Curriculum Vitae
Dr. Kalsoom Akhtar
Principal Scientist
National Institute for Biotechnology and Genetic Engineering POBox_577, Jhang Road, Faisalabad, PAKISTAN.
Tel: off:(92-41) 2651475 - 79: Res:041-8817608
Email:kkhalid@nibge.org
PERSONAL PARTICULARS
Date Of Birth:
Nationality:
Postal Address:
01- 01-1967 (Faisalabad, Pakistan)
Pakistani
P.O. Box No. 577, NIBGE, Faisalabad, Pakistan.
Tel: +92-41- 2651475 -79
ACADEMIC RECORD
PhD (Chemistry) University of the Punjab, Lahore, Pakistan (2008)
M.Sc (Chemistry) Quaid-i-Azam University Islamabad (1989)
B.Sc. Punjab University, Pakistan (1986)
F.Sc. Federal Board of Intermediate and Secondary Education, Islamabad (1984).
EXPERIENCE & EXPERTISE
Two and a half years research experience on synthesis of organic resins at Applied Chemistry Division
(ACD), PINSTECH, Nilore Islamabad.
About twenty years research experience in the field of bioprocessing of ores and fossil fuels. Working as
Principal Scientist and group leader of “Bioprocessing of ores and fossil fuels” group at Industrial
Biotechnology Division of National Institute for Biotechnology & Genetic Engineering (NIBGE),
Faisalabad, Pakistan. Research interests include microbiological bioaccumulation of heavy
metals/radionuclides for development of bioseparation and bioremediation processes for industrial
effluents, bioleaching of precious/heavy metals from low grade ores and biodesulfurization of fossil fuels
especially coal, biosynthesis & biotransformations of bio-active compounds.
Extensive experience of working on Atomic Absorption Spectrophotometer (AAS), Elemental Analyser
(CHNS/O), Fourier transform infrared spectrometer (FTIR), HPLC, Polymerase Chain Reaction (PCR),
Gel Electrophoresis, PGSTAT12, and Chromatographic techniques. Also contribute in providing quality
control analytical services to other agencies in the field of textile product, food and water analysis.
RESEARCH SUPERVISION/CO-SUPERVISION
M.Sc
Co-supervised following M. Sc. students to carry out research work for their theses.
1.
Effect of chemical pre-treatments on lead biosorption by using Trichoderma harzianum. Ms.
Sadaf Javeed, GC University, Faisalabad, Session 2003-2005.
2.
Optimizing zinc removal from aqueous solution by filamentous fungus Trichoderma
harzianum. Ms Mudassir Jabeen, GC University, Faisalabad, Session 2003-2005.
3.
Biosorption of cadmium from aqueous solution by dead Trichoderma harzianum. Ms Aisha
Saddiqa , GC University, Faisalabad, Session 2003-2005.
M.Phil
Co-supervised following M. Phil. students to carry out research work for their theses.
1.
Application of RAPD for Genomic Analysis of Different Strains of Thiobacilli and their
Kinetic Studies. Ms Tanveer Akbar, University of Quaid-i-Azam, Session 1999-2000.
2.
Studies on Biosynthesis of Tylosin Using Streptomyces fradiae NRRL-2702. Ms Aqueela
Sharif, University of Quaid-i-Azam, Session 2000-2001.
3.
Hyper Production of Tylosin by Streptomyces fradiae NRRL-2702 through genetic
manipulations. Ms Riffat Tahira, University of Quaid-i-Azam, Session 2001-2003.
4.
Stability Studies of Immobilized Glucose Oxidase for Glucose Biosensor Fabrication. Mr.
Sakandar Raouf, University of Quaid-i-Azam, Session 2002-2004.
5.
Construction of fungal RNAi vector for silencing of cahB gene in fungus Acremonium
chrysogenum. Mr. Muhammad Muddassar, University of Quaid-i-Azam, Session 2003-2005.
6.
Development of enzyme biosensor employing different matrices.
University of Quaid-i-Azam, Session 2003-2005.
7.
Immobilization of Salmon sperm DNA on glassy carbon electrode and its applications to
study the drug-DNA interaction. Mr Haq Nawaz, University of Quaid-i-Azam, Session 20042006.
8.
Irradiation mutagenesis of wild Streptomyces fradiae (NRRL 2702) for hyper production of
tylosin. Ms. Ruqia Iqbal, University of Quaid-i-Azam, Session 2004-2006.
9.
Effect of pH on electrochemical characterization of Tylosin-DNA interaction. Ms. Farah
Majeed, University of Quaid-i-Azam, Session 2005-2007.
10.
Optimization of process parameters for tylosin production using solid state fermentation by
wild type Streptomyces fradiae NRRL-2702 and its gamma irradiated mutant. Ms. Nosheen
Rasheed, University of Quaid-i-Azam, Session 2005-2007.
11.
Development and optimization of analytical technique to study the interaction of various
drugs with DNA biosesor. Ms Bushra Rafique, GC University Faisalabad, 2009.
12.
Effect of pretreatments on biosorption of lead by Trichoderma harzianum. Ms Nabeela
Saleem, PIEAS, Islamabad, Session 2009-2011.
Ms Ayesha Ihsan,
PUBLICATIONS:
Citations given below against each publication have been taken from following links:
ISI Web of Science (http://portal.isiknowledge.com/portal.cgi?DestApp=WOS&Func=Frame),
2
Science Direct (http://www.sciencedirect.com)
Google Scholar (http://scholar.google.com/scholar?q=GHAURI+MA*&ie=UTF-8&oe=UTF8&hl=en&btnG=Search)
PAPERS PUBLISHED IN REFEREED INTERNATIONAL JOURNALS
1.
Hasan M., Rashid N., Akhtar K., Osman S., Malik F. and Duddeck H 1992. Preparation,
separation and NMR spectral peak assignement of regioisomeric unsymmetrical benzimidazoles.
Journal of the Chemical Society of Pakistan 14 (1) 54-59 (Impact Factor 1.377, Citation 4,
MAR 1992)
2.
Hasan M., Rashid N., Akhtar K., Osman S., Malik F. and Duddeck H. 1993. Preparation,
separation and 1H NMR spectral peak assignement to some regioisomeric unsymmetrical
benzimidazoles. Revue Roumaine De Chimie, 38(6), 711-718 (Impact Factor 0.418, Citation
3, JUN 1993)
3.
Ahmad Z.., Ghauri M. A., Anwar M. A., Iqbal M., Rehman M., Akhtar K. and Khalid A. M.
2002. Transformations of plasmids of Acidithiobacillus ferrooxidans encoding ampicillin
resistanc to Escherichia coli strain DH5 for detecting copper tolerance genes on such plasmids.
Resource and Environ. Biotech. 3: 185-191(Citation 4)
4.
Akbar T., Akhtar K., Ghauri M. A., Anwar M. A., Rahman M., Rehman M., Zafar Y. and Khalid
M. A. 2005. Relationship among acidophilic bacteria from diverse environments as determined
by randomly amplified polymorphic DNA analysis (RAPD). World Journal of Microbiology and
Biotechnology 21(5): 645-648 (Impact Factor 1.532, Citation 4, Published: JUL 2005)
5.
Rauf S., Gooding J. J., Akhtar K., Ghauri M. A., Rahman M., Anwar M. A. and Khalid A. M.
2005. Electrochemical approach of anti-cancer drugs-DNA interaction. Journal of Pharmaceutical
and Biomedical Analysis. 37 (2), 205-217 (Impact Factor 2.967, Citation 109, Published FEB
23 2005)
6.
Rauf S., Ihsan A., Akhtar K., Ghauri M.A., Rahman M., Anwar M. A. and Khalid A. M. 2006.
Glucose oxidase immobilization on a novel cellulose acetate-polymethylmethacrylate membrane.
Journal of Biotechnology 121(3), 351-360 (Impact Factor: 3.045, Citation: 51, Published:
FEB 10 2006)
7.
Nawaz H., Rauf S., Akhtar K. and Khalid A. M. 2006. Electrochemical DNA biosensor for the
study of Ciprofloxacin-DNA interaction. Analytical Biochemistry 354 (1), 28-34. (Impact
Factor: 2.996, Citation: 20, Published: JUL 1 2006)
8.
Rauf S., Nawaz H, Akhtar K., Ghauri M.A and Khalid A. M. 2007. Studies on sildenafil citrate
(viagra) interaction with DNA using electrochemical DNA biosensor. Biosensors and
Bioelectronics 22 (11), 2471-2477. (Impact Factor: 5.602, Citation: 15, Published: MAY 15,
2007)
3
9.
Akhtar K., Akhtar M. W. and Khalid A. M. 2007. Removal and recovery of uranium from
aqueous solutions by Trichoderma harzianum. Water Research 41 (6), 1366-1378. (Impact
Factor 4.865, Citation: 40, Published: MAR 2007)
10.
Hanif M. A., Nadeem R., Nadeem M., Akhtar K. and Bhatti H. N. 2007. Kinetic studies for Ni
(II) biosorption from industrial wastewater by Cassia fistula (Golden Shower) biomass. J. Hazard.
Mater. 145 (3), 501-505. (Impact Factor: 4.173, Citation: 34, Published: JUL 16, 2007)
11.
Nasir M. H., Nadeem R., Akhtar K., Hanif M. A. and Khalid A. M. 2007. Efficacy of modified
distillation sludge of rose (Rosa centifolia) petals for lead(II) and zinc(II) removal from aqueous
solutions. J. Hazard. Mater. 147 (3), 1006-1014. (Impact Factor: 4.173, Citation: 34,
Published: AUG 25, 2007)
12.
Munawar N., Anwar M.A., Saleem M., Ghauri M. A. and Akhtar K. 2007. Biodepyritization of
indigenous coal using acidophilic mesophilic and moderately thermophilic bacteria. Pakistan
Journal of Zoology 39 (3), 147-151. (Impact Factor: 0.338, Citation: 0, Published: 2007)
13.
Akhtar, N., Ghauri, M. A., Iqbal, A., Anwar, M. A. and Akhtar, K., 2008. Biodiversity and
phylogenetic analysis of culturable bacteria indigenous to Khewra salt mine of Pakistan and their
industrial importance. Brazilian Journal of Microbiology 39 (1), 143-150. (Impact Factor:
0.896, Citation: 4, Published: JAN-MAR, 2008)
14.
Akhtar K., Akhtar M. W. and Khalid A. M. 2008. Removal and recovery of zirconium from its
aqueous solution by Candida tropicalis. J. Hazard. Mater. 156 (1-3), 108-117 (Impact Factor:
4.173, Citation: 7, Published; AUG 15, 2008)
15.
Khaliq S., Akhtar K., Ghauri M. A., Iqbal R., Khalid A. M. and Mudasssar M. 2009. Change in
colony morphology and kinetics of tylosin production after UV and gamma irradiation
mutagenesis of Streptomyces fradiae NRRL-2702. Microbiological Research 164, 469-477
(Impact Factor: 2.308, Citation: 6, JULY 15, 2009)
16.
Rehman M., Anwar M. A., Iqbal M., Akhtar K., Khalid A. M., Ghauri M. A. 2009. Bioleaching
of high grade Pb-Zn ore by mesophilic and moderately thermophilic iron and sulphur oxidizers.
Hydrometallurgy 97 (1-2) 1-7. (Impact Factor: 2.027, Citation: 2, Published: JUN, 2009)
17.
Akhtar K., Khalid A. M, Akhtar M. W. and. Ghauri M. A. 2009. Removal and recovery of
uranium from aqueous solutions by Ca-alginate immobilized Trichoderma harzianum.
Bioresource Technology 100, 4551-4558. (Impact Factor: 4.980, Citation: 18 Published: MAY
24, 2009)
Nadeem R., Ansari T. M., Akhtar K. and Khalid A. M. 2009. Pb(II) sorption by pyrolysed
Pongamia pinnata pods carbon (PPPC). Chemical Engineering Journal 152, 54-63. (Impact
Factor: 3.461, Citation: 4, published: 2009)
18.
19.
Khaliq S., Rashid N., Akhtar K. and Ghauri M. A. 2009. Production of tylosin in solid state
fermentation by Streptomyces fradiae NRRL-2702 and its gamma irradiated mutant (γ-1). Letters
in Applied Microbiology 49, 635-640. (Impact Factor: 1.622, Citation: 0, Published: JUN,
2009)
4
20.
Akhtar N., Ghauri M. A. Anwar M. A. Akhtar K. 2009. Analysis of the dibenzothiophene
metabolic pathway in a newly isolated Rhodococcus spp. FEMS Microbiology Letters 301, 95102. (Impact Factor: 2.044, Citation: 2, Published: JUN, 2009)
21.
Jamil M. S., Nadeem R., Hanif M. A., Ali M. A. and Akhtar K. 2010. Proximate composition
and mineral profile of eight different unstudied date (Phoenix dactylifera L.) varieties from
Pakistan. African Journal of Biotechnology 9(22), 3252-3259. (Impact Factor: 0, Citation: 1,
Published: May 2010)
22.
Haider R., Ghauri M. A., SanFilipo J. R., Jones E. J., Oremb W. H., Tatu C. A., Akhtar, K. and
Akhtar N. 2012. Fungal degradation of coal as a pretreatment for methane production. FUEL (In
press) (Impact Factor: 3.248)
23.
Aftab K., Akhtar K., Jabbar A., Rana S. M., Samoor Y. and Ghauri M. A. 2012. Process
optimization and mechanistic studies of lead (II): Aspergillus caespitosus interaction for
industrial effluent treatment. African Journal of Biotechnology (In press)
PAPERS PUBLISHED IN INTERNATIONAL PROCEEDINGS
1.
Khalid A. M., Anwar M. A., Shemsi A. M., Niazi G. and Akhtar K. 1993. Biohydrometallurgy
of low-grade carbonate bearing sandstone uranium ore. pp. 285-292. In: Torma, A. E., Apel M. L.
and Brierley, C. L. (eds) Biohydrometallurgical Technologies, Volume I, The Minerals, Metals
and Material Society, Pennsylvania, USA. (Citation 3)
2.
Khalid A. M., Ashfaq S. R., Bhatti T. M., Anwar M. A., Shemsi A. M. and Akhtar K. 1993. The
uptake of microbially leached uranium by immobilized microbial biomass. pp. 299-307. In:
Torma, A. E., Wey, J. E., and Lakshmanan, V. I. (eds). Biohydrometallurgical Technologies,
Fossil Energy, Materials, Bioremediation, Microbial Physiology, Volume II, The Minerals,
Metals, and Materials Society, Pennysylvania, USA. (Citation 3)
3.
Khalid A. M., Shemsi A. M., Akhtar K. and Anwar M. A. 1993. Uranium biosorption by
Trichoderma harzianum entrapped in polyester foam beads. pp. 309-317. In: Torma, A. E., Wey,
J. E., and Lakshmanan, V. I. (eds). Biohydrometallurgical Technologies, Fossil Energy,
Materials, Bioremediation, Microbial Physiology, Volume II, The Minerals, Metals, and
Materials Society, Pennysylvania, USA. (Citation 5)
4.
Khalid A. M., Anwar M. A., Shemsi A. M. and Akhtar K. 1993. Genetic manipulation of iron
and sulfur oxidizing bacteria for biohydrometallurgical operations. pp. 629-634. In: Torma, A.
E., Wey, J. E., and Lakshmanan, V. I. (eds). Biohydrometallurgical Technologies, Fossil Energy,
Materials, Bioremediation, Microbial Physiology, Volume II, The Minerals, Metals, and
Materials Society, Pennysylvania, USA. (Citation 1)
5.
Khalid A. M., Ghauri M. A., Anwar M. A., Akhtar K., Shemsi A. M., Bhatti T. M. and Iqbal M.
1995. Role of biotechnology for minerals and fossil fuels in the sustainable development of
Pakistan. In: Proceeding of International Symposium on Biotechnology for Sustainable
Development (Eds. K. A. malik, A. Nasim and A. M. Khalid), held on Dec. 15-20, 1993. pp. 309318.
5
6.
Khalid A. M., Anwar M. A., Shemsi A. M., Niazi G., Akhtar K., Bhatti T. M. and Malik K. A.
1995. Studies on bioleaching of uranium from low-grade sandstone uranium ore. pp.153-164: In:
Nuzhat Ahmed, Muhammad Ishaq, Obaid Yusuf Khan and Farzana Sarwar (eds) Biotechnology
or Environment and Agriculture. Centre for Molecular Genetics, University of Karachi, Karachi
75270, Pakistan.
7.
Raouf S., Akhtar K., Rahman M., Anwar M. A., Ghauri M. A. and Khalid A. M. 2003. Current
status of interaction of anticancer drugs with DNA: an electrochemical approach. Proceeding of
International conference on “Current trends in Radiopharmaceuticals”, jointly organized by
PINSTECH and NORI Islamabad, Pakistan. Nucleus (In press)
PAPERS PUBLISHED IN NATIONAL JOURNALS
1.
Ghauri M. A., Iqbal M., Anwar M. A., Shemsi A. M., Akhtar K. and Khalid A. M. 1998. Iron
oxidation at varied pH-values by Thiobacillus ferrooxidans-A potential bacterium in
bioremediation processes. Biologia, 44(1&2): 95-100.
PAPERS PUBLISHED IN NATIONAL PROCEEDINGS
1.
Shemsi A. M., Akhter K., Anwar M. A. and Khalid A. M. 1995. Removal and recovery of
uranium by modified fungus MTH-4. pp. 133-136. In: Ahmad N., Khan, A. Y., Jaffar, M.,
Subhani, M. S., Khan, N. and Ansari, F. L. (eds). Proceedings of Fifth National chemistry
Conference, 25-28 October, 1993. Quiad-i-Azam University, Islamabad, Pakistan.
2.
Anwar M. A., Qamar M. A., Akhtar K., Ghauri M. A. and Khalid A. M. 1995. Microbial
Demineralization of Coal. pp. 84-86. In: Ahmad N., Khan, A. Y., Jaffar, M., Subhani, M. S.,
Khan, N. and Ansari, F. L. (eds). Proceedings of Fifth National chemistry Conference,25-28
October, 1993. Quiad-i-Azam University, Islamabad, Pakistan.
3.
Ghauri M. A., Anwar M. A., Iqbal M., Akhtar K., Shemsi A. M., Niaz L. and Khalid A. M.
1997. New frontiers of biotechnology for minerals and fossil fuels. pp 168-178: Proceedings of
First Biotechnology Symposium held at Centre for Agricultural Biochemistry and Biotechnology,
University of Agriculture, Faisalabad on June 27, 1996 (Iqrar, A. Khan and Tanwir, A. Malik,
eds.,).
Ghauri M. A., Anwar M. A., Iqbal M., Akhtar K., Shemsi A. M. and Khalid A. M. 2001.
Physiological diversity amongst acidophilic bacteria isolated from geochemical extreme habitats.
In: Biohorizons- Biochemistry and Biotechnology: its role and need in the 21st century (Jamil, A.
and Sheikh, M. A. eds), Proceedings of Ist SESCOB Conference held at University of Agriculture
Faisalabad, Pakistan, Vol 2: 1-4.
4.
5.
Sajjad A., Ghauri M. A., Akhtar N. and Akhtar K. 2006. Recovery of integrons from manmade
and natural environments. pp 19-28. Proceedings of twenty sixth Pakistan Congress of Zoology,
University of the Punjab, Lahore on April 4-6, 2006.
ABSTRACTS PUBLISHED IN REFEREED INTERNATIONAL PROCEEDINGS/ABSTRACT
BOOKS
Total numbers
45
6
TECHNICAL REPORTS
1.
Ghauri M. A., Anwar M. A., Rehman M., Akhtar K. and Khalid A. M. 2002. Studies on
biodiversity of Extremophiles and their use in bioprocess technology. Final Report Submitted to
TWAS, Trieste, Italy
2.
Anwar M. A., Ghauri M. A., Rehman M., Akhtar K. and Khalid A. M. 2002. Upgradation of
high sulfur Pakistani coals through biotechnological process. Final Report Submitted to TWAS,
Trieste, Italy
3.
Khalid A. M, Akhtar K., Shemsi A. M. and Malik K. A. (1996). Radionuclide immobilization
by biosorption on microbial biomass. pp. 9. Report no. NIBGE/BMFF-5/IAEA8617RB(I)/1996.
Sumbitted to IAEA, Vienna.
TEAM
MEMBER/P.I.
OF
THE
RESEARCH
NATIONAL/INTERNATIONAL AGENCIES
1.
Title of the project
P. I.
Participation
Funding Agency
Allocated Amount
Status
2.
Title of the project
GRANTS
AWARDED
Radionuclide immobilization by biosorption on microbial
biomass
Dr. Ahmad M. Khalid
As a research team member
International Atomic Energy Agency
US $ 10,000.00
Completed
P. I.
Participation
Funding Agency
Allocated Amount
Bacterial leaching of metals from ores and establishment
of Pak-Kazakh analytical laboratory.
Dr. Ahmad M. Khalid
As a research team member
Ministry of Science and technology
Rs. 21.0 millions
3.
Title of the project
P. I.
Participation
Funding Agency
Allocated Amount
Status
Biodesulfurization of indigenous fossil fuels.
Dr. Ahmad M. Khalid
As a research team member
Ministry of Science and Technology (MoST)
Rs. 28.8 millions
In progress
4.
Title of the project
Development of hyper producer Cephalosporin C
producing strain of Acremonium chrysogenum by RNA
interference technique.
Kalsoom Akhtar
Pakistan Science Foundation
Rs. 0.9484 millions
In progress
P. I.
Funding Agency
Allocated Amount
Status
7
BY
5.
Title of the project
Genetic manipulations of mutation that leads to
hyperproduction of tylosin from Streptomyces fradiae NRRl2707 and development of Solid State Fermentation (SSF)
process using that mutant
Kalsoom Akhtar
International Foundation of Science
$ 6000. 0
Completed
P. I.
Funding Agency
Allocated Amount
Status
6.
Title of the project
Biotechnological applications of microorganisms in
bioleaching and bioremediation of metals
Dr. Muhammad Afzal Ghauri
Mrs. Kalsoom Akhtar
Higher Education Commission
Rs. 3.598927 millions
In progress
P. I.
Co. P.I.
Funding Agency
Allocated Amount
Status
JOURNAL CITATION REPORT (JCR) IMPACT FACTOR & CITATIONS
Impact Factor:
Citations:
56.245
362
8