Synthesis of some new pyrazole and pyrimidine derivatives carrying

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Curriculum Vitae
Professor Dr. Fatma Abdel-Fattah Ragab
Professor of Pharmaceutical Chemistry
Pharmaceutical Chemistry Department
Faculty of Pharmacy
Cairo University
Scientific
Faculty of Pharmacy-Cairo University
Qualifications
Academic

Ph.D. degree in Pharmaceutical Chemistry (1976)

M.Sc. Degree in Pharmaceutical Chemistry (1972)

B.Sc. in Pharmaceutical Sciences (1967)
Faculty of Pharmacy-Cairo University
Appointment

Head of Pharmaceutical Chemistry Department (2005-2007)

Professor of Pharmaceutical Chemistry (1993)

Assoc. Professor of Pharmaceutical Chemistry (1987)

Lecturer of Pharmaceutical Chemistry (1976)

Assistant Lecturer of Pharmaceutical Chemistry (1972)

Demonstrator of Pharmaceutical Chemistry (1967)
Research
Synthesis of new biologically active compounds and screening for
Field
their biological activities for use as drugs.
Recent
1. M.M. Ghorab, F.A. Ragab, E. Noaman, H.I.Heiba and E.M. El-
Publications
Hossary; Synthesis of some novel quinolines and pyrimido[4,5-
(2005-2008)
b]quinolines bearing sulfonamide moiety as potential
anticancer and radioprotective agents; Arzneimittel Forschung
Drug Res., 2007, 57 (12), 795-803.
2.
M.M. Ghorab, F.A. Ragab, E. Noaman, H.I.Heiba and E.M.
El-Hossary; Utility of 4-(5,5-dimethyl-3-oxo-cyclohex-1enylamino)benzene sulfonamide in synthesis of novel
quinolines as possible anticancer and radioprotective agents;
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Arzneimittel Forschung Drug Res., 2007, 57 (1), 35-41.
3.
M.M. Ghorab, E. Noaman, F.A. Ragab, H.I.Heiba and M.
Galal; Radioprotective and antitumor activity of some novel
amino acids, imidazoles containing thieno[2,3-d]pyrimidine
moiety; Phosphorus, Sulfur and Silicon, in press
4.
Fatma A. Ragab, Ghaneya S. Hassan, Hanan A. Yossef and
Hannan H. Hashem; Synthesis of 6- and 9alkylaminomethylfuroflavones as gastroprotective agents;
European J. of Medicinal Chemistry, 2007, 42, 1117-1127.
5. M. Y. Ebeid, M.M. Kamel, Z. M. Nofal, F.A. Ragab, W.A.
Zaghary and M El-Kady; Synthesis of some novel pyrido[3,2e]pyrrolo[1,2-c]pyrimidine derivatives of expected antiinflammatory activity; Egypt. J. Chem., 2007, 50(1), 105-116.
6. H.I.Heiba, F.A. Ragab, E. Noaman, M.M. Ghorab, and M.
Galal; Synthesis of some novel sulfur containing
triazolothienopyrimidine as possible antitumor and
radioprotective agents; Arzneimittel Forschung Drug Res.,
2006, 56 (8), 593-599.
7. M. Nabil Aboul-Einen, Aida El-Azzouny, Fatma Ragab, Wael
Soliman and Yousra Maklad; Synthesis and anticonvulsant
activity of ceratin N-aralkyl-N-(1-substituted
cyclohexyl)benzenamines, Sci. Pharm., 2006, 74, 1-19.
8. M.M. Ghorab, F.A. Ragab, E. Noaman, H.I.Heiba,and M.
Galal; Synthesis of certain new thieno[2,3-d]pyrimidines as
potential antitumor and radioprotective agents; Arzneimittel
Forschung Drug Res., 2006, 56 (7), 553-560.
9.
M. Y. Ebeid, M.M. Kamel, Z. M. Nofal, F.A. Ragab, W.A.
Zaghary and M El-Kady; New antimicrobial 9-(p-heterocyclosubstituted anilino)tetrahydroacridines; Egypt. J. Chem., 2006,
49(2), 277-285.
10. F.A. Ragab, M. M. Hanna, F. F. Barsoum, S.H. Fahim, M. Y.
Ebeid, and H. A. Salem; Synthesis and anti-inflammatory
activity of novel pyrimido[1,6-a]azonine and
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pyrimido[4',5':4,5]pyrimido [1,6-a]azonine derivatives; Egypt.
J. Chem., 2006, 49(2), 277-285.
11. Hassanein H. Hassaneien, Fatma A. Ragab, Enayat I. Aly and
Hanan H. Georgy; New fenamate analogs and
imidazoquinazolone derivatives: synthesis and antiinflammatory, analgesic and antipyretic activities; Alex. J.
Pharm. Sci., 2006, 20(2), 129.
12. F. A. Ragab, Hany, M. Safwat, Mohamed M. Hussein, Nagwa
M. Abd-El Gawad, Ghaneya S. Hassan and Sanaa A. Kenawy;
Synthesis and anticonvulsant activity of thiazzolidin-4-one
derivatives carrying a furochromone or benzofuran moiety;
Bull. Fac. Pharm. Cairo Univ., 2006, 44, 1103.
13. Fatma A. Ragab, Nahed M. Eid, Ghaneya S. Hassan and Yassin
M. Nissan; Synthesis and anticonvulsant activity of new 4thiazolidinones and 2-thioxo-4-imidazolidinones attached to 4oxo and thioxobenzopyranes; Bull. Fac. Pharm. Cairo Univ.,
2006, 44, 83-93.
14. F. A. Ragab, Enayat I. Aly, Nahed M. eid and Manal M.
Hussein; Synthesis and antimicrobial activity of novel 9anilinoacridines and 9-anilinomethylacridinium methylsulfates;
Alex. J. Pharm. Sci., 2005, 19(1).
15-Heba T. Abdel-Mohsen, Fatma A.F. Ragab, Mostafa M. Ramla,
Hoda I. El Diwani, “Novel benzimidazole–pyrimidine conjugates as
potent antitumor agents.”European Journal of Medicinal Chemistry, 2010; 45(6):
2336-44
16- Mostafa M. Ghorab, Fatma A. Ragab, Saleh I. Alqasoumi, Ahmed
M. Alafeefy, Sarah A. Aboulmagd. “Synthesis of some new pyrazolo[3,4d]pyrimidine derivatives of expected anticancer and radioprotective
activity.”European Journal of Medicinal Chemistry, 45 (2010) 171–178.
17- Ghorab MM, Ragab FA, Heiba HI, Youssef HA, Galal M.
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“Synthesis of some new pyrazole and pyrimidine derivatives
carrying a sulfonamide moiety of expected antitumor activity
and study of the synergistic effect of gamma irradiation.”
Arzneimittelforschung, 2010; 60(1):48-55.
18-Synthesis and docking studies of some novel quinoline derivatives
bearing a sulfonamide moiety as possible anticancer agents.
Arzneimittelforschung 2010, 60,(3) 141-148
19-Synthesis and anticonvulsant activity of 4-oxo and 4-thioxo-8bromobenzopyran derivatives.
Arzneimittelforschung 2010, 60(4) 171-176.
20-Synthesis and anticonvulsant activity of certain substituted
furochromone, benzofuran, and flavone derivatives.
Chem Pharm Bull 5899) 1148-1156 (2010)
21-Mostafa M. Ghorab, Fatma A..Ragab, Helmy I.Heiba, ReemK.Arafa,
Ebaa M, El-Hossary.
In vitro anticancer screening and radiosessitizing evaluation of some new
quinolines and pyrimido_(4,5-b) quinolines bearing a sulfonamide moiety
European Journal of Medicinal Chemistry 45 (20100 3677-3684
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