CONTINUING REVIEW OF A PROTOCOL FOR USE OF ANIMALS IN RESEARCH OR TEACHING IUPUI School of Science Institutional Animal Care and Use Committee (IACUC) Submit to: IACUC, c/o School of Science, LD 222, 402 N. Blackford Street, Indianapolis, IN 46202-3276 Principal Investigator (P.I.): Protocol #: Title: Protocol origination date Approved Species: Approved Total Amendment dates: Attach any additional information for each question on a separate document if needed 1. Have any significant changes been made since the last protocol review or amendment: ____No ____Yes (if yes, submit an amendment form with this continuing review) 2. Number of animals purchased or weaned since last review (indicate genus): ___________________________________________________________________ Number of animals purchased or weaned since project origination (indicate genus): ___________________________________________________________ 3. Names of all personnel involved in this project since last review (indicate new personnel) University policy on Anesthetic Gas Safety requires researchers and staff to complete an on-line training course before using anesthetic gases http://ehs.iupui.edu/training.asp?content=anesthetic-gas-safety P.I.__________________________________ ___________________________________ ____________________________________ _______________________________________ _______________________________________ _______________________________________ 4. Describe problems or concerns encountered, especially problems of animal pain or distress: Was the attending veterinarian consulted and if not, why? ____N/A ____Yes 5. [4-A] Have alternatives to this use of animals [4-B] and to procedures involving more than momentary pain or distress appeared since protocol approval? ___No ___Yes (if yes, justify continued animal use) Specify sources consulted; for databases, give keywords (for alternatives and procedures), years searched (>=10 years), and date of search (“alternative” or equivalent must be a keyword) 6. What is the funding and status of this project? Submitted agency and title: _____________________________________________________ Source of funds and title: ________________________________________________________ Not initiated (anticipated initiation date: ) Will not be initiated* Check if ONGOING Completed* *Automatically terminated if selected Principal Investigator ____________________________________________ Date OFFICE USE ONLY: Final Expiration Date: Three years from Protocol origination date APPROVED DISAPPROVED TERMINATED SOS IACUC Signature: Date: Attending Veterinarian Signature Date SOM IACUC Signature Date Continuing Review of a Protocol Version 7/23/14-ckk