BRIEF CURRICULUM VITAE ATHANASIOS E RAPTIS, MD, PhD. ASSOCIATE PROFESSOR OF INTERNAL MEDICINE-DIABETES MELLITUS FACULTY OF MEDICINE NATIONAL & KAPODISTRIAN UNIVERSITY OF ATHENS Personal Information Address: 2nd Department of Internal Medicine-Propaedeutic, Research Institute and Diabetes Center, Attikon University Hospital, 1 Rimini str., 12462 Athens, Greece tel.: +30-210 5832357 fax: +30-210 58319127 e-mail:atraptis@med.uoa.gr e-mail: atraptis@otenet.gr Education Athens University Medical School. Postgraduate -Doctoral Thesis in Athens University Medical School Titles 'Clinical and Biochemical Parameters after prolonged administration of semisynthetic human insulin in newly diagnosed insullin-dependent diabetics. Comparative study with purified insulin". -I was granted with a scholarship by " Alexandros Onassis" foundation ( Oct.1983 - Sept.1984 ) -I was granted with a scholarship by " Hellenic Diabetic Association" ( April 1995 - April 1997 ) Speciality Internal Medicine Subspeciality Diabetes Mellitus Previous Employment 1981 Nov.- 1982 Sept.: Research Fellow in Diabetes Center - Artificial Pancreas Unit of the Department of Clinical Therapeutics in"Alexandra Hospital", Athens University. 1982 Nov.- 1985 Mar.: Research Fellow in the 2nd Department of Internal Medicine Propaedeutic,of Athens University in "Evangelismos Hospital" ( Chairman:Professor S.A.Raptis M.D.). 1985 Apr.- 1987 Jan.: Served as a Doctor in the Armed Forces (July 1985 - March 1986, Resident in the Department of Internal Medicine of 218 Military Hospital, April 1986 - January 1987,Resident in the Department of Internal Medicine of 401 Military Hospital). 1987 Mar.-1988 Febr.: State Doctor in rural area for one year (Obligatory). 1988 Mar.- 1989 Mar.: Research Fellow in the 2nd Department of Internal Medicine Propaedeutic of Athens University, "Evangelismos Hospital" 1989 Apr.- 1992 Oct.: Resident in the 2nd Department of Internal Medicine, Propaedeutic of Athens University,"Evangelismos Hospital" 1992 Nov.- 1994 Mar.: Research Fellow in the 2nd Department of Internal Medicine Propaedeutic of Athens University, "Evangelismos Hospital" 1994 Mar.- 1995 Apr.: Registrar in the 2nd Department of Internal Medicine Propaedeutic of Athens University,"Evangelismos Hospital" 1995 Apr. - 1997 Apr.: Honorary Research Fellow in the Unit for Metabolic Medicine of London University, Guy's Hospital, U.K. (Chairman: Professor GianCarlo Viberti) 1997 Apr. – 2002 Jul : Registrar in the 2nd Department of Internal Medicine Propaedeutic of Athens University,"Evangelismos Hospital" 2002 Jul. – 2003 Nov : Lecturer in the 2nd Department of Internal Medicine Propaedeutic of Athens University,"Evangelismos Hospital" 2 2003 Nov. –2007 Aug : Lecturer in the 2nd Department of Internal Medicine Propaedeutic of Athens University,"Attikon Hospital" 2007 Aug. –2012 Sept : Assistant Professor in the 2nd Department of Internal Medicine Propaedeutic of Athens University,"Attikon Hospital" 2012 Sept. - Today : Associate Professor in the 2nd Department of Internal Medicine Propaedeutic of Athens University,"Attikon Hospital" Special Fields - Diabetes Mellitus of Study - Hypertension - Diabetic Nephropathy Membership of - European Association for the Study of Diabetes (EASD) Scientific - Hellenic Diabetological Association Society - Hellenic Association of Internal Medicine - Hellenic Transplantation Society - General Medical Council (GMC) I have received the Good Clinical Practice (GCP) training 3 PAPERS 1. a)Raptis S., Hadjidakis D, Enzmann F, Raptis A, Diamantopoulos E, Rosenthal J Inhibition of pancreatic glucagon-responses to arginine by human insulin (recombinant DNA) and purified porcine insulin in normal and diabetic subjects DIABETES CARE 5: 93-101 Suppl. 2, 1982 b)Raptis S., Hadjidakis D, Enzmann F, Raptis A, Diamantopoulos E, Rosenthal J Inhibition of pancreatic glucagon-responses to arginine by human insulin (recombinant DNA) and purified porcine insulin in normal and diabetic subjects MUNCHENER MEDIZINISCHE WOCHENSCHRIFT,125,38-43, Suppl. 1, 1983 2. Dimitriadis G, Raptis S, Raptis A, Hatziagelaki E, Mitrakou A, Halvatsiotis P, Ladas S, Hillebrand I Effects of 2 new alpha-glucosidase inhibitors on glycemic control in patients with insulindependent diabetes-mellitus KLINISCHE WOCHENSCHRIFT 64 (9): 405-410 May 2 1986 3. Hadjidakis DI, Raptis SA, Raptis AE, Karaiskos C, Souvatzoglou A, Diamantopoulos EJ The antidiabetic action of somatostatin-28 as assessed by the artificial endocrine pancreas - greater potency than somatostatin-14 HORMONE AND METABOLIC RESEARCH 19 (11): 574-578 NOV 1987 4. Raptis AE, Tountas N, Yalouris AG, Hadjidakis D, Zaharis A, Miras K, Raptis SA Comparative-study of the therapeutic effects of glibenclamide or the fixed combination of glibenclamide - phenformin with those of gliclazide or chlorpropamide ACTA DIABETOLOGICA LATINA 27 (1): 11-22 Jan-Mar 1990 5. Raptis AE, Tountas NB, Yalouris AG, Halvatsiotis PG, Raptis SA Therapeutic effect of glibenclamide in a fixed combination with metformin or phenformin in NIDDM patients HORMONE AND METABOLIC RESEARCH 28 (2): 89-94 FEB 1996 6. Raptis AE, Spring MW, Viberti G Comparison of blood pressure measurement methods in adult diabetics LANCET 349 (9046): 175-176 JAN 18 1997 7 . Mitrakou A, Tountas N, Raptis AE, Bauer RJ, Schulz H, Raptis SA Long-term effectiveness of a new alpha-glucosidase inhibitor (bay m1099-miglitol) in insulin-treated type 2 diabetes mellitus DIABETIC MEDICINE 15 (8): 657-660 AUG 1998 8 . Raptis SA, Hatziagelaki E, Dimitriadis G, Draeger KE, Pfeiffer C, Raptis AE Comparative effects of glimepiride and glibenclamide on blood glucose, c-peptide and insulin concentrations in the fasting and postprandial state in normal man EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES 107 (6): 350-355 1999 9. Raptis AE, Viberti G Pathogenesis of diabetic nephropathy 4 EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES 109: S424-S437 Suppl. 2 2001 10. Hadjidakis DJ, Mylonakis AM, Sfakianakis ME, Raptis AE, Raptis SA Diabetes and premature menopause: is their co-existence detrimental to the skeleton? EUROPEAN JOURNAL OF ENDOCRINOLOGY 152 (3): 437-442 MAR 2005 11. Hadjidakis DJ, Raptis AE, Sfakianakis ME, Mylonakis AM, Raptis SA. Bone mineral density of both genders in type 1 diabetes according to bone composition. JOURNAL OF DIABETES AND ITS COMPLICATIONS, Sep-Oct;20(5):302-7,2006 12. Kyriakides Z. S, Kremastinos D., Raptis A. E., Kyrzopoulos S., Raptis S. A., Sbarouni E., Johnston N., Webb D. J Impaired effect of endogenous endothelin-1 on coronary artery stiffness in patients with type II diabetes mellitus. INTERNATIONAL JOURNAL OF CARDIOLOGY, Sep 20 ; 112(2):207- 12, 2006 13. Hadjidakis DI, Androulakis II, Mylonakis AM, Sfakianakis ME, Raptis AE, Papaefstathiou AG, Economopoulos TC, Raptis SA. Diabetes in postmenopause: different influence on bone mass according to age and disease duration. EXP CLIN ENDOCRINOL DIABETES. May;117(5):199-204, 2009 14. Mitrou P, Boutati E, Lambadiari V, Tsegka A, Raptis AE, Tountas N, Economopoulos T, Raptis SA, Dimitriadis G. Insulin resistance in hyperthyroidism: the role of IL6 and TNF alpha. EUR J ENDOCRINOL. Jan;162(1):121-6, 2010 15. Mitrou P, Raptis AE, Lambadiari V, Boutati E, Petsiou E, Spanoudi F, Papakonstantinou E, Maratou E, Economopoulos T, Dimitriadis G, Raptis SA. Vinegar decreases postprandial hyperglycemia in patients with type 1 diabetes. DIABETES CARE. Feb;33(2):e27, 2010 16. Dimitriadis G, Boutati E, Raptis AE, Hatziagelaki E, Mitrou P, Lambadiari V, Tountas N, Economopoulos T, Raptis SA. Subcutaneous glucose monitoring with GlucoDay: comparison of the results to those obtained with the endocrine artificial pancreas. HORMONES (Athens) Apr-Jun;9(2):145-50, 2010 17. Lambadiari V, Mitrou P, Maratou E, Raptis AE, Tountas N, Raptis SA, Dimitriadis G. Thyroid hormones are positively associated with insulin resistance early in the development of type 2 diabetes. ENDOCRINE. Feb;39(1):28-32, 2011 18. Dimitriadis G, Hatziagelaki E, Mitrou P, Lambadiari V, Maratou E, Raptis AE, Gerich JE, Raptis SA. 5 Effect of Hyperthyroidism on Clearance and Secretion of Glucagon in Man. Exp Clin Endocrinol Diabetes. Apr 119(4), 214-217, 2011 19. Raptis A., Markakis K., Mazioti M., Raptis S., Dimitriadis G. What the radiologist needs to know about the diabetic patient Insights Imaging 2:193-203, 2011 20. Raptis AE, Bacharaki D, Mazioti M, Marathias KP, Markakis KP, Raptis SADimitriadis GD, Vlahakos DV. Anemia due to Coadministration of Renin-Angiotensin-System Inhibitors and PPARγ Agonists in Uncomplicated Diabetic Patients. Exp Clin Endocrinol Diabetes. Mar 22., 2012 21. Lambadiari V, Mitrou P, Maratou E, Raptis A, Raptis SA, Dimitriadis G. Increases in muscle blood flow after a mixed meal are impaired at all stages of type 2 diabetes. Clin Endocrinol (Oxf). Jun;76(6):825-30.,2012 22. Kontoangelos K, Raptis AE, Papageorgiou CC, Tsiotra PC, Papadimitriou GN, Rabavilas AD, Dimitriadis G, Raptis SA. Oxytocin and psychological factors affecting type 2 diabetes mellitus. Exp Diabetes Res. 2012;2012:560864. Epub 2012 Sep 10. 23. Kontoangelos K., Raptis A.E., Papageorgiou C.C., George N.Papadimitriou G.N., Rabavilas A.D., Dimitriadis G., 2 and Raptis S.A. The association opf the metabolic profile in diabetes mellitus type 2 patients with obsessive compulsive disorder and depression : New insights International Journal of Psychiatry in Clinical Practice 2013 Feb;17(1):48-55. Kontoangelos K, Raptis AE, Papageorgiou CC, Tsiotra PC, Papadimitriou GN, Rabavilas AD, Dimitriadis G, Raptis SA. Oxytocin and psychological factors affecting type 2 diabetes mellitus. Exp Diabetes Res.;2012:560864. Epub 2012 Sep 10., 2012 6