Burden of Disease – Reference List Code 01 Asthma 02 Level 1 Respiratory Issues – Acute and Chronic Level 2 Asthma Chronic Obstructive Pulmonary Disease (COPD) Bronchitis Chronic Obstructive Pulmonary Disease (COPD) Emphysema Hay Fever/Rhinitis Infant and neonatal lung conditions Influenza Lung developments Lung surgery Other respiratory issues NEC Pneumonia Sleep apnoea Smoking related respiratory issues Hay Fever/Rhinitis Infant and neonatal lung conditions Influenza Lung developments Lung surgery Other respiratory issues NEC Pneumonia Sleep apnoea Smoking related respiratory issues 03 Cardiovascular disease Blood circulatory issues NEC Blood pressure disease Cardiac Arrhythmia Cardiomyopathy Cardiovascular surgery APPENDIX F_v1-0 Level 3 Asthma Blood circulatory issues NEC Blood pressure disease Hypertension Hypotension Atrial fibrillation Bradycardia Cardiac arrhythmia Tachycardia Cardiac Fibrosis Cardio Hypertrophy Cardiomyopathy Dilation Myocarditis Pericarditis Rheumatic heart disease Vasculitis Cardiovascular surgery Page 1 of 19 Burden of Disease – Reference List Code 03 Level 1 Level 2 Congestive heart failure Coronary artery disease Coronary heart disease Disease of the veins NEC Embolism – blockage of a blood vessel Microcirculation Other Cardiovascular disease NEC Peripheral vascular disease (PVD) Heart development issues Other cardiovascular disease NEC Preventive or health services research issues NEC Public health related issues NEC Peripheral vascular disease (PVD) Risk factors for heart disease Risk factors for heart disease Stroke – cerebrovascular Haemorrhagic Ischaemic Stroke – cerebrovascular Coronary thrombosis Deep vein thrombosis Thrombosis Thrombosis APPENDIX F_v1-0 Level 3 Congestive heart failure Aneurysm Atherosclerosis Coronary artery disease Angina Cardiac arrest Coronary heart disease Ischaemia Myocardial Infarction Disease of the veins NEC Varicose veins Venous insufficiency Arterial embolism Cerebral embolism Embolism – blockage of a blood vessel Pulmonary embolism Microcirculation Page 2 of 19 Burden of Disease – Reference List Code Level 1 Level 2 Valvular heart disease 04 Cancer and other malignant neoplasms Bone and connective tissue cancers Brain cancer Breast cancer Childhood cancers (may include some leukaemia/ lymphoma and other cancer types) Colon Endocrine cancers Gastrointestinal cancers Genitourinary cancers APPENDIX F_v1-0 Level 3 Venous thrombosis Aorta valve issues Mitral valve issues Pulmonic valve issues Tricuspid valve issues Valvular heart disease Bone and connective tissue cancers Brain cancer Breast cancer Childhood cancers (may include some leukaemia/ lymphoma and other cancer types) Medulloblastoma Neuroblastoma Retinoblastoma Bowel Colon Colorectal Endocrine cancers Ovarian Pancreatic Pituitary Testicular Thyroid Gall bladder Gastrointestinal cancers Liver Oesophagus Stomach Bladder Genitourinary cancers Kidney Page 3 of 19 Burden of Disease – Reference List Code Level 1 Level 2 Gynaecological cancers Haematological cancers Health system issues related to cancer Leukaemia Lung cancers 04 Lymphonas Melanoma Mental health and psychosocial factors related to cancer Other non-specific Basic Science cancer research Other non-specific Clinical Science cancer research Prostate cancer Public and population health related cancer issues Skin cancers (non-melanoma) Level 3 Cervical Gynaecological cancers Uterine Blood cancer (non-leukaemic) Haematological cancers Myeloma Health system issues related to cancer Leukaemia Asbestosis Lung cancers Mesothelioma Hodgkin’s disease Lymphonas Non-Hodgkin’s lymphona Melanoma Mental health and psychosocial factors related to cancer Other non-specific Basic Science cancer research Other non-specific Clinical Science cancer research Prostate cancer Public and population health related cancer issues Basal cell carcinoma Head and neck cancers Skin cancers (non-melanoma) Squamous cell carcinoma 05 Benign neoplasms Benign neoplasms Benign neoplasms 06 Congenital abnormalities Birth defects – all otherwise not specified Brain development defects Birth defects – all otherwise not specified Brain development defects APPENDIX F_v1-0 Page 4 of 19 Burden of Disease – Reference List Code 07 Level 1 Level 2 Chromosomal anomalies Congenital heart disease Craniofacial defects – cleft lip/palate Digestive system issues Down’s Syndrome Hearing Myopathies Skeletal defects Spina bifida/neural tube defects Urogenital tract malformations Vision defects Level 3 Chromosomal anomalies Congenital heart disease Craniofacial defects – cleft lip/palate Digestive system issues Down’s Syndrome Hearing Myopathies Skeletal defects Spina bifida/neural tube defects Urogenital tract malformations Vision defects Diabetes mellitus Diabetic Nephropathy Diabetic Retinopathy Gestational Type 1 – Juvenile/Insulin dependent Type 2 – Non-insulin dependent/insulin resistant/ environmental Diabetic Nephropathy Diabetic Retinopathy Gestational Type 1 – Juvenile/Insulin dependent Type 2 – Non-insulin dependent/insulin resistant/ environmental Endocrine and metabolic conditions Anaemia Anaemia Aplastic Haemolytic Iron deficiency Megaloblastic Pernicious Sickle cell Thalassemia Cystic Fibrosis Fertility Haemophilia Hormonal issues Metabolism Mitochondria disease 07 08 Cystic Fibrosis Fertility Haemophilia Hormonal issues Metabolism Mitochondria disease APPENDIX F_v1-0 Page 5 of 19 Burden of Disease – Reference List Code 09 Level 1 Diseases of the Digestive Level 2 Other endocrine issues NEC Pituitary disorders Level 3 Other endocrine issues NEC Pituitary disorders Bowel disease Bowel disease Crohn’s disease Diverticulitis Inflammatory bowel disease Irritable bowel syndrome Short bowel syndrome Digestive tract development Disease of the Pancreas Pancreatic insufficiency Pancreatitis Gall bladder and bile duct disorders Gastrointestinal motility disorders Gastro-oesophageal reflux Hernia Colitis – large intestine Cystitis – bladder Enteritis – small intestine Gastritis – stomach lining Gastroenteritis – stomach Inflammatory digestive tract disorders Peritonitis – peritoneum (lining of abdominal cavity) Cholestasis Cirrhosis (fibrosis) Cystic disease of the liver Fatty liver Haemochromatosis Liver disease Menke’s disease (copper metabolism) Primary sclerosing cholangitis Digestive tract development Disease of the Pancreas Gall bladder and bile duct disorders Gastrointestinal motility disorders Gastro-oesophageal reflux Hernia Inflammatory digestive tract disorders 09 Liver disease APPENDIX F_v1-0 Page 6 of 19 Burden of Disease – Reference List Code Level 1 Level 2 Oesophageal disorders Other digestive conditions NEC Peptic Ulcer – often caused by H.Pylori 10 Genitourinary disease Benign prostatic disorders Genitourinary developments Nephritis – inflammation of the kidneys Nephrosis or nephropathy – disease of the kidneys Other Genitourinary conditions NEC Urogenital disorders 11 Infectious and parasitic diseases APPENDIX F_v1-0 Antimicrobial/antibiotics resistance Arbovirus parasitical infections (incl Flavivirus and Alphavirus infections) – (insect, spider or crustacean borne) – includes Encephalitis Level 3 Pyogenic liver abscess Wilson’s disease (oversupply of copper in the liver) Barrett’s Oesophagus Oesophageal disorders Other digestive conditions NEC Peptic Ulcer – often caused by H.Pylori Benign prostatic disorders Genitourinary developments Glomerulonephritis Nephritis – inflammation of the kidneys Renal inflammation NEC Diabetic nephropathy Ischaemic injury Nephrosis or nephropathy – disease of the kidneys Renal or kidney disease NEC Other Genitourinary conditions NEC Bladder disorders Urinary incontinence Urinary tract infections Urogenital disorders Antimicrobial/antibiotics resistance Arbovirus parasitical infections (incl Flavivirus and Alphavirus infections) – (insect, spider or crustacean borne) – includes Encephalitis Dengue Fever Equine virus Haemorrhagic Fever (Ebola, Marburg virus) Lassa Fever Lice and mites Page 7 of 19 Burden of Disease – Reference List Code Level 1 Level 2 Childhood immunisable disease Encephalitis (mosquito borne) Gastrointestinal infections incl Staphylococcus 11 Helminth parasitical infections APPENDIX F_v1-0 Level 3 Ross River Fever Scabies Yellow Fever Childhood immunisable disease Diphtheria Measles Polio Rubella Tetanus Varicella (Chicken pox) Whooping cough Encephalitis (mosquito borne) Japanese Kunjin (Australian) Murray Valley (Australian) Cholera Clostridium perfringens Colitis Diarrhoea NEC Enteric fever Escherichia coli (E.coli) Gastroenteritis Gastrointestinal infections incl Staphylococcus Helicobacter Pylori Peritonitis Rotavirus Salmonella Shigellosis/Shigella (dysentery/diarrhoea) Typhoid fever Cysticercosis (tapeworm larvae) Helminth parasitical infections Hookworms Page 8 of 19 Burden of Disease – Reference List Code Level 1 Level 2 Herpes virus HIV/AIDS Hospital acquired infection (incl Golden Staph) Influenza (see also 2 - Respiratory Disease) Malaria (Plasmodium) Meningitis Mycobacterium Mycoses (fungal infections) 11 APPENDIX F_v1-0 Level 3 Hydatids/tapeworms Nematodes/roundworms Schistosomiasis (blood fluke infections) Trematodes (liver fluke infections) Cytomegalovirus Epstein-Barr virus Herpes virus Herpes Simplex Virus (HSV) Varicella-zoster virus (shingles) HIV/AIDS Hospital acquired infection (incl Golden Staph) Influenza (see also 2 - Respiratory Disease) Malaria (Plasmodium) Falciparum Malaria (Plasmodium) Malariae Ovale Vivax Hemophilus influenzae Meningitis Meningococcus (Neisseria) Spinal Leprosy Mycobacterium Mycobacterium avium complex (MAC) Tuberculosis Aspergillosis Candidiasis Cryptococcus Mycoses (fungal infections) Thrush Tinea Page 9 of 19 Burden of Disease – Reference List Code Level 1 Level 2 Nervous system viral infections (incl Encephalitis and Meningitis) Other Bacterial infections NEC Other non-specific infectious disease Other Parasitical infections NEC Other Viral infections NEC Pathogenesis of infectious diseases (origin and development of disease) Protozoal infections (includes Malaria and Trichomoniasis (STI)) Rickettsial infections APPENDIX F_v1-0 Level 3 Bat Lyssa virus Nervous system viral infections (incl Encephalitis and Meningitis) Poliomyelitis Prion diseases (incl CJD and TSE) Rabies Cystitis Gas Gangrene Klebsiella Legionellosis (Legionnaire’s Disease) Listeriosis Other Bacterial infections NEC Pseudomonas Other non-specific infectious disease Other Parasitical infections NEC Adenovirus Coronavirus Hantavirus Other Viral infections NEC Respiratory virus NEC Pathogenesis of infectious diseases (origin and development of disease) Amoebic dysentery Cryptosporidium Giardiasis Leishmaniasis Protozoal infections (includes Malaria and Trichomoniasis (STI)) Eastern tick borne (Queensland tick typhus) Q Fever Rickettsial infections Typhus Page 10 of 19 Burden of Disease – Reference List Code 11 Level 1 Level 2 RNA virus NEC Sexually transmitted infections (incl Herpes virus and HIV/AIDS and Hep B and Hep C Staphylococcus bacterial infections Streptococcus bacterial infections Trachoma Viral Hepatitis APPENDIX F_v1-0 Level 3 Apthovirus (incl foot and mouth disease) Cardiovirus Enterovirus Picornavirus NEC Rhinovirus RNA virus NEC Chlamydia Gonorrhoea Human Papillomavirus HPV (genital warts) Sexually transmitted infections (incl Herpes virus and HIV/AIDS and Hep B and Hep C Syphilis Trichomoniasis (vaginitis) Staphylococcus aureus (Golden Staph) Staphylococcus bacterial infections Agalactiae Bacteremia (bloodstream) Cellulitis Impetigo Necrotizing fasciitis Osteomyelitis Pharyngitis (strep throat) Pneumococcus Scarlet Fever Streptococcus bacterial infections Tonsillitis Toxic shock syndrome Trachoma Hepatitis A – inflammatory liver (faecal/oral contact, food or water borne) Hepatitis B (HBV) – life threatening chronic liver virus (STI or blood borne) Page 11 of 19 Burden of Disease – Reference List Code Level 1 Level 2 11 Zoonotic Parasitical Infections (includes Arbovirus infections) 12 13 Injuries Maternal conditions, Foetal development and Neonatal disorders APPENDIX F_v1-0 Injury Prevention Intentional Level 3 Hepatitis C (HCV) – severe inflammatory liver virus (STI or blood borne) Hepatitis D – only to HBV infected people (blood borne – shared needles) Hepatitis E – acute inflammation in liver (contaminated water, faecal/oral contact) Viral Hepatitis Anthrax Brucellosis Leptospirosis Melioidosis Plague Rat bite fever Zoonotic Parasitical Infections (includes Arbovirus infections) Unintentional Injury Prevention Child abuse Domestic violence Intentional Other intentional injuries NEC Suicide and self harm Falls Fire/burns/scalds Occupational/environmental Other unintentional injuries NEC Sports related Unintentional Vehicle accidents Foetal development (incl embryonic development from 24 Genetic Therapies and Dev) Foetal development (incl embryonic development from 24 Genetic Therapies and Dev) Page 12 of 19 Burden of Disease – Reference List Code Level 1 13 14 Mental disorders (excluding Dementia) Level 2 In vitro fertilisation Maternal health Menopause Menstruation Pregnancy Prematurity Reproduction Neonatal disorders Birth trauma and asphyxia Infections Low birth weight Neonatal disorders Other neonatal causes Adolescent developmental issues Anxiety disorders Adolescent developmental issues Anxiety Anxiety disorders Obsessive compulsive disorder Panic Phobias Stress Asperger syndrome Attention deficit hyperactivity disorder (ADHD) Autism Child abuse Childhood behavioural and developmental issues NEC Childhood learning disorders Childhood mental health Childhood mental retardation Childhood speech disorders Domestic violence Childhood mental health Domestic violence APPENDIX F_v1-0 Level 3 In vitro fertilisation Maternal health Page 13 of 19 Burden of Disease – Reference List Code Level 1 Level 2 Suicidal behaviour and self harm Level 3 Anorexia nervosa Bulimia nervosa Eating disorders Learning disorders Mental retardation Cognitive behaviour therapy Drug therapies in mental health Other mental health issues NEC Parent and family management of mental disorders Psychopathology Psychosocial issues Bipolar disorder Borderline personality disorder (rage, impulsivity, unpredictability) Depression Mood disorders Psychotic and affective disorders Schizophrenia Speech related mental health Alcoholism Drug abuse Petrol sniffing Smoking Substance abuse Suicidal behaviour and self harm Eating disorders Learning disorders Mental retardation Other mental health issues NEC 14 Psychotic and affective disorders Speech related mental health Substance abuse 15 Alzheimer’s disease and other dementias AIDS dementia complex Alzheimer’s disease Other dementias AIDS dementia complex Alzheimer’s disease Other dementias 16 Sense Organ and Sensory System Disorders Balance Hearing/sound Balance Deafness APPENDIX F_v1-0 Page 14 of 19 Burden of Disease – Reference List Code Level 1 Level 2 Smell Touch Level 3 Hearing Hearing aids Hearing/sound Otitis media Tinnitus Other sensory issues NEC Blindness Cataracts Cornea issues Diabetic retinopathy Eye surgery Glaucoma Lens development Macular degeneration Myopia Other vision and eye conditions Retinal disorders NEC Sight/vision Uveitis Smell Touch Autonomic and peripheral nervous system issues Central nervous system issues Cerebral Palsy Dyslexia Enteric nervous system issues Epilepsy Huntington’s Disease Learning, speech or memory related neurological issues Migraine Autonomic and peripheral nervous system issues Central nervous system issues Cerebral Palsy Dyslexia Enteric nervous system issues Epilepsy Huntington’s Disease Learning, speech or memory related neurological issues Migraine Other sensory issues NEC Sight/vision 16 17 Nervous System Disorders APPENDIX F_v1-0 Page 15 of 19 Burden of Disease – Reference List Code Level 1 17 18 Musculoskeletal and arthritic conditions APPENDIX F_v1-0 Level 2 Motor Neuron disease Multiple Sclerosis Muscular dystrophy Nerve development or regeneration Neurodegenerative disease NEC Neurogenesis – nerve development Neuromuscular disease NEC Other nervous system issues NEC Parkinson’s Disease Prion disease Rett’s Syndrome Spinal cord injury Stroke – neurological aspect Traumatic brain injury Level 3 Motor Neuron disease Multiple Sclerosis Muscular dystrophy Nerve development or regeneration Neurodegenerative disease NEC Neurogenesis – nerve development Neuromuscular disease NEC Neuroanatomy Neurochemistry Neuroendocrinology Neurogenetics Neuroimaging Neuropathic pain Neuropathology Neurophysiology Neuropsychiatry Neuropsychology Other nervous system issues NEC Peripheral neuropathies Parkinson’s Disease Prion disease Ret’s Syndrome Spinal cord injury Stroke – neurological aspect Traumatic brain injury Bone growth and regeneration issues Chronic back pain Connective tissue issues Fractures Joint or bone tissue replacement issues Lupus Muscle or limb movement issues Bone growth and regeneration issues Chronic back pain Connective tissue issues Fractures Joint or bone tissue replacement issues Lupus Muscle or limb movement issues Page 16 of 19 Burden of Disease – Reference List Code Level 1 Level 2 Osteoarthritis Osteoporosis Other musculoskeletal issues NEC Rheumatoid Arthritis Sjogren’s Syndrome Spinal or lumbar issues Level 3 Osteoarthritis Osteoporosis Other musculoskeletal issues NEC Rheumatoid Arthritis Sjogren’s Syndrome Spinal or lumbar issues 19 Nutritional deficiencies Infant nutrition and diet Iron deficiency anaemia Malnutrition Maternal nutrition and diet Obesity Other dietary issues NEC Infant nutrition and diet Iron deficiency anaemia Malnutrition Maternal nutrition and diet Obesity Other dietary issues NEC 20 Oral health Dental caries Dental surgery Other oral/dental health issues NEC Periodontal disease Dental caries Dental surgery Other oral/dental health issues NEC Periodontal disease 21 Skin disease Acne Atopic dermatitis/Ecszema Burns and scarring Other skin related conditions NEC Psoriasis Acne Atopic dermatitis/Ecszema Burns and scarring Other skin related conditions NEC Psoriasis Other Ill-defined conditions Alternative medicines and treatment Alternative medicines and treatment Complementary Herbal Oriental Chronic Fatigue Syndrome Familial conditions Angiogenesis (or neovascularisation) (development of blood vessels) 21 22 Chronic Fatigue Syndrome Familial conditions Haematology or blood disorders NEC (includes 8-Anaemia) APPENDIX F_v1-0 Page 17 of 19 Burden of Disease – Reference List Code Level 1 Level 2 Sleep disorders NEC Sudden Infant Death Syndrome Toxicology or poisoning issues Level 3 Haematology or blood disorders NEC (includes 8-Anaemia) Lymphedema Normal blood clotting Sepsis and septicaemia (bacterial infections of the circulating blood) Other illness issues NEC Plastic or reconstructive surgery Magnetic Resonance Imaging (MRI) Nuclear Magnetic Resonance Spectroscopy Radiography/Imaging NEC X-ray crystallography Sleep disorders NEC Sudden Infant Death Syndrome Toxicology or poisoning issues Allergy Anaesthesia and pain management Antivirals Autoimmune disease NEC Chemotherapy Drug design, delivery and antibiotics development Immunogenetics Immunopathology NEC Immunotherapy NEC Inflammatory conditions NEC Other immune system issues not elsewhere classified Radiotherapy Transplant Immunology Tumour Immunology Vaccine or immunisation issues Allergy Anaesthesia and pain management Antivirals Autoimmune disease NEC Chemotherapy Drug design, delivery and antibiotics development Immunogenetics Immunopathology NEC Immunotherapy NEC Inflammatory conditions NEC Other immune system issues not elsewhere classified Radiotherapy Transplant Immunology Tumour Immunology Vaccine or immunisation issues Other illness issues NEC Plastic or reconstructive surgery Radiography/Imaging NEC 23 Immunity and immunology NEC 23 APPENDIX F_v1-0 Page 18 of 19 Burden of Disease – Reference List Code Level 1 Level 2 Viral immunology Xenotransplantation Level 3 Viral immunology Xenotransplantation 24 Genetics – developments and therapies Embryonic developments Gene expression Gene therapy NEC Genetic defects Genetic epidemiology Inherited disorders Other genetic developments NEC Proteomics Stem cell therapy X-linked disorders Embryonic developments Gene expression Gene therapy NEC Genetic defects Genetic epidemiology Inherited disorders Other genetic developments NEC Proteomics Stem cell therapy X-linked disorders 25 Health services, public health and epidemiological research Environmental health issues Epidemiological studies NEC Health economics Health ethics issues Health policy issues Health promotion, education and counselling Health Services effectiveness, training and administration Intensive, critical or acute care Occupational health issues Other health services issues NEC Primary Health Care Public and population health issues NEC Rehabilitation issues Environmental health issues Epidemiological studies NEC Health economics Health ethics issues Health policy issues Health promotion, education and counselling Health Services effectiveness, training and administration Intensive, critical or acute care Occupational health issues Other health services issues NEC Primary Health Care Public and population health issues NEC Rehabilitation issues APPENDIX F_v1-0 Page 19 of 19