COMMUNICABLE DISEASE MANUAL POLICIES/PROCEDURES LEPTOSPIROSIS OBJECTIVE: Control and management of Leptospirosis DESCRIPTION: A group of zoonotic bacterial diseases, with protean manifestations (influenzalike). Excreted in urine of animals and their carcasses. Leptospirosis occurs as two clinically recognizable syndromes; anicteric and icteric. 90% will have anicteric illness (influenza-like), however, 10% will be severely ill with icteric form (jaundice, abnormal liver function tests, liver failure and renal failure). Causative agent is the spirochete Leptospira interrogans. Mode of transmission is via contact of skin or mucous membranes with water, moist soil, or vegetation contaminated by urine of infected wild or domestic animals; ingestion of food contaminated with urine of infected animals; and inhalation of droplet aerosols of contaminated fluids. Direct transmission from person-toperson is rare. Incubation period is usually 7 to 13 days, with a range of 2 to 26 days. EQUIPMENT: MDSS User Manual (disease specific form found in MDSS). Microbiology/Virology Test Requisition, MDCH Web site at www.michigan.gov/cdinfo and CDC Web site at www.cdc.gov/diseasesconditions/az/a.html. POLICY: Legal Responsibility: Michigan's communicable disease rules of Act No. 368 of the Public Acts of 1978, as amended, being 333.5111 of the Michigan Compiled Laws. Follow-up time within 72 hours post referral AND ENTER INTO MDSS WITHIN 24 HOURS OF RECEIPT OF REFERRAL. PROCEDURE: A. B. C. Case Investigation: 1. Referral received per phone call, laboratory results, or automatically through MDSS. 2. Document all case investigation proceedings. 3. Contact MD and/or client to start process of completing disease specific form in MDSS. Lab Criteria for Diagnosis: 1. Diagnosis is confirmed by rising titers in serologic tests, such as the microscopic agglutination test (MAT), and by isolation of leptospires from blood (first 7 days) or CSF (4-10 days) during acute illness and the urine after the first week and during convalescence. 2. Serology will only be done if there is prior approval from MDCH Microbiology Lab 1-517-335-8067. Control Measures: 1. D:\106736305.docPage 1 of 2 Preventive 2. D. 2. 3. D:\106736305.docPage 2 of 2 Immunization of farm animals and pets. Control rodents in human habitations. Segregate infected domestic animals. b. Educate public on modes of transmission and avoid swimming or wading in potentially contaminated waters. c. Wear proper protection when work requires exposure. Control of Patient a. Investigation of contacts and source. b. Isolation of blood/body fluid. MDSS Case Report: 1. RESOURCES: a. Complete case investigation using disease specific form in MDSS. Notify CD Supervisor that the case report is ready for review. PHN will be notified if corrections are needed prior to closing case in MDSS. CD Supervisor reviews case for completeness and closes MDSS case report. Current Red Book Current Control of Communicable Diseases Manual Current disease specific “Fact Sheet” Websites: www.cdc.gov/diseasesconditions/az/a.html www.michigan.gov/cdinfo