Takano-Maruyama, M., Hase, K., Fukamachi, H., Kato, Y., Koseki, H., *Ohno, H.: Foxl1-deficient
mice exhibit aberrant epithelial cell positioning due to dysregulated EphB/EphrinB in the small
intestine. Am. J. Physiol. Gastrointest. Liver Physiol. 291: G163-G170, 2006
Hase, K., Murakami, T., Takatsu, H., Shimaoka, T., Iimura, M., Hamura, K., Kawano, K., Ohshima,
S., Chihara, R., Itoh, K,, Yonehara, S.,*Ohno, H.: The membrane-bound chemokine CXCL16
expressed on follicle-associated epithelium and M cells mediates lympho-epithelial interaction in
GALT. J. Immunol., 176 (1): 43-51, 2006.
Mitsunari, T. Nakatsu, F., Shioda, N., Love, P.E., Grinberg, A., Bonifacino, J.S., *Ohno, H.: Clathrin
adaptor AP-2 is essential for early embryonal development. Mol. Cell. Biol. 25 (21): 9318-9323,
2005.
Voigt, B., Timmers, A., Samaj, J., Hlavacka, A., Ueda, T., Preuss, M., Nielsen, E., Mathur, J., Emans,
N., Stenmark, H., Nakano, A., Baluska, F., *Menzel, D.: Actin-based motility of endosomes is linked
to the polat tip growth of root hairs. Eur. J. Cell Biol. 84:609-621, 2005.
Kitazawa, D., Hatakeda, Y., Kamada, M., Fujii, N., Miyazawa, Y., Hoshino, A., Iida, S., Fukaki, H.,
Morita, M. T., Tasaka, M., Suge, H., *Takahashi, H.: Shoot circumnutation and winding movements
require gravisensing cells. Proc. Natl. Acad. Sci. U. S. A. 102:18742-18747. 2005.
*Sato, K., Nakano, A.: Reconstitution of cargo-dependent COPII coat assembly on proteoliposomes.
Methods Enzymol. 404:83-94, 2005.
Nishimura, Y., Yoshinari, T., Naruse, K., Yamada, T., Sumi, K., Mitani, H., Higashiyama, T.,
*Kuroiwa, T.: Active digestion of sperm mitochondrial DNA in single living sperm revealed by
optical tweezers. Proc. Natl. Acad. Sci. U. S. A. 103:1382-1387, 2006.
Mori, T., Kuroiwa, H., Higashiyama, T., *Kuroiwa, T.: GENERATIVE CELL SPECIFIC 1 is
essential for angiosperm fertilization. Nat. Cell Biol. 8:64-71, 2006.
Satoh, T., Sato, K., Kanoh, A., Yamashita, K., Kato, R., Nakano, A., *Wakatsuki, S.: Structures of
carbohydrate recognition domain of Ca2+-independent cargo receptors Emp46p and Emp47p. J.
Biol. Chem. 281:10410-10419, 2006.
Matsuura-Tokita, K., Takeuchi, M., Ichihara, A., Mikuriya, K., *Nakano, A.: Live imaging of yeast
Golgi cisternal maturation.
Nature DOI: 10.1038/nature04737, 2006.
Yahara, N., Sato, K., *Nakano, A.: An Arf1p GTPase-activating protein, Glo3p, executes its
regulatory function through the Glo3 motif at its C-terminus. J. Cell Sci. 119:2604-2612, 2006.
Nakanishi-Matsui, M., Kashiwagi, S., Hosokawa, H., Cipriano, D.J., Dunn, S.D., Wada Y., *Futai,
M.: Stochastic high-speed rotation of Escherichia coli ATP synthase F1 sector: the
subunit-sensitive rotation. J. Biol. Chem. 281: 4126-4131, 2006.
Abe, T., Matsumura, S., Katano, T., Mabuchi, T., Takagi, K., Xu, L., Yamamoto, A., Hattori, K, Yagi,
T., Watanabe, M., Nakazawa, T, Yamamoto, T., Mishina, M., Nakai, Y., Ito, S. Fyn kinase-mediated
phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of
neuropathic pain. Eur. J. Neurosci. 22: 1445-1454, 2005.
Kano, F., Kondo, H., Yamamoto, A., Kaneko, Y., Uchiyama, K., Hosokawa, N., Nagata, K., Murata,
M. NSF/SNAPs and p97/p47/VCIP135 are sequentially required for cell cycle-dependent
reformation of the ER network. Genes Cells 10: 989-999, 2005.
Matsui, M., Yamamoto, A., Kuma, A., Ohsumi, Y., Mizushima N. Organelle degradation during the
lens. and erythroid differentiation is independent of autophagy. Biochem Biophys Res Commun.
339: 485-489, 2005.
Uehara, S., Jung, S.K., Morimoto, R., Arioka, S., Miyaji, T., Juge, N., Hiasa, M., Shimizu, K.,
Ishimura, A., Otsuk,a M., Yamamoto, A., Maechler, P., Moriyama, Y. Vesicular storage and secretion
of L-glutamate from glucagon-like peptide 1-secreting clonal intestinal L cells. J Neurochem. 96:
550-560, 2006.
Nakanishi, K., Ida, M., Suzuki, H., Kitano, C., Yamamoto, A., Mori, N., Araki, M., Taketani, S.
Molecular characterization of a transport vesicle protein Neurensin-2, a homologue of Neurensin-1,
expressed in neural cells. Brain Res. in press, 2006
Ishida Y., Kubota, H., Yamamoto, A., Kitamura, H., Bahinger, H. P., Nagata, K. Type I collagen in
Hsp47-null cells is aggregated in ER and deficient in N-propeptide processing and fibrillogenesis.
Mol. Biol. Cell in press , 2006
Hara, T., Nakamura, K., Matsui, M., Yamamoto, A., Nakahara, Y., Suzuki-Migishima, R., Yokoyama,
M., Mishima, K., Saito, I., Okano, H., Mizushima, N. Suppression of basal autophagy in neural cells
causes neurodegenerative disease in mice, Nature in press , 2006
Takahashi, K., Kimura, Y., Nagata, K., Yamamoto, A., Matsuo, M., Ueda, K. ABC proteins, key
molecules for lipid homeostasis, Med. Mol. Morphol. 38: 2-12, 2005.
Fukuda, M., Yamamoto, A. Assay of the Rab binding specificity of Rabphilin and Noc2:target
molecules for Rab27. In Vesicular Trafficking GTPases, Methods in Enzymol. 403: 403-481, 2006.
Uchiyama, T., *Kumaki, S., Ishikawa, Y., Onodera, M., Sato, M., Du, W., Sasahara, Y., Tanaka, N.,
Sugamura, K., and Tsuchiya, S. Application of HSVtk suicide gene to X-SCID gene therapy:
ganciclovir treatment offsets gene corrected X-SCID B cells. Biochem. Biophys. Res. Commun.
341: 391-398, 2006
Ishikawa, Y., *Tanaka, N., Murakami, K., Uchiyama, T., Kumaki, S., Tsuchiya, S.,
Kugoh, H., Oshimura, M., Calos, M. P., and Sugamura, K. Phage phiC31 integrase-mediated
genomic integration of the common cytokine receptor gamma chain in human T-cell lines. J. Gene.
Med. 2006 (in press)
Shim, J. H., Xiao, C., Paschal, A. E., Bailey, S. T., Rao, P., Hayden, M. S., Lee, K. Y., Bussey, C.,
Steckel, M., Tanaka, N., Yamada, G., Akira, S., Matsumoto, K., and *Ghosh, S. TAK1, but not TAB1
or TAB2, plays an essential role in multiple signaling pathways in vivo. Genes. Dev. 19:
2668-2681.2005
Niinuma, A., Higuchi, M., Takahashi, M., Oie, M., Tanaka, Y., Gejyo, F., Tanaka, N.., , Xie, L.,
Green, P. L., and *Fujii, M. Aberrant activation of the interleukin-2 autocrine loop through the
nuclear factor of activated T cells by nonleukemogenic human T-cell leukemia virus type 2 but not
by leukemogenic type 1 virus. J. Virol. 79: 11925-11934. 2005
Hamada, K., Sasaki, T., Koni, P., Natsui, M., Kishimoto, H., Sasaki, J., Yajima, N., Horie, Y.,
Hasegawa, G., Naito, M., Miyazaki, J., Suda, T., Itoh, H., Nakao, K., Mak, T., Nakano, T. & *Suzuki,
A.: The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis.
Genes&Dev. 19, 2054-2065, 2005
*Nakano, K., Mabuchi, I.: Actin-depolymerizing protein Adf1 is required for formation and
maintenance of the contractile ring during cytokinesis in fission yeast. Mol. Biol. Cell : in press,
2006.
*Nakano, K., Bunai, F., Numata, O.: Stg1 is a novel SM22/transgelin-like actin-modulating protein
in fission yeast. FEBS Lett. 579: 6311-6316, 2005.
Mutoh, T., Nakano, K., *Mabuchi, I.: Rho1-GEFs Rgf1 and Rgf2 are involved in formation of cell
wall and septum, while Rgf3 is involved in cytokinesis. Genes Cells 10: 1189-1202, 2005.
*Nakano, K., Arai, R., Mabuchi, I.: Small GTPase Rho5 is a functional homologue of Rho1, which
controls cell shape and septation in fission yeast. FEBS Lett. 579: 5181-5186, 2005.
Hosaka, M., Watanabe, T., Sakai, Y., Kato, T., *Takeuchi, T.: Interaction between secretogranin III
and carboxypeptidase E facilitates prohormone sorting within secretory granules. J. Cell Science
118: 4785-4795, 2005
*Loftus, B., Anderson, I., Davies, R., Alismark, U. C. M., Samuelson, J., Amedeo, P., Roncaglia, P.,
Berriman, M., Hirt, R. P., Mann, B. J., Nozaki, T., Suh, B., Pop, M., Duchene, M., Ackers, J.,
Tannich, E., Leippe, M., Hofer, M., Bruchhaus, I., Willhoeft, U., Bhattacharya, A., Chillingworth, T.,
Churcher, C., Hance, Z., Harris, B., Harris, d., Jagels, K., Moule, S., Mungall, K., Ormond, D.,
Squares, R., Whitehead, S., Guillen, N., Gilchrist, C., Stroup, S. E., Bhattacharya, S., Lohia, A.,
Foster, P. G., Sicheritz-Ponten, T., Weber, C., Singh, U., Mukherjee, C., Petri, W. A. J., Clark, C. G.,
Embley, T. M., Barrell, B., Fraser, C. M., Hall, N. The genome of the protist parasite Entamoeba
histolytica.: Nature 433: 865-868, 2005.
Beck, D.L., Boettner, D., Dragulev, B., Ready, L., Mackey, A.J., Nozaki, T., Pearson, W.R., *Petri,
Jr., W.A.: Identification and gene expression analysis of a large family of transmembrane kinases
related to the Gal/GalNAc lectin in Entamoeba histolytica. Eukaryot. Cell 4: 722-732, 2005.
Okada, M., Huston, C. D., Mann, B. J., Petri, Jr., W. A., Kita, K., *Nozaki, T.: Proteomic analysis of
phagocytosis in the enteric protozoan parasite Entamoeba histolytica. Eukaryot. Cell 4: 827-831,
2005.
Saito-Nakano, Y., Loftus, B. J., Hall, N., *Nozaki, T.: The diversity of Rab small GTPases in
Entamoeba histolytica. Exp. Parasitol. 110: 244-252, 2005.
Mitra, B. N., Yasuda, T., Kobayashi, S., Satio-Nakano, Y., *Nozaki, T.: Differences in morphology of
phagosomes and kinetics of acidification and degradation in phagosomes between the pathogenic
Entamoeba histolytica and the non-pathogenic Entamoeba dispar. Cell Motil. Cytoskeleton 62:
84-99, 2005.
Nakada-Tsukui, K., Saito-Nakano, Y., Ali, V., *Nozaki, T.: A retromerlike complex is a novel Rab7
effector that is involved in the transport of the virulence factor cysteine protease in the enteric
protozoan parasite Entamoeba histolytica. Mol. Biol. Cell 16: 5294-5303, 2005.
Okada, M., Huston, C. D., Oue, M., Mann, B. J., Petri, Jr., W. A., Kita, K., *Nozaki, T.: Kinetics and
strain variation of phagosome proteins of Entamoeba histolytica by proteomic analysis. Mol.
Biochem. Parasitol. 145: 171-183, 2006.
*Nozaki, T. Nakada-Tsukui, K. Membrane trafficking as a virulence mechanism of the enteric
protozoan parasite Entamoeba histolytica. (review) Parasitol. Res. 98: 179-183, 2006.
Saito, O., Aoe, T., *Yamamoto, T.: Analgesic effects of nonsteroidal antiinflammatory drugs,
acetaminophen, and morphine in a mouse model of bone cancer pain. J Anesth.19(3):218-24, 2005
Doya, H., Ohtori, S., Fujitani, M., Saito, T., Hata, K., Ino, H., Takahashi, K., Moriya, H., *Yamashita,
T.: c-Jun N-terminal kinase activation in dorsal root ganglion contributes to pain hypersensitivity.
Biochem. Biophys. Res. Commun. 335: 132-138, 2005.
Yamashita, T., Fujitani, M., Hata, K., Mimura, F., Taniguchi, J.: Rho/Rho-kinase as potential
therapeutic targets for CNS injury. Gene Therapy and Molecular Biology. 9: 265-268, 2005.
Hata, K., Fujitani, M., Yasuda, Y., Doya, H., Saito, T., Yamagishi, S., Mueller, B.K., *Yamashita, T.:
RGMa inhibition promotes axonal growth and recovery after spinal cord injury. J. Cell Biol. (in
press).
Nishio, Y., Koda, M., Kitajo, K., Seto, M., Hata, K., Taniguchi, J., Moriya, H., Fujitani, M., Kubo, T.,
*Yamashita, T.: Delayed treatment with Rho-kinase inhibitor does not enhance axonal regeneration
or functional recovery after spinal cord injury in rats. Exp. Neurol. (in press).
Hiraga, A., Kuwabara, S., Douya, H., Kanai, K., Fujitani, M., Taniguchi, J., Arai, K., Mori, M.,
Hattori, T., Yamashita, T.: Rho-kinase inhibition enhances axonal regeneration and functional
recovery after peripheral nerve injury. J. Peripher. Nerv. Syst. (in press).
*Saito-Watanabe, T., Ohtori, S., Koda, M., Aoki, Y., Doya, H., Shirasawa, H., Yamazaki, M., Moriya,
H., Takahashi, K., Yamashita, T.: Adenoviral Gene Transfer in the Peripheral Nervous System. J.
Orthopaedic Sci. (in press).
Kano, F., Takenaka, K., *Murata, M. Reconstitution of Golgi disassembly by mitotic Xenopus
egg extracts in semi-intact MDCK cells. in Methods in Molecular Biology (X. Johne Liu ed.)
357-365,2005
Kano, F., Kondo, H., Yamamoto, A., Kaneko, Y., Uchiyama, K., Hosokawa, N., Nagata, K., *Murata,
M. NSF/SNAPs and p97/p47/VCIP135 are sequentially required for cell cycle-dependent
reformation of nthe ER network. Genes to Cells, 10:989-999,2005
東郷建: 細胞膜損傷の修復. 生体の科学 (印刷中), 2006.
Asagiri, M., Sato, K., Usami, T., Ochi, S., Nishina, H., Yoshida, H., Morita, I., Wagner, E. F., Mak,
T. W., Serfling, E., *Takayanagi, H.: Autoamplification of NFATc1 determines its essential role in
bone homeostasis. J. Exp. Med. 202: 1261-1269, 2005.
Saito, K., Araki, Y., Kontani, K., Nishina, H., *Katada, T.: Novel role of the small GTPase Rheb:
Its implication in endocytic pathway independent of the activation of mammalian target of
rapamycin. J. Biochem. 137: 423-430, 2005.
Ishikawa, T., Terai, S., Urata, Y., Marumoto, Y., Aoyama, K., Sakaida, I., Murata, T., Nishina, H.,
Shinoda, K., Uchimura, S., Hamamoto, Y., Okita, K.: Fibroblast growth factor 2 facilitates the
differentiation of transplanted bone marrow cells into hepatocytes. Cell Tissue Res. 14: 1-11,
2005.
Terai, S., Sakaida, I., Nishina, H., Okita, K.: Lesson from the GFP/CCl4 model–Translational
Research Project: the development of cell therapy using autologous bone marrow cells in patients
with liver cirrhosis. J. Hepat. Panc. Surg. 12: 203-207, 2005.
Saito, K., Kajiho, H., Araki, Y., Kurosu, H., Kontani, K., Nishina, H., Katada, T.: Purification and
analysis of RIN family – novel Rab5 GEFs. Methods Enzymol. 403: pp276-283, 2005.
Nishina, H., Katada, T.: The Biological Function of JNKKs (MKK4/MKK7 Knockout Mice). The
JNK Signaling Pathway: pp41-49, 2005.
Nakamura, M., Tanaka, N., Kitamura, N., *Komada, M.: Clathrin anchors deubiquitinating enzymes,
AMSH and AMSH-like protein, on early endosomes. Genes Cells 11: 593-606, 2006
Ohno, N., Terada, N., Yamakawa, H., Komada, M., Ohara, O., Trapp, B. D., *Ohno, S.: Expression
of protein 4.1G in Schwann cells of the peripheral nervous system. J. Neurosci. Res. 64:
10.1002/jnr.20949, 2006
Mizuno, E., Kobayashi, K., Yamamoto, A., Kitamura, N., *Komada, M.: A deubiquitinating enzyme
UBPY
regulates
the
level
of
protein
ubiquitination
on
endosomes.
Traffic
7:
10.1111/j.1600-0854.2006.00452.x, 2006
Watanabe, K., *Nureki, O., Fukai, S., Ishii, R., Okamoto, H., Yokoyama, S., Endo, Y., *Hori, H.:
Roles of conserved amino acid sequence motifs in the SpoU (TrmH) RNA methyltransferase family.
J. Biol. Chem. 280:10368-10377, 2005
Nakanishi, K., Fukai, S., Ikeuchi, Y., Soma, A., Sekine, Y., Suzuki, T., *Nureki, O.: Structural basis
for lysidine formation by ATP pyrophosphatase accompanied with a lysine-specific loop and a
tRNA-recognition domain. Proc. Natl. Acad. Sci. U. S. A. 21:7487-7492, 2005.
Nakanishi, K., Ogiso, Y., Fukai, S., *Nureki, O.: Structural basis for anticodon recognition by
methionyl-tRNA synthetase. Nat. Struct. Mol. Biol. 12:931-932, 2005.
Numata, T., Fukai, S., Ikeuchi, Y., *Suzuki, T., *Nureki, O.: Structural basis for sulfur relay to RNA
mediated by heterohexameric TusBCD complex. Structure 4:357-366, 2005
Igarashi, M., Sato, M.: Glia-derived inhibitors of axonal regrowth: Implication for the molecular
strategy of axonal regeneration (Invited review). Acta Med Biol 53: 65-72, 2005.
Nishikawa, S, Zinkl, G. M., Swanson, R. J., Maruyama, D., and *Preuss, D. (2005) Callose ( -1,3
glucan) is essential for Arabidopsis pollen wall patterning, but not tube growth.
BMC Plant Biol.
5: 22, 2005
Ohsaki, Y., Maeda, T., *Fujimoto, T.: Fixation and permeabilization protocol is critical
for immunolabeling of lipid droplet protein. Histochem. Cell Biol. 124: 445-452, 2005.
*Kogo, H., Ito, S., Moritoki, Y., Kurahashi, H., Fujimoto, T.: Differential expression of caveolin-3 in
mouse smooth muscle cells in vivo. Cell Tissue Res. 324: 291-300, 2006.
Matsuura, R., Kogo, H., Ogaeri, T., Miwa, T., Kuwahara, M., Kanai, Y., Nakagawa, T., Kuroiwa, A.,
Fujimoto, T., *Torihashi, S.: Crucial transcription factors in endoderm and embryonic gut
development are expressed in gut-like structures from mouse ES cells. Stem Cells. 24:624-630,
2006.
Tojo, K., Sekijima, Y., Suzuki T., Suzuki, N., Tomita, Y., Yoshida, K., Hashimoto, T., Shu-ichi Ikeda
S.: Dystonia in a Family with Dyschromatosis Symmetrica Hereditaria. Movement disorders (in
press)
Inagaki, K., *Suzuki, T., Ito, S., Suzuki, N., Fukai, K., Horiuchi, T., Tanaka, T., Manabe, E., Tomita,
Y.: OCA4: Evidence for a Founder Effect for the p.D157N mutation of the MATP gene in Japanese
and Koreans. Pig. Cell Res. 18: 385-388, 2005.
Y., Verma, I.C., Saxena, R., Murase, A., Kono, M., Suzuki, T., Yasue, T., Shibata, S., Sakakibara,
A., Tomita Y.: Establishment of tyrosinase sequence database in normally pigmented Indians and
Japanese for rapid determination of novel mutations. J. Dermatol Sci. 39: 167-173, 2005
Miyamura, Y., Verma , I.C., Saxena, R., Hoshi, M., Murase, A., Nakamura, E., Kono, M., Suzuki, T.,
Yasue, S., Shibata, S., Sakakibara, A., Tomita, Y.: Five novel mutations in tyrosinase gene of
Japanese and Indian patients with oculocutaneous albinism type I (OCAI). J. Invest. Dermatol. 125:
397-398, 2005
Suzuki, T., Tomita Y.: The genetic analysis is essential for determining the type of Oculocutaneous
albinism. (letter) Br. J. Dermatol. 153:1092, 2005
Ito, S., *Suzuki, T., Inagaki, K., Suzuki, N., Takamori, K., Yamada, T., Nakazawa, M., Hatano, M.,
Takiwaki, H., Spritz, R.A., Tomita, Y.: High Frequency of Hermansky-Pudlak Syndrome Type 1
(HPS1) Among Japanese Albinism Patients and Functional Analysis of HPS1 Mutant Protein. J.
Invest. Dermatol. 125: 715-720, 2005
Peduto, L., Reuter, V.E., Sehara-Fujisawa, A., Shaffer, D.R., Scher, H.I., Blobel, C.P.: ADAM12 is
highly expressed in carcinoma-associated stroma and is required for prostate tumor progression.
Oncogene, in press
Yumoto, N., Wakatsuki, S., Sehara-Fujisawa, A*.: The acetylcholine receptor -to- switch occurs
in individual endplates. Biochem. Biophys. Res. Commun, 331: 1522-1527, 2005
Masaki, M., Kurisaki, T., Shirakawa, K., Sehara-Fujisawa, A.*: Role of Meltrin (ADAM12) in
obesity induced by7high-fat diet. Endocrinology, 146(4): 1752-63, 2005
Kawauchi, T., Chihama, K., Nabeshima, Y., *Hoshino, M. : Cdk5 phosphorylates and stabilizes
p27kip1, contributing to actin organization and cortical neuronal migration. Nature Cell Biol. 8:
17-26, 2006.
*Hoshino M., Nakamura S., Mori K., Kawauchi T., Terao M., Nishimura Y.V., Fukuda A., Fuse T.,
Matsuo N., Sone M., Watanabe M., Bito H., Terashima T., Wright C.V.E., Kawaguchi Y., Nakao K.,
Nabeshima Y.: Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum.
Neuron 47: 201-213, 2005.
*Dezawa M., Ishikawa H., Itokazu Y., Yoshihara T., Hoshino M., Takeda S., Ide C., Nabeshima Y.:
Muscle cells derived from bone marrow stromal cells and applied to muscle degeneration. Science
309: 314-317, 2005.
Yoshizawa M., Kawauchi T., Sone M., Nishimura Y.V., Terao M., Chihama K., Nabeshima Y.,
*Hoshino M.: Involvement of a Rac activator, P-Rex1, in neurotrophin-derived signaling and
neuronal migration. J. Neurosci. 25: 4406-4419, 2005.
Nishimura T., Yamaguchi T., Kato K., Yoshizawa M., Nabeshima Y., Ohno S., Hoshino M.,
*Kaibuchi K.: PAR-6-PAR-3 mediates Cdc42 signaling to Rac activation through STEF/Tiam1,
RacGEFs. Nature Cell Biol. 7: 270-277, 2005.
Kawauchi T., Chihama K., Nishimura Y.V., Nabeshima Y.,* Hoshino M.: MAP1B phosphorylation is
differentially regulated by Cdk5/p35, Cdk5/p25 and JNK. Biochem. Biophys. Res. Comm. 331:
50-55, 2005.
*Dezawa M., Kanno H., Hoshino M., Cho H., Matsumoto N., Itokazu Y., Tajima N., Yamada H.,
Sawada H., Ishikawa H., Mimura T., Kitada M., Suzuki Y., Ide C.: Specific induction of neuronal
cells from bone-marrow stromal cells and application for autologous transplantation. J. Clin. Invest.
113: 1701-1710, 2004.
Otsuka, M., Matsumoto, T., Morimoto, R., Arioka, S., Omote, H., *Moriyama, Y.: A human
transpoter protein that mediates the final excretion step for toxic organic cations. Proc. Natl. Acad.
Sci. USA 102: 17923-17928, 2005.
Uehara, S., Jung, S.K., Morimoto, R., Arioka, S., Miyaji, T., Juge, N., Hiasa, M., Shimizu, K.,
Ishimura, A., Otsuka, M., Yamamoto, A., Maechler, P.,*Moriyama, Y.: Vesicular storage and
secretion of L-glutamate from glucagon-like peptide 1-secreting clonal intestinal L cells. J.
Neurochem. 96: 550-560, 2006.
Wei, F.-Y., Nagashima, K., Ohshima, T., Saheki, Y., Lu, Y.-F., Matsushita, M., Yamada, Y.,
Mikoshiba, K., Seino, Y., Matsui, H., *Tomizawa, K.: Cdk5-dependent regulation of
glucose-stimulated insulin secretion. Nature Med. 11: 1104-1108, 2005.
Liu, F., Grundke-Iqbal, I., Iqbal, K., Oda, Y., Tomizawa, K., *Gong C.-X.: Truncation and activation
of calcineurin A by calpain I in Alzheimer disease brain. J. Biol. Chem. 280: 37755-37762, 2005.
Michiue, H., *Tomizawa, K., Matsushita, M., Tamiya, T., Lu, Y.-F., Ichikawa, T., Date, I., Matsui,
H.: Ubiquitination-resistant p53 protein transduction therapy facilitates anti-cancer effect on the
growth of human malignant glioma cells. FEBS Lett. 579: 3965-3969, 2005.
Michiue, H., *Tomizawa, K., Wei, F.-Y., Matsushita, M., Lu, Y.-F., Ichikawa, T., Tamiya, T., Date, I.,
and Matsui, H.: The NH-2-terminal of influenza virus hemagglutinin-2 subunit peptides enhance the
anti-tumor potency of poly-arginine-mediated p53 protein transduction. J. Biol. Chem. 280:
8285-8289, 2005.
Morita, A., Yamashita, N., Sasaki, Y., Uchida, Y., Nakajima, O., Nakamura, F., Yagi, T.,
Taniguchi, M., Usui, H., Katoh-Semba, R., Takei, K., Goshima, Y. : Regulation of
dendritic branching and spine maturation by Semaphorin3A-Fyn signaling. J. Neurosci.,
in press.
Shimamura, M., Shimizu, M., Yagami, T., Funabashi, T., Kimura, F., Kuroiwa, Y., Misu,
Y., Goshima, Y.: l-3,4-Dihydroxyphenylalanine-induced c-Fos expression in the CNS
under inhibition of central aromatic l-amino acid decarboxylase. Neuropharmacology,
in press.
Arimura, N., Menager, C., Kawano, Y., Yoshimura, T., Kawabata, S., Hattori, A., Fukata,
Y., Amano, M., Goshima, Y., Inagaki, M., Morone, N., Usukura, J., Kaibuchi, K.:
Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones. Mol. Cell
Biol. 25:9973-9984, 2005.
Shibakawa YS, Sasaki Y, Goshima Y, Echigo N, Kamiya Y, Kurahashi K, Yamada Y,
Andoh T. Effects of ketamine and propofol on inflammatory responses of primary glial
cell cultures stimulated with lipopolysaccharide. Br. J. Anaesth. 95:803-810, 2005.
Uchida, Y., Ohshima, T., Sasaki, Y., Suzuki, H., Yanai, S., Yamashita, N., Nakamura, F.,
Takei, K., Ihara, Y., Mikoshiba, K., Kolattukudy, P., Honnorat, J., Goshima, Y.:
Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3beta
phosphorylation of CRMP2: implication of common phosphorylating mechanism
underlying axon guidance and Alzheimer's disease. Genes Cells 10(2):165-179, 2005.
Zhang, J., Fujii, S., Wu, Z., Hashioka, S., Tanaka, Y., Shiratsuchi, A., Nakanishi Y., and *Nakanishi,
H.: Involvement of COX-1 and up-regulated prostaglandin E synthases in phosphatidylserine
liposome-induced prostaglandin E2 production by microglia. J. Neuroimmunol. 172: 112-120. 2006
Kuronita, T., Hatano, T., Furuyama, A., Hirota, Y., Masuyama, N., Saftig, P., Himeno, M., Fujita, H.,
*Tanaka, Y.: The NH2-terminal transmembrane and lumenal domains of LGP85 are needed for the
formation of enlarged endosomes/lysosomes. Traffic 6: 895-906, 2005.
Nomura, H., Furuta, A., Tanaka, Y., *Iwaki, T.: Forced retraction of spinal root injury enhances
activation of p38 MAPK cascade in infiltrating macrophages. Neurophathology 25: 37-47, 2005.
Wakana, Y., Koyama, S., Nakajima, K., Hatsuzawa, K., Nagahama, M., Tani, K., Hauri, HP.,
Melancon, P., Tagaya, M.: Reticulon 3 is involved in membrane trafficking between the endoplasmic
reticulum and Golgi. Biochem. Biophys. Res. Commun. 334: 1198-1205, 2005.
Okumura, AJ., Hatsuzawa, K., Tamura, T., Nagaya, H., Saeki, K., Okumura, F., Nagao, K.,
Nishikawa, M., Yoshimura, A., Wada, I.: Involvement of a novel Q-SNARE, D12, in quality control
of the endomembrane system. J. Biol. Chem. 281: 4495-4506, 2006.
Morita, A., Yamashita, N., Sasaki, Y., Uchida, Y., Nakajima, O., Nakamura, F., Yagi, T., Taniguchi,
M., Usui, H., Katoh-Semba, R., Takei, K., Goshima, Y. : Regulation of dendritic branching and spine
maturation by Semaphorin3A-Fyn signaling. J. Neurosci., in press.
Shimamura, M., Shimizu, M., Yagami, T., Funabashi, T., Kimura, F., Kuroiwa, Y., Misu, Y., Goshima,
Y.: l-3,4-Dihydroxyphenylalanine-induced c-Fos expression in the CNS under inhibition of central
aromatic l-amino acid decarboxylase. Neuropharmacology, in press.
Arimura, N., Menager, C., Kawano, Y., Yoshimura, T., Kawabata, S., Hattori, A., Fukata, Y., Amano,
M., Goshima, Y., Inagaki, M., Morone, N., Usukura, J., Kaibuchi, K.: Phosphorylation by Rho
kinase regulates CRMP-2 activity in growth cones. Mol. Cell Biol. 25:9973-9984, 2005.
Shibakawa YS, Sasaki Y, Goshima Y, Echigo N, Kamiya Y, Kurahashi K, Yamada Y, Andoh T.
Effects of ketamine and propofol on inflammatory responses of primary glial cell cultures stimulated
with lipopolysaccharide. Br. J. Anaesth. 95:803-810, 2005.
Uchida, Y., Ohshima, T., Sasaki, Y., Suzuki, H., Yanai, S., Yamashita, N., Nakamura, F., Takei, K.,
Ihara, Y., Mikoshiba, K., Kolattukudy, P., Honnorat, J., Goshima, Y.: Semaphorin3A signalling is
mediated via sequential Cdk5 and GSK3beta phosphorylation of CRMP2: implication of common
phosphorylating mechanism underlying axon guidance and Alzheimer's disease. Genes Cells
10(2):165-179, 2005.
Suzuki, A. and Ohno, S.: The PAR-aPKC system: lesson in polarity. (Review)
J.Cell Sci.
in press
(2006)
Yamanaka, T., Horikoshi, Y., Izumi, N., Suzuki, A., Mizuno, K., Ohno S.: Lgl mediates apical
domain disassembly by suppressing PAR-3/aPKC/PAR-6 complex to orient apical membrane
polarity.
J.Cell Sci.
in press (2006)
Yoshimi, R., Yamaji, S., Suzuki, A., Mishima, W., Okamura, M., Obana, T. Matsuda C., Miwa, Y.,
Ohno, S., Ishigatsubo, Y.: The
-parvin-integrin-linked kinase complex is critically involved in
leukocyte-substrate interaction. J. Immunol.
in press (2006)
Wakazono, Y., Sakurai, T., Ohara-Imaizumi, M., Nagamatsu, S., Yamamoto, S., Terakawa. S.:
Intracellular dynamics observed by mode switching of microscope with a light incidence to the
interface at alternate angles through the ultra high NA objective. Proc. SPIE. 6088: 449-454, 2006.
Yamaguchi, S., Katahira, H., Ozawa, S., Nakamichi, Y., Tanaka, T., Shimoyama, T., Takahashi, K.,
Yoshimoto, K., Ohara-Imaizumi, M., Nagamatsu, S., and Ishida, H., Activators of AMP-activated
protein kinase enhance GLUT4 translocation and its glucose transport activity in 3T3L1 adipocytes.
Am. J. Physiol. Endocrinol. Metab. 289: E643-649, 2005.
今泉美佳 永松信哉 インスリン開口放出のリアルタイム可視化技術 日本薬理学会雑誌 126:
399-405,2005.
今泉美佳 永松信哉 インスリン顆粒開口分泌とその異常
分子糖尿病学の進歩-2006-基礎から
臨床まで 10-19, 金原出版 2006.
Matsuda, S., Kamiya, Y., *Yuzaki, M.: Roles of the N-terminal domain on the functions and
quaternary structure of the ionotropic glutamate receptor. J. Biol. Chem.
280:
20021-20029,
2005.
Kakegawa, W., *Yuzaki, M.: Novel mechanism underlying AMPA receptor trafficking during
cerebellar long-term potentiation. Proc. Natl. Acad. Sci. USA, 102: 17846–17851, 2005.
Hozumi, S., Maeda, R., Taniguchi, K., Sasamura, T., Spéder, P., Noselli, S., Aigaki, T., Murakami, R.
and Matsuno, K.: A Drosophila unconventional myosin reverses the default handedness in visceral
organs. Nature, in press, 2006.
Fuwa, T. J., Hori, K., Sasamura, T., Higgs, J., Baron, M. and Matsuno, K.: The first deltex null
mutant indicates tissue-specific deltex-dependent Notch signaling in Drosophila. Mol. Genet. and
Genom., in press, 2006.
Ishikawa, H. O., Higashi, S., Ayukawa, T, Sasamura, T., Aoki, K., Ishida N., Sanai, Y. and Matsuno,
K.: A Drosophila model of congenital disorder of glycosylation IIc implicates the deficiency of
Notch signaling in its pathogenesis. Proc. Natl. Acad. Sci. USA 102, 18532-18537, 2005.
He, Y., Sugiura, R., Ma, Y., Kita, A., Deng, L., Takegawa, K., Matsuoka, K., Shuntoh, H., Kuno, T.:
Genetic and Functional Interaction between Ryh1 and Ypt3: two Rab GTPases that Function in S.
pombe Secretory Pathway. Genes-Cells, in press 2006.
Deng, L., Sugiura, R., Ohta, K., Tada, K., Suzuki, M., Hirata, M., Nakamura, S., Shuntoh, H., Kuno,
T.: Phosphatidylinositol-4-phosphate-5-kinase regulates fission yeast cell integrity through a
phospholipase C-mediated protein kinase C-independent pathway. J. Biol. Chem. 280:27561-27568,
2005.
Sio, SO., Suehiro, T., Sugiura, R., Takeuchi, M., Mukai, H., Kuno, T.: The role of the regulatory
subunit of fission yeast calcineurin for in vivo activity and its relevance to FK506 sensitivity. J. Biol.
Chem. 280: 12231-12238, 2005.
Matsumaru, T., Sugiura, R., Sakai, K., Igarashi, T., Kuno, T.: Comparison of Toxicity and
Toxicokinetics/Pharmacokinetics of an α1L-adrenoceptor Agonist in Rats and Rhesus monkeys. J.
Pharmacol. Sci. 97:273-83, 2005.
Kuroyanagi, M., Yamada, K., Hatsugai, N., Kondo, M., Nishimura, M., Hara-Nishimura, I.: VPE is
essential for mycotoxin-induced cell death in Arabidopsis thaliana. J. Biol. Chem. 280:
32914-32920, 2005.
Maehr, R., Hang, H. C., Mintern, J. D., Kim, Y.-M., Cuvillier, A., Nishimura, M., Yamada, K.,
Shirahama-Noda, K., Hara-Nishimura, I., Ploegh, H. L.: Asparagine endopeptidase is not essential
for class II MHC antigen presentation but is required for processing of chathepsin L in mice. J.
Immunol. 174: 7066-7074, 2005.
Nakaune, S., Yamada, K., Kondo, M., Kato, T., Tabata, S., Nishimura, M., Hara-Nishimura, I.: A
development. Plant Cell 17: 876-887, 2005.
Yamada, K., Fuji, K., Shimada, T., Nishimura, M., Hara-Nishimura, I.: Endosomal proteases
facilitate the fusion of endosomes with vacuoles at the final step of the endocytotic pathway. Plant J.
41: 888-898, 2005.
Yamada, K., Shimada, T., Nishimura, M., Hara-Nishimura, I.: A VPE family supporting various
vacuolar functions in plants. Physiol. Plant. 123: 369-375, 2005.
Hara-Nishimura, I., Hatsugai, N., Nakaune, S., Kuroyanagi, M., Nishimura, M.: Vacuolar processing
enzyme: an executor of plant cell death. Curr. Opin. Plant Biol. 8: 404-408, 2005.
Tanaka, M., Nagano-Fujii, M., Deng, L., Ishido, S., Sada, K. and *Hotta, H.: Single-point mutation
of hepatitis C virus NS3 that impaired p53 interaction and anti-apoptotic activity of NS3. Biochem.
Biophys. Res. Commun. 340: 792-799, 2006.
Ichimaru, N., Murai, M., Abe, M., Hamada, T., Makino, S., Nishioka, T., Makabe, H., Makino, A.,
Kobayashi, T.
-Acetogenins: A Novel Type of Inhibitors
of Bovine Heart Mitochondrial Complex I. Biochemistry 44:816-825, 2005.
Sato, H., Maeba, T., Yanase, R., Yamaji-Hasegawa, A., Kobayashi, T., Chida, N.: Total synthesis and
biological activities of (+)-sulfamisterin (AB5366) and its analogues. J. Antibiot. 58:37-49, 2005.
Kobayashi, T., Makino, A., Ishii K.: Vital staining of cells with fluorescent lipids. Cell Biology : A
Laboratory Handbook Chapter 2.3.4 (Cellis JE Ed.) Elsevier, Burlington, 2005.
Sakuraba, H., Chiba, Y., Kotani, M., Kawashima, I., Ohsawa, M., Tajima, Y., Takaoka, Y., Jigami, Y.,
Takahashi, H., Hirai, Y., Shimada, T., Hashimoto, Y., Ishii, K., Kobayashi, T., Watabe, K., Fukushige,
T., Kanzaki, T.: Corrective
-galactosidase having N-linked
sugar chains suitable for lysosomal delivery of Fabry mice. J. Hum. Genet. in press, 2006.
Makino, A., Ishii, K., Murate, M., Hayakawa, T., Suzuki, Y., Suzuki, M., Ito, K., Fujisawa, T.,
Matsuo,
H.,
Ishitsuka,
R.,
Kobayashi,
T.:
D-threo-1-phenyl-2-decanoylamino-3-morpholina-1-propanol alters cellular cholesterol homeostasis
by modulating endosome lipid domains. Biochemistry in press, 2006.
Besson, N., Hullin-Matsuda, F., Makino, A., Murate, M., Lagarde, M., Pageaux, J-F., Kobayashi, T.,
Delton-Vandenbroucke, I.: Selective incorporation of docosahexaenoic aicd in cultured THP-1
macrophages. Lipids in press, 2006.
Kobayashi, T., Yamaji-Hasegawa A.: Lysenin: a new probe for sphingomyelin. Sphingolipid Biology
(Hirabayashi, Igarashi, Merrill eds.) Springer, Tokyo. in press, 2006.
Kuroda, T. S., *Fukuda, M.: Functional analysis of Slac2-c/MyRIP as a linker protein between
melanosomes and myosin VIIa. J. Biol. Chem. 280: 28015-28022, 2005.
Mîinea, C. P., Sano, H., Kane, S., Sano, E., Fukuda, M., Peränen, J., Lane, W. S., *Lienhard, G. E.:
AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase activating
protein domain. Biochem. J. 391: 87-93, 2005.
Roggero, C. M., Tomes, C. N., De Blas, G. A., Castillo, J., Michaut, M. A., Fukuda, M., *Mayorga, L.
S.: Protein Kinase C-mediated phosphorylation of the two polybasic regions of synaptotagmin VI
regulates their function in acrosomal exocytosis. Dev. Biol. 285: 422-435, 2005.
Iezzi, M., Eliasson, L., Fukuda, M., *Wollheim, C. B.: Adenovirus-mediated silencing of
Synaptotagmin 9 inhibits Ca2+-dependent insulin secretion in islets. FEBS Lett. 579: 5241-5246,
2005.
*Saxena, S., Singh, M., Engisch, K., Fukuda, M., Kaur, S.: Rab proteins regulate epithelial sodium
channel activity in colonic epithelial HT-29 cells. Biochem. Biophys. Res. Commun. 337:
1219-1223, 2005.
*Swiatecka-Urban, A., Brown, A., Moreau-Marquis, S., Renuka, J., Coutermarsh, B., Barnaby, R.,
Karlson, K. H., Flotte, T. R., Fukuda, M., Langford, G. M., Stanton, B. A.: The short apical membrane
half-
-cystic fibrosis transmembrane conductance regulator (CFTR) results from
-CFTR in polarized human airway epithelial cells. J. Biol. Chem.
280: 36762-36772, 2005.
*Fukuda, M., Imai, A., Nashida, T., Shimomura, H.: Slp4-a/granuphilin-a interacts with syntaxin-2/3
in a Munc18-2-dependent manner. J. Biol. Chem. 280: 39175-39184, 2005.
Tsuboi, T., *Fukuda, M.: The C2B domain of rabphilin directly interacts with SNAP-25 and regulates
the docking step of dense core vesicle exocytosis in PC12 cells. J. Biol. Chem. 280: 39253-39259,
2005.
Kuroda, T. S., Itoh, T., *Fukuda, M.: Functional analysis of Slac2-a/melaonophilin as a linker protein
between Rab27A and myosin Va in melanosome transport. Methods Enzymol. 403: 419-431, 2005.
Kuroda, T. S., *Fukuda, M.: Identification and biochemical analysis of Slac2-c/MyRIP as a Rab27A-,
myosin Va/VIIa-, and actin-binding protein. Methods Enzymol. 403: 431-444, 2005.
*Fukuda, M., Kanno, E.: Analysis of the role of Rab27 effector Slp4-a/granuphilin-a in dense-core
vesicle exocytosis. Methods Enzymol. 403: 445-457, 2005.
*Fukuda, M.: Assay and functional interactions of Rim2 with Rab3. Methods Enzymol. 403: 457-468,
2005.
*Fukuda, M., Yamamoto, A.: Assay of Rab binding specificity of rabphilin and Noc2: Target
molecules for Rab27. Methods Enzymol. 403: 469-481, 2005.
Herrero-Turrión, M. J., Fukuda, M., *Mollinedo, F.: Cloning and genomic characterization of sytdep,
a new synaptotagmin XIV-related gene. Biochem. Biophys. Res. Commun. 340: 386-394, 2006.
*Fukuda, M.: Distinct developmental expression of synaptotagmin I and IX in the mouse brain.
NeuroReport 17: 179-182, 2006.
ano, H., Yamamoto-Hino, M., Abe, M., Kuwahara, R., Haraguchi, S., Kinoshita-Toyoda, A., Toyoda, H., *
Goto, S.: Distinct functional units of the Golgi complex in Drosophila cells. Proc. Natl. Acad. USA 102:
13467-13472, 2005.