Consejo Nacional de Ciencia y Tecnología Directorio de Científicos y Tecnólogos Peruanos Noviembre del 2001 CURRÍCULO RESUMIDO COORDENADAS Nombre: Año de nacimiento: Dirección postal: Dirección electrónica: Héctor H. García Lescano 1963 Av. San Borja Norte 834-601 hgarcia@terra.com.pe hhgar@hotmail.com Página web: Teléfonos: 51 1 224 2871 / 51 1 975 2111 (casa) 51 1 328 7360 (oficina) Facsímiles: 51 1 328 7382 (I.C.N) Institución actual: Universidad Peruana Cayetano Heredia / Instituto de Ciencias Neurológicas Especialidad Científica o Tecnológica: Salud Pública / Parasitología Grado más alto obtenido (indicar institución y año): PhD. Johns Hopkins University, 2002 COLABORADORES MÁS FRECUENTES Nombres: Robert H. Gilman, MD,DTMH Armando E. Gonzalez, DVM, PhD Oscar H. Del Brutto PUBLICACIONES EN REVISTAS ARBITRADAS (en orden directo o regresivo, añadir páginas si es necesario, omitir ponencias en eventos) 1. García HH, Martinez M; Gilman RH, Herrera G, Tsang VCW, Pilcher JB, Diaz F, Verastegui M; Gallo C, Porras M; Alvarado M; Naranjo J, Miranda E, and the Cysticercosis Working Group in Perú: “Diagnosis of cysticercosis in endemic regions”. Lancet 338: 549-51, 1991. 2. Diaz JF, Verastegui M, Gilman RH, Tsang VCW Pilcher JB, Gallo C, García HH, Torres P, Montenegro T Miranda E, and the Cysticercosis Working Group in Perú (CWG). “Immunodiagnosis of human cysticercosis (Taenia solium): a field comparison of an antibody-enzyme-linked immunosorbent assay (ELISA), an antigen-ELISA, and an Enzyme-linked Immunoelectrotransfer Blot (EITB) assay in Peru.” American Journal of Tropical Medicine and Hygiene 46: 610-15, 1992. 3. Diaz F, García HH, Gllman RH, Gonzales AE, Castro M; Tsang VCW Pilcher JB, Vasquez LE, Lescano M, Carcamo C, Madico G, Miranda E, and the Cysticercosis Working Group in Perú: “Epidemiology of Teniasís and Cysticercosis in a Peruvian Village.” American Journal of Epidemiology 135: 875-82, 1992 4. Hamaker BR, Valles C, Gllman R, Hardmeier RM, Clark D, Garcia HH, Gonzales AE, Kohlstad I, Castro M, Valdivia R, Rodríguez T, Lescano M: “Amino acid and fatty acid profiles of the Inca Peanut (Plukenetía volubilis).”, Cereal Chemistry, 69 (4): 461-63, 1992. 5. Moro PL, Gilman RH, Wilson M, Schantz PM, Verastegui M, García HH, Miranda E: “Immunoblot (Western blot) and double diffusion (DD5) tests for hydatid disease crossreact with sera from patients with cysticercosis”, Transactions of the Royal Society of Tropical Medicine and Hygiene, 86: 422-423, 1992. 6. García HH, Gilman R, Martinez M, Tsang VCW, Pilcher JB, Herrera G, Diaz F, Porras M, Alvarado M, Orrillo E, Torres P, Miranda E, and the Cysticercosis Workíng Group in Peru (CWG): “Cysticercosis as a major cause of epilepsy in Peru.”, Lancet, 341: 197-200, 1993 6. García HH, Herrera G, Gilman RH, Tsang VCW Pilcher JB, Diaz F, Candy EJ, Miranda E and J Naranjo-Cysticercosis Workíng Group in Peru. “Discrepancies between cerebral computed tomography and western blot in the diagnosis of neurocysticercosis.” American Journal of Tropical Medicine and Hygiene 50:152-157, 1994 7. Moro PL, Guevara A, Verastegui M; Gilman RH, Poma H, Tapia B, Tsang VCW García HH, Pacheco R, Lapel C, Miranda E, The Cysticercosis Working Group in Perú (CWG): “Distribution of hydatidosis and cysticercosis in different Peruvian populations as demonstrated by an enzyme-linked immunoelectrotransfer blot (EITB) assay.” American Journal of Tropical Medicine and Hygiene 51: 851-855, 1994. 6. Gonzalez AE, Gilman R, Garcia HH, McDonald J, Kacena K, Tsang VCW, Pilcher JB, Suarez F, Gavidia C, Miranda E, the Cysticercosis Working Group in Perú (CWG): “Use of sentinel pigs to monitor environmental Taenia solium contamination.” American Journal of Tropical Medicine and Hygiene 51 (6): 847-50, 1994 7. Garcia HH, Gilman RH, Tovar M, Flores E, Jo R, Tsang VCW Diaz F, Torres P, Miranda E, the Cysticercosis Working Group in Perú (CWG): “Factors Associated with T. solium Cysticercosis. Analysis on 946 Peruvian Neurologic Patients.”, American Journal of Tropical Medicine and Hygiene, 52 (2)147-50, 1995. 8. Gonzales AE, Garcia HH, Gllman RH, Lopez MT Gavidia C, McDonald J, Pilcher JB, Tsang VCW: “Treatment of Porcine Cysticercosis with Albendazole.”, American Journal of Tropical Medicine and Hygiene, 53: 571-4, 1995 9. Gonzales AE, Garcia HH, Gilman RH, Gavidia C, Tsang VCW, Bernal T, Falcon N, Romero M, Lopez-Urbina MT: “Effective, Single Dose Treatment of Porcine Cysticercosis with Oxfendazole.”, American Journal of Tropical Medicine and Hygiene, 54: 391-4, 1996 10. Evans CAW Gonzalez AE, Gllman RH, Verastegui M, Garcia HH, Chavera A, Tsang VCW, Pilcher JB, The Cysticercosis Working Group in Perú: “Immunotherapy for Porcine Cysticercosis: Implications for prevention of human disease.”, American Journal of Tropical Medicine and Hygiene, 56: 33-7, 1997. 11. Garcia HH, Gilman RH, Catacora M, Verastegui M, Gonzalez AE, Tsang VCW, and The Cysticercosis Working Group in Peru. “Serological Evolution of Neurocysticercosis Patients after Antiparasitic Therapy”, Journal of Infectious Diseases, 175: 486-9, 1997. 12. Evans C, Gilman RH, Garcia HH, Friedland JS: “Controversies in the Management of Cysticercosis”, Emerging Infectious Diseases, 3: 403-5, 1997. 13. García HH, Gilman RH, Tsang VCW, Gonzalez AE, and The Cysticercosis Working Group in Peru. “Clinical significance of neurocysticercosis in endemic villages”, Transactions of the Royal Society of Tropical Medicine and Hygiene, 91: 176-8, 1997. 14. Gonzalez AE, Falcon N, Gavidia C, Garcia HH, Tsang VCW, Bernal T, Romero M, Gilman RH: “Treatment of Swine Cysticercosis with Oxfendazole: A Dose-response Trial.” Veterinary Record, 141: 420-2, 1997. 15. Gonzalez AE, Falcon N, Gavidia C, Garcia HH, Tsang VCW, Bernal T, Romero M, Gilman RH: “Time-response curve of oxfendazole in the treatment of swine cysticercosis.”, American Journal of Tropical Medicine and Hygiene, 59: 832-6, 1998. 16. Garcia HH, Araoz R, Gilman RH, Valdez J, Gonzales AE, Gavidia C, Bravo ML, Tsang VCW, The Cysticercosis Working Group in Peru. “Increased risk for cysticercosis and taeniasis among professional fried pork venders and the general population of a village in the peruvian highlands” American Journal of Tropical Medicine and Hygiene 59: 902-5, 1998. 17. Garcia HH, Harrison LJS, Parkhouse RME, Montenegro T, Martinez SM, Tsang VCW, Gilman RH, and The Cysticercosis Working Group in Peru: “Application of a specific antigen detection ELISA to the diagnosis of human neurocysticercosis“ Transactions of the Royal Society of Tropical Medicine and Hygiene, 92: 411-4, 1998. 18. Evans CAW, Garcia HH, Hartnell A, Gilman RH, Jose P, Martinez M, Remick DG, Williams TJ, Friedland JS: “Elevated concentrations of Eotaxin and Interleukin-5 in human neurocysticercosis”, Infection and Immunity, 66: 4522-5, 1998. 19. Palacio LG, Jimenez I, Garcia HH, Jimenez ME, Sanchez JL, Noh J, Ahn L, Mora O, Giraldo M, Tsang VCW, and The Neuroepidemiological Research Group of Antioquia: “Neurocysticercosis in epileptic persons in Medellín, Colombia.” Epilepsia, 39: 13349, 1998. 20. Wilkins PP, Allan JC, Verastegui M, Acosta M, Eason AG, Garcia HH, Gonzales AE, Gilman RH, Tsanq VCW: “Development of a serologic assay to detect Taenia sollum taeniasis”, American Journal of Tropical Medicine and Hygiene, 60:199-204, 1999. 21. Moro PL, Checkley W, Gilman RH, Lescano G, Bonilla JJ, Silva B, Garcia HH: “Gallstone disease in high-altitude Peruvian rural populations”, American Journal of Gastroenterology, 94: 153-8, 1999. 22. Bern C, Garcia HH, Evans C, Gonzalez AE, Verastegui M, Tsang VCW, Gilman RH: “Magnitude of the disease burden from neurocysticercosis in a developing country”, Clinical Infectious Diseases, 29:1203-1209, 1999. 23. Garcia HH, Talley A, Gilman RH, Zorrilla L, Pretell J, and The Cysticercosis Working Group in Perú: “Epilepsy and neurocysticercosis in a village in Huaraz, Perú”, Clinical Neurology and Neurosurgery, 101: 225-8, 1999. 24. Garcia HH, Gilman RH, Gonzalez AE, Pacheco R, Verastegui M, Tsang VCW, and The Cysticercosis Working Group in Peru: “Human and Porcine T. solium Infection in a Village in the Highlands of Cusco, Peru”, Acta Tropica, 73: 31-36, 1999. 25. Gonzalez AE, Verastegui M, Noh JC, Gavidia C, Falcon N, Bernal T, Garcia HH, Tsang VCW, Gilman RH, Wilkins PP, and the Cysticercosis Working Group in Peru: “Persistence of passively transferred antibodies in porcine Taenia solium cysticercosis”, Veterinary Parasitology, 86: 113-8, 1999. 26. Garcia HH, Gonzalez AE, Gilman RH, Palacios LG, Jimenez I, Rodriguez S, Verastegui M, Willkins P, Tsang VCW, The Cysticercosis Working Group in Perú: “Transient antibody response in Taenia solium infection in fleld conditions A major contributor to high seroprevalence.” American Journal of Tropical Medicine and Hygiene 2000 (in press). 27. Gilman RH, Del Brutto OH, García HH, Martínez M, and The Cysticercosis Working Group in Perú: “Prevalence of taeniosis among neurocysticercosis patients is related to the severity of cerebral infection”, Neurology, 55: 1062, 2000. 28. Garcia HH, Parkhouse RME, Gilman RH, Montenegro T, Bernal T, Martinez SM, Gonzalez AE, Tsang VCW, Harrison LJS, and The Cysticercosis Working Group in Peru: “Serum antigen detection in the diagnosis, treatment, and follow-up of neurocysticercosis patients”, Transactions of the Royal Society of Tropical Medicine and Hygiene, 9, 2000. 29. Pretell EJ, Garcia HH, Custodio N, Padilla C, Alvarado M, Gilman RH, Martinez M, and The Cysticercosis Working Group in Peru: “Short regimen of praziquantel in the treatment of single brain enhancing lesions”, Clinical Neurology and Neurosurgery, 102: 215-8, 2000. 30. Del Brutto OH, Dolezal M, Castillo PR, Garcia HH: “Neurocysticercosis and oncogenesis”, Archives of Medical Research, 31: 151-5, 2000. 31. Verastegui M, Gonzalez AE, Gilman R, Gavidia C, Falcon N, Bernal T, Garcia HH, and The Cysticercosis Working Group in Peru: “Experimental infection model for Taenia solium cysticercosis in swine”, Veterinary Parasitology, 94: 33-44, 2000. 32. Mayta H, Talley A, Gilman RH, Jimenez J, Verastegui M, Ruiz M, Garcia HH, Gonzalez AE: “Differentiating human tapeworm infections by simple H-E staining and Polymerase Chain Reaction-Restriction Enzyme Analysis”, Journal of Clinical Microbiology, 38: 133-7, 2000. 33. Pretell EJ, Garcia HH, Gilman RH, Saavedra H, Martinez M: “Failure of one-day praziquantel treatment in patients with multiple neurocysticercosis lesions”, Clinical Neurology and Neurosurgery, 103(3): 175-177, 2001. 34. Gonzalez AE, Gavidia C, Falcon N, Bernal T, Verastegui M, García HH, Gilman RH, Tsang VCW, and The Cysticercosis Working Group in Peru: “Protection of pigs with cysticercosis from further infections after treatment with oxfendazole”, American Journal of Tropical Medicine and Hygiene, 65: 15-18, 2001. 35. Del Brutto OH, Rajshekhar V, White AC, Tsang VCW, Nash TE, Takayanagui OM, Schantz PM, Evans CAW, Flisser A, Correa D, Botero D, Allan JC, Sarti E, Gonzalez AE, Gilman RH, García HH: “Proposed diagnostic criteria for neurocysticercosis”, Neurology 2001; 57: 177-83. 36. Nash TE, Pretell J, Garcia HH. Nash TE, Pretell J, Garcia HH: “Calcified cysticerci provoke perilesional edema and seizures”, Clinical Infectious Diseases 2001; 33: 1649-53. 37. Hancock K, Broughel DE, Moura INS, Khan A, Pieniazek NJ, Gonzalez AE, Garcia HH, Gilman RH, Tsang VCW: “Sequence variation in the COI, ITS1, and Ts14 diagnostic antigen sequences of Taenia solium” International Journal for Parasitology 2001 (in press). 38. Garcia HH, Gonzalez AE, Gilman RH, Bernal T, Rodriguez S, Pretell EJ, Azcurra O, Parkhouse RME, Tsang VCW, Harrison LJ and The Cysticercosis Working Group in Peru. “Circulating parasite antigen in patients with hydrocephalus secondary to neurocysticercosis”, American Journal of Tropical Medicine and Hygiene, 2001 (in press) 39. Cosentino C, Velez M, Torres L, Garcia HH, and the Cysticercosis Working Group in Perú. “Cysticercosis lesions in basal ganglia are common but clinically silent” Clinical Neurology and Neurosurgery 2001 (in press).