Biology 211 Practice Exam III (100 pts.) Multiple choice (3 pts. Each). Select the one best answer and fill in the appropriate space on the SCANTRON provided. 1. If the parent cell has fourteen chromosomes prior to mitosis, how many chromosomes will each daughter cell have? a. twenty-eight b. fourteen c. seven d. twelve 2. Which of the germ layers is most closely involved with the development of the muscles? a. ectoderm b. mesoderm c. endoderm d. neurula 3. a. b. c. d. During protein synthesis, an anticodon on transfer RNA (tRNA) pairs with DNA nucleotide bases ribosomal RNA nucleotide bases messenger RNA nucleotide bases other tRNA nucleotide bases 4. a. b. c. d. e. Which component is not directly involved in the process of translation? mRNA DNA tRNA ribosomes GTP 5. In his work with pneumonia-causing bacteria and mice, Griffith found that a. the protein coat from pathogenic cells was able to transform nonpathogenic cells. b. heat-killed pathogenic cells caused pneumonia. c. some chemical from pathogenic cells was transferred to non-pathogenic cells, making them pathogenic. d. the polysaccharide coat of bacteria caused pneumonia. 1 6. a. b. c. d. e. In what phase of mitosis are the chromosomes moving toward the poles? prophase metaphase anaphase telophase interphase 7. a. b. c. d. The site on DNA where the two strands unwind during replication is called Okazaki fragment promoter replication fork DNA polymerase 8. a. b. c. d. Which of these stages is mismatched? cleavage--cell division blastula--gut formation gastrula--involution of cells neurula--nervous system formation 9. a. b. c. d. e. RNA processing is the same as transcription is an event that occurs after RNA is transcribed is a function of transfer RNA involves the removal of introns both b and d are correct 10. (10 points) Fill in the blanks with the appropriate term a. Enzyme that speeds the formation of mRNA from a DNA template. _________________________________ b. Three nucleotides of DNA or RNA; it codes for a particular amino acid or termination of translation.__________________________ c. The enzyme that catalyzes the formation of peptide bonds between amino acids during protein synthesis._______________________ d. Process of removing mispaired bases in DNA so the sequence can be restored to its normal form.__________________________ e. The model of DNA replication that predicts that each strand of DNA serves as the instructions for synthesizing a new strand of DNA. ____________________ f. Proteins that assist RNA polymerase in binding to the promoter and initiating transcription are called ____________________. 2 (15 pts.) Match the following processes with their location in eukaryotic cells. Some answers may be used more than once, others may not be used at all. a. b. c. d. e. nucleus cytoplasm endoplasmic reticulum nucleolus mitochondria 11. DNA replication occurs in ____________. 12. Transcription occurs in _______________. 13. The subunits of ribosomes are assembled in _____________________. 14. Translation of secreted proteins occurs on ribosomes that migrate to _______________________. 15. Removal of introns, addition of a 5' cap and polyadenylation of pre-mRNAs occurs in _____________________. 16. (9 pts.) Describe three differences between normal cells and cancer cells. 3 17. (16 points) a. What are embryonic stem cells? b. Why might it be possible to use them to treat diseases such as Parkinson's or Alzheimer's where the tissues have begun to degenerate? c. Give several major arguments for and against human cloning as a way of producing embryonic stem cells. 4 18. (21 pts.) Briefly define any seven of the following terms a. blastula b. prophase c. ectoderm d. lagging strand e. differentiation f. cytokinesis g. release factor h. cloning i. spindle 5 6