BIRAX Regenerative Medicine Conference

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FINAL SCIENTIFIC PROGRAMME
Tuesday, 22 November 2011
09:00
Registration and Coffee
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10:00 - 10:30
Opening Session
Senate Hall
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Chairperson:
Adee Matan, Israel
WELCOME
Rivka Carmi, President, Ben-Gurion University of the Negev
Matthew Gould, British Ambassador to Israel
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10:30 - 13:00
Plenary Session
Senate Hall
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HIGHLIGHTS OF REGENERATIVE MEDICINE
Chairpersons:
Lord Naren Patel, UK
Benjamin Geiger, Israel
10:30
HUMAN EMBRYONIC STEM CELLS – FROM BENCH TO BEDSIDE
Benjamin E. Reubinoff, Hadassah University Medical Center,
Jerusalem, Israel
11:00
V BIO-INSPIRED MATERIALS FOR REGENERATIVE MEDICINE
Smadar Cohen, Ben-Gurion University of the Negev, Beer Sheva,
Israel
11:30
Coffee Break
12:00
TISSUE ENGINEERING: AN ENABLING TECHNOLOGY
Dame Julia Polak, Imperial College London, UK
Tuesday, 22 November 2011 (cont.)
12:30
EPICARDIUM-DERIVED CARDIAC REPAIR
Paul R. Riley, University College London, UK
13:00
Lunch
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14:00 - 18:00
Session 2A
Barkan Hall
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TRANSLATIONAL CELL THERAPY IMMUNOLOGY & MANUFACTURE
Chairpersons:
Tamir Ben-Hur, Israel
Julie Daniels, UK
14:00
STEM CELL THERAPIES FOR SKELETAL DISORDERS
Dan Gazit, The Hebrew University of Jerusalem, Israel
14:30
HUMAN PLURIPOTENT STEM CELLS: IMPLICATIONS FOR BASIC
AND TRANSLATIONAL CARDIAC RESEARCH
Lior Gepstein, Technion, Israel Institute of Technology, Haifa, Israel
15:00
STEM CELL THERAPY IN ALS
Daniel Offen, Tel Aviv University, Tel Aviv, Israel
15:30
STEM CELL THERAPY FOR BLINDING CORNEAL DISEASE
Julie Daniels, UCL Institute of Ophthalmology, London, UK
16:00
Coffee Break
16:30
THE CHONDROCYTE: A FLEXIBLE TOOL FOR RECONSTRUCTION
James B. Richardson, RJAH, NHS Trust, UK
17:00
TISSUE ENGINEERING CHALLENGES IN ORTHOPAEDIC SURGERY
Andrew McCaskie, Newcastle University, UK
17:30
Poster presentations
18:00
Buses return to hotel
19:00
Depart for Bedouin Style Dinner - one bus from the university and two buses from
the hotel
Tuesday, 22 November 2011 (cont.)
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14:00 - 18:00
Session 2B
Oren Hall
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STEM CELL / TRANSPLANTATION IMMUNOLOGY & MANUFACTURE
Chairpersons:
Paul Fairchild, UK
Yair Reisner, Israel
14:00
MECHANISMS OF PANCREATIC BETA CELL REGENERATION
Yuval Dor, The Hebrew University of Jerusalem, Israel
14:30
ALPHA-1 ANTITRYPSIN PROTECTS CELL TRANSPLANTS,
FACILITATES ANGIOGENESIS AND ENHANCES GRAFT-SPECIFIC
IMMUNE TOLERANCE IN VIVO
Eli Lewis, Ben-Gurion University of the Negev, Beer Sheva, Israel
15:00
PIG EMBRYONIC PANCREATIC TISSUE FOR CORRECTION OF
DIABETES
Yair Reisner, Weizmann Institute of Science, Rehovot, Israel
15:30
DENDRITIC CELLS AND PLURIPOTENCY: UNEXPECTED
ALLIES IN THE PURSUIT OF IMMUNOTHERAPY
Paul Fairchild, University of Oxford, Oxford, UK
16:00
Coffee Break
16:30
MANUFACTURE AND SUPPLY OF A CELLULARISED BIOCOMPATIBLE
POLYMER SCAFFOLD AS AN ADVANCED THERAPY MEDICINAL PRODUCT
FOR TRACHAEAL REPLACEMENT
Mark Lowdell, University College London, UK
17:00
CELL THERAPY TO PROMOTE TRANSPLANTATION TOLERANCE: A WINNING
STRATEGY?
Giovana Lombardi, King’s College London, London, UK
17:30
Poster presentations
18:00
Buses return to hotel
19:00
Depart for Bedouin Style Dinner - one bus from the university and two buses from
the hotel
Wednesday, 23 November 2011
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08:15 - 09:00
Optional Session A
Barkan Hall
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QUESTIONS AND ANSWERS
Questions and answers related to the BIRAX Regenerative Medicine
Initiative Call for Proposals, British Council, Israel
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08:15 - 09:00
Optional Session B
Oren Hall
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PARTY PITCH YOUR POST-DOC
Science Communication / Networking for early career researchers
Facilitated by Aarathi Prasad, freelance science journalist, author and broadcaster,
Natural Resources / Science Communication Advisor, British Council, UK
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09:00 - 12:30
Session 3A
Barkan Hall
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STEM CELL DERIVATION, GENOMICS, GENOMICS REPROGRAMMING &
EPIGENETICS
Chairpersons:
Nissim Benvenisty, Israel
Paul De Sousa, UK
09:00
THE ROLE OF PLURIPOTENT STEM CELLS IN MODELING HUMAN DISORDERS
Nissim Benvenisty, The Hebrew University of Jerusalem, Israel
09:30
UNDERSTANDING THE IDENTITY AND STABILITY OF
PLURIPOTENT CELL STATES
Jacob Hanna, Weizmann Institute of Science, Rehovot, Israel
10:00
THE ROLE MIRNAA PLAY AS DEVELOPMENTAL SWITCHES
Eran Hornstein, Weizmann Institute of Science, Rehovot, Israel
10:30
DEVELOPING SCALABLE AUTOMATION OF HUMAN PLURIPOTENT STEM
CELL (HPSC) EXPANSION AND DIFFERENTIATION FOR MULTIPLE
SCREENING APPLICATIONS
Lorraine Young, University of Nottingham, UK
11:00
Coffee Break
11:30
PLURIOPTENT STEM CELL TRANSLATION: BASIC AND APPLIED
SCIENCE SUPPORTING HUMAN EMBRYONIC STEM CELLS IN
REGENERATIVE MEDICINE
Paul De Sousa, University of Edinburgh, UK
12:00
MESODERM DIFFERENTIATION IN PLURIPOTENT MAMMALIAN
STEM CELLS
Roger Pedersen, University of Cambridge, UK
12:30
Lunch
Wednesday, 23 November 2011 (cont.)
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09:00 - 12:30
Session 3B
Oren Hall
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BIOMATERIALS, TISSUE ENGINEERING
Chairpersons:
Hanna Rapaport, Israel
Kevin Shakesheff, UK
09:00
NANOTECHNOLOGICAL STRATEGIES FOR MENDING BROKEN HEARTS
Tal Dvir, Tel Aviv University, Israel
09:30
NATURAL EXTRACELLULAR MATRIX PLATFORMS TOWARDS ENGINEERING
OF THICK CARDIAC CONSTRUCTS
Marcelle Machluf, Technion, Israel Institute of Technology, Haifa, Israel
10:00
SELF ASSEMBLED ACIDIC PEPTIDES; FROM DESIGN TO
BIOMATERIALS FOR BONE TISSUE REGENERATION
Hanna Rapaport, Ben-Gurion University of the Negev, Beer Sheva, Israel
10:30
NEW MATERIALS-BASED STRATEGIES FOR REGENERATIVE MEDICINE
Molly Stevens, Imperial College London, UK
11:00
Coffee Break
11:30
CONTROLLING CELL BEHAVIOUR USING 3D ARCHITECTURES
Kevin Shakesheff, University of Nottingham, UK
12:00
CONTROLLING CELLS FOR USE IN CLINICAL THERAPIES USING MAGNETIC
NANOPARTICLES
Alicia El Haj, Keele University, UK
12:30
Lunch
Wednesday, 23 November 2011 (cont.)
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13:30 - 16:30
Session 4A
Barkan Hall
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STEM CELL BIOLOGY: LESSONS FROM DEVELOPMENT
Chairpersons:
Sue Kimber, UK
Dov Zipori, Israel
13:30
A REGULATORY NETWORK OF TISSUE-SPECIFIC MODIFIERS UNDERLIES
THE ETIOLOGY OF DIGEORGE DELETION SYNDROME
Eldad Tzahor, Weizmann Institute of Science, Rehovot, Israel
14:00
TRANSLATING HUMAN KIDNEY DEVELOPMENT TO CELL
THERAPY OF RENAL INJURY AND TARGETED THERAPY OF
RENAL CANCER
Benjamin Dekel, Sheba Medical Center, Tel Hashomer, Israel
14:30
MESENCHYMAL STROMAL CELLS AS A PARADIGM OF THE STEM STATE:
PLASTIC NATURE ENTAILING HETEROGENEITY AND CAPACITY TO DEDIFFERENTIATE
Dov Zipori, Weizmann Institute of Science, Rehovot, Israel
15:00
REGULATION OF NEURAL STEM CELLS BY INTEGRINS AND
EXTRACELLULAR MATRIX
Charles ffrench-Constant, University of Edinburgh, UK
15:30
TWINNING: THE ULTIMATE REGENERATION
Claudio D. Stern, University College London, UK
16:00
GENERATION OF CHONDROGENIC CELLS FROM HUMAN PLURIPOTENT
CELLS
Sue Kimber, University of Manchester, UK
16:30
Coffee Break
Wednesday, 23 November 2011 (cont.)
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13:30 - 16:30
Session 4B
Oren Hall
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GENE THERAPY AND GENE-MODIFIED CELLS
Chairpersons:
Andrew Baker, UK
Tamir Ben-Hur, Israel
13:30
DEVELOPMENT OF BETA-CELL REPLACEMENT THERAPY FOR DIABETES
Shimon Efrat, Tel Aviv University, Israel
14:00
USE OF AUTOLOGOUS VENOUS ENDOTHEIAL AND SMOOTH MUSCLE CELLS
MODIFIED BY GENE TRANSFER FOR INDUCTION OF ARTERIOGENESIS
Moshe Flugelman, Technion, Israel Institute of Technology, Haifa, Israel
14:30
DIRECT REPROGRAMMING OF HUMAN ADULT CELLS INTO
INSULIN PRODUCING CELLS; CELL REPLACEMENT THERAPY FOR DIABETIC
PATIENTS
Sarah Ferber, Sheba Medical Center, Tel Hashomer, Israel
15:00
GENE THERAPY FOR IMMUNODEFICIENCY
Adrian Thrasher, University College London, UK
15:30
MODIFYING VEIN GRAFTS BY GENE THERAPY
Andrew Baker, University of Glasgow, UK
16:00
CELL THERAPY FOR MULTIPLE SCLEROSIS
Tamir Ben-Hur, Hadassah Medical Center, Jerusalem, Israel
16:30
Coffee Break
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17:00 - 19:00
Closing Plenary Discussion
Senate Hall
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POSTER AWARDS
Prizes will be awarded for the 3 best posters by Simon Kay, Director, British Council
Israel and Adee Matan, Science and Innovation Attache, British Embassy
REGENERATIVE MEDICINE: THE ROAD AHEAD
Moderators:
Chris Mason, UK
Smadar Cohen, Israel
Panelists:
Martin Birchall, UK
Anthony Hollander, UK
Joseph Itskovitz-Eldor, Israel
Michel Revel, Israel
Yosef Shiloh, Israel
Glyn Stacey, UK
CLOSING REMARKS
Simon Kay, Director, British Council Israel
19:30
Return transfer to the hotel
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