Proposed Course requirements for the Ph.D. Degree in Pathology & Microbiology, Specialty Track in Bioinformatics Admission Requirements Students must meet the existing admission requirements as defined by the Pathology and Microbiology Department of UNMC. For admission to the departmental graduate program, the applicant must have at least a Bachelor's degree in Science with a broad background in the sciences that include courses in organic and quantitative chemistry, biochemistry, calculus, and physics. The applicant must present both an academic record and background that are acceptable to the departmental Graduate Committee. All successful applicants for the PhD degree should have at least a 'B' average in college coursework and will be required to take the Graduate Record General Exam (GRE); Successful applicants will be expected to score above the 40th percentile in each of the three (verbal, quantitative, analytical) general exam areas. Applicants who are deficient in one or two of the course requirements for admission, but who are otherwise well qualified, may be admitted on the provision that deficiencies are removed prior to admission to candidacy. All application materials required by the Graduate Studies Office at the University of Nebraska Medical Center must be supplied before action can be taken on a candidate's application. Written letters of recommendation, as well as personal motivation as judged by the student's own personal statement, significantly influence the evaluation of the potential of the applicant to complete a rigorous course of advanced and original studies in a field of modern biology. If it is considered appropriate and necessary to the evaluative process, the applicant will be invited for an interview with members of the Departmental Graduate Committee. Program of Study TThe Graduate Committee of the Pathology & Microbiology Department at UNMC will oversee and be responsible for advising and training of students. Students in the BioInformatics specialty track must satisfy the graduate requirements of the UNMC Graduate Studies program and the Department of Pathology and Microbiology. Introductory/Foundation Courses The following introductory or foundation courses are recommended to facilitate entry and progress through the BioInformatics specialty track. The number of courses will vary from student to student. For example, a student with a strong biology/chemistry background would ignore the foundation biology and chemistry courses and focus of the information and computer science courses. The reverse would be true for students with a background in information and computer science. Undergraduate Biology and Chemistry BIOL 2140 Genetics, 3020 Molecular Biology of the Cell and CHEM 2210 Fundamentals of Organic Chemistry or CHEM 2250, 2260, 2274 Organic Chemistry I/II and Lab or equivalents Introduction to Bioinformatics Seminar course Computer Science CIST 1400 - Introduction to Computer Programming CIST 1404 - Introduction to Computer Programming Lab CSCI 1620 - Introduction to Computer Science II Information Systems & Quantitative Analysis CIST 2110 - Organizations, Applications and Technology ISQA 2010 - Statistics for Information Systems (or equivalent) ISQA 8040 - An Overview of Systems Development ISQA 8050 - Data Organization and Storage Core Courses All students are required to take the core course requirements for the Graduate Degree in Pathology & Microbiology. The Core course requirements for Pathology and Microbiology Ph.D. degree: BIOC 841-842 - Molecular and Cell Biology UNMC, or equivalent PAMM 857 - Medical Immunology UNMC, or equivalent The BioInformatics specialty track has the following additional course requirements: Pathology & Microbiology PAMM 973 - Introduction to Genetic Sequence Analysis PAMM 950 - Special Topics - BioMolecular Informatics UNMC Computer Science CSCI 3320/8325 - Data Structures and algorithms CSCI 4850/8856 - Database management Systems CSCI 4450/8456 - Artificial Intelligence Information Systems & Quantitative Analysis ISQA 4730/8736 - Decision Support Systems ISQA 4880 - Systems Simulation and Modeling Elective Courses In addition to the recommended Foundation courses and required Core courses, students must choose at least two (2) upper level advanced graduate courses, from the folowing list of courses with approval of the Graduate Committee. These electives are to be based on the background and research interests of the student. Biology and Chemistry BIOC 926 - Advanced Topics in Biochemistry Nucleic Acids UNMC P-SM 806-808 - Biostatistics UNMC PAMM 890 - Molecular Biology of Viruses UNMC PAMM 955 - Advanced Immunology UNMC BIOL 8060 - Comparative Genomics UNO Computer Science CSCI 8080 - Design and Analysis of Algorithms CSCI 8070 - Genetic Algorithms CSCI 8156 - Graph Theory and Applications CSCI 8446 Introduction to Parallel Computing Information Systems & Quantitative Analysis ISQA 8210 - Software Project Management ISQA 8220 - Systems Analysis and Design ISQA 8700 - Date Warehousing: Theory and Practice Ph.D. Comprehensive Exam A comprehensive exam will be administered as defined by the Pathology & Microbiology Graduate Committee. This exam is usually taken at 2 1/2 years following entry into the program and includes a research grant application. Thesis Research Research projects will be addressed in consultation of a graduate advisor and the student’s graduate supervisory committee.