For PRC use only Date of approval: Signature of Chair: Siemens Vision 1.5T Sequence Description Sequence name: DTI v2.0, 2.1, 2.2, 2.3, and 2.4 – diffusion tensor imaging sequences Developer: Jan Hrabe, NKI Date: 5/4/2001 Filenames: Location: /usr/appl/sequence/local dti_v20.ekc dti_v21.ekc dti_v22.ekc dti_v23.ekc dti_v24.ekc Other files: SPL source code file dti_v11.sph in the $EXT/local directory. Brief description: These sequences are based on the approved DTI sequences dti_v14.ekc and dti_v15.ekc, the main characteristics are as follows: 1. dti_v20.ekc: up to 27 slices with reduced slice thickness of up to 2.5 mm (uses longer ramp times), acquisition matrix 96 x 128, TE 100ms, max gradient 20.9 mT/m, 6+1 b values (1000 s/mm2) in directions based on Jones DK, Horsfield MA, Simmons A: Optimal Strategies for Measuring Diffusion in Anisotropic Systems by Magnetic Resonance Imaging (MRM 42:515-525, 1999), page 518. Slice profiles are identical to those in sequences dti_v1X.ekc. 2. dti_v21.ekc: identical to v20 except 8+1 b values are used and only 19 slices can be acquired. 3. dti_v22.ekc: intended for isotropic acquisition, minimum voxel size 2.5 mm, matrix 128 x 128, TE 100 ms, 6+1 b values, 27 slices, EPI BW increased to maximum possible (0.6 ms per line), max. diffusion gradient 20.856 mT/m, b = 1000 s/mm2. 4. dti_v23.ekc: identical to dti_v22.ekc except 8+1 b values are used and only 20 slices can be acquired. 5. dti_v24.ekc: DTI sequence with TE reduced to 82.92 ms to increase SNR. 27 (matrix 128 x 128) slices can be acquired with 2.5 mm cubic voxels but only in the principal orientations (no oblique slices). 6+1 b values (1000 s/mm2) are acquired in directions that always combine 2 gradients (as in the dti_v13.ekc). The directions are: (0,0,0), (1,1,0), (1,0,1), (0,1,1), (1,-1,0), (-1,0,1), (0,1,-1) for (phase, read, slice).