HOWARD REALUBIT 3824 Fourth Ave #1 San Diego, CA 92103 Cell Phone (619) 333-0032 howie@chemshark.com OBJECTIVE Research position with publication authorship in patients diagnosed with TBI undergoing ECT (UCSD Independent Medical Research – 199). QUALIFICATIONS Clinical research experience at Veteran’s Hospital Cardiology Unit and Oncology research experience in Santa Monica at an established private practice. SOCRA Member. Six years of medical experience in the military. Proficient in interacting with voluminous & culturally diverse organization. Thorough knowledge of emergency and ward care. Extensive inpatient and outpatient experience. Routine Laboratory experience. Curently pursuing Bachelor of Science degree in Biochemistry/Chemistry at UCSD Muir College. Currently completing Drug Discovery Certification at UCSD Extension. EDUCATION Currently Pursuing Bachelor’s Degree in UCSD Biochemistry (Chemistry Dept). Currently Pursuing Certification in Drug Discovery, UCSD Extension Research Coordinator Training Program at Johns Hopkins University, 2007 Santa Monica College, 2008-2010 California Vocational Nursing Licensure (Self-taught—challenged board), 2004 Hospital Corpsman “A” School Graduate, 1999 Field Medical Service School, Camp Pendleton, 1999 2 EMPLOYMENT May 11 – Licensed Vocational Nurse, Veteran's Admin. Hospital, La Jolla Present Inpatient Psychiatric Facility, 2-south. BCMA Committee: audit RNs and LVNs from other departments to ensure compliance with bar-code-medication-administration procedures, attend monthly meeting with hospital service chiefs. Jan 10 -- Chemistry Student, UC San Diego Full time to ¾ time course schedule (12-16 units) per quarter. Majoring in Biochemistry at Chemistry Department. Courses completed include, but not limited to: Fundamentals of ANALYTICAL CHEM, with emphasis on quantitative chemical analysis techniques including separation and gravimetric methods. PROTEIN CHEMISTRY, application of techniques to study protein structure and function, including electrophoresis protein purification, column chromatography, enzyme kinetics and immunochemistry. BIOCHEM STRUCTURE & FUNCTION, introduction to biochemistry, BIOCHEM ENERGETICS & METABOLISM, metabolic reactions in the cell which catalyzes energy production. BIOSYNTHESIS of MACRO MOLECULES, mechanisms of biosynthesis of macro molecules—particularly proteins and nucleic acids. CHEMISTRY of ENZYME CATALYZED REACTIONS, discussion of representative enzymes, mechanisms, and relation to enzyme structure. INORGANIC CHEM, structure, bonding, and reactivity with emphasis on tran- Howard Realubit 3 sition metals and other elements using filled d-orbitals to form bonds. Coordination chemistry in terms of valence, crystal field, and molecular orbital theory. CALCULUS for SCIENTISTS & ENGINEERS (2-series), including Differential and Vector. PHYSICS and O-CHEM courses taken at Santa Monica College. Apr 08 -- Visiting Nurse, Angeles Home Health Care Jan 10 Administered care per MD orders including, but not limited to, drawing blood for CBC/CMP, and PT/INR using portable machine and delivering specimens. Filing requisition forms to the laboratory. Performing wound care to the instructions of doctor's order (wet-to-dry, dry-to-dry, debridement, packing, documentation). Administering medications via oral, and intramuscular, subcutaneous, intravenous injections. Reporting PT/PTT/INR coagulation test results obtained via Hemosense machine to MD office. Patient teaching of etiology of specific diseases, as well as expected disease processes. Patient teaching of medications ranging from diuretics, calcium channel blockers, to homeopathic remedies. Mixing and administration of experimental and research medications i.e., Fuzeon for HIV. Apr 07 Apr 08 Clinical Research Coordinator, The Angeles Clinic & Research Institute Experienced research coordinator and scheduler for a mid-sized private practice with large celebrity clientele base for Melanoma specialists. Juggled 5 actively enrolling protocols and maintained 4 protocols closed to enrollment. Ensured Case Report Forms, data Howard Realubit 4 query documents were all complete prior to each monitor’s visit and inspection. Interacted continuously with patients and gave informed consent regarding the studies and the experimental drugs. Ensured 100% accuracy in verifying doctor’s order and supervised chemo nurses’s administration of drugs by providing advice on what concomitant drugs were available for emergencies/adverse events, as well as appropriate dosage based on BMI or cohort assigned. Collected and processed lab data (spun, eluted, and, drew blood from lines flushed with heparin). Vitals, 12-lead ECG, vaccinations. Multiple Phase I/II studies. Served as liaison to PI and sponsor(s), by constantly updating sponsor on Phase I, dose escalation studies with instant scans and labs upon receipt. Provided PI with custom updates on all subjects to prepare him/her for teleconferences & presentations. Scheduled 12 active patients (qweekly visits) on 5 active studies for over seven months. Traveled to separate facility qweekly to manage patient as both coordinator & research nurse. Worked with 6 separate oncologists on different studies (prostate, melanoma, gastric). Successfully managed and closed 5 inherited studies with few to no deviations to protocol, despite minimal training. Trials included, but not limited to the following: CURAGEN (Phase II) for treating metastatic melanoma with brain mets using novel chemo attached to monoclonal antibody designed to target tumor receptors. DARA (Phase II) for neuropathic pain secondary to cancer. Study of MDX-010 in Patients With Metastatic Hormone-Refractory Howard Realubit 5 Prostate Cancer (MDX010-21). ATTENUON: Randomized Trial of ATN-224 and Temozolomide in Advanced Melanoma, as an Antiangiogenesis drug for multiple metastasis. Aug '06 Mar '07 Nocturnal Nursing Supervisor & Admissions, Passages Rehabilitation Facility in Malibu {Weekend & Holiday Shifts} Managed multiple patients in drug rehabilitation setting; Accepted new & incoming patients at all hours of the night, ensuring proper admit documentation and on-duty physican remote reporting; Monitored celebrity and high-profile patients' health through detoxification stages and drug-screening phases; Supervised medical technicians on-duty. Obtained patient history, monitored vital signs, administered medication per physician orders and dealth with emergency medical protocol when necessary. Aug 06 Apr 07 Clinical Research Coordinator, VA Hospital Brentwood Cardiology Managed multiple cardiological studies in Emergency department, Cath Lab, CCU, and Telemetry. Tasked to complete overall study execution from Site Initiation Visits, Investigator Meetings, IRB paperwork submission, Research & Development committee and research pharmacy negotiations, data encryption & security, drug accountability and dispensing, weekend follow-ups, patient recruitment, working with subjects who have congestive heart failure, severe high blood pressure, kidney failure, acute coronary syndromes, Howard Realubit 6 Site close-downs, archiving past data, study progress reporting via HTML 2.0, thoroughly participating in monitor visits, completed two successful sponsor-audits (warranted due to volume of enrolled subjects). Created SOPs and successfully trained newer coordinators to cover each trial (in case of absence). Trials include, but not limited to, VELOCITY (Phase III), a calcium-channel blocker aimed at treating those with severe hypertension (systolic>180, diastolic>100) and controlling within a 10 hour period, administered intravenously. ZEALAND (Phase II), an aquaporetic—altered version of diaphoretic—to treat those with NYHA Class II-III congestive heart failure and/or LVEF<20%. SHINE (Phase III-IV) study for testing a novel drug that has shorter half-life than Plavix. Oct 05 - Home Health Care Nurse (shift & visits), Universal Home Health Present Provided care to patient in Persistent Vegitative State. Gave feedings through gastrointestinal tube. Ensured adequate breathing via ventilator and provided tracheal tube care & maintenance. Dispensed medications according to doctor’s orders. Coached pt. during breathing, and ROM exercises. Kept accurate nursing and progress notes to submit to headquarters. Feb 04 Oct 05 Licensed Vocational Nurse, UCLA Family Medicine Prepped patients for the doctor by taking vitals, med hx, Howard Realubit 7 giving immunizations (peds, adults), ordering meds from insurance companies, dealing with managed care, billing issues, obtaining lab samples, diagnostic results, preparing med chart, scheduling patients, prepping procedure room for intrauterine device insertion/removal, nitro for dermatological lesions, colposcopies, pap smears, endometrial biopsies, FNA, punch biopsies and referral to specialists. Jan 99 - Hospital Corpsman, 2nd Class, U.S. Navy & Marine Corps Oct 04 Ensured safety and welfare of over 1,200 Marines and Eight Sailors. Served as a mediator and liaison between layman Marines & professional physicians. Assisted with Physical Exam & makes basic Medical Assessments; Recognize abnormal signs & symptoms; Administers IV and collects specimens; Obtain Vital Signs; Give Oral, IM, Subcutaneous, Intradermal medications; Admits transfers; Discharges patients; Awarded Navy Achievement Medal as Junior Sailor of the Year 2001, for Division, 11th Marine Expeditionary Unit, West Coast USA. REFERENCES Military Vidal Leon – US Navy (562) 505-6783 {Personal} Chief Georgina Austin – Retired Navy Chief (760) 497-6652 {Professional} Hugh Regidor — Camp Pendleton School of Infantry (760) 214-0104 {Personal} Nursing Howard Realubit 8 Shirley Uy, MD – Associate Professor at UCLA (310) 794-9956 {Professional} Research Brenda Fulham – Research Mgr, Premiere Oncology (prev. The Angeles Clinic) (818) 271-8991 Blanca Ledezma, NP – Nurse Practitioner (The Angeles Clinic) (310) 947-1888 Linda Nahorniak – Monitor/Study Consultant (775) 742-3668 Diep Severson – Research Pharmacist (310) 487-1235 Sharon Campbell – Brentwood Research Admin. (310) 312-1554 x211 Personal Dr. Larry Friedman – UCSD Telemedicine, OWEN Clinic, UCSD SOM Professor (619) 840-8399 Howard Realubit