DISTRIBUTED BY: Josef Gas.
MATERIAL SAFETY DATA SHEET
PRODUCT IDENTIFIER:
NITROUS OXIDE
Product Name(s):
NITROUS OXIDE
Formula:
Synonym(s):
LAUGHING GAS
Chemical Family: OXIDE OF
NITROGEN DINITROGEN
OXIDE
PRODUCT USE(S):
Anaesthesia in controlled hospital
condition. As oxidizer for analytical
W.H.M.I.S. Classification
Class(es): A, C, D2A
HAZARDOUS INGREDIENTS:
INGREDIENT
PARAMETERS
C.A.S. / P.I.N.
NUMBER(S)
CONC. %
VOL./VOL.
L.D. 50
L.C. 50
(Species & Route) (Species & Route)
NITROUS OXIDE
10024972/1070
APPR. 100 TDLo 24mg/kg
(2 hrs inhl-hum.)
PHYSICAL DATA
PHYSICAL STATE:
Gas @ N.T.P.
ODOUR AND APPEARANCE:
Colourless and Odourless
ODOUR THRESHOLD:
NONE
SPECIFIC GRAVITY (air=1):
1.530 (air=1)
VAPOUR PRESSURE:
5,074 kPa (736 psig) @ 21.1oC/70 oF
VAPOUR DENSITY:
1.812 kg/m3
EVAPORATION RATE:
Rapid
BOILING POINT:
-88.5oC
FREEZING POINT:
-90.8oC
pH:
Not Applicable
COEFFICIENT OF WATER/OIL DISTRIBUTION: Not Applicable
SOLUBILITY IN WATER:
58.8 cm3 / 100 cm3
% VOLATILES:
100
N2O
NOT APPL.
FOR TRANSPORT EMERGENCY CALL COLLECT CANUTEC TEL: 1-613-996-6666
UYI 111-1
FIRE OR EXPLOSION HAZARDS
CONDITIONS OF FLAMMABILITY:
MEANS OF EXTINCTION:
FLASH POINT:
UPPER FLAMMABLE LIMIT: NONE
AUTOIGNITION TEMPERATURE:
HAZARDOUS COMBUSTION PRODUCTS:
SENSITIVITY TO MECHANICAL IMPACT:
SENSITIVITY TO STATIC DISCHARGE:
SPECIAL PROCEDURES:
NONE. Nitrous Oxide will support and sustain combustion of other
materials. Some materials that do not burn in air may ignite in
presence of N2O.
Cool containers with water spray. Extinguish surrounding fires. N2O
will not burn but it will sustain the combustion of surrounding
materials.
NONE
NONE
LOWER FLAMMABLE LIMIT: NONE
NONE
NONE
NONE
NONE
Evacuate areas where a leak or a spill is present. Fight surrounding
fires as the case may be. Do not use water on the source of leak to
avoid ice formation that may obstruct the operation of Safety Relief
Devices.
REACTIVITY DATA
CONDITIONS OF CHEMICAL UNSTABILITY:
INCOMPATIBILITY:
CONDITIONS OF REACTIVITY:
HAZARDOUS DECOMPOSITION PRODUCTS:
NONE
All combustible, organic material, All reducing agents. Alkali metals.
N2O mat react readily with organic compounds.
NO, NO2.
TOXICOLOGICAL PROPERTIES
ROUTE OF ENTRY
SKIN (CONTACT):
SKIN (ABSORPTION):
EYE CONTACT:
INHALATION:
INGESTION:
YES
NO
YES
YES
NO
EFFECTS OF ACUTE EXPOSURE:
Exposure to N2O at 10% may induce analgesia (reduce sensitivity to pain), at higher concentration euphoria, loss of
Coordination and loss of consciousness may occur. At concentrations approaching 100% respiratory arrest may occur.
At concentrations approaching 100% respiratory arrest may occur due to the lack of oxygen, followed by death.
Therapeutic uses of N2O should be supervised by competent medical personnel.
EFFECTS OF CHRONIC EXPOSURE:
Prolonged occupational exposure of abuse has resulted in neurologic effects such as loss of pain, balance, impotence,
Reduction in motor and audiovisual skills. Recovery may occur in months but damages may be permanent. Kidney and
liver disorders have been reported along with fetal malformations and spontaneous abortions.
EXPOSURE LIMITS:
IRRITANCY:
SENSITIZATION:
CARCINOGENICITY:
REPRODUCTIVE TOXICITY:
TERATOGENICITY:
MUTAGENICITY:
TOXIC SYNERGISTIC PRODUCTS:
T.L.V.\T.W.A. 50 ppm. (25 ppm for operating rooms: OSHA)
NONE
NONE
NOT AVAILABLE
TCLo 20%/8hrs/day 28 days male rat.
TCLo 5,000 ppm 6 hours inhl-rat (1 – 19 pregn.)
Chromosome loss in Drosophila after 6 mins @ 99%.
NONE
UYI 109-3
FIRST AID
EYE:
INGESTION:
INHALATION:
SKIN:
Escaping Gas may harm the unprotected eye if delivered at pressures higher than
atmospheric. Obtain medical attention if damages are suspected or present.
Not applicable
Move victim to fresh air if possible. Obtain medical attention. If breathing has stopped ,
administer C.P.R. If breathing is difficult give oxygen.
Contact with cold liquid or vapours may cause frostbite. Treat frostbite if present. Obtain
medical attention.
PREVENTIVE MEASURES
PERSONAL PROTECTION
EYE:
HAND:
FEET:
CLOTHING:
RESPIRATOR:
Safety glasses or goggles to protect from accidental deliveries (leaks) under pressure.
Not applicable.
Safety footwear where applicable.
Long sleeves, trousers recommended.
Not applicable
ENGINEERING CONTROLS: Provide ventilation. Keep oil, grease, and combustible materials away.
SPILL AND LEAK PROCEDURE:
Remove all source of ignition. Clear the area. Spills on combustible surfaces may cause a fire hazard. Try to stop the
leak at source if without risk. Gas will dissipate depending on the site/area ventilation. Verify oxygen concentration prior
to re-entry.
WASTE DISPOSAL:
No wastes may be generated other than empty containers.
HANDLING PROCEDURES & EQUIPMENT:
Use in ventilated areas. Keep away from Oil, Grease, Combustible, Flammable materials.
Use appropriate carts for moving containers. Secure container when in use. Close the container valve when NOT in
use, or when empty. Secure (restrain) during transporation or use.
STORAGE REQUIREMENTS:
Store in well ventilated areas. Keep away from sources of ignition. Store at temperatures below 52 oC.
SPECIAL SHIPPING INFORMATION:
Transport upright in well-ventilated vehicle. Do not transport in trunk of enclosed vehicle. Commercial (cylinders)
quantities may NOT be transported in passenger compartments.
T.D.G. SHIPPING NAME:
T.D.G. P.I.N. / U.N. :
Nitrous Oxide
1070
PREPARED BY:
TEL:
EFFECTIVE DATE:
JOSEF GAS
(416) 658-1212
AUGUST 2014
T.D.G. CLASSIFICATION CLASS(ES):
2.2 (5.1)