Scientific Programme Programme, Thursday, 16 October 2008 19.00 – 19.30 Opening and welcome Z. Culig, Innsbruck (AT) N. Maitland, York (GB) N. Malats, Madrid (ES) J. Reventós, Barcelona (ES) 19.30 – 20.00 Keynote lecture From inception to trade sale: The entrepreneur's perspective J. Jean-Mairet, Barcelona (ES) 18th Meeting of the European Society for Urological Research (ESUR) Programme, Friday, 17 October 2008 07.30 – 09.00 Training course Basic molecular biology for urologists Coordinator: M. Abal, Barcelona (ES) Molecular pathology J. Castellvi, Barcelona (ES) Proteomics D. Andreu, Barcelona (ES) Gene expression F. Núñez, Barcelona (ES) Stem cells M. Santos, Lisbon (PT) Cytomics J. Pétriz, Barcelona (ES) Animal models A. Doll, Barcelona (ES) 08.45 – 09.00 Welcome refreshments 09.00 – 11.30 Survival and metastatis in urological cancers Chairs: C. Bangma, Rotterdam (NL) Z. Culig, Innsbruck (AT) 09.00 – 09.30 Cell signaling in prostate cancer metastasis L. Languino, Worcester (US) 09.30 – 10.00 Mechanisms of progression in bladder cancer F. Real, Madrid (ES) 10.00 – 10.30 Calcium signatures of prostate cancer N. Prevarskaya, Lille (FR) 10.30 – 11.00 Refreshment break 11.00 – 11.30 Mechanisms of osteoblast activation in prostate cancer bone metastasis M. Cecchini, Berne (CH) 11.30 – 12.30 Oral session 1 Selected oral presentations: abstract numbers 1-4 12.30 – 13.30 Poster guided tour Chairs: L. Languino, Worcester (US) M. Cecchini, Berne (CH) N. Prevarskaya, Lille (FR) 13.30 – 15.00 Lunch and poster session 1 Selected poster presentations: abstract numbers 5-44 4 18th Meeting of the European Society for Urological Research (ESUR) 15.00 – 17.00 Genetic susceptibility and urological disorders Chairs: A. Bjartell, Malmö (SE) J. Palou Redorta, Barcelona (ES) 15.00 – 15.30 Familiality of risk and survival in kidney cancer K. Hemminki, Heidelberg (DE) 15.30 – 16.00 Genetic susceptibility to testicular cancer E. Rajpert-De Meyts, Copenhagen (DK) 16.00 – 16.30 Bladder cancer genetic susceptibility N. Rothman, Rockville (US) 16.30 – 17.00 Somatic genetic alterations in prostate cancer T. Visakorpi, Tampere (FI) 17.00 – 17.30 Refreshment break 17.30 – 18.30 Oral session 2 Selected oral presentations: abstract numbers 45-48 18.30 – 19.30 Special session International networking in urological research Chairs: N. Malats, Madrid (ES) M. Cecchini, Berne (CH) Panelists: N. Maitland, York (GB) M. Bussemakers, Nijmegen (NL) B. Schmidt-Drager, Fürth (DE) T. Visakorpi, Tampere (FI) 5 18th Meeting of the European Society for Urological Research (ESUR) Programme, Saturday, 18 October 2008 07.30 – 09.00 Training course Pharmacogenomics for urologists Coordinator: A. Gonzalez-Neira, Madrid (ES) Human genome variation and pharmacogenetics: general concepts and analysis tools A. González Neira, Madrid (ES) Bioinformatics for pharmacogenomics: a quick overview A. Navarro, Barcelona (ES) Association studies: design, analysis and interpretation of results R. Milne, Madrid (ES) Recent findings on pharmacogenomic prediction of platinum sensitivity in bladder cancer J. Bellmunt, Barcelona (ES) 08.45 – 09.00 Welcome refreshments 09.00 – 11.30 Hormones in urological disease Chairs: G. Jenster, Rotterdam (NL) T. Visakorpi, Tampere (FI) 09.00 – 09.30 The key role of the androgen receptor in prostate cancer J. Trapman, Rotterdam (NL) 09.30 – 10.00 Cell-selective knockouts of the androgen receptor: A novel tool in the study of androgen action G. Verhoeven, Leuven (BE) 10.00 – 10.30 Wnt and Wnt antagonist signaling in prostate cancer R. Kypta, Bilbao (ES) and London (GB) 10.30 – 11.00 Refreshment break 11.00 – 11.30 Advances in the management of castration resistant prostate cancer D. Olmos, Sutton (GB) 11.30 – 12.30 Oral session 3 Selected oral presentations: abstract numbers 49-52 12.30 – 13.30 Poster guided tour Chairs: J. Trapman, Rotterdam (NL) G. Verhoeven, Leuven (BE) D. Olmos, Sutton (GB) 13.30 – 15.00 Lunch and poster session 2 Selected poster presentations: abstract numbers 53-89 6 18th Meeting of the European Society for Urological Research (ESUR) 15.00 – 17.50 Scientific basis for clinical trials Chairs: M. Mancini, Padova (IT) 15.00 – 15.30 Implementation of basic research in clinical trials for bladder and prostate cancer C. Bangma, Rotterdam (NL) 15.30 – 16.00 Predicting therapeutic response in bladder cancer: Do we have biomarkers available? M. Sanchez-Carbayo Martin, Madrid (ES) 16.00 – 16.30 Anti-angiogenic drugs in adjuvant and neoadjuvant settings in renal cell carcinoma J-J. Patard, Rennes (FR) 16.30 – 17.00 Molecular pathways linking inflammation and cancer P. Allavena, Milan (IT) 17.00 – 17.30 Refreshment break 17.30 – 19.00 Special session Turning science into value: Urological research as a driver of the new economy Chairs: F. Jankevicius, Vilnius (LT) J. Reventos, Barcelona (ES) Panelists: M. Vendrell, Barcelona (ES) J. Merino, Barcelona (ES) L. Pareras, Barcelona (ES) L. Ruiz, Barcelona (ES) J. Sanfeliu, Barcelona (ES) 7