)
Yuen D. Renal fibrosis: developing new therapies for an old problem. Presented at: Hospital for Sick Children
Transplant Centre Rounds, Toronto 2011.
2)
Yuen D. Novel anti-fibrotic therapies for chronic allograft dysfunction. Presented at: Astellas Toronto Transplant
Symposium, Toronto 2011.
3)
Yuen D. Early outgrowth endothelial progenitor-like cells: a novel therapy for cardio-renal syndrome. Presented at:
University of British Columbia Nephrology Grand Rounds, Vancouver 2011.
4)
Yuen D. Early outgrowth endothelial progenitor-like cells: a novel therapy for cardio-renal syndrome. Presented at: Fraser
Valley Health Nephrology Grand Rounds, Vancouver 2011.
5)
Yuen D. Early outgrowth endothelial progenitor-like cells: a novel therapy for cardio-renal syndrome. Presented at:
University of Calgary Nephrology Grand Rounds, Calgary 2011.
6)
Yuen D. Novel cell-based therapies for cardio-renal syndrome. Presented at: Sunnybrook Health Sciences Centre
Nephrology Grand Rounds, Toronto 2011.
7)
Yuen D. Early outgrowth cells as a novel therapy for diabetic nephropathy. Presented at: St. Michael’s Hospital
Nephrology Grand Rounds, Toronto 2011.
8)
Yuen D. Fibrosis, allograft dysfunction, and endothelial progenitor cells. Presented at: Day in Transplant (Invited
Faculty), University of Toronto, Toronto 2010.
9)
Yuen D. Endothelial progenitor cells: a novel therapy for chronic kidney disease and its vascular complications. Presented at:
University Health Network Nephrology Grand Rounds, Toronto 2010.
10) Yuen D. Endothelial progenitor cells: a novel therapy for chronic kidney disease and its vascular complications. Presented at
Latner Thoracic Surgery Research Rounds, Toronto 2010.
Darren Yuen/…11
INVITED PRESENTATIONS (cont’d)
11) Yuen D. Endothelial progenitor cells: a novel therapy for chronic kidney disease and its vascular complications. Presented at:
McGill University Nephrology Grand Rounds, Montreal 2010.
12) Yuen D. Endothelial progenitor cells: a novel renoprotective therapy for chronic kidney disease. Presented at: University of
Ottawa Nephrology Grand Rounds, Ottawa 2010.
13) Yuen D. Endothelial progenitor cells: a novel renoprotective therapy for cardio-renal syndrome. Presented at: University of
Alberta Nephrology Grand Rounds, Edmonton 2010.
14) Yuen D. Endothelial progenitor cells: a novel renoprotective therapy for diabetic kidney disease. Presented at: University of
Alberta Nephrology Research Seminar, Edmonton 2010.
15) Yuen D. Endothelial progenitor cells: a novel renoprotective therapy. Presented at: St. Michael’s Hospital Nephrology
Grand Rounds, Toronto 2010.
16) Yuen D. Exploring the role of endothelial progenitor cells for the treatment of diabetic kidney disease. Presented at: Banting
and Best Diabetes Centre Rounds, University of Toronto, Toronto 2010.
17) Yuen D. Cultured bone marrow cells: A novel therapy for cardio-renal syndrome. Presented at: Citywide Nephrology
Rounds, University of Toronto, Toronto 2010.
18) Yuen D. Bone marrow cells and fibrovascular complications in chronic kidney disease. Presented at: Vascular Access
Symposium, Toronto 2010.
19) Yuen D. Bone marrow cell therapy for the cardiac and renal manifestations of chronic kidney disease. Presented at: St.
Michael’s Hospital Cardiology Research Rounds, Toronto 2009.
20) Yuen D. Bone marrow cell therapy for cardiorenal syndrome. Presented at: St. Michael’s Hospital Research Semianr
Series, Toronto 2009.
21) Yuen D. Bone marrow cell therapy for cardiac and renal injury in chronic kidney disease. Presented at: Ottawa Health
Research Institute Vascular Seminar Series, Ottawa 2009.
22) Yuen D. KRESCENT: Supporting the training of a renal clinician scientist. Presented at: Canadian Society of
Nephrology Satellite Symposium, Edmonton 2009.
23) Yuen D. Endothelial-like progenitor cells attenuate renal and cardiac injury in a model of progressive chronic kidney disease .
Presented at: University Health Network Division of Nephrology Rounds, University of Toronto 2009.
24) Yuen D. Endothelial-like progenitor cells attenuate renal and cardiac injury in a model of progressive chronic kidney disease .
Presented at: St. Michael’s Hospital Division of Nephrology Rounds, University of Toronto 2009.
25) Yuen D. Nocturnal Hemodialysis and Cardiovascular Physiology. Presented at: Dr. Cecilia Giachelli Lab Research
Rounds, University of Washington 2007.
26) Yuen D. Nocturnal Hemodialysis and Its Effects on the Cardiovascular System. Presented at: Division of Nephrology
Grand Rounds, University of Ottawa 2007.
27) Yuen D. Nocturnal Hemodialysis and Vascular Disease in Uremia. Presented at: Division of Nephrology Grand
Rounds, University of Nottingham 2007.
Darren Yuen/…12
REVIEWER FOR JOURNALS
1)
Biology of Blood and Bone Marrow Transplantation
CONFERENCE ORGANIZATION
1)
Panel discussant: Clinical Molecular Conference, Canadian Society of Nephrology, Montreal, May 2010.
2)
Co-Chair: Applied Basic Science Session, Vascular Access Symposium, Toronto, April 2010.
PATENTS
1)
Antifibrotic compositions (provisional). Filed February 2010.
PRESS COVERAGE
1)
CTV news interview: “Nocturnal hemodialysis”. June 29, 2011
Darren Yuen/…13
LEADERSHIP AND COMMITTEE POSITIONS
2007 – Present
Executive Division of Nephrology Committee, University of Toronto
2006 – 2007
Chief Nephrology Resident, University of Toronto
2006 – 2007
Postgraduate Nephrology Education Committee, University of Toronto
2005 – 2006
Chief Medical Resident, St. Michael’s Hospital, University of Toronto
2005 – 2006
Medical Grand Rounds Committee, St. Michael’s Hospital, University of Toronto
2005 – 2006
Internal Medicine Core Committee, St. Michael’s Hospital, University of Toronto
2005 – 2006
Cardiac Arrest Committee, St. Michael’s Hospital, University of Toronto
2005 – 2006
Ambulatory Internal Medicine Group Practice Clinic Restructuring Committee, St.
Michael’s Hospital, University of Toronto
2005 – 2006
Computerized Provider Order Entry Committee, St. Michael’s Hospital, University of
Toronto
2003 – 2004
PGY-2 Representative, Internal Medicine Core Committee, University of Toronto
2003 – 2004
PGY-2 Representative, Residency Training Committee, University Health Network
2001 – 2002
4th Year Student Representative, Internal Medicine Clerkship Committee
2000 - 2001
3rd Year Student Representative, Internal Medicine Clerkship Committee
2000 - 2002
Awards Committee Representative, Faculty of Medicine, University of Toronto
2000 - 2002
Student Representative, Ambulatory Community Experience Committee
1999 - 2000
Second Year Class Co-President, Faculty of Medicine, University of Toronto
MEDICAL SOCIETY MEMBERSHIPS
Canadian Society of Nephrology
International Society of Nephrology
American Society of Nephrology
Canadian Society of Transplantation
Ontario Medical Association
Canadian Medical Association
Royal College of Physicians and Surgeons of Canada