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VITA
Eleanor Rose Deardorff was born in Santa Fe, New Mexico on January 20th, 1978 to
David Deardorff and Anna Richards. She graduated from Santa Fe High School in 1996.
While completing her graduate work at the University of Texas Medical Branch Eleanor
served as a graduate student senator in the student government association. She also
received the James W. McLaughlin Predoctoral Fellowship, the National Institute of
Health T32 Training Grant in Biodefense and the Center for Disease Control’s
Fellowship Training Grant in Vector Borne Infectious Diseases. Eleanor won 3rd place in
the 2008 Hector P. Garcia cultural competence essay contest for her essay “Home away
from home” on her experiences as an American student doing field work in rural areas of
coastal Chiapas, Mexico.
Education
B.A. May 2001, Reed College, Portland, Oregon.
Publications
Greene, I. P., Wang, E., Deardorff, E. R., Milleron, R., Domingo, E., and Weaver, S. C.
Effect of alternating passage on adaptation of Sindbis virus to vertebrate and invertebrate
cells. 2005. J. Virol., Vol 79, No. 22, p.14253—14260.
Deardorff, E.R., Estrada-Franco, J.G., Brault, A.C., Navarro-Lopez, CampomanesCortes, A., Paz-Ramirez, P., Solis-Hernandez M., Ramey, W., R., Davis, C.T., Beasley,
D.W.C., Tesh, R.B., Barrett, A.D.T., and Weaver, S.C. Introductions of West Nile Virus
to Mexico. 2006. Emerging Infectious Disease, Vol.12, No.2, p.314—318
Forrester, N. L., Kenney, J. L., Deardorff, E. R., Wang, E. & Weaver, S.C. Western
equine encephalitis submergence: lack of evidence for a decline in virus virulence. 2008.
Virology, Vol. 380, No. 2, p. 170-172.
Deardorff, E.R., Forrester, N.L., Travasos da Rosa, A., Estrada-Franco, J.G., NavarroLopez, R., Tesh, R.B., Weaver, S.C. Experimental infections of potential Mexican
reservoir hosts with Venezuelan equine encephalitis virus. 2009. Emerging Infectious
Disease, Vol. 15, No. 4, p.519—525.
Deardorff, E.R., Forrester, N.L., Travasos da Rosa, A., Estrada-Franco, J.G., NavarroLopez, R., Tesh, R.B., Weaver, S.C. Experimental Infections of Oryzomys couesi With
Sympatric Arboviruses from Mexico. 2009, American Journal of Tropical Medicine and
Hygiene, in Press.
Summary of Dissertation
I investigated the emergence of Venezuelan equine encephalitis virus in Chiapas Mexico.
This virus was not previously associated with equine disease in Mexico. The evolution of
the equine virulent phenotype was thought to have resulted in a mosquito vector switch
from Culex (Melanoconion) taeniopus to Aedes (Ochlerotatus) taeniorhynchus as a result
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of land-use changes. I spent a year capturing wild rodents and mosquitoes and found little
evidence of virus circulation. I then imported rodents from five species into the lab for
experimental evaluation as virus amplifying hosts and found that VEEV may use a
variety of rodents as amplifying hosts in this area. Lastly I encountered unexpectedly
high numbers of Culex (Mel.) taeniopus and decided to colonize this mosquito in order to
experimentally evaluate it’s ability to transmit equine virulent VEEV. I found that equine
virulent virus infects and is transmitted by this mosquito with high efficiency and is likely
maintained in transmission foci by Culex (Mel) taeniopus during inter-epizootic periods.
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