Biology 210 Exam 4 Study Guide (Chapters 15-17) Chapter 15 INTRODUCTION 1. Provide an overview of the three basic functions of the sensory, motor, and integrative systems of the nervous system. SENSATION 2. Define and compare sensation and perception. Sensory Modalies 3. Define sensory modality, give examples, and indicate the unique relationship to impulses transmitted along specific pathways. The Process of a Sensation 4. Generally examine the four requisite events for a stimulus to become a sensation. Sensory Receptors Types of Sensory Receptors 5. Describe the types of receptors in terms of association with general or special systems, location, and stimulus type. Adaptation in Sensory Receptors 6. State what is meant by adaptation of receptors and provide examples of slow and rapidly adapting receptors. SOMATIC SENSATIONS 7. Note the general location and nature of somatic receptors. 8. Identify the cutaneous sensation modalities. Tactile Sensations 9. Identify the tactile sensations, how they are detected, and the receptors involved. 10. Describe the touch receptors and how they respond to a stimulus. 11. Define and compare the sensations of pressure and vibration. 12. Define and compare the sensations of itch and tickle. Thermal Sensations 13. Identify the thermal sensations, their receptors, and the receptor locations. Pain Sensations 14. Describe the function of pain. 15. Identify the pain receptors, their location, and what stimulates them. Types of Pain 16. Distinguish between fast and slow pain and among superficial somatic, deep somatic, and visceral pain. Localization of Pain 17. Discuss the localization of pain, including referred pain and phantom limb pain. 18. Describe how analgesic drugs provide relief from pain. Proprioceptive Sensations 19. Identify the types of proprioception and indicate their neural pathways, areas of CNS processing, and function. Muscle Spindles 20. Describe the architecture and reflexive operation of the muscle spindle apparatus with their neural links to the CNS and skeletal muscle. Tendon Organs 21. Describe the architecture and reflexive operation of the tendon organs with their neural links to the CNS and skeletal muscle. Joint Kinesthetic Receptors 22. Discuss the location, nature, and purpose of joint kinesthetic receptors. MOTOR CORTEX MAPS IN THE CEREBRAL CORTEX 23. Examine the samatic sensory and somatic motor maps in the cerebral cortex. 24. Demonstrate the relationship of the proportion of sensory representation on the cortical surface with receptor density on the body surface. 25. Describe the relationship between the number of motor units going to an area of the body and the amount of surface area of the primary motor cortex that controls that body part SOMATIC SENSORY PATHWAYS 26. Discuss the general neuronal components of the somatic sensory pathways from receptors to cerebral cortex. Posterior Column-Medial Lemniscus Pathway to the Cortex 27. Discuss the neuronal components and functions of the posterior column-medial lemniscus pathway. Anterolateral Pathways to the Cortex 28. Discuss the neuronal components and functions of the anterolateral pathway. Somatic Sensory Pathways to the Cerebellum 29. Describe the neural paths that lead from receptors to the cerebellum and how they are structurally different from the spinothalamic tracts. 30. Discuss how Treponema pallidum impacts the operation of the spinocerebellar tract. SOMATIC MOTOR PATHWAYS 31. List the neural circuits termed the somatic motor pathways. Organization of Upper Motor Neuron Pathways 32. Differentiate between direct motor pathways and indirect motor pathways. 33. Describe the difference in paralysis symptoms with damage to upper versus lower motor neurons. Direct Motor Pathways 34. Illustrate the neural pathway segments of three major representations of the descending pyramidal-corticospinal tract and indicate their distinctive functions. 35. Describe the effects of ALS on the motor pathway neruons. Indirect Pathways 36. List the central nervous system components that are involved with processing of motor information of the extrapyramidal pathways and the tracts of the spinal cord where they connect. Modulation of Movement by the Basal Ganglia 37. Explain how the basal ganglia are involved in motor responses. 38. Examine the effects of Parkinson disease and Huntington disease on the basal ganglia. Modulation of Movement by the Cerebellum 39. Discuss the four principle operations of the cerebellum in the coordination of conscious and subconscious skilled muscle movements. 40. Describe ataxia and intention tremors as symptoms of damage to the cerebellum. INTEGRATIVE FUNCTIONS OF THE CEREBRUM 41. List the major integrative functions of the cerebrum. Wakefulness and Sleep 42. Describe the role of the hypothalamus in the wakefulness and sleep cycle. The Role of the Reticular Activating System in Awakening 43. Describe the role of the reticular activating system in arousal and consciousness. Sleep 44. Discuss the characteristics of rapid eye movement (REM) sleep and the difference compared to the stages of non-REM sleep. Learning and Memory 45. Show how learning and memory are related and the areas of the brain that are though to be involved. 46. Examine the theoretical mechanisms of short-term and long-term memory. DISORDERS: HOMEOSTATIC IMBALANCES 47. Discuss spinal cord injury and Parkinson disease in terms of cause, symptoms, and prognosis. MEDICAL TERMINOLOGY 48. Define the medical terminology associated with the sensory, motor, and integrative systems. Chapter 16 INTRODUCTION 1. Briefly describe the receptors for the special senses. OLFACTION: SENSE OF SMELL 2. Discuss the interconnection of the senses of smell and taste. Anatomy of Olfactory Receptors 3. Discuss the anatomic relation of cells in the olfactory mucosa and describe the cellular parts with respect to function. Physiology of Olfaction 4. Describe the sequence of events in which a molecule that comes in contact with mucus of the epithelium initiates an action potential. Odor Thresholds and Adaptation 5. Explain the result of olfactory nerve adaptation on sensory nerve output and how it is useful in discriminative sensory sensitivity. Olfactory Pathway 6. Describe the neural links from the bipolar olfactory receptor to their destinations in specific functional areas of the brain. 7. Define hyposmia and state its causes. GUSTATION: SENSE OF TASTE 8. Discuss the general similarities and differences in operation of the gustatory and olfactory systems, then relate how they work together. Anatomy of Taste buds and Papillae 9. Describe the organization and functional parts of the cells within the various taste buds, indicating the differing cellular duties and etiological transformations. Physiology of Gustation 10. Describe the means by which the binding of a dissolved molecule in saliva generates a postsynaptic potential in the primary sensory neuron. 11. Describe how the gustatory system discriminates among hundreds of different tastes with only four types of taste receptors. Taste Thresholds and Adaptation 12. Discuss how the taste threshold changes with adaptation. Gustatory Pathway 13. Indicate which cranial nerves conduct taste impulses from separate regions of the tongue to specific areas of the brain. 14. Describe tase aversion and correlate this phenomenon to survival. VISION Accessory Structures of the Eye Eyelids 15. Describe the structures of the eyelids and their functions. Eyelashes and Eyebrows 16. Describe the eyelashes and eyebrows and their functions. Lacrimal Apparatus 17. Describe the structures of the lacrimal apparatus and their functions. Extrinsic Eye Muscles 18. Identify the extrinsic eye muscles and their functions. Anatomy of the Eyeball Fibrous Tunic 19. Describe the tissue configurations and related jobs of the components of the fibrous tunic. 20. Discuss why there are relatively few medical problems with transplantation of a cornea compared with other body tissues. Vascular Tunic 21. Describe the structural constituents of the three regions of the vascular tunic, while emphasizing how these allow performance of their distinct duties. Retina 22. Describe the major features and layers of the nervous tunic. 23. Discuss the positions of extensions and soma of two types of photo- receptor cells and three varieties of retinal neurons that compose the numerous layers within the retina. 24. Discuss the general purpose of the different retinal cells. Lens 25. Describe the structure and function of the lens. Interior of the Eyeball 26. Describe the materials that occupy the cavities and chambers of the inner eye, and state how the materials support the operation of the eye. 27. Discuss age related macular disease and examine its effects on vision. Image Formation 28. Discuss how components of the eyeball mimic the parts of a camera to perform the three basic processes in properly focusing light on the retina. Refraction of Light Rays 29. Discuss how the bending of light as it passes through the differing densities of transparent materials of the eye is used to direct the rays from objects of varying distance to focus on the retina. Accommodation and the Near Point of Vision 30. Demonstrate how the iris, lens, and extrinsic eye muscles operate in order to converge the light from a near object onto the retina. 31. Examine the effect on image formation when there are abnormal changes in the structure of the cornea and lens. 32. Discuss age related changes in elasticity and their effects on accomodation as seen in presbyopia. Refraction Abnormalities 33. List and discuss the refraction abnormalities. Constriction of the Pupil 34. Outline the components of the iris control mechanism, and their operation and purpose in altering the diameter of the pupil. Convergence 35. Illustrate how and why the relative forward angle of the eyes varies as an object of interest changes distance. Physiology of Vision Photoreceptors and Photopigments 36. Describe the definitive structures and operations of rod and cone photoreceptors as well as the location and differences between photopigments. 37. List the steps of the configuration changes that occur to the photopigments upon absorption of a photon. Light and Dark Adaptation 38. Indicate how the timing of photopigment regeneration leads to different capacities in rods and cones to adapt to changes in light intensity. Release of Neurotransmitters by Photoreceptors 39. Discuss the sequence of interactions between photopigments, enzymes, sodium channels, photoreceptor membrane potential, glutamate release, and changes in the membrane potential of connected bipolar cells. Visual Pathway 40. Mention that the signal produced by the photoreceptors is progressively integrated as it moves through the circuits leading to the brain. Processing of Visual Input in the Retina 41. Discuss how the type of circuit connections of rods and cones to other retinal neurons dictates differences in light sensitivity and clarity of the image invoked by the two types of photoreceptors. Brain Pathway and Visual Fields 42. Diagram the relationship that results in stereoscopic vision from light originating from specific visual fields with the area of the retina that receives it and the alternate pathways of the associated neurons. HEARING AND EQUILIBRIUM Anatomy of the Ear External (Outer) Ear 43. Describe the tissue structures and functions of the auricle and auditory canal. Middle Ear 44. Discuss the anatomy, operations, and functions of middle ear structures from the tempanic membrane to the oval window. 45. Explain why the ossicles amplify the force of vibrations by a factor of thirty from the eardrum to the stapes. 46. State some functional responsibilities of internal auditory tube. Internal (Inner) Ear 47. Illustrate how the bony and membranous labyrinths fit together to form the modules of the semicircular canals, vestibule, and cochlear apparatus. 48. Examine the specialized structures of the sensory mechanisms of the semicircular canals, vestibule, and cochlear apparatus. Nature of Sound Waves 49. Establish the physical relations of sound wave length to frequency and pitch, and amplitude to loudness measured in decibels. 50. Describe how loud sounds damage hair cells. Physiology of Hearing 51. Discuss the principal structures and events that transform differing sound vibration frequencies into impulses traveling along separate cochlear neurons, which are involved with the physiology of hearing. Auditory Pathway 52. Describe the components of the auditory pathway. 53. Discuss how cochlear implants can be used for people with deafness due to injury to hair cells. Physiology of Equilibrium 54. Distinguish between the two kinds of equilibrium. Otolithic Organs: Saccule and Utricle 55. Describe the cellular and extracellular constituents of the maculae, and the relative spacial position of these otoliths organs with the saccule and utricle. 56. Discuss how the otoliths work with the cilia of the macular hair cells to indicate relative orientation to gravity and direction of acceleration. Semicircular Ducts 57. Describe how the fluid of the semicircular canals temporarily moves against the cupula of the ampula to incite impulses that indicate three dimensions of rotational movement. Equilibrium Pathways 58. Define the distribution of the cochlear and vestibular components of cranial nerve VI to the nuclei for vision and head orientation, and to the cerebellum for integration with information on movement control. DEVELOPMENT OF THE EYES AND EARS Eyes 59. Describe the embryological development of the eyes. Ears 60. Describe the embryological development of the ears. DISORDERS: HOMEOSTATIC IMBALANCES 61. Describe the causes and symptoms of cataracts, glaucoma, deafness, Menier’s disease, and otitis media. MEDICAL TERMINOLOGY 62. Define medical terminology associated with sense organs. Chapter 17 INTRODUCTION 1. Survey the general way in which the autonomic nervous system operates to regulate the activities of smooth muscle, cardiac muscle, and glands to maintain homeostasis. COMPARISON OF SOMATIC AND AUTONOMIC NERVOUS SYSTEMS 2. Compare the structural and functional differences between the somatic and autonomic nervous systems. ANATOMY OF AUTONOMIC PATHWAYS 3. Distinguish between the pre- and postganglionic neurons. Preganglionic Neurons 4. Specify the different origins and destination ganglia for the sympathetic (thoracolumbar) and parasympathetic (craniosacral) preganglionic neurons. Autonomic Ganglia 5. Describe the differing locations of the ganglia of the sympathetic and parasympathetic systems. Autonomic Plexuses 6. Discuss the location and composition of the autonomic plexuses. Postganglionic Neurons 7. Compare the differing ratio of pre- to postganglionic neurons of the sympathetic and parasympathetic systems, as well as their distinctive distribution to organs. Structure of the Sympathetic Division 8. Illustrate and define the structures of rami, ganglia, and plexuses along the path of sympathetic nerves from the CNS to their respective effectors. 9. Describe the cause and symptoms of Horner’s syndrome. Structure of the Parasympathetic Division 10. Illustrate and define the structures of cranial nerves and ganglia along the path of parasympathetic nerves from the CNS to their respective effectors. ANS NEUROTRANSMITTERS AND RECEPTORS 11. Identify the chemical nature of the autonomic neurotransmitter receptors and their location. Cholinergic Neurons and Receptors 12. Identify the cholinergic neurons, receptors, and neurotransmitters. 13. Describe the effects of acetylcholine as a cholinergic neuron neurotransmitter. Adrenergic Neurons and Receptors 14. Identify the adrenergic neurons, receptors, and neurotransmitters. 15. Describe the effects of norepinephrine as an adrenergic neuron neurotransmitter. Receptor Agonists and Antagonists 16. Identify certain cholinergic and adrenergic agonists and antagonists and their actions. PHYSIOLOGICAL EFFECTS OF THE ANS 17. Emphasize that most organs receive innervation from both ANS divisions that have opposing and balancing effects, which depend on the neurotransmitter released and the particular receptor on the organ. 18. Indicate which organs are innervated solely by the sympathetic or parasympathetic ANS divisions. Sympathetic Responses 19. Discuss the primary purpose of the sympathetic division and the general body functions it directs. 20. Describe Raynaud’s disease and describe its symptoms. Parasympathetic Response 21. Discuss the primary purpose of the parasympathetic division and the general body functions it directs. INTEGRATION AND CONTROL OF AUTONOMIC FUNCTIONS Autonomic Reflexes 22. Describe the ANS and CNS components involved in a visceral autonomic reflex. Autonomic Control by Higher Centers 23. Explain the relationship of the hypothalamus, brain stem nuclei, limbic system, and cerebrum to the autonomic nervous system. 24. Define autonomic dysreflexia and describe its effects. FOCUS ON HOMEOSTASIS: THE NERVOUS SYSTEM 25. Examine the role of the nervous system in maintaining homeostasis