NFSC 440 - ADVANCED HUMAN NUTRITION
Fall 2005
Instructor: Katie Silliman, Ph.D., R.D.
Office: Holt Hall 104
Phone: 898-6245
Office Hours: Tuesday 2 – 4 PM, Wednesday 1-2 PM, Thursday 2 - 4 PM or by appointment
Prerequisites: NFSC 240 and Chem 350 or Chem 451
E-mail: ksilliman@csuchico.edu
Texts:
Advanced Nutrition and Human Metabolism, 4th ed., by Gropper, Smith + Groff (REQUIRED)
Supplemental Reader available at Mr. Kopy (REQUIRED) – ask for packet #82
WEB SITE: http://www.nap.edu/ - this web site will allow you to read the DRI reports, just type “dietary
reference intake” in the search window.
Recommended References:
1. A biochemistry textbook
2. A medical physiology textbook
3. For those needing to review biochemistry check out the WEB SITE:
http://web.indstate.edu/thcme/mwking/home.html.
Grading:
3 exams -----------------------------Final (comprehensive) -------------Internet Product Ad or Article ------Outline of product ------------------Critique of claims
made for supplement/CAM --------
300 points
150
10
20
100
-----------580 points
Assignments are due at the beginning of class. Assignments turned in late will have 5 % of the points deducted for EACH day late.
OBJECTIVES:
 To provide detailed information on the structure, function, digestion, transport, storage, and metabolism of
the nutrients.
 To delineate key metabolic pathways in the utilization of macronutrients as well as the interrelationships
among nutrients in metabolism.
 To have a basic understanding of the physiology of exercise.
 To identify nutritional requirements (energy and nutrients) and significant food sources of macro- and
micro-nutrients.
 To interpret the basis of human nutrient deficiencies and excesses.
 To demonstrate comprehension and interpretation of nutrition-related research as reported in scientific
publications. This will be accomplished by classroom discussion of a research article and the completion of
a written critique of claims made for alternative nutrition and herbal therapies.
 To provide a basis for evaluation of current and recommended nutritional practices.
 To become familiar with complementary and alternative nutrition, herbal therapies, and dietary supplements.
 To become familiar with the role genetics plays in nutrition.
 To develop interpersonal communication skills and to learn to work effectively as a team member by doing
collaborative work.
 To become proficient at gathering information using current information technologies.
TENTATIVE COURSE SCHEDULE
WEEK
TOPIC
READINGS
1
Overview of the cell
Strategy of metabolic oxidation; ATP
regeneration (riboflavin, niacin)
1-21; 53-69;
281-290
2
Carbohydrates
Carbohydrate metabolism and Intermediary
metabolism (pantothenic acid, biotin)
Fuel use during exercise
72-101;
291-301;
243-250;
257-258
3
Fiber (Take home quiz)
108-120
4
Lipids
Lipoproteins and cholesterol
EXAM I - THURS. SEPT. 15th
128-162
5
Lipids (Cont.)
Oxidation and synthesis (thiamin)
Product AD or Article Due - THURS. SEPT. 22nd
275-281
6
Diet and Heart Disease
147-151;166-167
7
Protein and amino acids
Protein metabolism (B-6)
Nutrigenomics
172-218;
316-321;
168-171;322-324
8
Protein quality and requirements
Interpreting nutrition research
EXAM II - THURS. OCT. 13th
218-223; 551-565
9
Integration and regulation of metabolism
230-243; 226-229
10
Etiology of Obesity
Alcohol metabolism
Outline of Product and References Due TUES. OCT. 25th
11
Water-soluble vitamins (C, folic acid, B-12)
260-273; 301-315
12
Fat-soluble vitamins
EXAM III - THURS. NOV. 10th
325-367
13
Fat-soluble vitamins (cont.)
14
Minerals
Critique Due - THURS. DEC. 1st
(oral presentations - THURS)
70-71; 161-165; 520-522;
101-105
378-407
15
Minerals – cont.
(oral presentations - TUES)
FINAL EXAM TUES. DEC. 13th from 2-3:50 pm
417-484