CSU "Analytical spectrometry" Ltd. Development new methods of diagnosis and treatment of various diseases of endocrine, cardiovascular and urogenital systems and their application Contact person details Name: KARTSOVA , Liudmila ( Professor) Position: Project group leader Name of Organisation: CSU "Analytical spectrometry" Ltd. URL: E-mail: Contact Telephone: +7-81242-84044 Fax number: +7-81254-54396 Collaboration Type: Project Proposal Title: Development new methods of diagnosis and treatment of various diseases of endocrine, cardiovascular and urogenital systems and their application Participation: Type A Type Details: The aim of the project is developing methods of rapid and highly efficient diagnosis of various diseases based on determination and monitoring important biomarkers and drugs in biological objects (urine, plasma and blood serum, tissue of bladder and brain structures) by chromatography and electrophoresis. Our specific fields of expertise are: - Development a sample preparation procedure of biological liquids (urine, plasma, blood serum, tears, saliva) for determination of biological active substances by HPLC-MS, CE-DAD, CE-MS. - Development and applying specific methods off-line and on-line concentration of analytes for reducing their LOD. - Determination of antitumoral drugs (mitomicin C, gemcitabine, doxorubicine, cisplatinum, oxibutinin, marcaine, paclitaxel and other) in bladder tissue. - Investigation of residual drug (steroidal and nonsteroidal nature) in urine and serum of blood. - Simultaneously determination of catecholamines (adrenaline, noradrenaline, dopamin) and their metabolites in urine and plasma of blood for diagnosis nervous, cardiovascular and cancer disease. - Carrying out the reference research of microalbuminuria diagnosis. - Clinical research and treatment of urolithiasis accompany with Med. Univ. - Investigation the new method of intravesical electromotive drug administration for superficial bladder cancer therapy. Our laboratory equipped: -HPLC-UV, ED, FLD and ESI-MS detections; -HPTLC-UV; -CE-DAD and ESI-MS detections; -MALDI-TOF MS. Programme: FP7 , FP7-COOPERATION , FP7-HEALTH Instruments: CP-FP Small or medium-scale focused research project Research interest: Expiry Date: 2009-02-12 Workprogramme area(s)/key action(s): (FP7-HEALTH HEALTH-2007-2.4.2) Cardiovascular disease (FP7-HEALTH HEALTH-2007-1.2) Detection, diagnosis and monitoring (FP7-HEALTH HEALTH-2007-2.4.1) Cancer Target Partner Expertise: = The aim of this proposal is collaboration with teams with similar object of investigation for comparing and adding of physicochemical and clinical results. = Partners experienced in using minimum invasive and noninvasive ways of drug delivery. = Carrying out a reference research of different therapy of superficial bladder cancer: common therapy (passive diffusion, BCG) and intravesical electrophoresis. Country: Any country Organization Details Name: CSU "Analytical spectrometry" Ltd. Department: Address: St.Petersburg Russian Federation Type: Research, SME (Small or Medium sized Enterprise) Number of Employees: 10 - 49 Details: SIC Codes: Life Sciences , Medical biotechnology , Measurement Methods , Medicine, Health , Scientific Research Keywords: biomarker bladder cancer drug administration and monitoring electrophoresis HPLC-MS Partners already acquired: