UNIVERSITY OF KENT – CODE OF PRACTICE FOR QUALITY ASSURANCE
MODULE SPECIFICATION TEMPLATE
1
The title of the module
BI614 Topics in Medical Biosciences
2
The Department which will be responsible for management of the module
Biosciences
3
The Start Date of the Module
January 2007
4
The number of students expected to take the module
60
5
Modules to be withdrawn on the introduction of this proposed module and
consultation with other relevant Departments and Faculties regarding the
withdrawal
None this is a revising of an existing module
6
The level of the module (eg Certificate [C], Intermediate [I], Honours [H] or
Postgraduate [M])
H
7
The number of credits which the module represents
15
8
Which term(s) the module is to be taught in (or other teaching pattern)
Term 2
9
Prerequisite and co-requisite modules
Prerequisite for Haematology and Cellular Pathology are BI627 Haematology
and Blood Transfusion and BI525 Introduction to Laboratory Medicine A
Prerequisite for Biochemical Investigation of Human Disease is BI626
Integrated Endocrinology and Metabolism
10
The programmes of study to which the module contributes
Biomedical Science
Biomedical Science with a Sandwich Year
Biochemistry with Medical Biosciences
11
The intended subject specific learning outcomes and, as appropriate, their
relationship to programme learning outcomes
116096067
UNIVERSITY OF KENT – CODE OF PRACTICE FOR QUALITY ASSURANCE
This module comprises several components covering key areas relevant to
Medical Biosciences. Topics are delivered by staff working in the chosen areas
and reflect current research and/or applications in Medical Biosciences.
On successful completion of this module students will have achieved three of
the following:
-
Haematology and Cellular Pathology *- an understanding of how certain
disease states affect haematological values and a knowledge of the
treatment regimes used to treat them; an understanding of the specialised
techniques used in Cellular Pathology (Programme outcomes 10,13)
-
Cancer: Biology and Treatment - An appreciation that cancer is a
collection of diseases with different clinical manifestations, risks and
treatments; an understanding of how molecular changes are responsible for
the development of individual cancers and associated with time to relapse
and death; a knowledge of the ethic issues that arise from out greater
understanding of the molecular biology of the disease. (Programme
outcomes 5,10,16,24)
-
Molecular Medicine - the ability to discuss the advantages and
disadvantages of both viral and non-viral methods for the delivery of
nucleic acids for gene therapy; the ability to describe the role played by
inappropriate cell death or survival in selected disease states and how an
understanding of these processes has led to the development of
experimental strategies for the treatment of human disease; the ability to
explain the roles played by proteomics, functional genomics and nucleic
acid based diagnostics in the discovery of novel therapeutic targets and
agents. (Programme outcomes 4,5,24)
-
Bioactive Molecules and Biomedicine -An appreciation that a range of
molecules produced by microorganisms have bioactive properties; a
knowledge of how selected bioactive molecules exert their effect on
metabolic processes; the ability to identify useful synthetic activities present
in microorganisms and to use existing information in design search
strategies to find new bioactive molecules produced by microorganisms
(Programme outcomes 8,9)
-
Epidemiology and Disease* - A knowledge of microorganisms of medical
importance, how the spread of disease is monitored in animal and human
populations and the principles of prevention and containment for various
116096067
UNIVERSITY OF KENT – CODE OF PRACTICE FOR QUALITY ASSURANCE
diseases; an understanding of the pathogenic mechanisms of specific
organisms and the importance of vaccination and immunisation policies at
local and national levels. (Programme outcomes 7,8,15)
-
Biochemical Investigation of Human Disease* - A knowledge of the
principles underpinning biochemical screening; an ability to discuss the
application of biochemical techniques to the detection and management of
human disease and the impact of genetic and environmental factors on the
development of human disease.(Programme outcomes 9,11)
Topics marked * are compulsory for students taking the accredited Biomedical
Science degree programme
12
The intended generic learning outcomes and, as appropriate, their
relationship to programme learning outcomes
The following generic learning outcomes are achieved in all of the options
available
13
-
the ability to retrieve, analyse and evaluate information from text books,
-
the development of written communication skills (33)
primary research papers and review articles (19,28)
A synopsis of the curriculum
-
Haematology and Cellular Pathology – antiphospholipid syndrome ,
advances in anticoagulation; Von Willibrands disease and its treatment,
factor XII – essential or irrelevant, use of gene therapy in the treatment of
Haemophilia and the development and use of “artificial blood”
-
Procedures for specific substances and tissues, methods for tissue markers
and products, cytopreparatory techniques, diagnostic cytology, fine needle
biopsy, post mortem techniques and tissue display
-
Cancer : Biology and Treatment – incidence, causes and prevention of
cancer; the pathology of cancer; growth regulation and intracellular
signalling; oncogenes and mechanisms of cell transformation; tumour
suppressor genes and genetic instability; metastasis; inherited predisposition
to cancer; current and new treatments for cancer; ethical issues in cancer.
-
116096067
Molecular Medicine – physical methods for gene delivery; viral vectors for
gene therapy; antisense technology and ribozymes; functional genomics and
UNIVERSITY OF KENT – CODE OF PRACTICE FOR QUALITY ASSURANCE
proteomics; apoptosis in disease; anti-CD33 engineered lymphocytes for the
treatment of myeloid leukaemia.
-
Bioactive Molecules and Biomedicine - types of bioactive molecules;
secondary metabolites and antibiotics – their synthesis by microbes;
mechanisms of antibiotic action; other pharmacologically active microbial
products; β lactam antibiotics; the use of genetically modified bacteria;
biotransformations and strategies for finding new bioactive agents.
-
Epidemiology and Disease – the epidemiology and prevention of
Salmonella, Diphtheria, Influenza, Zoonotic diseases, Meningitis and
Dermatophyte infection; the epidemiology of Staphylococcus – old pathogen
or emerging problem?; methodology used in epidemiology.
-
Biochemical Investigation of Human Disease – screening for disease –
concepts, rationale and screening programmes, application of biochemical
techniques to paediatrics and inborn errors of metabolism, tumour markers,
liver function, iron and porphyries, enzymes and their use in laboratory
medicine, clinical applications of protein biochemistry, nutrition in health
and disease, lipids and atherosclerosis.
14
Indicative Reading List
-
Haematology and Cellular Pathology
Essential Haematology – A.V. Hoffbrand, S.M. Lewis and E.G.D.
Tuddenham
Haemostasis and Thrombosis – T.G. Deloughery
Relevant research papers will be recommended during the course
-
Cancer: Biology and Treatment
Cancer Biology (2nd Edition) R.J.B. King
-
Molecular Medicine
Lecture Notes on Molecular Medicine (2001) J. Bradley et al
Human Molecular Genetics 2 (1999) T. Strachan and A.P. Read
Essentials of Medical Genomics (2003) S.M. Brown
-
Bioactive Molecules and Biomedicine
Discovery and Isolation of Microbial products (1985) M.S. Verrall
The Biosynthesis of Secondary Metabolites (1989) R.B. Herbert
Biotransformations (2000) K. Faber
116096067
UNIVERSITY OF KENT – CODE OF PRACTICE FOR QUALITY ASSURANCE
-
Epidemiology and Disease
Medical Microbiology (1998) Mims, Playfair, Roitt, Wakelin and Williams
Principles of Bacteriology and Immunity, Topley and Wilson
-
Biochemical Investigation of Human Disease
Clinical Biochemistry (3rd Edition) A. Gaw, M.J. Murphy, R.A. Cowan, D.S.J.
O’Reilly, M.J. Stewart and J. Shepherd.
Clinical Biochemistry Metabolic and Clinical Aspects. W.J. Marshall and
S.K. Bangert (Eds)
15
Learning and Teaching Methods, including the nature and number of contact
hours and the total study hours which will be expected of students, and how
these relate to achievement of the intended learning outcomes
Contact Hours – 28 hours (lectures )
Self Study -
122 hours ( recommended reading 30 hours, preparation for
assessment 30 hours and preparation for examination 62 hours)
16
Assessment methods and how these relate to testing achievement of the
intended learning outcomes
Coursework 30% - Each of the options has a written assessment to test
achievement of the subject specific and generic
learning outcomes for each
option. Students complete a total of three assessments according to their
chosen options, each assessment is worth 10% of the module mark.
-
Haematology and Cellular Pathology
-
A short essay
-
Cancer: Biology and Treatment
A short essay on a current issue in cancer ( 400 word summary)
-
Molecular Medicine
-
Journal club – preparation of a presentation based on an allocated research
-
Bioactive Molecules and Biomedicine
-
-
-
Epidemiology and Disease
-
paper
Report on a selected class of bioactive molecules
essay based on the problems relating to an infectious agent and the
mechanism to
116096067
control /eradicate the disease from the patient.
UNIVERSITY OF KENT – CODE OF PRACTICE FOR QUALITY ASSURANCE
-
Biochemical Investigation of Human Disease
Structured review of a published article
Examination 70%
17
Implications for learning resources, including staff, library, IT and space
No additional resources are required
18
A statement confirming that, as far as can be reasonably anticipated, the
curriculum, learning and teaching methods and forms of assessment do not
present any non-justifiable disadvantage to students with disabilities
As far as can be reasonable anticipated, the curriculum, learning and teaching
methods and forms of assessment do not present any non-justifiable
disadvantages to students with disabilities.
Statement by the Director of Learning and Teaching: "I confirm I have been
consulted on the above module proposal and have given advice on the correct
procedures and required content of module proposals"
................................................................
Director of Learning and Teaching
..............................................
Date
Statement by the Head of Department: "I confirm that the Department has
approved the introduction of the module and will be responsible for its resourcing"
.................................................................
Head of Department
116096067
..............................................
Date