sedimentation rate, or physician global assessment), lasting for at least two months after the treatment period. Collageena Can Do More For Patients Who Need More Naturally SIXTY PERCENT of the patients showed substantial clinical response and one patient showed a complete response in which the disease was totally eliminated for 26 months. More importantly, there were absolutely no side effects. The Natural First choice for Reduction of Inflammations, Body Pains and Joints Discomfort Medical research from Harvard (USA) and Rostock (Germany) Universities confirms that Collagen supplementation reduces body pain and inflammation associated with muscles and joints naturally. Collageena is one of the most digestible, bioavailable and pleasant tasting forms of collagen available today. Collageena added to one's diet increase the body’s ability to regenerate collagen that is reduced with age. The Collageena formula has also shown good results in curbing appetite, boosting energy and endurance, as well as improving skin and muscle tone. All patients were evaluated. Twenty-eight had received the collagen type II and 31 had received the placebo. Compared to the placebo group, the collagen type II group showed significant improvements in joint swelling, tenderness or pain. Harvard University School of Medicine By Alex Duarte, O.D., Ph.D. At Harvard University School of Medicine, Dr. David Trentham and his colleagues gave very small doses of solubilized collagen type II to 10 patients with rheumatoid arthritis. These patients had all immunosuppressive drugs and anti-inflammatories such as methotrexate and mercaptopurine removed before they took the collagen type II. Patients took small doses of collagen type II for one month and then increased the dosage for two months thereafter. The dosage was determined through the various animal studies that had determined specific concentrations. The clinical response was defined as a 50% or greater improvement in the number of swollen and tender joints, accompanied by a 50% or greater improvement in two additional measures (morning stiffness, 15 meter walking time, grip strength, Westergren erythrocyte This also included the degree of swelling and tenderness together. The doctors evaluated the response in a 15 meter walking time at months one, two and three. During the period at which the patients were taken off Four patients in the collagen type II group went into the next realm of the almost unbelievable, and showed a complete resolution of the disease. The Harvard Study was sponsored by Autoimmune, a Lexington, Massachusetts biotechnology company. Only highly purified chicken sternal collagen type II was used. This report from the book entitled "The Collagen Type II Cure for Arthritis and Heart Disease", by Alex Duarte, O.D., Ph.D. Published October 1997, ISBN # 1-891036-11-4 The Effects of Collagen Hydrolysat on Symptoms of Chronic Fibromyalgia and Temporomandibular Joint Pain Gary B. Olson, D.D.S.; Sue Savage. M.B.S. JoAnn Olson, R.P.P. ABSTRACT: Twenty (20) people who had medically diagnosed fibromyalgia for two to 15+ years participated in and completed a 90-day evaluation to determine effects of collagen hydrolysat on symptoms of chronic fibromyalgia, with twelve reporting temporomandibular joint pain. Participants were evaluated initially and then at 30-, 60-, and 90-day periods. Final results were obtained and comparisons made. The average pain complaint levels decreased significantly in an overall group average, and dramatically with some individuals. It was concluded that patients with fibromyalgia and concurrent temporomandibular joint problems may gain symptomatic improvement in their chronic symptoms by taking collagen. The total without a response of less pain in forty-five days was three or appox. 10.1% and only one placebo subject recorded a response in forty-five days. Side effects - Only one subject had nausea. It was noted that he was on other medications as well. CONCLUSION Collagen Type II treatment had a significant effect on subjective pain syndromes. Most subjects responded to Collagen Type II in the first 21 days of the trial. Many of these pained subjects had previously been on long-term, pharmaceutical treatment programs. Many subjects responded by initiating life style changes due to lack of pain. Many were excited by the increase in their daily activity. The results have prompted the authors to develop specific disease/pain syndrome trials in the near future. The Journal of Cranomandibular Practice April 2000, vol 18, no 2. Clinical studies show: Hydrolyzed Collagen can relieve osteoarthritic pain The first well-founded studies were carried out during the 1980s [1; 2; 3 etc.]. Already in 1991, we published data from our own randomized, double-blind study on 81 patients suffering from osteoarthritis . Rippe et al. show: Hydrolyzed collagen influences isokinetic power The results of a double-blind, randomized, prospective and placebo-controlled study carried out by James Rippe and colleagues (Massachusetts, USA) on 190 patients with confirmed osteoarthritis of the knee are of high importance, too  Clinical studies demonstrate: Hydrolyzed collagen can improve mobility and reduce the requirement for analgesics BEUKER and ROSENFELD  in a 6-month placebo-controlled study on 100 elderly patients (average age 62) also established a distinct therapeutic effect. ■ There are no medical application restrictions on hydrolyzed collagen Hydrolyzed collagen, a protein prepared by hydrolysis and which is contained in high proportions in foodstuffs of animal origin is highly tolerated and without side-effects. TAKEDA  ■ Collagen is well digested and absorbed ■ Hydrolyzed collagen has an effect on other collagen-rich vital tissues In veterinary medicine, the highly significant improvement in the properties of hair and hooves brought about by hydrolyzed collagen has been known for many years (e.g. MORGANTI ; BRODIE  ■ Hydrolyzed collagen causes no serious intolerance reactions  References 1. Krug E.; Acta Medica Empirica 28: 1-23; 1979 2. Götz B.; Ärztliche Praxis 34: 3130-34; 1982 3. Oberschelp U., Seeligmüller K. et al.; Therapiewoche 39: 3153-57; 1989 4. Adam, M.; “Welche Wirkung haben Gelatinepräparate?” in: Therapiewoche 41: 2456-61; 1991 5. Seeligmüller K. et. al.; Therapiewoche 39: 3153-57; 1989 6. Seeligmüller K. et al.; Therapiewoche 4: 1810-13; 1993 7. Beuker F. et al; Int J Sportsmed 1: 1-88 ; 1996 8. Moskowitz R.; Semin Arthritis Rheum 30: 87-99; 2000 9. 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