Caroline Doty
Curriculum Vitae
Department of Radiation Oncology
303 E. Chicago Ave
Ward Building Rm. 13-007
(312)-503-4320
E-mail: caroline-doty@northwestern.edu
Academic Background:
Ph.D. Graduate Student
Integrated Graduate Program
Department of Radiation Oncology
Emphasis in Nanotechnology and Virology
Expected Graduation Date: 2012
Bachelor of Science (B.S.), 2007
Biology Major, Chemistry Minor
Emphasis in Microbiology
Clayton State University
Morrow, Georgia
Cum laude
Teaching Experience:
Graduate Teaching Assistant
Graduate level Virology
Department of Microbiology and Immunology
Northwestern University
Spring 2010
Duties:
 Lecture
 Led organized exam study sessions
 Proctor and grade exams
Guest Instructor
Radiation Oncology
Nuclear Medicine Academy, Northwestern Memorial Hospital
Winter 2010, Winter 2009
Guest Instructor
Pathology
Nuclear Medicine Academy, Northwestern Memorial Hospital
Winter 2010, Spring/Summer 2009
Instructor, Hands on Workshop for Faculty
Production and Photocatalyic determination of ZnS Nanoporous Nanoparticles
2nd Annual Congress of Nanomedicine Theory to Therapy
University of Alexandria, Egypt
August 2010
Supplemental Instructor (SI)
Analytical and Organic Chemistry
Clayton State University
Fall Semester 2005 until Summer Semester 2007
Duties:
 Instructed and helped students learn Analytical and Organic Chemistry
 Lectured on Analytical Chemistry
 Led organized study sessions
 Created activities to actively engage fellow students
 Acted as a role model and mentor for other students
 Proctor Exams
Teaching Assistant
Organic Chemistry
Clayton State University
Fall Semester 2006
Duties:
 Provide laboratory lectures
 Answer laboratory related questions
 Help students with lab/experimental set-up
 Create laboratory final exam
 Grade papers and exams
 Proctor exams
Peer Tutor
Clayton State University
Fall Semester 2005 until Summer Semester 2007
Duties:

Tutored the undergraduate students in the following courses; Biology 1107/1108,
Analytical Chemistry, Organic Chemistry, Biochemistry, Microbiology, Cell biology,
Genetics, Botany, Comparative Vertebrate Anatomy, Advanced Microbiology, and
Advanced Biochemistry.
Undergraduate Research Experience:
Research Internship and Biology Research Practicum
Course requirement for Clayton State University

Worked under Dr. Michelle Furlong
2006-2007


Conducted an independent research project that studied microbial ecology
The project entailed developing novel methods for culturing soil bacteria
Graduate Research Experience:
Gayle Woloschak, Ph. D., Graduate Thesis lab
April 2008- Current
Department of Radiation Oncology
Northwestern University, Chicago IL
 Studying the use of Fe3O4@TiO2 nanoparticles as tools to image tumors
 Studying the use of Fe3O4@TiO2 nanoparticles as tools to cleave viral HPV DNA
 Studying the use of Fe3O4@TiO2 nanoparticles as a therapy for cervical cancer
 Skills acquired/practiced: western blotting, confocal microscopy, mammalian cell
culturing, RT PCR, atomic force microscopy, tissue staining, conjugation of
nanoparticles to DNA, PNA and peptides, and production of nanoparticles.
Hank Seifert, Ph.D., Laboratory Rotation
Jan 2008- April 2008
Department of Microbiology and Immunology
Northwestern University, Chicago IL
 Participated in a study mapping the surface exposed domains of PilQ, a pilus secreating
protein found in Neisseria gonorrhoeae.
 Skills acquired/practiced: MSTL Spin labeling using an EPR spectrophotometer, bacterial
culturing, cloning, site specific mutagenesis, PCR, DNA sequencing, and bacterial
sensitivity assays.
Lou Laimins, Ph. D., Laboratory Rotation
Sept 2007- Dec 2007
Department of Microbiology and Immunology
Northwestern University, Chicago IL
 Participated in a study investigating the genetic domains of Human papillomavirus that
control/contribute to the regulation of Caspase 3,8 and 9 in HPV virally infected
epithelial cells
 Skills acquired/practiced: mammalian cell culturing, viral transfection, production of
primary cell lines from neonate foreskins, and western blotting.
Publications
Doty C, Brown E, Wu A, Paunesku and Woloschak G. Effects of Fluorescent Dye Coating of
Metal Oxide Nanoparticles on DNA Scission. The Journal of the Robert H. Lurie
Comprehensive Cancer Center of Northwestern University. 13.1 (2009): 72-76.
Arora H, Paunesku T, Doty C, Yuan Y, Boyle J, Petras K, Rabatic B, Woloschak G. Titania
nanocomposites. Kumar C, ed. Nanocomposites for Life Sciences. Baton Rouge: Wiley. Print.
Nanomaterials for the Life Sciences ser. (2010)
Thurn T, Arora H, Paunesku T, Wu A, Brown EMB, Doty C, Kremer J, Woloschak GE.
Endocytosis of titanium dioxide nanoparticles in prostate cancer PC-3M cells. Nanomedicine:
Nanotechnology, Biology and medicine. 7.2 (April 2011): 123-130
Presentations and Lectures at Academic Conferences:
Doty C, DNA and cell culturing effects of Fe3O4@TiO2 nanoparticles and nanoconjugates
targeting Human Papillomavirus. Lecture given at: 2nd Annual Congress of Nanomedicine
Theory to Therapy. University of Alexandria, Egypt. 2010 August 3
Doty C, Production and photocatalyic determination of ZnS nanoporous nanoparticles. Hands
on workshop lecture presented at: 2nd Annual Congress of Nanomedicine Theory to Therapy.
University of Alexandria, Egypt. 2010 August 1-2.
Doty C, Wu A, Harden C, Brown E, Paunesku T, Woloschak G. Evaluating the use of
Fe3O4@TiO2 nanoparticles and nanoconjugates as a potential theranostic to target HPV
oncogenes [abstract]. Poster session presented at: Fourth Annual NCI Alliance for
Nanotechnology in Cancer Investigators’ Meeting; 2009 October 20-22; Los Angeles, CA.
Doty C, Wu A, Harden C, Brown E, Paunesku T, Woloschak G. DNA and cell culture effects of
Fe3O4@TiO2 nanoparticles and nanoconjugates targeting Human Papillomavirus genome
[abstract]. Poster session presented at: American Association of Cancer Research 100th General
Meeting; 2009 April 22-24; Denver, CO.
Thurn KT, Paunesku T, Wu A, Brown EMB, Arora H, Doty C, Woloschak GE. Endocytic
mechanisms that govern TiO2 nanoparticle uptake in prostate cancer PC-3M cells [abstract].
Poster session presented at: American Association for the Advancement of Science 175th Annual
Meeting; 2009 February 12-16; Chicago, IL. Washington, DC: AAAS; 2009. p 12.
Brown EMB, Paunesku T, Wu A, Thurn KT, Hatcher T, Doty C, Arora H, Yuan Y, Woloschak
GE. Evaluation of the abilities of peptide nucleic acid-titanium dioxide (PNA-TiO2)
nanoconjugates to induce site-specific DNA damage in vitro and in situ [abstract]. Poster session
presented at: American Association for the Advancement of Science 175th Annual Meeting; 2009
February 12-16; Chicago, IL. Washington, DC: AAAS; 2009. p 12.
Woloschak G, Wu A, Brown EMB, Thurn KT, Doty C, Arora H, Boyle J, Paunesku T.
Radiation-induced nanoparticles for cancer treatment [abstract]. In: Exploring New Avenues in
Tailoring Cancer Treatment, 12th Annual International Alexandria Oncology Conference; 2009
January 13-16; Alexandria, Egypt. Alexandria, Egypt: Alexandria University; p 58.
Doty C, Rivers J, Furlong M. A Novel Method for Culturing Soil Bacteria [abstract]. Poster
session presented at: American Society for Microbiology 107th General Meeting; 2007 June;
Toronto, Canada.
Academic Honors and Awards:
2009-2011
2006-2007
2004-2007
2004-2007
2005-2007
NIH Grant U54CA119341, Research Supplement to Promote Diversity in Health
and Related Research. Grant funds full tuition and stipend reimbursement as
well as lab and travel expenditures.
Senior Chemistry Award for Academic Excellence in Chemical Sciences, Clayton
State University, Morrow, GA
Clayton State University Scholastic Achievement Award, Clayton State
University, Morrow, GA
Deans list Award for Academic Excellence, Clayton State University, Morrow,
GA
Certificate of Appreciation and Excellence as a Supplemental Instructor in
Chemical Sciences, Clayton State University, Morrow, GA
Certifications and Workshops:
Advanced Photon Source User Certification
 Argonne National Laboratory
 Completed facility core training courses January 2009
Supplemental Instruction Supervisor Workshop
 Two day workshop
 Certified as a Supplemental Instruction Peer Leader on Aug 20, 2005
 Training provided through University of Missouri, Kansas City
Serv-safe certification
 Certification of Sanitation in the state of Wisconsin
 Certified on November of 2000
Clubs and Organizations:
Radiation Research Society
Member -2010
Continuing Umbrella of Research Experiences (CURE) mentor for undergraduate students
interested in cancer research
Mentor – 2008/2009/2010/2011
American Association of Cancer Research
Member- 2009-current
Introducing High School Students to Science and the World of Biotechnology
Volunteer Mentor - 2006/2007
Clayton State Science Association
Member - 2004 until 2007
American Society for Microbiology
Member – 2006-current