GEOSCI/ENVIRON/BIOLOGY (100 level) The Microbial World: How Unseen Organisms Shape Our Planet (4 cr) Prereqs: none. Short course description This course examines how microorganisms shape the world around us, both throughout the Earth’s history and today. Major topics include the origin and evolution of life, the interplay between microbes and the environment, roles of microbes in global warming, and applications of microbiology in biotechnology and energy. Long description This course seeks to introduce students to the critical yet commonly overlooked roles that tiny, unseen organisms play in environmental, global, and human health. The common theme will be in examining how microorganisms shape the world around us, both throughout the Earth’s history and today. Specific topics to be covered include the origin and evolution of life, the interplay between microbes and the environment, and current topics in biotechnology, energy, global warming, and the environment. Emphasis will be placed on considering science to be of tangible and practical importance to modern society. Discussion sessions will allow for discussion of topics covered in lecture, exercises aimed at reinforcing primary concepts and methods, and review of exams and quizzes. Grades will be based on regular quizzes, one midterm exam, a final exam, and discussion participation. This course is primarily intended for non-science majors. Students with interests in evolution, environmental science, and current controversial topics such as the origin of life, global climate change, and biotechnology are encouraged to enroll. Textbook: Brock Biology of Microorganisms, 11th edition, by Michael Madigan and John Martinko Syllabus: Part I. INTRODUCTION: This section will provide a broad introduction to microbiology that will serve as a foundation for understanding material presented in parts II through IV. Lectures 1 and 2 will outline the scope of the course, introduce students to the pervasive and ubiquitous nature of microbes on our planet, and provide material aimed at building an appreciation for the scales and metrics (both physical and temporal) that are pertinent to geology and microbiology. Lectures 3 through 6 entail a basic introduction to microbial physiology and metabolism and will highlight how the biological requirements of microbes are linked to the impact that they have on their environment. 1. 2. 3. 4. 5. 6. Course overview Introduction to microbiology: history, scales, & taxonomy Microbial physiology Metabolism I Metabolism II Metabolism III Part II. THE COEVOLUTION OF EARTH AND LIFE: Part II will focus on the coevolution of the biosphere and geosphere. Lecture 7 will cover theories of the origin and early history of life on Earth, including a critical review of current evidence and controversies supporting and surrounding these theories. Lectures 8 – 10 present concepts of biological diversity, methods for assessing phylogenetic relationships among organisms, and an examination of how that has led the current view of the tree of life. Lectures 11 and 12 will highlight the central role of microbes in major events throughout Earth’s history such as the oxygenation of the atmosphere and formation of geological deposits. 7. The Origin and early evolution of life on Earth 8. The tree of life I 9. The tree of life II 10. The tree of life III 11. Microbes and Earth History 12. Geomicrobiology: how and why microbes make and dissolve rocks Part III. ENVIRONMENTAL MICROBIOLOGY & MICROBIAL ECOLOGY: Part III surveys microorganisms in their natural habitats with an emphasis on the interplay between organism and environment. Lectures 13 and 14 introduce the methods and fundamentals that encompass the study of microbes in the nature. Lectures 15 – 21 provide case studies for examining these principles of microbial ecology, from marine, terrestrial, and atmospheric environments to symbioses between microbes and higher organisms. Lecture 19 will address how microbiological processes (covered in lectures 15 – 18) that take place on molecular scales have important impacts on global scales. In lectures 22 and 23 the limits of life (physical and energetic) on Earth will be explored and implications in terms of the prospects and search for life on other planets will be reviewed. 13. The tools of environmental microbiology 14. Microbial ecology & communities 15. Marine microbiology I 16. Marine microbiology II 17. Atmospheric and freshwater microbiology: air, lakes, ponds, & streams 18. Terrestrial environments 19. Microbes & global climate change 20. Symbioses 21. Humans as symbiotic hosts: microbes in health & disease 22. Life in extreme environments 23. Astrobiology Part IV. APPLIED MICROBIOLOGY: Part IV surveys applied and biotechnological aspects of the microbial world in the context of challenges associated with human population growth, emerging infectious disease, energy, and the environment. Lecture 24 covers the challenges and opportunities that microbes bring to the impact of human activities on the environment, including bioremediation of organic and metal pollution. Lecture 25 reviews the microbiology of food and beverage production, both throughout history and in the modern food industry. Lecture 26 addresses the broad applications of microbes in drug discovery, industry, and biotechnology, and in lecture 27 these applications are extended to the current crisis revolving around energy and global warming. Lecture 28 will synthesize principles covered throughout the course, and broad conclusions regarding the microbial world will be drawn. 24. Corrosion, bio-fouling, & bioremediation 25. The microbiology of food & beverage 26. Pharmaceutical & industrial microbiology; biotechnology 27. Microbes & the energy crisis 28. Review, Synthesis, & Conclusions