FAQ Regarding Guidelines 2005 ACLS Course Florida Regional ECC Last updated October 18, 2006 The following is a compilation of questions/concerns regarding the new guidelines ACLS course. Following the number of the question, you’ll see a category of question, such as “science”, “administrative”, “course structure”. Some of the answers come from Judy Young, Florida ACLS NF, others are from National ECC and/or the ACLS Subcommittee, and still other answers are combination answers from National and Judy Young. When answers are from someone other than Judy, they are noted as such. Some of the questions were graciously shared from other states, and answered by National ECC or that state’s NF. This FAQ document will be sent to all Florida ACLS TCs and RFs as it is updated. Number Question/Concern The ECC Handbook (p.45) states that Amiodarone is only 1. Science indicated for ventricular tachycardia/arrhythmia when pt is hemodynamically unstable or when other antiarrhythmic agents (or alternative agents) have not been tolerated. The AHA Guidelines for CPR and ECC (p. IV-74) states that Amiodarone IV may be given for narrow-complex tachycardias that originated from a reentry mechanism if the rhythm remains uncontrolled by adenosine, vagal maneuvers, and AV nodal blockade in patients with preserved or impaired ventricular function (class IIb). My question is can we use Amiodarone in stable narrow complex tachycardia if adenosine and vagal maneuvers don't work? 2. How much time do we have to wait before giving epinephrine after vasopressin in cardiac arrest? Is it 3-5 minutes or 10 minutes? Science Answer I believe the intent is not to give the Amiodarone in narrow complex tachycardias in the initial management of the case, but that this drug may be of use by an expert after "expert consultation". Amiodarone is not listed on the narrow complex side of the algorithm in either the handbook or the Guidelines 2005 book, AND, it is not in the algorithm in the new ACLS provider manual. One thing the NF were told when we received the first science briefings, was that not ALL scientifically significant findings found their way into the guidelines and algorithms. So, bottom line, I believe the statement you quote from the guidelines book meant that after expert consultation, Amiodarone may be used for narrow complex tachycardias in patients with preserved or impaired ventricular function. The drug is not to be taught as part of the narrow complex tachycardia algorithm. The 40 unit dose of vasopressin may be used instead of either the first or second dose of epinephrine, then continuing with the 3-5 minute administration of epinephrine. So, if you give the vasopressin as the first dose, you may then administer the epinephrine 3-5 minutes later. If you give the vasopressin as the 2nd dose, you still may administer epinephrine again 3-5 minutes later and so on. We know it takes approximately 10 minutes for the vasopressin to start to work, peaking at perhaps 20 minutes. 1 There is a study (Guyett FX, in Resuscitation 2004) that showed an increase in ROSC in patients with asystole who received combination administration of both epinephrine and vasopressin. You do not repeat the vasopressin, just give the single dose of 40 units. 3. Admin 4. Science On our hospital’s Code Blue sheet, the amount of time it takes until the patient is intubated is recorded. Our hospital uses AHA ACLS guidelines and the goal to intubation time of 3 minutes. With the new guidelines emphasizing BLS and hands on time, has the amount of time to intubation guideline been changed? There really is not a "time" by which endotracheal intubation must be done. You'll see that the new course allows for individualization of the airway management station. For example, folks that don’t perform ET intubation as part of their job don't have to be trained and evaluated on inserting ET tubes, but they ARE trained and tested on adequately managing the airway. So, I don't think we'll find a recommended number of minutes from CPR to intubation. I know that the NRCPR, from AHA, is updating its checklists, etc, and these should be complete soon. Send NRCPR questions to: scott.strader@heart.org. So, just as a suggestion, I think you might want to consider deleting a "time" requirement on your checklist, and instead add something like, "Were adequate ventilations performed with CPR", and "Was advanced airway management considered within 3 minutes of CPR initiation". Just some thoughts, but more importantly than actual ET intubation, is the adequacy of whatever form of ventilation is being used. Does the biphasic shock at 200J increase to 360J after the first shock if there is no change or does it remain at 200J throughout the code? Please refer to page IV-37 in 2005 Guidelines for CPR and ECC, section titled, "Fixed and Escalating Energy". Bottom line is that multiple prospective human clinical studies and retrospective studies have failed to identify an optimal biphasic energy level for first or subsequent shocks. Therefore, AHA doesn’t make a definitive recommendation for the selected energy for the first or subsequent biphasic defibrillation attempts. There is a recommendation, however, based on documented evidence from two different types of biphasic waveforms: 150 J to 200 J with biphasic truncated exponential waveforms and 120 J with a rectilinear biphasic waveform--but these are only for the initial shock. None of the available evidence has shown superiority of either nonescalating or escalating energy biphasic waveform defibrillation for termination of VF. So, AHA states, "Nonescalating and escalating energy biphasic waveform shocks can be used safely and effectively to terminate short-duration and long-duration VF (class IIa)." You'll note that the "Pulseless Arrest" algorithm 2 indicates the dosages I've listed above, but states that if you don't know if you have Truncated or Rectilinear waveforms, just start at 200 J on the biphasic defibrillator. Also, the algorithm states that you may continue subsequent shocks at the same or higher doses...your call. (This is in box 6 of the Pulseless arrest algorithm). 5. Science Why is it listed in the handbook under PALS to administer adenosine for V-Tach? Shouldn't it be Amiodarone or Lidocaine like in an adult? What is the science behind this? Adenosine is used for narrow complex SVTs and why the change, is this a misprint? (From Judy, ACLS NF) I'll refer you to page IV-175-178 in the 2005 Guidelines for CPR and ECC book, section "Tachycardia and Hemodynamic Instability". For many years now in adults, there has been a recommendation that when there is wide-complex tachycardia, Adenosine MAY be tried if there is suspicion that the wide-complex tachycardia is SVT with aberrancy. Because of the short half-life of Adenosine, it was OK to do this as long as we didn't delay cardioversion if necessary. In the PALS "Tachycardia with Pulses and Poor Perfusion", this is the same suggestion, however, the text goes on to say, "If a second shock is unsuccessful or if the tachycardia recurs quickly, consider antiarrhythmic therapy (amiodarone or procainamide) before a third shock" (Box 11 in the algorithm with expert consultation advised). Now, you'll notice that in the algorithm for "Tachycardia With Adequate Perfusion", Adenosine is not included in the treatment of wide-complex tachycardia. In the unstable scenario, there isn't time for Amiodarone or Procainamide, and electricity is the recommended treatment. Because the adenosine is so quick, one could "try it" while preparing the defibrillator. In this stable scenario, however, we aren't proceeding to electricity, and there is time for the Amiodarone or Procainamide. You'll also note that if these are ineffective, with expert consultation, the algorithm eventually leads you back to the treatment recommendations for SVT (and in this case it would be wide, possibly an aberrancy) where you'll find vagal maneuvers and adenosine listed. Cardioversion would be a last decision in this case, as it is stable. (From Ed, PALS NF) As you know, the most likely of SVT or VT in a child is SVT. The reason that adenosine is mentioned in the " Possible Ventricular Tachycardia" algorithm is that, if it is actually SVT, you may correct it in seconds &, if not, you have done no harm as the medicine is out of the system in 2 seconds. You notice that we stated that adenosine "may be attempted if it does not 3 delay electrical cardioversion". Basically we're admitting that it may be difficult to differentiate between SVT & VT so if you have time you can attempt the least invasive, and painful, modality. If it works, great; if not, you've lost nothing. In adults, with the average slower rate of SVT & VT, it is somewhat easier to differentiate one from the other and we can be more sure in diagnosis and specific in treatment. 6. Structure Is there a separate rhythm test in the new ACLS course like we had previously, or are rhythms included in the written exam? To answer your question, there are three "tests" in the new ACLS course: 1) BLS skills testing; 2) the written exam, which does include the rhythm strips; and 3) megacode testing. You'll also note, when you get your provider manuals that the students are to complete a rhythm self-assessment program, and a pharmacology self-assessment program PRIOR to attending the ACLS course. The intent of this self-assessment is that the students arrive for the ACLS course with a background knowledge of these two topics. The course is not designed to teach these two subjects in detail during the course. Lastly, I just want to be sure you are aware that in the "old" ACLS course we were not permitted to require that a student "pass" a locally developed rhythm test, as part of their passing the ACLS course. We were permitted to administer rhythm tests as training tools, but failure to pass these could NOT be used as pass or fail for the course. Now, with that said, if the student couldn't recognize rhythms on the monitor and therefore couldn't appropriately treat the rhythm during skills evaluation (such as in megacode testing stations), certainly that was grounds for failure. But a locally developed written rhythm test could not be included in the pass or fail scores of the student. 7. Structure Why no stroke or ACS in the ACLS renewal course? In fact, the renewal course doesn’t include learning stations for the individual rhythm cases, such as tachycardias, bradycardias, etc. It focuses on “what’s new”, mostly the science, BLS and airway stations then the Megacode teaching and testing stations. Jo Haag explained that in order to keep the renewal course to 1 day, AND to teach and test the 2005 Guidelines BLS skills, ACS and Stroke were left out. However, she continued with the statement that a TC had the option of adding sections of the course as needed. So, if a 4 renewal class of students work in the ER, EMS, ICU, etc., and deal with ACS and stroke frequently, the TC may want to include the videos for these two cases. If a facility is a Stroke Center, surely it will want to have Stroke included in the renewal course. It may lengthen the hours of the course somewhat. So, bottom line, the renewal is mostly to teach new BLS skills, and "reverify" megacode skills using new guidelines. You may add cases as desired. 8. Admin 9. Structure 10. Structure 11. Admin May we make copies of the ACLS self-assessment test? One TC said that some students had trouble opening that document with their own computers and it would be so helpful if she could hand them a hard copy when they pick up the book. National doesn't want us to make copies of the self-assessment quiz. Jo explained that the instructions Drenda sent out should be enough. I told her that I had to download a newer version of Netscape to get it to open on my computer, but she is certain that the instructions for opening should fix the problem. If students continue to have problems opening this, I'll go back to National with a request to make hard copies of the self-assessment. Many of you have questioned the instructor-student ratio of the new ACLS course for the airway and CPR-AED stations. The ACLS materials recommend 1 instructor to 3 students (1:3) in these two stations. The instructor to student ratio for the remaining learning and testing stations in the course is 1:6. It has been noted that CPR-AED training in the BLS course recommends a ratio of 1:6. So, the question was why the 1:3 ratio in the ACLS course? I received clarification from National on this issue. The 1:3 ratio in these two stations is because of time constraints in these two stations. Every student must return demonstration in airway management, and every student must be evaluated on adult CPRAED skills. Many ACLS students may NOT have taken the new BLS course, so the CPR-AED station will involve teaching AND testing the new skills. The 1:3 ratio was designed to ensure that all students are tested in a reasonable rotation schedule. You may run these two stations with a ratio of 1:6 if you choose to do so. Just be sure that you allow enough time for each student to perform required skills. It is suggested that to accommodate the 1:3 ratio during the airway and CPR-AED stations, BLS instructors be used. Is this a requirement? This is NOT a requirement. You certainly may have all ACLS instructors teaching these stations. The suggestion for the BLS instructors is just to ease the strain on those TCs who may have limited ACLS instructors. Each provider manual comes with a pre-course preparation checklist that the student brings to the ACLS course, and turns in. For those who are permitted to library provider manuals, can this form be reproduced? This form may be reproduced for those of you that "library" the provider manuals. This form is also on the instructor network, and can be downloaded and reproduced for each student. You may NOT reproduce the CD that accompanies the provider manual. So, you will want to emphasize to the student that the manual be returned WITH the CD. 5 12. Science 13. Science 14. Structure In pulseless arrest (V-fib, asystole), do you have to follow Vasopressin with Epinephrine? I thought that Vasopressin was such a strong vasopressor that there was no need to follow it with Epinephrine. The intent is to ALWAYS give epinephrine as the pressor agent, and we MAY substitute either the first or second dose of epinephrine with one 40 unit dose of vasopressin. So, vasopressin will not be given alone. Indeed, vasopressin is a potent vasopressor; however it takes about 10 minutes to start working, and around 20 minutes for peak effect. Therefore, we are to continue with the epinephrine protocol after giving the dose of vasopressin. Most of the studies show that there is no real evidence that one is better than the other, it is just that the epinephrine works so much faster. There is a study (Guyett FX, in Resuscitation 2004) that showed an increase in ROSC in patients with asystole who received combination administration of both epinephrine and vasopressin. I have a question that needs clarification in ACLS regarding the use of Atropine. In the Handbook on page 46, it states specifically that Atropine 0.6-1mg IV repeated every 5 minutes is used in ACS. I cannot find this information in the Circulation publication about the use of Atropine for ACS. I understand that in the field, if someone had an MI and is bradycardic, that atropine may be used if the truck only has Epi and Atropine available, but I am unfamiliar with the dosage recommended. Can you provide any clarification on the use of Atropine in ACS, is it just for the bradycardic patient, or is it indicated for all MIs? (From the ACLS subcommittee/editors) I reviewed it and the sheet should say "discuss" atropine, prepare for pacing. The question we usually receive is "can we give atropine". This is a complicated question and, in part, is caused by the uncertainty in making a quick diagnosis in a symptomatic patient. As you know, AV blocks are the most difficult rhythms for ACLS providers. For example, Mobitz 2 is often incorrectly diagnosed (by ACLS P) when it is in fact 2:1 AV block, or apparent Mobitz II but with a narrow QRS. It is the infranodal Mobitz II with a wide QRS that will not respond to a vagolytic drug. Other second degree blocks may respond depending on their site of origin. So, say "discuss" atropine. This would enable discussion at several levels. Everyone however has got it right- TCP is the immediate treatment, if available. The question again when we have said that, as you might guess, is can we try atropine if pacing is not immediately available. Yes, because what you see may not be infranodal block and pacing can be painful to the patient if a slight or modest increase in heart rate can alleviate the symptoms. In the 1997 text and before, Atropine was listed as a Class IIB for these reasons. Must the ACLS course be conducted in the order listed in the instructor manual? Lessons 1-7 should be presented in order. Included in Lessons 17 are such topics as megacode review, technology review, and the airway and CPR/AED cases. The remaining lessons build on these lessons. Students are expected to manage airway and CPR through all remaining stations. These lessons should be presented in order, but there is flexibility in the order of the remaining lessons. 6 15. Admin 16. Science Can the ACLS Renewal course be taught, even though it is a new course and providers will not have been through the new course previously? Yes. The instructor manual contains the renewal lesson plans, and the DVD contains the renewal course videos which may be used now. The guidelines specify that students must hold a current ACLS card in order to take a renewal course. TCs may make exceptions to this policy ONLY if there was no course available for the student, only a short time has lapsed since recommended renewal date on the card, and the TC feels the student made every attempt to renew before expiration date on current card. It appears that there are some inconsistencies in the new guidelines for ACLS. On pages 22- 23 in the ACLS Handbook, it states that if patients in the far right column (Intermediate/Low risk UA), develop intermediate risk criteria, adjunctive treatment with NTG, b blockers, clopidogrel, heparin and GP2b3a inhibitors (Box 10) should be started. But, on pages 39-40 it states that intermediate risk patients get Heparin, but not the clopidogrel or GP 2b3a inhibitors. Which is correct? (From ACLS Subcommittee/editors) First, I always preface algorithm comments such as these by noting that the algorithms, especially ACS, are only general guidelines that are applied by knowledgeable healthcare providers to individual patients. For example, adjunctive therapy is always qualified e.g. "as appropriate", "consider". The algorithms are additionally complicated by the rapidly changing science in ACS. The ACS 2005 guidelines algorithm on page 23 in the handbook is reproduced from the Guidelines document page IV 90. The algorithm on page 40 is an expanded portion of the ACS algorithm imported from the current ACLS Experienced Provider material dealing with patients with unstable angina and NSTEMI and as such cannot be directly compared with the ACS algorithm. So, for example, a patient at low or intermediate risk who develops positive markers should receive GP IIB/IIIA inhibitor therapy (and now clopidogrel) if an invasive strategy is selected. A patient at intermediate risk by ECG criteria can develop intermediate risk clinical or marker criteria (e.g. "gray zone troponins) and then receive heparin and clopidogrel but not GP IIB/IIIA inhibitors (as these are indicated for troponin + patients with an early invasive strategy). Again, the healthcare provider would need to know the background material and be proficient in ACS risk stratification to properly use the algorithm. In summary, the two algorithms are not inconsistent but depend on additional data, information and individual application. I would also emphasize that this information is part of the EXPERIENCED PROVIDER material and is not intended for the basic provider course. EP instructors and students should have this additional expertise. The basic provider is only instructed on the initial 7 treatment strategies, ECG stratification and the STEMI pathway. Even here, additional knowledge is necessary as clopidogrel, for example, would be considered (and now FDA approved) when a fibrinolytic conservative approach is planned. But clopidogrel administration and dose should be deferred to the cardiologist when an invasive approach (primary or rescue PCI) is planned and is contraindicated in shock or preshock patients who may require emergency surgery until coronary anatomy is defined. This is covered in the new ACS video when the ED physician tells the nurse, “and give clopidogrel if requested by the cardiologist". This question is very good because it points out that a simple algorithm can only be used as a guide and not a recipe for these complex clinical situations. 17. Admin 18. Admin 19. Science 20. Admin What do we do with the testing checklists after the course is over? The management of the testing materials has not changed from that discussed in the administration section of the PAM. You are required to keep those testing materials of students who are being remediated, or fail the course. Otherwise, you are only required to keep the roster with students pass/fail status, exam score, etc. A TC may choose to keep the testing checklists for a period of time, but this is not a requirement by AHA. Are students required to complete the rhythm and pharmacology self-assessment modules on the CD prior to attending the course? The expectation is that ALL students will arrive at the ACLS course with adequate knowledge in rhythm identification and pharmcology to be successful in the ACLS course. You’ll want to require the self-assessment module completion of most of your students. However, on an individual basis, if you feel confident that a student knows the material then it is up to the TCC/TCF to make the decision of whether or not the self-assessment must be completed. Some defibrillators take longer to charge than others. Since the goal of CPR is to limit interruptions to less than 10 seconds, what do you do if your defibrillator takes longer than 10 seconds to charge? You’ll note on the ACLS Course DVD, a student states, “…since this defibrillator charges in about 3 seconds, we don’t need to continue CPR”. So, you’ll want to teach your students that if a defibrillator takes longer than 10 seconds to charge, CPR should be continued while the defibrillator is charging. Since many of us library the provider manuals IAW with AHA policy, are the student CDs reusable also? Yes. Students may log onto the self-assessment program as many times as desired. (They will have to alter their name each time, I believe) Multiple student use works fine, each student will log in with their own name. 8 21. Structure There are only 4 scenarios for megacode learning and testing stations. What do we do when there are more than 4 students in each station? You must use the same algorithm sequence with each student. However, you may change the patient’s name, location of arrest, etc. in the scenario, as long as you follow the algorithm sequence. 22. Will there be an EMS version of the ACLS exams? Not at this time. The written exams are generic and test basic ACLS knowledge to include rhythm analysis and pharmacology. The megacode scenarios exist for both pre and in-hospital students. Do we have to adhere to the recommended instructor ratios of 1:6, with 1:3 in the airway and CPR/AED stations? (See question 9 above for ratios in the airway and CPR/AED stations.) For the remainder of the stations, you may teach the class with 1:8. Be aware, this increase in ratio will add 80 minutes to the course for each student over 6 per group. For example: You’ll add 160 minutes to the course is your ratio is 1:8. The sample agenda takes 13.5 hours with breaks. Adding 180 minutes this agenda will take 16.1 hours with breaks. Has AHA given any recommendations regarding the Joule energy setting for synchronized cardioversion of perfusing rhythms such as PSVT, Atrial Flutter, Atrial Fibrillation, ventricular tachycardia using the new biphasic defibrillators? I'll refer you to page IV-42 in 2005 Guidelines for CPR and ECC, section "Supraventricular Tachycardias (Reentry SVT)". In case you don't have this book, here are the important statements in this section that address your question: "Cardioversion with biphasic waveforms is now available, but the optimal doses for cardioversion with biphasic waveforms have not been established with certainty. Extrapolation from published experience with elective cardioversion of atrial fibrillation using rectilinear and truncated exponential waveforms supports an initial dose of 100 J to 120 J with escalation as needed. Until further evidence becomes available, this information can be used to extrapolate biphasic cardioversion to other tachyarrhythmias." Admin 23. Structure 24. Science 9