Sameer U. Kalghatgi
2014 Walnut St, Apt 205 • Philadelphia, PA-19103 • Tel: 267-231-6595 •suk22@drexel.edu
• www.sameerkalghatgi.com
A highly accomplished Electrical Engineering PhD Candidate with a strong background in
molecular and cell biology, oxidative stress, biochemistry, non-thermal electrical plasma, and
medical device development along with 4 years experience in successfully conducting
hypothesis driven multidisciplinary scientific research, seeking a position as a Research
Scientist where these skills will add greater or similar value
PROFILE
1. Exceptional skills in DNA damage response, DNA damage repair pathways, promotion and
inhibition of angiogenesis, design, implementation of successful completion of in-vivo animal
studies, apoptosis, cellular signaling and phosphorylation, hands on experience in primary tissue
and mammalian cell culture, lipid peroxidation, RNA interference, Western blots, flow cytometry.
2. Energetic results oriented leader, innovative problem solver, and an enthusiastic team player
capable of working independently or in a challenging fast-paced team-centered multidisciplinary
environment. Critical thinker with a demonstrated ability to acquire and apply scientific knowledge
and skills rapidly.
3. Significant experience in experimental design, scientific planning, execution, interpretation of
relevant experiments, and troubleshooting.
4. Exceptional communication and documentation skills with various talks at international conferences,
published peer reviewed journal and conference papers.
EDUCATION
Drexel University, Philadelphia PA
2004 – Present
PhD Expected Jan 2010, Electrical and Computer Engineering
Academic Advisors: Prof. G. Friedman and Dr. A. Fridman (co-advisor)
Research Interests: Non-Thermal Atmospheric Pressure Plasma, DNA damage and repair, Dielectric
Barrier Discharge Plasma, Interaction of Non-thermal Plasma with Cells, Plasma Medicine, and Clinical
Applications of Non-Thermal Plasma like Blood Coagulation, Apoptosis, Angiogenesis and Wound
Healing
Dissertation: “Interaction of Non-Thermal Atmospheric Pressure Plasma with Mammalian Cells”
Dissertation Committee: Dr. Gary Friedman, Dr. Jane Azizkhan-Clifford, Dr. Alisa Morss Clyne, Dr.
Alexander Fridman
Veermata Jijabai Technological Institute (VJTI), Mumbai, India
Bachelor of Engineering (BE), Electrical Engineering, Jun 2003
Thesis: “Electrical and Heat Flow Simulation of MEMS structures using SPICE
1999 – 2003
JOURNAL PUBLICATIONS
1. Endothelial Cell Proliferation is enhanced by Low Dose Non-Thermal Plasma Treatment
through Fibroblast Growth Factor-2 Release, S. Kalghatgi, A. Fridman, G. Friedman, A. Clyne.
Annals of Biomedical Engineering, 2009 (Under Review)
2. DNA Damage in Mammalian Cells by Non-Thermal Atmospheric Pressure Microsecond
Pulsed Dielectric Barrier Discharge Plasma is not mediated via Lipid Peroxidation, S.
Kalghatgi, G. Fridman, A. Fridman, G. Friedman. IEEE Transactions on Plasma Science, 2009
(Under Review)
3. Non-Thermal Plasma Promotes Apoptosis in Melanoma Cancer Cells, S. Kalghatgi, E.
Podolsky, E. Cerchar, R. Sensenig, G. Fridman, A. Shereshevsky, A. Fridman, G. Friedman, J.
Azizkhan-Clifford, A. Brooks. 2009 (Manuscript to be submitted to Cancer Letters).
4. Reactive Oxygen Species mediate Interaction of Non – Thermal Plasma with Mammalian
Cells, S. Kalghatgi, C. Kelly, E. Cerchar, A. Fridman, G. Friedman, J. Azizkhan-Clifford. 2009
(Manuscript to be submitted to PNAS)
5. DNA Damage in Mammalian Cells by Non-Thermal Atmospheric Pressure Microsecond
Pulsed Dielectric Barrier Discharge Plasma is not mediated by Ozone, S. Kalghatgi, A.
Fridman, J. Azizkhan-Clifford, G. Friedman. 2009 (Manuscript to be submitted to the Journal of
Physics D: Applied Physics)
6. Selective Induction of Apoptosis by Non-Thermal Atmospheric Pressure Plasma in
transformed malignant cells over normal mammalian cells, S. Kalghatgi, E. Cerchar, K.
Arjunan, E. Podolsky, A. Fridman, J. Azizkhan-Clifford, A. Brooks, G. Friedman. 2009 (Manuscript
to be submitted to Plasma Processing and Polymers)
7. Effects of Oxidative Stress on Mammalian Cells – A Review, S. Kalghatgi, J. Azizkhan-Clifford,
A. Fridman, G. Friedman. 2009 (Manuscript to be submitted to Plasma Chemistry and Plasma
Processing)
8. Toxicity Analysis of Non-Thermal Atmospheric Pressure Plasma Treatment of Intact Skin, A.
Wu, S. Kalghatgi, D. Dobrynin, R. Sensenig, E. Podolsky, S. Joshi, G. Fridman, K. Wasko, M.
Balasubramanian, A. Fridman, K. Barbee, G. Friedman, A. Brooks. 2009 (Manuscript to be
submitted to Journal of Surgical Research)
9. Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier
Discharge Plasma, S. Kalghatgi, G. Fridman, M. Cooper, G. Nagaraj, M. Peddinghaus, M.
Balasubramanian, V. N. Vasilets, A. Gutsol, A. Fridman, G. Friedman, IEEE Transactions on
Plasma Science, Volume 35, Issue 5, Part 2, Oct. 2007, pp. 1559-1566.
10. Manipulation of Nonmagnetic Nanobeads in Dilute Ferrofluid, D. Halverson, S. Kalghatgi, B.
Yellen, G. Friedman, Journal of Applied Physics, 99 (8): April, 2006
11. Electrical and Heat Flow Simulation of MEMS structures using SPICE, N. Naik, S. Kalghatgi,
A. Ghangrekar, S. Shetty, P. R. Apte, International Journal of Computational Engineering Science,
2003, 4(2) p 397-400.
AWARDS AND HONORS
1. Highly Commended Citation for the 2009 Drexel University Excellence in Research Award
2. IEEE Student Travel Award, 17th IEEE International Pulsed Power Conference, Jun 29 – Jul 2
2009, Washington D.C., USA.
3. Honorable Mention for the PhD level Student Poster Competition at the ASME 2009 Summer
Bioengineering Conference, Jun 17 - Jun 21 2009. Lake Tahoe, CA, USA
4. Invited Talk at the 36th IEEE International Conference on Plasma Science, May 31 – Jun 4 2009,
San Diego, CA, USA.
5. IEEE Student Travel Award, 36th IEEE International Conference on Plasma Science, May 31 –
Jun 4 2009, San Diego, CA, USA.
6. Drexel University 2008-09 George Hill Jr. Endowed Fellow
7. Finalist for the Student Paper Excellence Award at the 61st Gaseous Electronics Conference,
Oct 13th-17th 2008, Dallas, TX, USA.
8. NSF Student Travel Award to attend the 61st Gaseous Electronics Conference, Oct 13th-17th 2008,
Dallas, TX
9. NSF Student Travel Award to attend Gordon Research Conference on Plasma Processing
Science, Jul 13th-18th 2008 Mt. Holyoke, South Hadley, Massachusetts
10. Best Student Paper Award at the 36th IEEE International Conference on Plasma Science, Jun
15th-19th 2008, Karlsruhe, Germany
11. Highly Commended Citation for the 2008 Drexel University Excellence in Research Award
12. Nominated for 2008 Drexel University Excellence in Teaching Award
13. Recipient of the 2008 Drexel University International Travel Award
14. Finalist for Best Student Paper Award at the 35th IEEE International Conference on Plasma
Science, Albuquerque, New Mexico, Jun 16th - 22nd 2007
15. 2007 Lee Smith Travelling Fellowship for travel to 18th International Symposium on Plasma
Chemistry, Kyoto, Japan
16. IEEE Student Travel Award, 34th IEEE International Conference on Plasma Science, Albuquerque
New Mexico, Jun15th - Jun19th 2007.
17. Honorable mention, 7th Drexel University Annual Research Day, 2005.
18. 2004 Dean’s Fellowship from Drexel University.
ORAL TALKS
1. Non-Thermal Plasma Enhances Endothelial Cell Proliferation Through Fibroblast Growth
Factor-2 Release, S. Kalghatgi, A. Fridman, Alisa Morss-Clyne, G. Friedman, 36th IEEE
International Conference on Plasma Science (ICOPS), May 29th - Jun 4th 2009, San Diego,
California, USA (invited).
2. Effects of Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma
Treatment on Mammalian Cells, S. Kalghatgi, C. Kelly, E. Cerchar, A. Fridman, G. Friedman, J.
Azizkhan-Clifford, Discovery Day 2009, Drexel University College of Medicine, Oct 7th 2009,
Philadelphia, PA, USA.
3. Comparison of Different Non-Thermal Plasma Treatments of Mammalian Cells, S. Kalghatgi,
C Kelly, E. Cerchar, A Fridman, J Azizkhan-Clifford, G Friedman, 36th IEEE International
Conference on Plasma Science (ICOPS), May 29th - Jun 4th 2009, San Diego, California, USA.
4. Non-Thermal Plasma Enhances Proliferation of Endothelial Cells, S. Kalghatgi, A. Fridman,
Alisa Morss-Clyne, G. Friedman, 2nd International Conference on Plasma Medicine (ICPM-2), Mar
16th – Mar 20th 2009, San Antonio, TX, USA.
5. Toxicity of Direct Non-Thermal Plasma Treatment of Living Tissue, A.S. Wu, S. Kalghatgi, D.
Dobrynin, R. Sensenig, G. Fridman, M. Balasubramanian, K. Barbee, A. Fridman, G. Friedman,
A.D. Brooks, Trauma and Critical Care 6: Burns/Wound Healing, 4th Annual Academic Surgical
Congress (ASC), February 3-6, 2009, Sanibel Harbor Resort, Fort Myers, FL, USA. Presented by:
A. S. Wu
6. Interaction of Non-Thermal Dielectric Barrier Discharge Plasma with DNA inside Cells
(Contributed talk and selected as finalist for Student Paper Excellence Award), S. Kalghatgi, C.
Kelly, G. Fridman, J. Azizkhan, A. Fridman and G. Friedman. 61st Annual Gaseous Electronics
Conference, Oct 13th-Oct 17th, Dallas, TX, USA
7. Non-Thermal Dielectric Barrier Discharge Plasma Treatment of Endothelial Cells, S.
Kalghatgi, G. Fridman, A. Fridman, G. Friedman, A. Morss-Clyne, 30th International Conference of
the IEEE Engineering in Medicine and Biology (EMBC), Aug 20th-Aug 24th 2008, Vancouver,
Canada. Presented by: Alisa Morss Clyne
8. Penetration of Direct Non-Thermal Plasma Treatment into Living Cells (Contributed Talk), S.
Kalghatgi, C Kelly, G Fridman, A Fridman, J Azizkhan-Clifford, G Friedman, 35th IEEE
International Conference on Plasma Science (ICOPS), June 15-19 2008, Karlsruhe, Germany.
9. Toxicity of Non-Thermal Plasma Treatment of Endothelial Cells (Contributed Talk), S.
Kalghatgi, G Fridman, A Fridman, A Morrs-Clyne, G Friedman, 35th IEEE International Conference
on Plasma Science (ICOPS), June 15-19 2008, Karlsruhe, Germany.
10. Medical applications of direct strongly non-equilibrium plasmas, G. Friedman, G. Fridman, S.
Kalghatgi , R. Sensenig, A. Shereshevsky, L. Peddinghaus, M. Balasubramanian, M. Jost, A.
Brooks, D. Dobrynin, M. Cooper, A. Fridman, A. Gutsol, First International Conference on Plasma
Medicine (ICPM-1), October 15th - 18th, 2007, Corpus Christi, TX. Presented by: G. Friedman.
11. Physical and biological mechanisms of plasma interaction with living tissue, A. Fridman, G.
Fridman, R. Sensenig, A. Shereshevsky, L. Peddinghaus, M. Balasubramanian, M. Jost, A. Brooks,
D. Dobrynin, S. Kalghatgi, M. Cooper, A. Gutsol, G. Friedman, First International Conference on
Plasma Medicine (ICPM-1), October 15th - 18th, 2007, Corpus Christi, TX. Presented by: A.
Fridman.
12. Non-thermal atmospheric plasma induces apoptosis in melanoma cancer cells, A. Brooks, G.
Fridman, R. Sensenig, A. Shereshevsky, L. Peddinghaus, M. Balasubramanian, M. Jost, D.
Dobrynin, S. Kalghatgi, M. Cooper, A. Fridman, A. Gutsol, G. Friedman, First International
Conference on Plasma Medicine (ICPM-1), October 15th - 18th, 2007, Corpus Christi, TX.
Presented by: A. Brooks.
13. Medical applications of Floating Electrode Dielectric Barrier Discharge (FE-DBD), G. Fridman,
R. Sensenig, A. Shereshevsky, L. Peddinghaus, M. Balasubramanian, M. Jost, A. Brooks, D.
Dobrynin, S. Kalghatgi, M. Cooper, A. Fridman, A. Gutsol, G. Friedman, First International
Conference on Plasma Medicine (ICPM-1), October 15th - 18th, 2007, Corpus Christi, TX.
Presented by: G. Fridman.
14. Medical Aspects of Plasma Interaction with Living Tissue, G. Friedman, G. Fridman, R.
Sensenig, A. Shereshevsky, A.S. Wu, M.L. Peddinghaus, M. Balasubramanian, M. Jost, A. Brooks,
R. Hamilton, D. Dobrynin, S. Kalghatgi, M. Cooper, A. Gutsol, A. Fridman, NATO Advanced Study
Institute (ASI), Plasma Assisted Decontamination of Biological and Chemical Agents, September
16-26, 2007, Çesme, Turkey. Presented by: G. Friedman.
15. Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier
Discharge Plasma (Contributed Talk), S. Kalghatgi, G. Fridman, M. Cooper, G. Nagaraj, M.
Peddinghaus, M. Balasubramanian, V. Vasilets, A. Gutsol, A. Fridman, G. Friedman, 34th IEEE
International Conference on Plasma Science, June 17-22 2007, Albuquerque, New Mexico, USA
16. Non-Equilibrium Dielectric Barrier Discharge Plasma Promoting Apoptotic Behavior in
Melanoma Skin Cancer Cells, G. Fridman, S. Kalghatgi, A. Fridman, A. Gutsol, V. Vasilets, G.
Friedman, R. Sensenig, A. Shereshevsky, M. Balasubramanian, M. Jost, A. Brooks, The 34th IEEE
International Conference on Plasma Science, June 17-22, 2007, Albuquerque, New Mexico.
Presented by: G. Fridman
CONFERENCE PUBLICATIONS
1. Cell proliferation following non-thermal plasma is related to reactive oxygen species induced
fibroblast growth factor-2 release, S. Kalghatgi, A. Fridman, G. Friedman, A. Morss-Clyne. To
appear in the proceedings of the 31st International Conference of the IEEE Engineering in Medicine
and Biology (EMBC), Sep 2nd- Sep 6th 2009, Minneapolis, Minnesota, USA.
2. Low Dose Non-Thermal Plasma Interacts with Mammalian Cells Indirectly through
Modification of the Cell Culture Medium, S. Kalghatgi, C. Kelly, E. Cerchar, A. Fridman, J.
Azizkhan-Clifford, G. Friedman, To appear In Abstracts and full papers 19th International
Symposium on Plasma Chemistry, Jul 26th - July 31st 2009, Bochum, Germany.
3. On the Interaction of Non-Thermal Atmospheric Pressure Plasma with Tissues, S. Kalghatgi,
C. Kelly, E. Cerchar, R. Sensenig, A. Brooks, A. Fridman, A. Morss-Clyne, J. Azizkhan-Clifford,
G. Friedman. To appear in the Proceedings of the 17th IEEE Pulsed Power Conference (PPC), Jun
29 - Jul 2 2009, Washington D.C., USA.
4. Toxicity of Direct Non-Thermal Atmospheric Pressure Plasma Treatment of Living Tissue,
S. Kalghatgi, D. Dobrynin, A. Wu, E. Podolsky, E. Cerchar, G. Fridman, A. Fridman, A. Brooks,
K. Barbee, G. Friedman. To appear in the Proceedings of the 17th IEEE Pulsed Power Conference
(PPC), Jun 29 - Jul 2 2009, Washington D.C., USA.
5. Non-Thermal Dielectric Barrier Discharge Plasma Treatment of Endothelial Cells, S.
Kalghatgi, G. Fridman, A. Fridman, G. Friedman, A. Morss-Clyne, Proceedings of the 30th
International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Aug
20th-Aug 24th 2008, Vancouver, Canada pp. 3578 – 3581.
6. Penetration of Direct Non-Thermal Plasma Treatment into Living Cells, S. Kalghatgi, C. Kelly,
G. Fridman, A. Fridman, J. Azizkhan-Clifford, G. Friedman, Proceedings of the IEEE 35th
International Conference on Plasma Science, Jun 15th – 19th 2008, Karlsruhe, Germany.
7. Toxicity of Non-thermal Plasma Treatment of endothelial cells, S. Kalghatgi, G. Fridman, A.
Fridman, G. Friedman, A. Morss Clyne, Proceedings of the IEEE 35th International Conference on
Plasma Science, Jun 15th – 19th 2008, Karlsruhe, Germany.
8. Toxicity Analysis of Direct Nonthermal Plasma Treatment of Living Tissue, S. Kalghatgi, D.
Dobrynin, A. Wu, R. Sensenig, G. Fridman, M. Balasubramanian, K. Barbee, A. Brooks, A.
Fridman, G. Friedman, , Proceedings of the IEEE 35th International Conference on Plasma
Science, Jun 15th – 19th 2008, Karlsruhe, Germany.
9. Applications of Non Thermal Atmospheric Pressure Plasma in Medicine, S. Kalghatgi, D.
Dobrynin, G. Fridman, M. Cooper, G. Nagaraj, L. Peddinghaus, M. Balasubramanian, K. Barbee, A.
Brooks, V. Vasilets, A. Gutsol, A. Fridman, and G. Friedman, in NATO Advanced Study Institute on
Plasma Assisted Decontamination of Biological and Chemical Agents (Springer, Cesme-Izmir,
Turkey, 2007), p. 173.
10. Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier
Discharge Plasma, S. Kalghatgi, M. Balasubramanian, G. Nagaraj, A.S. Wu, A.D. Brooks, G.
Fridman, M. Cooper, V. Vasilets, A. Gutsol, A. Fridman, G. Friedman, Blood, (ASH Annual Meeting
Abstracts) 2007, accepted.
11. Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier
Discharge,
S. Kalghatgi, G. Fridman, M. Cooper, G. Nagaraj, M. Peddinghaus, M.
Balasubramanian, V. Vasilets, A. Gutsol, A. Fridman, G. Friedman, In Abstracts and full papers
18th International Symposium on Plasma Science, Aug 26th-Aug31st, Kyoto University, Kyoto,
Japan : Kyoto University, 2007
12. Non-Equilibrium Dielectric Barrier Discharge Plasma Promoting Apoptotic Behavior in
Melanoma Skin Cancer Cells, G. Fridman, R. Sensenig, S. Kalghatgi, A. Shereshevsky, M.
Balasubramanian, A. Gutsol, V. Vasilets, A. Brooks, A. Fridman, G. Friedman, In Abstracts and full
papers 18th International Symposium on Plasma Science, Aug 26th-Aug31st, Kyoto University,
Kyoto, Japan : Kyoto University, 2007
13. Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier
Discharge Plasma, S. Kalghatgi, G. Fridman, M. Cooper, G. Nagaraj, M. Peddinghaus, M.
Balasubramanian, V. Vasilets, A. Gutsol, A. Fridman, G. Friedman, Proceedings of the 34th
International Conference on Plasma Science/16th Pulsed Power Plasma Symposium, Jun 16 – Jun
22nd 2007, Albuquerque, New Mexico. pp 1058-1063.
14. Use of Ferrofluid Patterns as Diffusion Masks, Derek Halverson, Ben Yellen, S. Kalghatgi, G.
Friedman, Proceedings of the Materials Research Society Spring Meeting, March 28- April 1 2005,
San Francisco.
POSTER PRESENTATIONS
1. Low Dose Non-Thermal Dielectric Barrier Discharge (DBD) Plasma Enhances Wound Healing
In An In Vitro Epithelial Cell Model, Oleg Alekseev, Sameer Kalghatgi, Gary Friedman, and Jane
Azizkhan-Clifford, Discovery Day 2009, Drexel University College of Medicine, Oct 7 2009,
Philadelphia, PA, USA. (Third prizewinner).
2. Cell Proliferation Following Non-Thermal Plasma is Related to Reactive Oxygen Species
Induced Fibroblast Growth Factor-2 Release, S. Kalghatgi, A. Fridman, G. Friedman, A. MorssClyne. Sep 2nd- Sep 6 2009, Minneapolis, Minnesota, USA.
3. Low Dose Non-Thermal Plasma Interacts with Mammalian Cells Indirectly through
Modification of the Cell Culture Medium, S. Kalghatgi, C. Kelly, E. Cerchar, A. Fridman, J.
Azizkhan-Clifford, G. Friedman, 19th International Symposium on Plasma Chemistry, Jul 26th - July
31st 2009, Bochum, Germany.
4. On the Interaction of Non-Thermal Atmospheric Pressure Plasma with Tissues, S. Kalghatgi,
C. Kelly, E. Cerchar, R. Sensenig, A. Brooks, A. Fridman, A. Morss-Clyne, J. Azizkhan-Clifford,
G. Friedman. 17th IEEE Pulsed Power Conference (PPC), Jun 29th - Jul 2nd 2009, Washington
D.C., USA
5. Toxicity of Direct Non-Thermal Atmospheric Pressure Plasma Treatment of Living Tissue,
S. Kalghatgi, D. Dobrynin, A. Wu, E. Podolsky, E. Cerchar, G. Fridman, A. Fridman, A. Brooks,
K. Barbee, G. Friedman. 17th IEEE Pulsed Power Conference (PPC), Jun 29th - Jul 2nd 2009,
Washington D.C.,
6. Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma Enhances
Endothelial Cell Proliferation Via Fibroblast Growth Factor-2 Release, S. Kalghatgi, A.
Fridman, G. Friedman, A. Morss-Clyne, 2009 Summer Bioengineering Conference, Jun 17th - 21st,
Lake Tahoe, CA, USA.
7. Mechanism of Induction of Apoptosis in Melanoma Cancer Cells by Non-Thermal Plasma, S.
Kalghatgi, E. Cerchar, G. Fridman, A. Shereshevsky, K. Arjunan, R. Sensenig, E. Podolsky, B.
Torabi, A. Fridman, A. Brooks, J. Azizkhan-Clifford, G. Friedman, 36th IEEE International
Conference on Plasma Science (ICOPS), May 29th - Jun 4th 2009, San Diego, California, USA.
8. Toxicity of direct Non-thermal Plasma Treatment of Living Tissue, D. Dobrynin, S. Kalghatgi,
G. Fridman, A. Wu, E. Podolsky, K. Barbee, A. Brooks, A. Fridman, G. Friedman, 36th IEEE
International Conference on Plasma Science (ICOPS), May 29th - Jun 4th 2009, San Diego,
California, USA.
9. Physical and biological mechanisms of plasma interaction with living tissue, G. Fridman, D.
Dobrynin, S. Kalghatgi, A. Brooks, G. Friedman, A. Fridman , 36th IEEE International Conference
on Plasma Science (ICOPS), May 29th - Jun 4th 2009, San Diego, California, USA.
10. Toxicity of Low Temperature Plasma Treatment of Living Tissue, D Dobrynin, S. Kalghatgi, G
Fridman, A Wu, E Podolsky, K Barbee, A Brooks, G Friedman, A Fridman, 2009 Drexel IEEE
Graduate Forum, Technical Poster Symposium, May 4, 2009, Philadelphia, USA.
11. Induction of Apoptosis by Non-thermal Plasma Treatment of Melanoma Cancer Cells, S.
Kalghatgi, K. Arjunan, R. Sensenig, E. Cerchar, E. Podolsky, G. Fridman, B. Torabi, A. Fridman, A.
Brooks, J. Azizkhan-Clifford, G. Friedman, 2009 Drexel University Research Day, April 23rd 2009,
Philadelphia, PA, USA.
12. Low Dose Non-Thermal Plasma Enhances Endothelial Cell Proliferation via Release of
Fibroblast Growth Factor, S. Kalghatgi, K. Arjunan, A. Fridman, G. Friedman, A. Morss Clyne.
2009 Drexel University Research Day, April 23 2009, Philadelphia, PA, USA.
13. Mechanisms of Interaction of Non-Thermal Atmospheric Pressure Dielectric Barrier
Discharge Plasma with Mammalian Cells, S. Kalghatgi, C. Kelly, E. Cerchar, K. Arjunan, A.
Fridman, J. Azizkhan-Clifford, G. Friedman, 2009 Drexel University Research Day, April 23rd 2009,
Philadelphia, PA, USA.
14. Toxicity of low temperature plasma treatment of living tissue, D Dobrynin, G Friedman, S.
Kalghatgi, G Fridman, A Wu, E Podolsky, K Barbee, A Brooks, A Fridman, 11th Annual Research
Day, April 23, 2009, Drexel University, Philadelphia, USA.
15. Biomedical applications of low temperature plasmas, D Dobrynin, S. Kalghatgi, G Fridman, A
Wu, E Podolsky, K Chakravarthy, K Barbee, A Brooks, S Murthy, Y Mukhin, G Friedman, A
Fridman, 11th Annual Research Day, April 23, 2009, Drexel University, Philadelphia, USA.
16. Mechanisms of Interaction of Non-Thermal Plasma with Mammalian Cells, S. Kalghatgi, C.
Kelly, E. Cerchar, A. Fridman, J. Azizkhan-Clifford, G. Friedman, 2nd International Conference on
Plasma Medicine (ICPM-2), Mar 16th – Mar 20th 2009, San Antonio, TX, USA
17. Induction of Apoptosis by Non-thermal Plasma Treatment of Melanoma Cells, S. Kalghatgi,
K. Arjunan, R. Sensenig, E. Cerchar, E. Podolsky, G. Fridman, B. Torabi, A. Fridman, A. Brooks, J.
Azizkhan-Clifford, G. Friedman, 2nd International Conference on Plasma Medicine (ICPM-2), Mar
16th – Mar 20th 2009, San Antonio, TX, USA
18. Non-Thermal Plasma Induces DNA Damage Through the Generation of Long-lived Reactive
Oxygen Species, S Kalghatgi, C Kelly, E Cerchar, R Sensing, K Priya-Arjunan, G Fridman, A
Fridman, G Friedman, J Clifford-Azizkhan, Drexel University College of Medicine Discovery Day,
October 15th 2008, Philadelphia, PA.
19. Induction of Apoptosis by Non-Thermal Plasma Treatment of Melanoma Cells, R Sensenig, S
Kalghatgi, E Cerchar, B Torabi, E Podolsky, K Priya-Arjunan, G Fridman, A Fridman, G Friedman,
A Brooks, J Clifford-Azizkhan, Drexel University College of Medicine Discovery Day, October 15th
2008, Philadelphia, PA.
20. Penetration of Non-Thermal Dielectric Barrier Discharge Plasma Into Living Cells, S.
Kalghatgi, C. Kelly, G. Fridman, J. Azizkhan-Clifford Azizkhan, G. Friedman, Gordon Research
Conference on Plasma Processing Science, Jul 13-18th 2008, Mt. Holyoke, South Hadley,
Massachusetts.
21. Physical and Biological Mechanisms of Plasma Interaction with Living Tissue, G Fridman, PI
Lelkes, K Barbee, D Dobrynin, M Cooper, H Ayan, VN Vasilets, A Gutsol, A Fridman, AD Brooks, A
Shereshevsky, R Sensenig, M Balasubramanian, P Zhu, BD Freedman, C Kelly, J Clifford, S
Kalghatgi, G Friedman, 2008 Gordon Research Conference (GRC) on Plasma Processing
Science, July 13-18, 2008, Mount Holyoke College, South Hadley, MA, USA.
22. Toxicity Analysis of Non-Thermal Plasma Treatment of Living Tissue, S. Kalghatgi, D.
Dobrynin, R. Sensenig, A. Wu, G. Fridman, K. Barbee, Dr. M. Balasubramanian, Dr. A. Brooks, A.
Fridman, G. Friedman, 35th IEEE International Conference on Plasma Science (ICOPS), June 1519 2008, Karlsruhe, Germany.
23. Toxicity of Non-thermal Plasma Treatment of Endothelial Cells, S. Kalghatgi, G. Fridman, A.
Fridman, G. Friedman, Alisa Morss-Clyne, 35th IEEE International Conference on Plasma Science
(ICOPS), June 15-19 2008, Karlsruhe, Germany.
24. Physical and Biological Mechanisms of Plasma Interaction with Living Tissue, G. Fridman, P.
Lelkes, K. Barbee, D. Dobrynin, M. Cooper, Halim Ayan, A. Gutsol, A. Fridman, A. Brooks, A.
Shereshevsky, R. Sensenig, M. Balasubramanian, Peimin Zhu, B. Freedman, C. Kelly, J. AzizkhanClifford, S. Kalghatgi, G. Friedman, 10th Annual Drexel University Research Day, April 22nd 2008,
Philadelphia, PA, USA
25. Treatment of Endothelial Cells by Non-Thermal Atmospheric Pressure Dielectric Barrier
Discharge Plasma, S. Kalghatgi, G. Fridman, A. Fridman, G. Friedman, Alisa Morss Clyne, 10th
Annual Drexel University Research Day, April 22nd 2008, Philadelphia, PA, USA
26. Penetration of Direct Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge
Plasma Treatment Into Living Cells, S. Kalghatgi, C. Kelly, G. Fridman, J. Azizkhan-CliffordAzizkhan, A. Fridman, G. Friedman, 10th Annual Drexel University Research Day, April 22nd 2008,
Philadelphia, PA, USA
27. Biomedical Applications of Low Temperature Plasmas, D. Dobrynin, G. Fridman, S. Kalghatgi,
A. Wu, R. Sensenig, M. Balasubramanian, K. Barbee, A. Brooks, G. Friedman, Valery Gostev, Yurii
Mukhin, A. Fridman, 10th Annual Drexel University Research Day, April 22nd 2008, Philadelphia, PA,
USA
28. Induction of apoptosis in Melanoma Cells by Non-Thermal Atmospheric Plasma Discharge,
R. Sensenig, S. Kalghatgi, G. Fridman, A. Shereshevsky, A. Brooks, V. Vasilets, A. Gutsol, A.
Fridman, G. Friedman, SSO's 61st Annual Cancer Symposium, March 13-16, 2008, Chicago. USA
29. Physical and Biological Mechanisms of Plasma Interaction with Living Tissue, G Fridman, D
Dobrynin, S Kalghatgi, M Cooper, A Shereshevsky, P Zhu, C Kelly, R Sensenig, H Ayan, PI
Lelkes, K Barbee, VN Vasilets, AD Brooks, M Balasubramanian, BD Freedman, J Clifford, G
Friedman, A Gutsol, A Fridman, IEEE Technical Poster Symposium, Drexel University,
Philadelphia, March 7, 2008.
30. Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier
Discharge Plasma, G. Nagaraj, S. Kalghatgi, A. Wu, G. Fridman, M. Cooper, M. Peddinghaus, M.
Balasubramanian, A. Brooks, V. Vasilets, A. Gutsol, A. Fridman, G. Friedman, American Society of
Hematology Annual Meeting, Dec 7-11, 2007. Atlanta. USA
31. Medical Applications of Floating Electrode Dielectric Barrier Discharge, G. Fridman, R.
Sensenig, A. Shereshevsky, L. Peddinghaus, M. Balasubramanian, M. Jost, A. Brooks, D.
Dobrynin, S. Kalghatgi, H. Ayan, M. Cooper, A. Fridman, A. Gutsol, V. Vasilets, G. Friedman, The
Translational Research in Biomedical Engineering Poster Competition, Drexel University,
Philadelphia, October 26, 2007.
32. Mechanism of Blood Coagulation by Non-Thermal (Cold) Atmospheric Pressure Dielectric
Barrier Discharge Plasma, S. Kalghatgi, G. Fridman, G. Nagaraj, M. Cooper, M.
Balasubramanian, A. Brooks, V. Vasilets, A. Gutsol, A. Fridman, G. Friedman, First International
Conference on Plasma Medicine (ICPM-1), October 15th - 18th, 2007, Corpus Christi, TX.
33. Sterilization of Living Human and Animal Tissue by Non-Thermal Atmospheric Pressure
Dielectric Barrier Discharge Plasma, G. Fridman, M. Cooper, D. Dobrynin, H. Ayan, A. Fridman,
A. Gutsol, V. Vasilets, S. Kalghatgi, G. Friedman, A. Shereshevsky, A. Brooks, M. Peddinghaus,
M. Balasubramanian, NATO Advanced Study Institute (ASI), Plasma Assisted Decontamination of
Biological and Chemical Agents, September 16-26, 2007, Çesme, Turkey.
34. Non-Equilibrium Dielectric Barrier Discharge Plasma Promoting Apoptotic Behavior in
Melanoma Skin Cancer Cells, G. Fridman, S. Kalghatgi, R. Sensenig, A. Shereshevsky, R.
Stoddard, G. Friedman, A. Gutsol, V. Vasilets, A. Fridman, A.D. Brooks, NATO Advanced Study
Institute (ASI), Plasma Assisted Decontamination of Biological and Chemical Agents, September
16-26, 2007, Çesme, Turkey.
35. Devices and Technological Aspects of Plasma-Medical Systems, G. Friedman, G. Fridman, H.
Ayan, S. Kalghatgi, A. Fridman, A. Gutsol, NATO Advanced Study Institute (ASI), Plasma Assisted
Decontamination of Biological and Chemical Agents, September 16-26, 2007, Çesme, Turkey.
36. Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier
Discharge Plasma, S. Kalghatgi, G. Fridman, M. Cooper, G. Nagaraj, M. Peddinghaus, M.
Balasubramanian, V. Vasilets, A. Gutsol, A. Fridman, G. Friedman, 18th International Symposium on
Plasma Chemistry, Aug 26th – Aug 31st 2007, Kyoto, Japan
37. Non-Equilibrium Dielectric Barrier Discharge Plasma Promoting Apoptotic Behavior in
Melanoma Skin Cancer Cells, G. Fridman, R. Sensenig, S. Kalghatgi, A. Shereshevsky, M.
Balasubramanian, A. Gutsol, V. Vasilets, A. Brooks, A. Fridman, G. Friedman, 18th International
Symposium on Plasma Chemistry, August 26 - 31, 2007, Kyoto, Japan.
38. Wound Sterilization and Promoted Healing using Non-thermal Atmospheric Pressure
Plasma, Charles Marine, G. Fridman, Mogeega Cooper, A. Fridman, A. Gutsol, V. Vasilets, S.
Kalghatgi, G. Friedman, STAR Scholars Program, Pennoni Honors College, Drexel University,
August 15th, 2007.
39. Floating Electrode Dielectric Barrier Discharge Initiates Apoptosis in Melanoma Skin Cancer
Cells, G. Fridman, S. Kalghatgi, R. Sensenig, A. Shereshevsky, Rick Stoddard, G. Friedman, A.
Gutsol, V. Vasilets, A. Fridman, A. Brooks, Drexel University Ninth Annual Research Innovation
Scholarship and Creativity (RISC) Day, April 17, 2007, Drexel University, Philadelphia, USA.
40. Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier
Discharge Plasma, S. Kalghatgi, M. Cooper, G. Fridman, Lisa Peddinghaus, G. Nagaraj, M.
Balasubramanian, V. Vasilets, A. Gutsol, A. Fridman, and G. Friedman, Drexel University Ninth
Annual Research Innovation Scholarship and Creativity (RISC) Day, April 17, 2007, Drexel
University, Philadelphia, USA.
41. Sterilization of Living Human and Animal Tissue by Non-Thermal Atmospheric Pressure
Dielectric Barrier Discharge Plasma, G. Fridman, M. Cooper, D. Dobrynin, Halim Ayan, A.
Fridman, A. Gutsol, V. Vasilets, S. Kalghatgi, G. Friedman, A. Shereshevsky, A. Brooks, M.
Peddinghaus, M. Balasubramanian, Drexel University Ninth Annual Research Innovation
Scholarship and Creativity (RISC) Day, April 17, 2007, Drexel University, Philadelphia, USA
42. On Anisotropic mobility of non-magnetic microspheres in Ferrofluid, S. Kalghatgi, Derek
Halverson, Mario Baden, Gennady Friedman, Drexel University Annual Research Day, April 2005
Drexel University, Philadelphia
43. Manipulation of Non-Magnetic Materials in Ferrofluid Containing Media, Derek Halverson, Ben
Yellen, S. Kalghatgi, Gennady Friedman, Drexel University Annual Research Day, April 2005
Drexel University, Philadelphia (Received a Honorable mention from the ECE Department).
PATENTS
1. Plasma treatment for growth factor release from cells and tissues. S. Kalghatgi, A. Fridman, G.
Friedman, Alisa Morss Clyne. March 16th 2009 - Patent electronically filed with the United States
Patent & Trademark Office (U. S. Provisional Patent Application Serial No. 61/160,496)
SKILLS
Laboratory Skills si/sh RNAi assays, Plasmid DNA extraction, Gel Electrophoresis, Immunoblotting
(Western Blots), ELISA’s, Cell Culture, Cell Proliferation and Migration Assays, Apoptosis (caspase
cleavage, TUNEL, Annexin V/PI), Colorimetric and Fluorometric 96-well plate reader assays, Flow
Cytometry, FACS analysis, Fluorescence Microscopy, Immunofluorescence, Cytotoxicity Assays, Lipid
Peroxidation Assays, Comet Assay, in-vivo animal studies (porcine models), FTIR-ATR, SEM.
Software Tools GraphPad Graphing & Statistics, Protein Quantification, Gel Imaging, MS Office,
MATLAB, PSpice, ImagePro.
Research Writing Journal and Conference manuscripts, IRB and IACUC protocols, grant proposals
and patents
LEADERSHIP ACTIVITIES AND SERVICE
Reviewer
IEEE Transactions on Plasma Science
10/2007 – Present
Treasurer
Graduate Student Association (GSA)
6/2008 – 6/2009
Responsible for allocating and managing a budget of $100,000 for all the daughter Graduate student
organizations spread over three different Drexel University campuses. Negotiated successfully with the
Drexel University to award 100% Health Insurance to all Full-Time PhD Students, Implemented a
campaign and fundraiser towards increasing awareness for recycling on campus, Oversight and
planning of Graduate Student Day handed over to the GSA in its entirety.
Vice President
Engineering Graduate Association (EGA)
6/2006 – 6/2008
Leader in a group of 500 engineering graduate students that promotes collaboration between
engineering departments. Organized various seminars, socials, outings and sporting events allowing
students to share research ideas, socialize in a large peer group and become actively involved in
various activities on campus.
Secretary
Engineering Graduate Association (EGA)
6/2005 – 6/2006
RESEARCH EXPERIENCE
A.J. Drexel Plasma Institute
Drexel University, Philadelphia PA
Research Fellow, PhD Candidate
4/2006 – Present
1. Investigated the induction of DNA damage by non-thermal plasma discharge in mammalian cells by
looking at the phosphorylation of H2AX, a DNA damage marker. Additionally, using RNA
interference, RT-PCR and molecular biology techniques, studied the ATM/ATR mediated DNA
repair pathways in response to DNA damage induced by non-thermal electrical plasma produced
reactive oxygen species (ROS).
2. Studied the mechanisms of Non-thermal plasma induced proliferation of endothelial cells using cell
proliferation and migration assays, flow-cytometry, to develop non-thermal plasma as a potential
novel therapy for growth factor initiated promotion or inhibition of endothelial cell mediated
angiogenesis, which is an important target for treating diseases in which there is either poor
vascularisation (chronic wounds) or abnormal vascularisation (malignancies).
3. Studied the induction of apoptosis in melanoma cancer cells by non-thermal plasma electrical
discharge by using Annexin-V/PI, Caspase cleavage and flow cytometry to develop non-thermal
plasma as a novel clinical device for cancer treatment.
4. Investigated the potential long term and short-term toxicity of non-thermal plasma on intact and
wounded animal model to develop non-thermal plasma as a potential clinical device for wound
sterilization and accelerated wound healing.
5. Studied the mechanism of blood coagulation by non-thermal atmospheric pressure dielectric barrier
discharge to evaluate the use of non-thermal plasma as a potential wound healing device in a
clinical or battlefield setting.
Drexel University, Philadelphia PA
Research Fellow, PhD Candidate
10/2005 – 4/2006
1. Studied the anisotropic mobility of non-magnetic spheres in ferrofluid for biotechnological
applications like drug delivery, imaging, etc by tracking the motion of nonmagnetic microspheres
immersed in ferrofluid under the influence of a uniform external magnetic field.
Drexel University, Philadelphia PA
Graduate Research Assistant
4/2005 – 9/2005
1. Performed analytical modeling of NMR signal generated by solenoidal microcoil catheters using
MATLAB® and elliptical integrals. Characterized the magnetic fields generated by axisymmetric
solenoids as a tool for NMR spectroscopy.
TEACHING EXPERIENCE
Drexel University, Philadelphia PA
Teaching Assistant
1/2006 – Present
Electrical Engineering Department: Taught undergraduate level engineering courses at Drexel
University Electrical and Computer Engineering Department. My primary role was to conduct lab
sessions, hold recitations, grade home works, quizzes and lab reports, and teach a few lectures for the
following courses
Fundamentals of Intelligent Systems (Winter 06, Spring 06); Transform Methods and Filtering
(Winter 07); Electronic Devices (Spring 07, Fall 07); Laboratory 4 (Summer 07, Winter 08,
Summer 08); Laboratory 1 (Spring 08); Electromagnetic Fields and Waves (Fall 08); Laboratory 2
(Winter 09); Solid State Devices (graduate course) (Fall 09).
PROFESSIONAL MEMBERSHIPS
Institute of Electrical and Electronic Engineers (IEEE)
American Association for Advancement of Science (AAAS)
Founding member of the International Society of Plasma Medicine (ISPM)
June 2004 – Present
Jan 2008 – Present
Mar 2009