Identification of Organic Compounds
CHEM 4420-01
Fall 2007
Prereq.: CHEM 3362
Advanced study of common spectrometric techniques for identifying organic compounds.
Emphasis on interpretation of data obtained from Infrared Spectroscopy (IR), Mass
Spectrometry and Nuclear Magnetic Resonance (NMR), including two-dimensional NMR.
Professor:
Office Hours:
Email:
IM:
Kevin P. Gwaltney, Ph.D. (aka Dr.G)
By appointment (phone, email, after class)
kgwaltne@kennesaw.edu
MoonshadowG (AIM, MSN, Yahoo!)
Phone:
Office:
770-423-6504
SC 421
Texts:
Spectrometric Identification of Organic Compounds, 7th ed.
Silverstein, Webster, Kiemle
(required)
Structure Determination of Organic Compounds : Tables of
Spectral Data, 3rd ed. Pretsch, E., Bühlmann, P., Affolter (recommended)
9:30 a.m. – 10:45 a.m.
Lecture:
T R (T TH)
Absences:
Student is responsible for all information and assignments from each lecture.
EARLY OR LATE EXAMS WILL NOT BE ALLOWED. A drop is provided if
a student is late or absent from one exam due to unavoidable circumstances.
Exams begin at 9:30 a.m. and must be completed within time listed.
Exams:
1
2
3
Final
Presentation:
Present (15 min.) the interpretation of spectral data from the experimental
section(s) of Journal of Organic Chemistry article(s). Article(s) must be
approved by Dr. Gwaltney (first come, first serve) by November 1, 2007.
Once approved, each student must post article reference(s) on Vista in JACS
format. Presentations must be produced using PowerPoint® and must include
interpretation for more than one molecule. An outline of the presentation
must be submitted by November 8, 2007, a draft must be submitted by
November 15, 2007, and the final PowerPoint slides must be submitted by
November 27, 2007. Be prepared to answer questions and discuss your
interpretation. Presentations will be on November 27 and 29, and December
4. More details to follow.
Grading:
Practice and Assignments
Exams
Presentation
Final Exam
Total
Thursday
Thursday
Tuesday
Tuesday
SC 212
September 27
October 25
November 20
December 11
100
200***
50
50
400 pts.
1 hour 10 minutes
1 hour 10 minutes
1 hour 10 minutes
1 hour 50 minutes
*** One (1) Lowest Exam will be
dropped.
Points: 400 to 358
Grade:
A
357.5 to 318
B
317.5 to 278
C
277.5 to 238
D
238 >
F
Ranges may be widened based on class performance.
Integrity:
Every KSU student is responsible for upholding the provisions of the Student
Code of Conduct, as published in the Undergraduate Catalog. Section II of
the Student Code of Conduct addresses the University’s policy on academic
honesty, including provisions regarding plagiarism and cheating, unauthorized
access to University materials, misrepresentation / falsification of University
records or academic work, malicious removal, retention, or destruction of
library materials, malicious / intentional misuse of computer facilities and / or
services, and misuse of student identification cards. Incidents of alleged
academic misconduct will be handled through the established procedures of
the University Judiciary Program, which includes either an “informal”
resolution by a faculty member, resulting in a grade adjustment, or a formal
hearing procedure, which may subject a student to the Code of Conduct’s
minimum one semester suspension requirement.
Suspicious behavior can get you in trouble. Keep your eyes on your own
paper and prevent students from seeing your paper during Exams. Nonmedical electronic devices may not be used during an exam.
Withdrawal:
"W" grades on your transcript are a negative factor in evaluating your
academic performance. Some professional schools go through a transcript
and substitute "F" for every "W" and recalculate the GPA. For anyone serious
about a professional or graduate school of any kind, I would recommend that
your transcript should show no more than 4 "W" grades. Even if you have
only 4 "W's" when you graduate, you should have an excellent reason for
each one of them (sickness, death in the family, etc.).
Please take your academic experience very seriously, and have a frank
discussion with an advisor about your strengths and weaknesses so that you
devote your precious time and energy to pursuits best suited to you. I will do
what I can to help you all, but you have to do your part.
Learning Outcomes:
Recognize and discuss emerging technologies.
Advance the student’s knowledge in a specialized area of Chemistry.
Integrate and evaluate knowledge gained in required Chemistry courses .
Proficient use of a variety of databases, including Chemical Abstracts, MSDS sites, and
other search engines.
Interpret and critique the recent literature in the specialized area of Chemistry.
Effectively communicate, in writing and presentation(s), and defend analysis of a problem
or article in the specialized area of Chemistry thereby displaying a greater comprehension
of Chemistry.
Tentative Schedule
Sections
Date(s)
3.1-3.3
3.4
3.5-3.6
8/16 - 8/28
8/30 - 9/6
9/11, 9/13
3.8, 3.10-3.14, 3.7, 3.9
3.15-3.16
9/18, 9/20
9/25
Proton Magnetic Resonance Spectrometry (1H NMR)
Introduction, Instrumentation
Chemical Shift
Integration, Splitting
1H
NMR continued
Equivalence, Coupling
Other, Summary, Practice
Exam 1
9/27
Carbon-13 NMR Spectrometry (13C NMR)
Sample Preparation, Broad-Band Decoupled Spectra,
Chemical Shift, DEPT, APT, etc.
4
10/2 - 10/9
Infrared Spectroscopy (IR)
IR Absorption, Instrumentation, Sample Preparation,
Functional Groups, etc.
2
10/11, 10/16
Mass Spectrometry (MS)
Instrumentation, Sample Preparation, Ionization: EI, CI,
FD, FAB, ESI, MALDI, Molecular Formula Determination,
Fragmentation, Spectra by Chemical Class, etc.
1
10/18, 10/23
Exam 2
10/25
Article(s) Submitted for Review
11/1
Presentation Outline Submitted for Grading
11/8
Correlation NMR Spectrometry (2D NMR)
1H-1H COSY, 1H-13C COSY: HETCOR, 13C-13C:
INADEQUATE, etc.
5
PowerPoint Slides Submitted for Grading
NMR Spectrometry of Other Important Spin ½ Nuclei
15N, 19F, 29Si, 31P
10/30 - 11/13
11/15
6
11/15
Exam 3
11/20
Final PowerPoint Slides Submitted for Grading
11/27
Presentations
Final Exam
11/27 - 12/4
12/11