1. Search strategy, July 2007 Nr 1 Hits Search term 72535022 ME66; EM74; CDSR93; CCTR93; SM78; HG05; PI67; BA70; IS74 2 1558945 NUTRITION OR CT=NUTRITION OR DIET THERAPY OR CT=DIET THERAPY OR FEEDING BEHAVIOR OR CT=FEEDING BEHAVIOR OR DIETARY MANAGEMENT OR CT=DIETARY MANAGEMENT OR NUTRITIONAL MANAGEMENT OR CT=NUTRITIONAL MANAGEMENT OR NUTRITION OR NUTRITIONAL 3 1199244 DIET OR DIETARY OR FEEDING#BEHAVIOR OR CALORIC INTAKE OR LIPID#LOWERING OR LOW ENERGY DIET OR ((FAT OR CALORIC) AND (RESTRICTION OR RESTRICTED OR INTAKE)) 4 835944 EXERCISE MOVEMENT TECHNIQUES OR EXERCISE THERAPY OR PHYSICAL FITNESS OR CT=PHYSICAL FITNESS OR GYMNASTICS OR CT=GYMNASTICS OR ((PHYSICAL EDUCATION AND TRAINING) OR (CT=PHYSICAL EDUCATION AND TRAINING)) OR SPORT# OR CT=SPORTS OR EXERCISE# 5 9780348 WALK OR WALKING OR JOGGING OR ACTIVITY OR ACTIVITIES OR PHYSICAL OR FITNESS OR BICYCLING OR CYCLING OR AEROBIC# OR TRAIN OR TRAINING OR GYMNASTIC# OR CT=EXERCISE MOVEMENT TECHNIQUES OR CT=EXERCISE THERAPY OR (CT=MIND-BODY AND RELAXATION TECHNIQUES) 6 457458 (MIND-BODY AND RELAXATION TECHNIQUES) OR STRESS MANAGEMENT OR RELAXATION OR COPING ABILITY OR COPING SKILLS OR YOGA OR BREATHING EXERCISES OR CT=BREATHING EXERCISES OR MEDITATION OR SELF# MANAGEMENT OR SELF# CARE OR STRESS REDUCTION 7 2265541 2 OR 3 8 10116364 4 OR 5 9 490549 (7 AND 8) OR (7 AND 8 AND 6) 10 300872 LIFESTYLE OR CT=LIFESTYLE/PC OR CT=LIFESTYLE/ED OR LIFESTYLE OR LIFE#STYLE OR LIFE STYLE OR HEALTH PROMOTION OR CT=HEALTH PROMOTION OR BEHAVIOR THERAPY OR CT=BEHAVIOR THERAPY OR HEALTH BEHAVIOR OR CT=HEALTH BEHAVIOR 11 229066 HEALTH EDUCATION OR CT=HEALTH EDUCATION OR COMPLEMENTARY THERAPIES OR CT=COMPLEMENTARY THERAPIES OR HEALTH PROMOTION OR HEALTH EDUCATION OR HEALTH BEHAVIO#R OR RISK FACTOR MODIFICATION 12 13 6758502 MANAGEMENT OR TRAINING OR PROGRAM OR PROGRAMME OR PREVENTION OR PREVENTIVE MEDICINE OR PREVENTION OR PREVENTING OR PREVENT# 13547922 THERAPY OR CHANGE OR CHANGING OR IMPROVEMENT OR IMPROVING OR MODIFICATION# OR MODIFY OR MODIFIES OR MANAGING 14 412590 10 OR 11 15 18023469 12 OR 13 16 284946 14 AND 15 17 880307 DIABETES OR CT=DIABETES OR DIABETES MELLITUS, TYPE 2 OR CT=DIABETES MELLITUS, TYPE 2 OR NIDDM OR IIDM OR DM2 OR NON INSULIN#DEPENDENT OR NON INSULIN# DEPEND 18 352763 CT=DIABETES/PC OR CT=DIABETES/ED OR CORONARY ATHEROSCLEROSIS OR CT=CORONARY ATHEROSCLEROSIS OR CORONARY HEART DISEASE# OR CT=CORONARY HEART DISEASE/PC OR CORONARY DISEASE OR CT=CORONARY DISEASE 19 1382094 ATHEROSCLEROSIS OR CARDIOVASCULAR DISEASE# Nr Hits Search term OR CORONARY ANGIOGRAPHY OR CT=CORONARY ANGIOGRAPHY 20 1380009 OBESITY OR CT=OBESITY OR OVERWEIGHT OR CT=OVERWEIGHT OR OBESE OR ADIPOSITAS OR OVER#WEIGHT OR HYPERTENSION 21 1817930 HYPERTENSION OR ((HIGH OR ELEVATED) AND (BLOOD PRESSURE OR CHOLESTEROL OR BODY#WEIGHT OR BODY MASS INDEX)) OR GLUCOSE INTOLERANCE OR IMPAIRED OR GLUCOSE TOLERANCE OR GLUCOSE TOLERANT OR METABOLIC SYNDROM# OR CT=METABOLIC SYNDROM 22 212154 CT=GLUCOSE INTOLERANCE OR PREDIABETIC STATE OR CT=PREDIABETIC STATE OR PRE#DIABETES OR PRE-DIABETIC OR DYSLIPIDEMIA OR HYPERLIPIDEMIA OR HYPERGLYCEMIA OR HYPERINSULINEMIA 23 2329221 17 OR 18 OR 19 24 2330330 20 OR 21 OR 22 25 4033293 23 OR 24 26 752193 9 OR 16 27 183483 25 AND 26 28 134717 27 AND PPS=HUMAN 29 134717 S=28 30 24 29 AND TECHNOLOGY ASSESSMENT, BIOMEDICAL 31 17 29 AND BIOMEDICAL TECHNOLOGY ASSESSMENT 32 3 29 AND (EVALUATION STUDIES AND TECHNOLOGY) 33 0 29 AND HEALTH CARE, TECHNOLOGY ASSESS? 34 35 36 22 29 AND HEALTH TECHNOLOGY ASSESS? 0 29 AND HEALTH CARE TECHNOLOGY EVALUAT? 0 29 AND HEALTH TECHNOLOGY EVALUAT? 37 24 29 AND BIOMEDICAL, TECHNOLOGY ASSESS? 38 26 29 AND HTA 39 40 41 3 29 AND MEDICAL, TECHNOLOGY ASSESS? 24 29 AND TECHNOLOGY, ASSESS? ? BIOMEDICAL? 0 29 AND TECHNOLOGI?, BEWERT? 42 0 29 AND TECHNOLOGI?, BEURTEIL? 43 59 29 AND EVALUATION #, MEDICAL? 44 45 46 47 7 29 AND EVALUATION #, BIOMEDICAL? 11 29 AND EVALUATION #, HEALTH CARE 144 30 TO 45 134717 S=29 48 213 47 AND REVIEW ARTICLE? 49 114 47 AND REVIEW-ARTICLE 50 15 47 AND REVIEW LITERATURE 51 15 47 AND REVIEW LITERATURE? 52 1022 47 AND SYSTEMATIC REVIEW? 53 54 37 47 AND UEBERSICHTSARBEIT 31512 47 AND REVIEW? 55 2653 47 AND REVIEW?, LITERATUR? 56 1045 47 AND REVIEW?, SYSTEMATIC? 57 5 47 AND REVIEW?, ACADEMIC? 58 37 47 AND ##BERSICHTSARBEIT? 59 60 61 62 31526 48 TO 58 1369 47 AND META-ANALYSIS 184 47 AND META#ANALYSIS 1705 47 AND (METAANALY? OR META ANALY? OR META#ANALY?) Nr Hits Search term 63 1705 60 TO 62 64 32029 59 OR 63 65 66 67 68 134717 S=29 8187 65 AND RANDOMIZED CONTROLLED TRIAL 405 65 AND RCT 9224 65 AND RANDOMIZED CONTROLLED TRIAL? 69 391 65 AND RANDOM ALLOCATION 77 347 65 AND CROSS#OVER STUD? 78 274 65 AND CROSSOVER PROCEDURE? 79 495 65 AND RCT? 80 9962 65 AND RANDOMI%ED? ? CONTROLLED? ? TRIAL? 81 3382 65 AND RANDOMI%ED? ? CONTROLLED? ? STUD? 82 2254 65 AND RANDOMI%ED? ? CLINICAL? ? TRIAL? 83 842 65 AND RANDOMI%ED? ? CLINICAL? ? STUD? 84 5925 65 AND RANDOMI%ED? ? STUD? 85 11634 65 AND RANDOMI%ED? ? TRIAL? 86 87 88 102 595 65 AND RANDOMISIERT? ? STUDIE? 1 65 AND RANDOMISIERT? ? VERSUCH? 1004 65 AND RANDOM? ?, ALLOCAT? 2 65 AND ZUFALL? 103 1216 65 AND CROSS#OVER? 104 723 65 AND CROSS OVER? 105 106 107 108 146 147 148 149 150 151 152 153 154 155 156 0 65 AND UEBERKREUZ? 5466 65 AND PLA#EBO? 247 65 AND MASK? 16816 66 TO 107 134717 S=29 4720 146 AND ECONOMICS 757 146 AND (ÖKONOMIE OR OEKONOMIE) 1040 146 AND SOCIOECONOMICS 16 146 AND MODELS, ECONOMIC 445 146 AND ECONOMIC ASPECT 7 146 AND ECONOMICS, MEDICAL 183 146 AND HEALTH ECONOMICS 6352 146 AND COST? 527 146 AND KOSTEN? 949 146 AND EFFICIENCY? 157 5352 146 AND EFFECTIVENESS 158 7773 146 AND EFFICACY? 159 32 146 AND EFFIZIENZ 160 145 146 AND COST ANALYSIS 161 916 146 AND EC 162 5 146 AND ECON 163 4720 146 AND ECONOMICS 164 7843 146 AND (ECONOMI? OR OEKONOMI?) 165 1 146 AND GESUNDHEITSOEKONOMIE 166 959 146 AND EFFICIENC? 167 7828 146 AND EFFICAC### 168 169 170 171 172 32 146 AND EFFIZIENZ## 136 146 AND ECONOMIC EVALUATION? 76 146 AND HEALTH CARE FINANCING? 1370 146 AND COST?, ? BENEFIT? AND (STUD? OR TRIAL? OR RATIO? OR ANALYSIS) 72 146 AND (COST?, ? UTILIT? AND (STUD? OR TRIAL? OR Nr Hits Search term RATIO? OR ANALYSIS?)) 173 1494 146 AND (COST?, ? EFFECTIVENESS? AND (STUD? OR TRIAL? OR RATIO? OR ANALYSIS?)) 174 499 146 AND (COST?, ? EVALUATION? AND (STUD? OR TRIAL? OR RATIO? OR ANALYSIS?)) 175 81 146 AND (COST?, ? EFFICIENC? AND (STUD? OR TRIAL? OR RATIO? OR ANALYSIS?)) 176 592 146 AND COST?, ? EFFICAC? AND (STUD? OR TRIAL? OR RATIO? OR ANALYSIS?) 177 2038 146 AND (COST?, ? CONTROL? AND (STUD? OR TRIAL? OR RATIO? OR ANALYSIS?)) 178 18 146 AND (COST?, ? MINIMI#ATION? AND (STUD? OR TRIAL? OR RATIO? OR ANALYSIS?)) 179 351 146 AND (COST?, ? ILLNESS? AND (STUD? OR TRIAL? OR RATIO? OR ANALYSIS?)) 180 1647 146 AND (COST?, ? ANALYS? AND (STUD? OR TRIAL?)) 181 300 146 AND (KOSTEN?, ? NUTZEN? AND (STUDIE? OR ANALYSE?)) 182 300 146 AND (KOSTEN?, ? NUTZEN? AND (STUDIE? OR ANALYSE?)) 183 0 146 AND (KOSTEN?, ? WIRKSAMKEIT? AND (STUDIE? OR ANALYSE?)) 184 3 146 AND (KOSTEN?, ? EFFEKTIVIT? AND (STUDIE? OR ANALYSE?)) 185 2 146 AND (KOSTEN?, ? EFFIZIENZ? AND (STUDIE? OR ANALYSE?)) 186 187 *** TAB Ende *** 117 146 AND (KOSTEN? ? ANALYSE?) AND STUDIE? 23404 147 TO 186 2. Simplified search strategy for update searches, April 2008 and March 2009, PubMed (lifestyle OR life*style OR ((diet OR nutrition) AND (exercise OR activity))) AND (heart OR coronary OR diabetes) AND prevention Limits: Humans, Randomized Controlled Trials or systematic reviews published within the last 1.5 years 3. Search strategy for update search in January 2010, PubMed ("2009"[Publication Date] : "3000"[Publication Date]) AND (((lifestyle OR life*style) AND (intervention)) OR ((diet OR nutrition OR eating OR food*consumption) AND (exercise OR activity OR activities OR movement) AND (relaxation OR meditation OR yoga OR breathing OR mind*body OR autogenic)) AND (heart OR coronary OR diabetes) AND prevention) Limits: Humans, Randomized Controlled Trials