Curriculum Vitae
Name:
Date of CV Revision:
e-mail:
Séamus Hussey
April 2013
seamus.hussey@ucd.ie
Degrees, Certifications and Licensures
March 2012
Fellowship of the Royal College of Physicians of Ireland, Dublin, Ireland
October 2011
Fellowship of the Faculty of Paediatrics, RCPI, Dublin, Ireland
June 1999
MB BCh BAO (Hons Mode A) BMedSc
University College Cork, NUI, Cork, Ireland
Consultant Appointments
September 2010 -
June 2009 – June 2010
Consultant Gastroenterologist and Clinical Lecturer
Our Lady’s Children’s Hospital, Crumlin, Dublin 12 and
School of Medicine, University College Dublin, Dublin
Locum Consultant Gastroenterologist
The Hospital for Sick Children, Toronto, Ontario, Canada
Sub-Specialist Training Appointments
July 2006 – 2009
January – June 2006
July – December 2005
Fellow in Gastroenterology, Hepatology and Nutrition
The Hospital for Sick Children, Toronto, Ontario, Canada
Gastroenterology Specialist Registrar
Our Lady’s Children’s Hospital, Crumlin, Dublin 12
Hepatology Specialist Registrar
Our Lady’s Children’s Hospital, Crumlin, Dublin 12
Current research activities
1. DOCHAS Project: Determinants and outcomes of children and adolescents with inflammatory
bowel disease in Ireland (January 2012-)
2. GROWTH Study: Growth Relapse and Outcomes with Therapy in Crohn's Disease (Pediatric
Crohn's GROWTH study)
3. Determinants of Vitamin D status in children with Coeliac disease or Inflammatory Bowel Disease
(2011-2012)
4. Investigating the role of the innate immune system in paediatric coeliac disease (April 2012-)
5. iNEOPICS: interNational Early Onset Paediatric IBD Cohort Study (January 2013-)
Manuscripts published in peer reviewed journals
1. Crowley E, Bourke B, Hussey S. How to use Helicobacter pylori testing in paediatric practice.
Arch Dis Child Educ Pract Ed. 2013 Feb;98(1):18-25
2. Fouhy F, Guinane CM, Hussey S, Wall R, Ryan CA, Dempsey EM, Murphy B, Ross RP,
Fitzgerald GF, Stanton C, Cotter PD. High throughput sequencing reveals the incomplete, shortterm recovery of infant gut microbiota following parenteral antibiotic treatment with ampicillin and
gentamicin. Antimicrob Agents Chemother. 2012 Nov;56(11):5811-20.
3. Raju D, Hussey S, Jones NL. Crohn disease ATG16L1 polymorphism increases susceptibility to
infection with Helicobacter pylori. Autophagy. 2012 Sep;8(9):1387-8.
4. Turner D, Levine A, Escher JC, Griffiths AM, Russell RK, Dignass A, Dias JA, Bronsky J,
Braegger CP, Cucchiara S, de Ridder L, Fagerberg UL, Hussey S, Hugot JP, Kolacek S, Kolho KL,
Lionetti P, Paerregaard A, Potapov A, Rintala R, Serban DE, Staiano A, Sweeny B, Veerman G,
Veres G, Wilson DC, Ruemmele FM; European Crohn's and Colitis Organization; European
Society for Paediatric Gastroenterology, Hepatology, and Nutrition. Management of pediatric
ulcerative colitis:joint ECCO and ESPGHAN evidence-based consensus guidelines. J Pediatr
Gastroenterol Nutr. 2012 Sep;55(3):340-61.
5. Hope B, Shahdadpuri R, Dunne C, Hamzawi M, O’Driscoll K, Quinn S ,Broderick AM, Hussey S,
Bourke B. Rapid Rise in Incidence of Irish Paediatric Inflammatory Bowel Disease. Arch Dis
Child. Jul;97(7):590-4
6. Raju D, Hussey S, Ang M, Terebiznik MR, Sibony M, Galindo-Mata E, Gupta V, Blanke SR,
Delgado A, Romero-Gallo J, Ramjeet M, Mascarenhas H, Peek RM, Correa P, Streutker C, Hold G,
Kunstmann E, Yoshimori T, Silverberg MS, Girardin SE, Philpott DJ, El Omar E, Jones NL.
Vacuolating cytotoxin (VacA) and the Crohn's disease ATG16L1 variant alter autophagy and
susceptibility to Helicobacter pylori infection in humans. Gastroenterology. 2012
May;142(5):1160-71
7. Hussey S, Fleming P,Rowland M, Harty S, Chan L, Broderick A, Drumm B, and Bourke B.
Disease outcome for children who present with oral manifestations of Crohn’s disease. Eur Arch
Paediatr Dent. 2011 Jun;12(3):169-71
8. Hussey S, Wall R, Gruffman E, O'Sullivan L, Ryan CA, Murphy B, Fitzgerald G, Stanton C, Ross
RP. Parenteral antibiotics reduce bifidobacteria colonization and diversity in neonates. Int J
Microbiol. 2011;2011. pii: 130574.
9. Mourad-Baars PEC*, Hussey S*, and Jones NL. The year in Helicobacter: Pediatrics.
Helicobacter. 2010 Sep;15 Suppl 1:53-9
10. Hussey S, Kelleher KT, Ling SC. Emergency management of major gastrointestinal hemorrhage in
children. Clinical Pediatric Emergency Medicine. 2010 Sept;11(3):207-216
11. Mahendrasingh R*, Hussey S*, Philpott DJ, Travassos LH. ‘Nodophagy’: New cross roads in
Crohn’s disease pathogenesis. Gut Microbes. Gut Microbes. 2010 Sep;1(5):307-315
12. Kayath CA, Hussey S, El Hajjami N, Nagra K, Philpott D, Allaoui A. Escape of intracellular
Shigella from autophagy requires binding to cholesterol through the type III effector, IcsB.
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Microbes Infect. 2010 Nov;12(12-13):956-66
13. Travassos LH, Carneiro LA*, Mahendrasingh R*, Hussey S, Kim Y, Yuan L, Soares F,
Magalhães JG, Le Bourhis L, Boneca IG, Allaoui A, Jones NL, Nuñez G, Girardin SE and Philpott
DJ. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the site of bacterial entry. Nat
Immunol. 2010 Jan;11(1):55-62.
14. Hussey S*, Travassos LH* and Jones NL. Autophagy as an emerging dimension to innate and
adaptive immunity. Semin Immunol. 2009 Aug;21(4):233-41
15. Wall R, Ross P, Ryan CA, Hussey S, Murphy BP, Fitzgerald GF and Stanton C. Role of gut
microbiota in early infant development. Clinical Medicine: Pediatrics 2009;3: 45-54
16. Hussey S, Bourke B, Broderick A, Phelan E and McDermott M. Cryptogenic, multifocal, ulcerous
stenosing enteritis as a manifestation of enterocolic venopathy. J Pediatr Gastroenterol Nutr. 2008
Jul;47(1):107-9
17. Hussey S, Terebiznik MR and Jones NL. Autophagy: healthy eating and self digestion for the
gastroenterologist. J Pediatr Gastroenterol Nutr. 2008 May;46(5):496-506
18. Wall R, Hussey SG, Ryan CA, O'Neill M, Fitzgerald G, Stanton C, Ross RP. Presence of two
Lactobacillus and Bifidobacterium probiotic strains in the neonatal ileum. ISME J. 2008
Jan;2(1):83-91
19. Wall R, Fitzgerald G, Hussey S, Ryan T, Murphy B, Ross P, Stanton C. Genomic diversity of
cultivable Lactobacillus populations residing in the neonatal and adult gastrointestinal tract.
FEMS Microbiol Ecol. 2007 Jan;59(1):127-37
20. Hussey SG, Ryan CA and Murphy BP. Comparison of three manual ventilation devices using an
intubated mannequin. Arch Dis Child Fetal Neonatal Ed. 2004 Nov;89(6):490-3
21. Rosberg-Cody E, Ross RP, Hussey S, Ryan CA, Murphy BP, Fitzgerald GF, Devery R, Stanton C.
Mining the microbiota of the neonatal gastrointestinal tract for conjugated linoleic acid-producing
bifidobacteria. Appl Environ Microbiol. 2004 Aug;70(8):4635-41
22. Sharif F, Hussey S, Gill D. The tale of a blue toddler. Ir Med J. 2003 Sep;96(8):248-9
* co-authorship
Book Chapters
1. Gut microbial interactions. Wine E, Hussey S and Jones NL, in Walker’s Pediatric Gastrointestinal
Disease: Physiology, Diagnosis, Management; 6th Edition (Editors:Kleinman, Goulet, MieliVergagni, Sherman, Schneider) – submitted January 2013
2. Helicobacter pylori in childhood. Hussey S and Jones NL, in Pediatric Gastrointestinal and Liver
Disease; 4th Edition (Editors: Wyllie, Hyams, and Kay) – December 2010
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