"ANALYTICAL CHALLENGES AND SOLUTIONS FOR DIFFICULT PHARMACEUTICAL
MOLECULES"
NOVEMBER 10TH & 11TH 2015 AT GSK WARE HERTS
TIMETABLED VERSION
The Chromatographic Society is an internationally connected organisation and UK
registered scientific charity devoted to the promotion and dissemination of knowledge on
all aspects of chromatography and related separation techniques.
This Symposium will focus its attention on addressing problems in the following areas:
Separation, Detection, Resolution, Quantification, Identification, Limits of Detection,
Interferences and Structural Elucidation.
Case histories of difficult analyses and solutions to these issues will be presented and
discussed by both in-house GSK analysts and invited external speakers from the
pharmaceutical industry. Experiences in problem solving customers’ difficult analyses will
be presented by instrument companies who will provide insight into their capabilities and
application of their instrumentation and methodologies.
Our Special Guest Speakers will include:
Max Robinson/Alan Hill
GSK
Quantitative Challenges of Charged Aerosol Detection
Dave Elder
GSK
Strategic Approaches to Analysing Mutagenic Impurities
Claire Haylock
GSK
Analysing Mutagenic Impurities: A case study
Rachel Orr
GSK
Challenges inherent in analysing Oligonucleotides
Kris Pearson
GSK
Development and Optimisation of an HPLC method for related impurities for a co-blended
inhaled product
Chris Welch
Merck
Separation of isomeric impurities
Dorina Kotoni
Novartis Pharma AG,
Universal detection in the pharmaceutical industry, an evaluation of recent aerosol-based
detectors for impurity profiling in analytical R&D in RP-HPLC and HILIC
Mark Taylor
Pfizer
Contaminant peaks: sources and solutions for improved performance in gradient LC
Saritha R. Shetty
SPP School of Pharmacy and Technology Management, Mumbai.
High Performance Liquid Chromatography Method Development and Validation for
Simultaneous Estimation of Ofloxacin and Mometasone furoate in ophthalmic solutions
Pauline Phillips
Syngenta
Multidimensional techniques for the Characterisation of polymeric material
REGISTRATION COSTS
Members of either The Chromatographic Society, Royal Society of Chemistry or BMSS £150
Non Members £180
Students* and Retirees £75
NOTE: VAT at 20% is additionally charged on all prices
REGISTRATION WEB LINKS
Please use the appropriate link below to register your intention to attend the symposium.
Exhibiting company’s staff delegates who have free complimentary places as part of their exhibition costs
should also register
Paying delegates use –
https://www.eventspro.net/mm/getdemo.ei?id=1070310&s=_SNCAOGCOR
ChromSoc Committee members and Complimentary Delegates use –
https://www.eventspro.net/mm/getdemo.ei?id=1070310&s=_7EK7ZZL47
*ChromSoc Student Bursaries are available for this event.
The Bursary scheme will target young or less experienced chromatographers /separation scientists.
A maximum of £250 will be awarded per candidate
Details of how to apply are on the Chromsoc Website www.chromsoc.com
SPONSORSHIP, LECTURE CONTENT & EXHIBITION STAND ENQUIRIES
Contacts: Dr. Chris Bevan on chris.anne.bevan@gmail.com &/or
For general queries and assistance: Email: carol@meetingmakers.co.uk
Meeting Makers
Block 4, Unit 4, Kelvin Campus
West of Scotland Science Park
2317 Maryhill Road, Glasgow, G20 0SP
Tel: +44 (0) 141 945 6880
Fax: +44 (0) 141 945 6899
WEB: http://www.meetingmakers.co.uk
Update announcements will be on The Chromatographic Society Website http://www.chromsoc.com/
Table top exhibitors will be integrated into the symposium and invited to present the science and
technology behind their analytical instruments and consumable products.
SPONSORSHIP AND EXHIBITION COSTS
GOLD LEVEL SPONSORSHIP £1750

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Table top exhibition stand & 20 mins lecture time integrated into the programme
3 free delegate admission places
SILVER LEVEL SPONSORSHIP £1250
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Table top exhibition stand & 10 mins lecture time integrated into the programme
2 free delegate admission places
BRONZE LEVEL SPONSORSHIP £750
 Table top exhibition stand and 1 free delegate admission place
Venue address:
GlaxoSmithKline David Jack Centre R&D Ware. Park Road, Ware, Herts, SG12 ODPUK
Exhibitors should send their exhibits marked for the attention of Dr. David Elder at GSK Ware.
Local hotels that are convenient to the GSK site include the Marriot at Cheshunt where committee will be staying.
This symposium forms part of GSK’s 300th anniversary. The original company (Silvanus Bevan) was founded
in 1715 at the Plough Court Pharmacy in the East End of London (see attached picture). After many
mergers and takeovers the genesis of the present company occurred with the merger of SmithKline French
and Beecham in 1990, and five years later with the merger of the Glaxo Group and the Wellcome
Foundation. The present company was founded in 2000 with the merger of SmithKline Beecham and
GlaxoWellcome to form GSK.
1715 to 2015
Plough Court Pharmacy established
Plough Court pharmacy is established, the forerunner of Allen and Hanburys, in London by Silvanus Bevan.
The A&H name continues today.
"ANALYTICAL CHALLENGES AND SOLUTIONS FOR DIFFICULT PHARMACEUTICAL
MOLECULES"
NOVEMBER 10TH & 11TH 2015 AT GSK WARE HERTS
AGENDA TIMETABLE
NOVEMBER 10TH 2015
Exhibitors set up table top exhibits in GSK Ware conference centre from 10 am on November 10 th 2015
Registration of delegates from 12 noon on November 10th 2015
Buffet lunch from 12:45 to 2:00pm with access to exhibits & posters
2:00 to 2:10pm Symposium opens:
Introduction and welcome from The Chromatographic Society, Chris Bevan
Welcome to GSK and safety directions, David Elder
2:10 to 2:30pm Tim Steel Agilent Technologies UK
Title to be announced
2:30 to 2:50pm Sue Roach ANATUNE
Title to be announced
2:50 to 3:35pm Mark Taylor
Pfizer
Contaminant peaks: sources and solutions for improved performance in gradient LC
3:35 to 4:20pm Pauline Phillips Syngenta
Multidimensional techniques for the Characterisation of polymeric material
4:20 to 4:40PM Presentation by Chris Message (Title to be announced)
4:40 to 5:20pm Saritha Shetty SPP School of Pharmacy and Technology Management, Mumbai.
High Performance Liquid Chromatography Method Development and Validation for Simultaneous
Estimation of Ofloxacin and Mometasone furoate in ophthalmic solutions
5:20 TO 6:00pm Andy Rice
From the Plough Court Pharmacy to GSK, Ware: 300 years of Quality and Innovation
Symposium day 1 science sessions close.
Delegates transfer to GSK Ware social club for evening meal and pub style quiz chaired by Dave Rudd
starting at 6:30pm
NOVEMBER 11TH 2015
9:00 to 9:10am GSK introduction and safety instructions David Elder
9:10 to 9:40am James Heaton University of West of England
Practical evaluations of hydrophilic interaction chromatography for pharmaceutical analysis
9:40 to 10:00am Presentation by Steve Preece
Title to be announced
10:00 to 10:45am Max Robinson/Alan Hill
GSK
Quantitative Challenges of Charged Aerosol Detection
10:45 to 11:30am Dorina Kotoni
Novartis Pharma AG,
Universal detection in the pharmaceutical industry, an evaluation of recent aerosol-based detectors for
impurity profiling in analytical R&D in RP-HPLC and HILIC
11:30 to 12:15 Kris Pearson
GSK
Development and Optimisation of an HPLC method for related impurities for a co-blended inhaled product
12:15 to 1:00pm Chris Welch
Separation of isomeric impurities
Merck
1:00 to 2:00pm LUNCH, EXHIBITION & POSTER COURT OPENS
2:00 to 2:45pm Claire Haylock
Analysing Mutagenic Impurities: A case study
GSK
2:45 to 3:30pm Dave Elder
GSK
Strategic Approaches to Analysing Mutagenic Impurities
3:30 to 4:15pm
Rachel Orr
GSK
Challenges inherent in analysing Oligonucleotides
4:15 TO 4:35pm
Stuart Phillips (title to be announced)
4:35 to 4:55pm Jim Thorne
CESI-MS A new way to Analyze for PACAP and VIP
5:00pm Round up summary of the symposium.
Symposium closes and farewell
Posters:
Unification of charge heterogeneity, purity, and molecular weight analyses of mAbs into a single analysis
using CESI-MS
Jim Thorne
D. Sindu Priya Student poster Title to be announced
Exhibitors
Scientific and Technical Presenters currently include the following sponsoring exhibitors:
Hichrom Limited
Experts in
Chromatography
THAMES RESTEK