Alliance of Centers and Core Facilities for Research and Outreach ECONOMIC DEVELOPMENT CENTER ESTABLISHED – 1981 DIRECTOR: MS. ELLA NUNN PHONE: 713-313-7785 GOALS: To foster economic growth and development throughout the Houston-Galveston area by developing viable and effective community and economic development projects that provide sources and resources, technical assistance and training to the small business sector, Houston’s inner-community organizations, and other undeveloped sectors of the community such as the unemployed, underemployed, and the homeless. PROJECTS: Projects primarily emphasize and promote entrepreneurship, higher education, personal/career development, neighborhood revitalization, technology and community involvement. The current projects are (1) Skills-Training in Automatized Technology and Small Business Technical Assistance which provides workshops and technical assistance for new and existing businesses; assessment of black businesses’ years of operation that are located within third ward, one of the targeted areas; computer skills with job readiness training; GED/college preparation/intern positions; and funding for 2 HUD public housing technology centers. The partnerships and collaborations in this project are Neighborhood Network, Incorporated, Houston Community College System, and Jesse H. Jones School of Business MBA Group of Texas Southern University; and (2) Homeownership Opportunities and Computerized Technology with Technical Assistance to provide economic development to program participants located in the HoustonGalveston area on financial literacy education and preparation for homeownership; funding for creating and equipping a computer technology center to be located within a housing center for senior citizens; workshops on business planning and financial management; grant assistance for revitalization of up to eight (8) minority businesses within the third ward area; career development in computer technology and office administration; and GED/college preparation. The partnerships and collaborations included in this project are TSU/EDC faculty team, William A. Lawson Institute of Peace and Prosperity, Houston Community College System and Womack Development & Investment Realtors, Incorporated. Both projects are funded by the U. S. Department of Housing and Urban Development. GERALD B. SMITH CENTER FOR ENTREPRENEURSHIP & EXECUTIVE DEVELOPMENT ESTABLISHED – 1998 DIRECTOR: TBA PHONE 713-313-7977 GOALS: The mission of the Gerald B. Smith Center for Entrepreneurship and Executive Development is to encourage entrepreneurial thinking and action among students and faculty, to nurture students and faculty to discover and develop new technological products and services, to create new organizations to commercialize these products and services. PROJECTS: Community Outreach Initiatives: Developing alliances with other university centers as well as local area Citizen’s Chambers of Commerce, the Small Business Administration (SBA), SCORE “Counselors to America’s Small Business”, and various Economic Development Center. Student Led Initiatives: Sponsor of a Business Plan competition for business majors who compete for cash prizes and the opportunity to participate in competitions at a national level. Developed an Entrepreneurs Club was started Spring 2005 for all students. Members learn what it takes to start a business, experience entrepreneurship through club projects, network with students and professionals involved in entrepreneurship, participate in field visits, learn from guest speakers, enter business plan competitions, participate in mentoring and shadowing programs with established entrepreneurs, and participate in social, community, and university events. Houston Technology Center Technology Partnership: Texas Southern University’s partnership with the Houston Technology Center facilitates learning for TSU students through education and exposure to companies involved in the areas of energy, information technology, life sciences, nanotechnology and NASA. Entrepreneurial Lecture Series: Successful entrepreneurs and business professionals discuss subjects significant to entrepreneurs. These entrepreneurs discuss the challenges and rewards of entrepreneurship and give students advice on getting started, becoming successful and developing the business. Council for Entrepreneurship: The Entrepreneurs Council serves as a resource for the students in the area of entrepreneurship. Council members mentor students, provide networking opportunities and assist in the development of entrepreneurial. JPMORGAN CHASE CENTER FOR FINANCIAL EDUCATION ESTABLISHED – 2003 DIRECTOR: GERMAINE GRAY PHONE: 713-313-6877 GOALS: To promote lifelong financial education through teaching, research and community outreach programs and to contribute to an individual’s knowledge of personal finances, money management, credit awareness and estate planning. PROJECTS: Financial education module in freshman level business course. Seminars to raise awareness of JHJ students on personal financial management are conducted each semester. Teacher train-the-trainer workshops emphasizing personal financial management and economic education are held throughout the academic year. INSTITUTE FOR INTERNATIONAL AND IMMIGRATION LAW (IIIL) ESTABLISHED: 2002 DIRECTORS: CRAIG L. JACKSON AND FERNANDO COLON-NAVARRO PHONE: 713-313-1918 GOALS: The Institute (IIIL) is dedicated to providing specialized academic and practical legal training for students planning a career in international or immigration law. The Institute is dedicated to encouraging scholarly research in the fields of international law and immigration law; therefore, IIIL prepares students for positions with law firms practicing international or immigration law; U.S. government agencies, foreign governments, private organizations, and foundations working to advance social and economic justice. The IIIL also provides a scholarly atmosphere for the study of international and immigration law as well as a forum to discuss problems facing those disciplines. The IIIL offers an extensive inventory of international law courses, including but not limited to: International Litigation, International Tax, International Human Rights, Comparative Law, International Law, Employment-Based Immigration, Criminal Law and Immigration, NAFTA, Family-Based Immigration, Basic Mexican Business Law, Naturalization and Citizenship, Treaty Law as well as a Civil Externship Clinic at the Consulate of Mexico, an Administrative Law Clinic: Immigration Law Concentration, and the American and Caribbean Law Initiative, which is a Consortium dedicated to study comparative law issues. The Institute also recognizes students who have demonstrated a deep interest and scholastic achievement in the areas of international law or immigration law through its Certificate Program in International and Immigration Law. PROJECTS: Among the many scholarly programs of the Institute is the Genocide Prosecution Project. Under this project, the Institute is planning to sponsor two programs involving the ad hoc tribunals hearing criminal cases on episodes of genocide in the former Yugoslavia and Rwanda. The International Criminal Tribunal for the former Yugoslavia Program, pending ABA approval, is scheduled to start in the summer of 2006. Tentative plans the International Criminal Tribunal for Rwanda program are being made with that program possibly starting in the summer of 2007. Both programs will involve classroom study of international criminal law, the cases from each tribunal, and the procedures for bringing cases to the tribunals. Students will attend tribunal hearings in The Hague, Netherlands (where the Yugoslavia Tribunal meets) and Arusha, Tanzania (where the Rwanda Tribunal meets). 2 CENTER ON LEGAL PEDAGOGY DIRECTORS: DONALD K. HILL AND DANNYE HOLLEY ESTABLISHED – 1998 PHONE: 713-313-7392 OR 713-313-7388 GOALS: The law school has historically participated in various teaching and learning processes that enhance legal education for students from diverse socioeconomic and cultural backgrounds. The Center operates on the presumption that, while the LSAT/GPA is a valid and genuine indicator of probable success in law school studies, the indexes that are generated, are not indicators of intelligence, but are instead indicators of a potential student's difficulties with analytical skills, and those skills are teachable. The Center has developed a series of initiatives and educational programs to enhance the law school’s curriculum and instruction, including pre-law programs (LEAP and Prep-for-Law), academic support programs, educational workshops, and collaborative teaching and instructional projects with faculty members who teach courses in first year (Property) and in second year (Criminal Procedure and Evidence) as well as with faculty members who teach upper-level topical seminars (Jurisprudence). In addition to providing educational support to deliver mentoring and advising programs to students, the Center has also implemented faculty development forums to enable faculty members to share and impart teaching innovations, to encourage research, and to foster scholarship. PROJECTS: The primary research aim of the Center is to investigate fundamental questions about how legal knowledge is organized and how the cognitive processes that accompany legal knowledge develop with learning and experience. CENTER FOR MINORITY TRAINING AND CAPACITY BUILDING FOR DISABILITY RESEARCH DR. IRVINE E. EPPS - DIRECTOR ESTABLISHED – 2003 PHONE: 713-313-7224 GOALS: The Center’s overall objective is to bridge gaps in disability research and to use evidence based research to address the unmet needs of minorities with disabilities. The Center for Minority Training and Capacity Building for Disability Research and Baylor College of Medicine (BCM) Chronic Disease Prevention and Control Research Center propose the development, implementation, and evaluation of a strong minority/majority institutional collaboration to address training and research development for minorities interested in Vocational Rehabilitation (VR) and disability research related to racial disparities. More specifically, the project develops an innovative research infrastructure of institutional “cores” that partner a Historically Black College and University (HBCU), TSU, with a majority research institution, BCM. The cores include: 1) the Administrative, Planning and Evaluation Core, 2) the Training Core, 3) the Community Collaboration and Dissemination Core and 4) the Research Core. Together, the partner institutions create a collaborative research infrastructure that increase research capacity and help build an institutional research infrastructure at five additional HBCUs in Texas. The Minority Scholars/Champions Research Training Project develops, implements, and evaluates the effectiveness of a train-the-trainer “Scholar/Champion” model to facilitate increased and improved VR/disability research among the targeted HBCUs. The Research Training Project gives promising minority junior investigators at participating institutions the capacity to sustain VR/disability research careers. The project builds upon the strengths and assets of both TSU and BCM in the development of a “best practices” model that can be disseminated to other research institutions to increase minority participation in VR/disability research. PROJECTS: The center partners with communities and VR/disability agencies to engage individuals with disabilities in research and training, using a model of Participatory Action-Oriented Research, and disseminate culturallysensitive information related to VR/disability research to community groups and agencies. The center works with the HBCU Scholar/Champions to conduct innovative and rigorous pilot research projects as well as write fully developed research proposals that address racial disparities in VR/disability research. 3 UNIVERSITY COUNSELING CENTER ESTABLISHED: 2005 DIRECTOR: MRS. HOLLY LEE-LIPKINS, MA, LPC, LCCA PHONE 713-313-1113 GOALS: To be of significant value to the TSU community and to be nationally recognized as a leader among Counseling Centers, providing helping resources of the highest quality to enhance students' progress toward the fulfillment of their personal development and the completion of their education. We strive to expand our roles as helping professionals by being proactive and responsive to the changing needs of the growing and diversifying student population, and to continue developing our services and training programs which meet standards of excellence in our profession. PROJECTS: The University Counseling Center seeks to provide crisis intervention, brief counseling, outreach, and referral services to TSU University students. We also offer consultation, education, training, and prevention strategies to faculty, staff, and the University community. An affiliate of the Counseling Center is the Alcohol and Other Drug Prevention and Education Program. The Program serves as the primary campus office concerning education, personal assistance, and information related to alcohol and other drugs. Staff is involved in promoting and educating for low risk, healthy choices through campus outreach programs, classroom lectures, and computerized programs. For qualified individuals, Services for Students with Disabilities offers specialized services to meet those specific needs that are often required by students with disabilities, provides reasonable accommodations to meet those needs of each student, and eases the matriculation process through TSU. Additionally, the University Counseling Center is a practicum/internship site for selected individuals who choose to extend their professional learning experience to an applied setting. MICKEY LELAND CENTER ON WORLD HUNGER AND PEACE ESTABLISHED – 1989 ASSOCIATE DIRECTOR: MR. JEW DON BONEY PHONE: 713-313-7370 GOALS: To provide on going opportunities for dialogue, projects, programs and research by students and faculty that increase awareness and understanding, leading to innovative projects and programs that address the enduring critical problems of world hunger and peace; and to offer advanced leadership development training to TSU students to prepare them to learn and lead in while providing a means to outreach to today’s diverse global community. PROJECTS: Co-Sponsorship of Annual Intercultural Conference with the School of Communications and Annual Summit on Public Policy and local, state and federal legislation in collaboration with the Earl Carl Institute (TMSL), Development of International Study Abroad Programs for TSU students (MLIEP). Through the Mickey Leland Congressional Internship Program (MLCIP) and the Texas Legislative Internship Program (TLIP) the Leland Center provides undergraduate and graduate students intensive training and unique, exposure as staff members to local, state and national government and elected officials, to increase the number of graduates prepared and available to work in government and public service. CENTER ON THE FAMILY ESTABLISHED – 1990 INTERIM DIRECTOR: DR. NAN DELAFOSSE PHONE: 713-313-7870 GOALS: PROJECTS: To offer opportunities for advancing and implementing multi- and interdisciplinary studies and research on family life issues and to become the University’s vehicle for building public support and advocacy through direct service provisions and comprehensive planning for crisis intervention. Research and service efforts focus on life challenges of children, youth, and the elderly. 4 THE MINNIE T. METTERS WRITING CLINIC ESTABLISHED – 1986 DIRECTOR: LANA REESE PHONE: 713-313-7981 GOALS: The Writing Clinic, provides Computer-Assisted Instruction (CAI) and Traditional Instruction (TI) in writing skills— sentence structure, grammar, usage, mechanics, and basic organization and development of compositions. The Clinic’s primary objective is to assist students in becoming responsible writers who can organize and correct their own errors and apply composition principles and concepts to their writing assignments. The Clinic is developing a databank of information on student performance. The Writing Clinic is NOT a proofreading, editing, correcting, quickfix service and does not assist in preparation of specific class assignments on which the student will receive grades. When students have questions or concerns about specific class assignments, they are encouraged to arrange a conference with their classroom instructors. Students can call the Grammar Hotline (713-313-7981), if they have a question concerning grammar and composition. In addition to CAI and TI, students may view videos or CDs or listen to audio cassettes on both composition and literature. PROJECTS: Measuring Student Progress in Compositional Essay Writing and Web-based learning. INNOVATIVE TRANSPORTATION RESEARCH INSTITUTE EST., 2000 DIRECTOR: DR. LEI YU PHONE: 713-313-7282 GOALS: The Innovative Transportation Research Institute (ITRI) at Texas Southern University was developed in the fall of 2006 by expanding the former Urban Traffic and Air Quality Lab (UTAQL), which was first established in 2000 and has already achieved extensive accomplishments. By utilizing advanced technologies, large scale computer simulation methods, complex modeling systems, and state-of-the-art lab equipments, ITRI attempts to develop, evaluate, optimize, and recommend comprehensive strategies for traffic congestion mitigation, urban transportation planning, ITS development, mobile source emission reduction, and fuel consumption saving. ITRI conducts research through five designated research centers: Center for Modeling and Simulation (CMS), Center for Air Quality Analysis (CAQA), Center for ITS (CITS), Center for Driver Behavior (CDB), and Center for Training and Technology Transfer (CT3). ITRI has developed state-of-the-art lab facilities including: mobile traffic van, fullmotion driving simulator, real-time traffic surveillance system through Houston TranStar, portable emission measurement systems, and a variety of other equipment. PROJECTS: ITRI and its predecessor UTAQL have conducted projects for Federal Highway Administration (FHWA), National Institute of Standards and Technologies (NIST), Air Force Research Laboratory (AFRL), Texas Department of Transportation (TxDOT), Houston Advanced Research Center (HARC), Southwest Region University Transportation Center (SWUTC), etc. Examples of completed projects include: Development of Left-Turn Operations Guidelines at Signalized Intersections (TxDOT), Symbols and Warrants for Major Traffic Generator Guide Signing (TxDOT), Vehicle Infrastructure Integration (VII) Based Road-Condition Warning System For Highway Collision Prevention (SWUTC), Computer Simulation-Based Algorithm For Optimizing Evacuation Plans In Major Trip Generator (SWUTC), Left-Turn Lane Design and Operation (TxDOT), Using GPS and ITS Data to Calibrate the Micro Simulation Model VISSIM (SWUTC), ITS Data Compression by Using Advanced Signal Processing Techniques (SWUTC), Collection and Evaluation of On-Road Vehicle Emission Data and Activity Data (HARC), Measurement and Evaluation of On-Road Vehicle Emissions at Signalized Intersections (SWUTC), How do Changes in Goods Movements Impact Disadvantaged Population (FHWA), Evaluation of Highway Safety Improvement Projects (FHWA), Probability Generation of Frequency and Severity of Nonrecurring Congestion due to Accidents to Improve Emissions Analysis (TxDOT), Evaluation and Combined Use of TRANSYT-7F and CORSIM in Traffic Signal Optimization and Simulation (SWUTC), Synthesis Report on Changeable Message Signs that Depict Symbols and Words (FHWA), Pavement Smoothness Strategies (FHWA), Yellow and Red Intervals to Improve Signal Timing Plans for Left-Turn Movement (TxDOT), Airport-Related Traffic and Mobile Emission Implications (TxDOT), Using Real-Time Traffic Data for Transportation Planning (TxDOT), Forecasting Traffic Characteristics for Air Quality Analyses (TxDOT ), Electronic Energy Storage and Future Transportation (NIST), Using ITS Technology to Improve Highway-Rail Crossing Safety (FHWA), Transportation Expertise Pool (FHWA), Collection and Evaluation of Modal Traffic Data for Determination of On-Road Vehicle Emission Rates 5 Under Certain Driving Conditions (TxDOT and FHWA), Evaluation of Traffic Simulation Models for Supporting ITS Development (SWUTC). CENTER FOR TRANSPORTATION TRAINING AND RESEARCH ESTABLISHED – 1983 DIRECTOR: DR. CAROL LEWIS PHONE: 713-313-1925 GOALS: To provide an interdisciplinary cadre of professionals that serve as a focal point to advance the transportation industry and its functioning in urban and rural environments that add to the body of knowledge through research, by providing an experiential laboratory for students and by facilitating critical dialog about transportation issues. PROJECTS: Active projects in air quality, transit oriented development, noise compatible land use planning, transportation policy, intelligent transportation systems, freight and logistics, emergency evacuation and security and sustainable transportation initiatives as well as research by graduate students, resulting in state-of-the-art knowledge and projects at the forefront of the transportation field. CTTR annually hosts the Houston National Summer Transportation Institute for secondary students to expose them to transportation as a viable career option. Included in CTTR’s programs, is the 3D Traffic Simulation Demonstration Lab which provides 3-dimensional traffic simulation demonstrations and workshops for transportation graduate students and in-service professionals. CTTR is a member of the Southwest Region University Transportation Center – a consortium with Texas A&M University and the University of Texas and is a regional partner with the Texas Transportation Institute. ENVIRONMENTAL RESEARCH AND TECHNOLOGY TRANSFER CENTER EST., 1991 DIRECTOR: DR. BOBBY WILSON PHONE: 713-313-4259 GOALS: To address training, research problems, and technology transfer issues as they relate to the environment; by increasing the number of under-represented minority graduates in science, mathematics, engineering, and technology. PROJECTS: ERT2C projects focus on analysis of toxic elements and compounds in a closed environment, trace metals in soil, soil sediments, air and wastewater processes, wastewater contaminants, and environmental policy and law. The Core Analytical Facility is an important component of the center. The Core’s mission is to achieve regional, community, and national recognition as a quality environmental analytical laboratory and environmental research program. This Mission will be achieved through the characterization of environmental toxicants in the ambient environment (air, soil, and/or water) and the investigation of the mechanisms involved in the toxicity effect. The facility is equipped with Chromatographic Equipment: Gas Chromatography: 2 -Agilent 6890 Gas Chromatographs with 5973 MS; GC accessories: Entech 7100 Preconcentrator for air monitoring with 32 6L Silonite Canisters, Tekmar Doarman- Velocity XPT Purge and Trap. Liquid Chromatographs: Dionex DX-600 Ion Chromatograph, Agilent 1100 High Performance Liquid Chromatograph w/ (MS). Spectrophotometric Equipment: Agilent 7500 Inductively Coupled Plasma w/ Mass Spectrometry (MS), Thermo Electron Nexus 470 FTIR with a 10-meter gas cell, Graphite Furnace Atomic Absorption Spectrometer: Perkin Elmer. Miscellaneous Equipment: Glove Box, Dionex Accelerated Extraction System. The following projects are ongoing: 1. Identification and Quantification of Volatile Organic Compounds (VOCs) in the Urban Atmosphere of Houston, Texas 2. Public Drinking Water Study in the Greater Houston Area 3. Assessment of Aquatic Environmental Estrogens in the Lower Galveston Bay Watershed 4. Study of Oxidative Stress Biomarkers caused by Space Travel 6 NASA UNIVERSITY RESEARCH FOR BIOTECHNOLOGY AND ENVIRONMENTALHEALTH EST., 2003 DIRECTOR: DR. OLUFISAYO JEJELOWO PHONE 713-313- 7841 Goals: The NASA URC goals and objectives focus on research and technology development and demonstration for ensuring the health, habitation, safety and effectiveness of crews in and beyond low Earth orbit. The URC genotoxicology group supports life science areas that will enable human space exploration by: (1) expanding biomedical knowledge and developing tools to reduce the uncertainty of estimation of space radiation health risks to human crews of acute and life-long carcinogenesis, brain and other tissue non-cancer damage, and (2) providing new information in exploration biology, which will identify and define the scope of problems which will face future human space explorers during long periods of exposure to space. The URC microorganism group enables human exploration beyond low Earth orbit by (1) achieving a new level of reliable and maintainable life support and environmental monitoring and control systems. Emphasis will be to enhance reliability, maintainability, portability, and system distribution, and (2) ensuring that essential human factors requirements are included early in the design of spacecrafts, transportation, and habitation units in order to optimize the effectiveness of the crew. Developing standards and countermeasures to optimize crew health, safety, and productivity is the catalyst for the URC research focus of identifying microorganisms and antimicrobial materials to optimize the spacecraft environment for space travel. The URC microorganism group seeks to learn how to identify and protect space travelers from the toxic effects of bacterial, viral, and fungal organisms. A second research focus is the genotoxicology studies to investigate the effects of toxic agents on biological systems in the space flight environment. These studies use technologies and approaches that examine the basic structure of the gene, changes in gene expression, detection of DNA damage and repair, the uses of genetic information in nanotechnology applications, and computational modeling approaches to elucidate cellular mechanism of microgravity induced stress. These genotoxic studies support the goals that are designed to address the fundamental role of gravity and cosmic radiation on vital biological, physical, and chemical systems in space; and to explore new technologies designed to identify and mediate the toxic components of space travel. The final URC objective is to improve the recruitment, and increase the rate of retention and graduation of minority students in undergraduate and graduate STEM programs. The URC approaches this overall objective through three programmatic thrusts: 1) upgrading the research infrastructure 2) recruiting and retaining high achieving students, and 3) faculty development. Projects: “Identification of Major Space Genes”: This project is identifying major genes and major cellular pathways that are altered by microgravity. Jade Clement, MD/PH.D., Principal Investigator “Utilization of Antimicrobial Natural Products for Management of Microorganisms in Space Life Support System”: This project is investigating the possibility of embedding natural antimicrobial chemicals into materials and fabrics, including membrane and filter materials for water purification, to prevent the growth of microorganisms. Molecular modeling will be used to enhance the selectivity and potency of the natural products. Mahmoud Saleh, Ph.D., Principal Investigator “Management of Microorganisms in a Closed Environment”: This project focuses on yeast cells as a model for nanotechnology and functional genomic studies. Information gained will be used to devise methods to identify and manage microorganisms in the space travel environment. Olufisayo Jejelowo, Ph.D., Principal Investigator “The Effect of Radiation and Microgravity on the DNA Repair Capacity of Lymphocytes”: This project uses the host-cell reactivation assay to determine the effects of radiation on DNA repair capacity in both G1 and microgravity environments. James DuMond, Ph.D., Principal Investigator 7 TEXAS INSTITUTE FOR INTELLIGENT BIO-NANO MATERIALS AND STRUCTURES FOR AEROSPACE VEHICLES ESTABLISHED DATE: AUGUST 2002 DIRECTOR(S): DR. OLUFISAYO JEJELOWO PHONE: 713-313-7841 NASA through the Texas Institute of Intelligent Bio-Nano Materials and Structures for Aerospace Vehicles (TiiMS) is bringing together some of the top researchers in Texas and the world — including a Nobel laureate and several members of the National Academies — in biotechnology, nanotechnology, biomaterials and aerospace engineering to develop the next generation of bio-nano materials and structures for aerospace vehicles. TiiMS was one of only seven University Research, Engineering and Technology Institutes chosen throughout the United States. TiiMS universities are Texas Southern University, Texas A. M University, Prairie View A&M University, Rice University, the University of Houston and the University of Texas at Arlington. Birds have long been the inspiration for aircraft, but modern, man-made aerospace vehicles seem primitive compared to Mother Nature's flying creatures. To be more like birds, the next generation of aerospace vehicles requires ultralight, ultrastrong composite materials that are multifunctional, with features such as computing and sensing capabilities engineered directly into them. And that’s what TiiMS is aiming for RESEARCH TiiMS will integrate basic research across the family of disciplines, leading to proof-of-concept experiments that will enable reconfigurable wings and adaptive space structures that embody concepts for advanced autonomous intelligent systems. Through a sequence of experiments of increasing sophistication, the nano materials, sensing, actuation, and structures technology will be developed and demonstrated for a new generation of air and space vehicles. The five research thrusts: Functionalized Nanomaterials Multifunctional Material Systems Multiscale Modeling Biomaterials and Devices Intelligent Systems PROJECTS AT TSU: PI: Olufisayo Jejelowo, Ph.D. Biomaterials and Devices Thrust Biochemical Sensors Unit Develop Biochemical Sensors for Life Detection and for Monitoring Microgravity and Radiation Effects. To enable/enhance autonomous environmental monitoring and control. Contact Information Olufisayo Jejelowo TSU Department of Biology 713-313-7841 jejelowo_oa@tsu.edu PI: Jade Clement, M.D., Ph.D. Biomaterials and Devices Thrust Biochemical Sensors Unit Study Toxicity of Carbon Nanotubes and Functionalized Nanomaterials Contact Information Jade Q. Clement TSU Department of Chemistry 713-313-1044 clement_jq@tsu.edu For additional Information visit the TiiMS web site at http://tiims.tamu.edu/participants.html 8 CENTER FOR CARDIOVASCULAR DISEASES ESTABLISHED – 1999 DIRECTOR: DR. ADEBAYO OYEKAN PHONE: 713-313-4258 GOALS: To expand and strengthen the University’s biomedical research capabilities in order that significant contributions may be made to the improvement of the cardiovascular health status of all Americans, especially African Americans. The Center serves as the hub of research activities on cardiovascular diseases and houses faculty, graduate students and research personnel. The Center also provides intensive laboratory training experiences for both graduate students and undergraduates and serves as a site for structured and supportive faculty development. PROJECTS: Nitric oxide/cytochrome P450 interactions in the control of renal function and blood pressure, peroxisome proliferator activated receptors (alpha and gamma) in the pathogenesis of hypertension and renal failure, cyclooxygenase metabolites of arachidonic acid and cerebral flow in subarachnoid hemorrhage (stroke) and diabetes mellitus. CENTER OF EXCELLENCE IN HEALTH DISPARITIES RESEARCH: CARDIOVASCULAR DISEASE & STROKE ESTABLISHED – 2004 DIRECTOR: DR. ADEBAYO OYEKA PHONE: 713-313-7156 GOALS: To develop and implement a strong minority/majority institutional collaboration to address training and research development for minority investigators interested in health disparities research related to cardiovascular disease and stroke. To partner TSU with Baylor College of Medicine, Medical College of South Carolina, and St. Luke's Episcopal Health System to create a collaborative research infrastructure that will increase research capacity and help build a comprehensive infrastructure for health disparities research in the Texas Medical Center. To develop a "Best Practices" model for building research infrastructure and capacity to support health disparities research by, with, and for those that are disproportionately affected by health disparities. PROJECTS: The Administrative Core directs the Center of Excellence in Health Disparities Research (CEHDR), selects CEHDR Faculty Fellows, and supervises the evaluation of all CEHDR activities, budgets and reports. The Training Core uses on-site and off-site training to recruit, support, and mentor junior minority investigators in the areas of research design, development and implementation, with emphasis on analysis of racial and cultural factors related to health disparities research. The Community Outreach and Dissemination Core a) develops and disseminates culturally appropriate health information, b) encourages and equips community-based organizations and community residents disproportionately affected by health disparities to participate in clinical studies and evidence-base prevention and intervention activities, and c) sponsors educational outreach activities and seminars. The Research Core pairs CEHDR Faculty Fellows with seasoned investigators to facilitate the development of pilot research projects and ongoing research proposals that address racial disparities in health. 9 INSTITUTE FOR BIOMEDICAL AND HEALTH DISPARITIES RESEARCH EST., 1986 DIRECTOR: DR. BARBARA HAYES PHONE: 713-313-7380 GOALS: PROJECTS: To develop an institutional research infrastructure that will enable faculty to engage in investigations of diseases or conditions, which have a higher incidence of morbidity and mortality in minority populations. Core facility development in: molecular biology and tissue engineering; biosensor and biomarker technology; computational research; proteomics and genomics; and student development. Recruitment of biomedical research faculty and their development is another goal of the project. The Institute is supported by a grant from the National Institutes of Health, National Center of Research Resources, Research Centers in Minority Institutions Program. BIOSENSOR AND BIOMARKER TECHNOLOGY EST., 1991, EXP., 1999 AND 2004 DIRECTOR: DR. MAHMOUD A. SALEH PHONE: 713-313-1912 ASSISTANT DIRECTOR: DR. XIN WEI PHONE: 713-313-1911/7013 SUPPORT: NIH / NCRR/ RCMI PROGRAM The Facility provides technical and resource support as well as hands-on-training in molecular and biochemical techniques for environmental and biomedical investigators. The main objectives of the BBT are to provide essential research infrastructure to: 1) meet anticipated investigators’ needs for sophisticated techniques in advanced biomedical study; 2) improve the research capabilities and competitiveness of TSU faculty investigators; and 3) strengthen the Environmental Toxicology Program and the related study in areas of biosensor and biomarker technologies. BBT provides analytical methods for determining biomarkers and environmental contaminants. It also provides services such as the isolation of proteins/toxicant adducts and characterization of biomarkers of exposure. The research work has been focused on environmental contaminants in Lake Houston, Galveston Bay, and the Houston Ship Channel. The current research foci of the faculty investigators are: (1) Cellular and Molecular Environmental Toxicology (molecular and cellular mechanisms of gene regulation under various conditions of environmental stress); (2) Molecular Mechanisms for Initiation of Cancer by Occupational and Environmental Endocrine Disruptors (the role of estrogen in the initiation of cancer); (3) Molecular Mechanism(s) of Metal Toxicity (study of low-level exposure to metal mixtures that alters brain-signaling mechanisms); (4) Brain Toxicants in Neural Injury and Degeneration (effects of environmental toxicants and ionizing radiation on brain cells and risk assessment by markers of neuronal injury and degeneration); and (5) Biocomposite Materials and Biosensing Technology (interdisciplinary material study of functional composites consisted of bioactive species and synthetic polymers). The BBT Core is equipped with state-of-the-art facilities, including multiple pieces of gas chromatography, HPLC and GC-MS, electrophoresis, protein sequencers, freeze dryers, optical and electron microscopes, FT-IR, UV-Vis and fluorescence spectrophotometers, comprehensive electrochemical workstations, modulated differential scanning calorimeter, dynamic mechanical thermal analyzer and tensile tester. COMPUTATIONAL RESEARCH LABORATORY EST., 2004 DIRECTOR: DR. CHRISTOPHER TYMCZAK PHONE: 713-313-1849 AISSISTANT DIRECTOR: DR. RAMBIS CHU PHONE: 713-313-7919 SUPPORT: NIH / NCRR/ RCMI PROGRAM The Computational Research Laboratory (CRL) provides support for the training of informatics scientists to enable them to perform research and to apply informatics to any area of biomedical research, including basic biomedical research, clinical medicine, health services research, public health, professional education, and administration. This core facility enhances the data mining and data visualization capabilities of TSU faculty and students, manages and shares 10 biomedical research related data sets, and promotes collaboration among RCMI and non-RCMI investigators engaged in biomedical and health disparities research through seminars and the development and use of a collaborative computations-based research network. The CRL currently applies information technology to enable the collection, manipulation, and organization of massive data sets for biomedical and health disparities research. The CRL is also developing new computer software to process that data and is developing better mathematical models and simulations to make predictions that may replace and/or improve experiments. These tasks necessitate the use of extensive computing capabilities which have required the acquisition of state-of-the-art computer hardware and software components. MOLECULAR BIOLOGY AND TISSUE ENGINEERING CORE FACILITY EST., 1996, EXP., 1999 AND 2004 DIRECTOR: DR. KASTURI RANGANNA PHONE: 713-313-1886/7554 ASSISTANT DIRECTOR: AMRUTHESH SHIVACHAR PHONE: 713-313-1886/7554 SUPPORT: NIH / NCRR/ RCMI PROGRAM The MBTE facility consists of two components: Molecular Biology (MB) and Tissue Engineering (TE) component and is established in the College of Pharmacy and Health Sciences (COPHS) at Texas Southern University. The facility provides molecular, cellular and tissue engineering research infrastructure to support biomedical research activities. The core facility resources facilitate the conducting of advanced biomedical research that assists in unraveling many basic questions related to health disparities such as vascular diseases, diabetes, cancer, and neurological disorders, which disproportionately affect African Americans. The facility supports state-of-the-art biomedical research and is equipped with multipurpose imaging system, fluorescence microscope, flow cytometer and bioreactors PROTEOMICS AND FUNCTIONAL GENOMICS CORE FACILITY (RCMI) EST., 2004 DIRECTOR: DR. JAMES W. DUMOND PHONE: 713-313-7095 SUPPORT: NIH / NCRR/ RCMI PROGRAM The major goals of the Genomics and Proteomics facility at Texas Southern University is to provide the physical and human infrastructure to support research in the fields of genomics and proteomics, and to link to the bioinformatics and computational core. The facility maximizes opportunities for communications and collaboration among the many departments and disciplines at TSU and between TSU scientists and their colleagues’ institutions at the Texas Medical Center. The facility will develop a graduate research and training program that responds to current and future needs of the field. This involves continued creation of course materials for the current curriculum as well as specialized courses, training sessions and hands-on workshops. In addition, the facility will sponsor monthly in-house seminars and an annual symposium. Furthermore, the scientists affiliated with the facility are committed to developing and applying cutting-edge technologies that will benefit human and social endeavors. Proteomics and Genomics core will provide several service and research resources, such as DNA microarray using chip technology, DNA sequencing, Real Time PCR, Peptide Synthesis, 2-D Proteomics analysis. 11 ROBOTICS LABORATORY ESTABLISHED: 2005 DIRECTOR: DR. SEYED ROOSTA PHONE: 713-313-7903 GOALS: To offer opportunities for interdisciplinary studies and research in technology and science, leading to innovative projects that address the problems in embedded systems, robotics, flexible manufacturing systems, computer aided-design and manufacturing. PROJECTS: The Robotics Laboratory provides support for training and research in science and technology. This facility will develop a graduate research and training program that responds to the current and future needs of the computer science area, such as industrial robotics and computer-aided design and manufacturing. Some of the projects associated with this facility are: Robot Programming, Path Planning, AirTraffic Control Systems, Battle-Mission Systems and Virtual Networked Environment. Furthermore, the faculty affiliated with the facility are committed to develop and apply cutting-edge technologies that will benefit students. Some of the potentials associated with this facility are: integration of robotics in Artificial Intelligence, integration of industries and science, such as Flexible Manufacturing Systems and Computer Aided-Design and Manufacturing. 12