Curriculum Vitae - Queen`s University Belfast

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Dr Jiawu Zhao
Education
2010 - 2014 Queen’s University Belfast, Centre for Vision and Vascular Science
 Doctor of Philosophy
 Supervisors: Prof. Heping Xu, Dr Mei Chen, Prof. Alan Stitt
 Project: study the mechanisms of inflammation-mediated retinal angiogenesis
 Funding: NERC
2009 - 2010 University of Glasgow
 Master of Research
 Biomedical Sciences
2003 - 2007 University of Manchester
 Bachelor of Science
 Pharmacology and Immunology
Research Experience
2014-present Queen’s University Belfast, Centre for Experimental Medicine
 Postdoctoral Research Fellow
 Supervisor: Prof. Heping Xu
 Project: explore the roles of myeloid cells in retinal inflammation
 Funding: Novartis
Publications:
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Reduced Inflammation and Angiogenesis in CCL2-/-CX3CR1gfp/gfp Mice in the model of
Experimental Autoimmune Uveoretinitis (EAU) (in preparation)
Zhao J, Chen M, Xu H
Complement expression in retinal pigment epithelial cells is modulated by activated
macrophages. Experimental eye research 112, 93-101 (2013)
Luo C, Zhao J, Madden A, Chen M, Xu H
Age- and light-dependent development of localised retinal atrophy in CCL2(-/-)
CX3CR1(GFP/GFP) mice. Plos One 8, e61381 (2013).
Chen M, Hombrebueno JR, Luo C, Penalva R, Zhao J, Colhoun L, Pandi SP, Forrester JV,
Xu H
Para-inflammation-mediated retinal recruitment of bone marrow-derived myeloid cells
following whole-body irradiation is CCL2 dependent. Glia 60, 833-842 (2012)
Chen M, Zhao J, Luo C, Pandi SP, Penalva RG, Fitzgerald DC, Xu H
Persistent inflammation subverts thrombospondin-1-induced regulation of retinal
angiogenesis and is driven by CCR2 ligation. American Journal of Pathology 180,
235-245 (2012)
Chen M, Copland DA, Zhao J, Liu J, Forrester JV, Dick AD, Xu H
Conference presentations:
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Retinal pigment epithelial cells regulate macrophage phenotypes and functions
Zhao J, Luo C, Liu J, Dick A, Chen M, Xu H
2014 Vision Translational Research Group symposium, Belfast, UK
Depletion of SOCS3 from myeloid cells worsens retinal inflammation and its associated
angiogenesis
Zhao J, Kissenpfennig A, Chen M, Xu H
2013 Infection & Immunity Translational Research Group symposium, Belfast, UK
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Reduced ocular inflammation in CCL2-/-CX3CR1gfp/gfp mice is neutrophil-dominated in
experimental autoimmune uveoretinitis
Zhao J, Chen M, Xu H
2012 International Society for Eye Research conference, Berlin, Germany
CCL2 and CX3CR1 Double Knockout Changes Macrophage Functionality
Zhao J, Chen M, Xu H
2011 European Macrophage and Dendritic Cell Society conference, Brussels, Belgium
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