Professor Richard Beale’s publications
1.
Physiological predictors of survival during high-frequency oscillatory ventilation in adults with
acute respiratory distress syndrome. Camporota L, Sherry T, Smith J, Lei K, McLuckie A, Beale R. Crit
Care. 2013 Mar 4;17(2):R40.
2.
Retrospective analysis of outcome of women with breast or gynaecological cancer in the
intensive care unit. Ostermann M, Raimundo M, Williams A, Whiteley C, Beale R. JRSM Short Rep. 2013
Jan;4(1):2.
3.
Surviving sepsis campaign: international guidelines for management of severe sepsis and
septic shock: 2012. Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE,
Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM,
Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb SA, Beale RJ, Vincent JL, Moreno R;
Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup. Crit Care Med.
2013;41:580-637.
4.
Acute Respiratory Distress Syndrome; The Berlin Definition. The ARDS Definition Task Force.
JAMA 2013;307: 2526-33
5.
Reinhart K, Perner A, Sprung CL, Jaeschke R, Schortgen F, Johan Groeneveld AB, Beale R, Hartog
CS. Consensus statement of the ESICM task force on colloid volume therapy in critically ill patients.
Intensive Care Med. 2012;38(3):368-83.
6.
Global utilization of low-dose corticosteroids in severe sepsis and septic shock: a report from
the PROGRESS registry. Beale R, Janes JM, Brunkhorst FM, Dobb G, Levy MM, Martin GS, Ramsay G,
Silva E, Sprung CL, Vallet B, Vincent JL, Costigan TM, Leishman AG, Williams MD, Reinhart K. Crit Care.
2010 Jun 3;14(3):R102.
7.
The Surviving Sepsis Campaign: results of an international guideline-based performance
improvement program targeting severe sepsis. Levy MM, Dellinger RP, Townsend SR, Linde-Zwirble
WT, Marshall JC, Bion J, Schorr C, Artigas A, Ramsay G, Beale R, Parker MM, Gerlach H, Reinhart K, Silva
E, Harvey M, Regan S, Angus DC; Surviving Sepsis Campaign. Crit Care Med. 2010 Feb;38(2):367-74.
8.
Kesecioglu J, Beale R, Stewart TE, Findlay GP, Rouby JJ, Holzapfel L, Bruins P, Steenken EJ,
Jeppesen OK, Lachmann B. Exogenous Natural Surfactant for Treatment of Acute Lung Injury and the
Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2009 Aug 27. [Epub ahead of print]
9.
Beale R, Reinhart K, Brunkhorst FM, Dobb G, Levy M, Martin G, Martin C, Ramsey G, Silva E,
Vallet B, Vincent JL, Janes JM, Sarwat S, Williams MD; PROGRESS Advisory Board. Promoting Global
Research Excellence in Severe Sepsis (PROGRESS): lessons from an international sepsis registry.
Infection. 2009 Jun;37(3):222-32. Epub 2009 Apr 28.
1 of 6
10.
Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, BrunBuisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M,
Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL;
International Surviving Sepsis Campaign Guidelines Committee; American Association of Critical-Care
Nurses; American College of Chest Physicians; American College of Emergency Physicians; Canadian
Critical Care Society; European Society of Clinical Microbiology and Infectious Diseases; European
Society of Intensive Care Medicine; European Respiratory Society; International Sepsis Forum;
Japanese Association for Acute Medicine; Japanese Society of Intensive Care Medicine; Society of
Critical Care Medicine; Society of Hospital Medicine; Surgical Infection Society; World Federation of
Societies of Intensive and Critical Care Medicine. Surviving Sepsis Campaign: international guidelines
for management of severe sepsis and septic shock: 2008. Crit Care Med. 2008 Jan;36(1):296-327
11.
Beale RJ, Sherry T, Lei K, Campbell-Stephen L, McCook J, Smith J, Venetz W, Alteheld B, Stehle P,
Schneider H. Early enteral supplementation with key pharmaconutrients improves Sequential Organ
Failure Assessment score in critically ill patients with sepsis: outcome of a randomized, controlled,
double-blind trial. Crit Care Med. 2008 Jan;36(1):131-44.
12.
Vincent JL, Bernard GR, Beale R, Doig C, Putensen C, Dhainaut JF, Artigas A, Fumagalli R, Macias
W, Wright T, Wong K, Sundin DP, Turlo MA, Janes J. Drotrecogin alfa (activated) treatment in severe
sepsis from the global open-label trial ENHANCE: further evidence for survival and safety and
implications for early treatment. Crit Care Med. 2005 Oct;33(10):2266-77.
13.
The Surviving Sepsis Campaign: results of an international guideline-based performance
improvement program targeting severe sepsis. Levy MM, Dellinger RP, Townsend SR, Linde-Zwirble
WT, Marshall JC, Bion J, Schorr C, Artigas A, Ramsay G, Beale R, Parker MM, Gerlach H, Reinhart K, Silva
E, Harvey M, Regan S, Angus DC. Intensive Care Med. 2010 Feb;36(2):222-31. Epub 2010 Jan 13.
14.
The Surviving Sepsis Campaign: results of an international guideline-based performance
improvement program targeting severe sepsis. Levy MM, Dellinger RP, Townsend SR, Linde-Zwirble
WT, Marshall JC, Bion J, Schorr C, Artigas A, Ramsay G, Beale R, Parker MM, Gerlach H, Reinhart K, Silva
E, Harvey M, Regan S, Angus DC; Surviving Sepsis Campaign. Crit Care Med. 2010 Feb;38(2):367-74.
15.
The Metabolic Effects of Intensive Insulin Therapy in Critically Ill Patients. Whyte M, Jackson N,
Shojaee-Moradie F, Treacher D, Beale R, Jones R, Umpleby M. Am J Physiol Endocrinol Metab. 2009
Dec 22. [Epub ahead of print]
16.
Kesecioglu J, Beale R, Stewart TE, Findlay GP, Rouby JJ, Holzapfel L, Bruins P, Steenken EJ,
Jeppesen OK, Lachmann B. Exogenous Natural Surfactant for Treatment of Acute Lung Injury and the
Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2009 Aug 27
17.
Beale RJ, Reinhart K, Brunkhorst FM, Dobb G, Levy M, Martin G, Martin C, Ramsey G, Silva E,
Vallet B, Vincent J-L, Janes JM, Sarwat S, Williams MD. Promoting Global Research Excellence in Severe
Sepsis (PROGRESS): Lessons from an International Sepsis Registry. Infection A journal of Infectious
Disease June 2009; 37 (3) 222-232
2 of 6
18.
Martin G, Brunkhorst FM, Janes JM, Reinhart K, Sundin DP, Garnett K, Beale R. The
international PROGRESS registry of patients with severe sepsis: drotrecogin alfa (activated) use and
patient outcomes. Crit Care. 2009;13(3):R103. Epub 2009 Jun 30
19.
Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, BrunBuisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M,
Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL;
International Surviving Sepsis Campaign Guidelines Committee; American Association of Critical-Care
Nurses; American College of Chest Physicians; American College of Emergency Physicians; Canadian
Critical Care Society; European Society of Clinical Microbiology and Infectious Diseases; European
Society of Intensive Care Medicine; European Respiratory Society; International Sepsis Forum;
Japanese Association for Acute Medicine; Japanese Society of Intensive Care Medicine; Society of
Critical Care Medicine; Society of Hospital Medicine; Surgical Infection Society; World Federation of
Societies of Intensive and Critical Care Medicine. Surviving Sepsis Campaign: international guidelines
for management of severe sepsis and septic shock: 2008. Crit Care Med. 2008 Jan;36(1):296-327.
Erratum in: Crit Care Med. 2008 Apr;36(4):1394-6.
20.
Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, BrunBuisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M,
Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL. Surviving
Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008.
Intensive Care Med. 2008 Jan;34(1):17-60.
21.
Beale RJ, Sherry T, Lei K, Campbell-Stephen L, McCook J, Smith J,Venetz W, Alteheld B, Stehle P,
Schneider H. Early enteral supplementation with key pharmaconutrients improves Sequential Organ
Failure Assessment score in critically ill patients with sepsis: outcome of a randomized, Controlled,
double-blind trial. Crit Care Med.2008 Jan;36(1):131-44.
22.
Camporota L, Corno E, Menaldo E, Smith J, Lei K, Beale R, Wyncoll D. Filter survival time and
requirement of blood products in patients with severe sepsis receiving drotrecogin alfa (activated)
and requiring renal replacement therapy. Crit Care. 2008;12(6):R163. Epub 2008 Dec 18
23.
Edgeworth JD, Yadegarfar G, Pathak S, Batra R, Cockfield JD, Wyncoll D, Beale R, Lindsay JA. An
outbreak in an intensive care unit of a strain of methicillin-resistant Staphylococcus aureus sequence
type 239 associated with an increased rate of vascular access device-related bacteremia. Clin Infect
Dis. 2007 Feb 15;44(4):493-501.
24.
Z'Graggen WJ, Lin CS, Howard RS, Beale RJ, Bostock H. Nerve excitability changes in critical
illness polyneuropathy. Brain. 2006 Sep;129(Pt 9):2461-70.
25.
Jones A, Webb I, Gibbs T, Beale R. Discordant response to ACTH
with septic shock. Intensive Care Med. 2006 Sep;32(9):1440-1.
stimulation in patients
26.
O'Callaghan G, Beale RJ. The role of immune-enhancing diets in the management of
perioperative patients. Crit Care Resusc. 2003 Dec;5(4):277-83.
3 of 6
27.
Vincent JL, Bernard GR, Beale R, Doig C, Putensen C, Dhainaut JF, Artigas A, Fumagalli R, Macias
W, Wright T, Wong K, Sundin DP, Turlo MA, Janes J. Drotrecogin alfa (activated) treatment in severe
sepsis from the global open-label trial ENHANCE: further evidence for survival and safety and
implications for early treatment. Crit Care Med. 2005 Oct;33(10):2266-77.
28.
Bollen CW, van Well GT, Sherry T, Beale RJ, Shah S, Findlay G, Monchi M, Chiche JD, Weiler N,
Uiterwaal CS, van Vught AJ. High frequency oscillatory ventilation compared with conventional
mechanical ventilation in adult respiratory distress syndrome: a randomized controlled trial
Crit Care. 2005 Aug;9(4):R430-9.
29.
Nathens AB, Curtis JR, Beale RJ, Cook DJ, Moreno RP, Romand JA, Skerrett SJ, Stapleton RD,
Ware LB, Waldmann CS. Management of the critically ill patient with severe acute pancreatitis. Crit
Care Med. 2004 Dec;32(12):2524-36.
30.
Beale RJ, Hollenberg SM, Vincent JL, Parrillo JE. Vasopressor and inotropic support in septic
shock: an evidence-based review. Crit Care Med. 2004 Nov;32(11 Suppl):S455-65.
31.
Reinhart K, Meier-Hellmann A, Beale R, Forst H, Boehm D, Willatts S, Rothe KF, Adolph M,
Hoffmann JE, Boehme M, Bredle DL; EASy-Study Group. Open randomized phase II trial of an
extracorporeal endotoxin adsorber in suspected Gram-negative sepsis. Crit Care Med.
2004Aug;32(8):1662-8.
32.
Abraham E, Reinhart K, Opal S, Demeyer I, Doig C, Rodriguez AL, Beale R, Svoboda P, Laterre PF,
Simon S, Light B, Spapen H, Stone J, Seibert A, Peckelsen C, De Deyne C, Postier R, Pettila V, Artigas A,
Percell SR, Shu V, Zwingelstein C, Tobias J, Poole L, Stolzenbach JC,
Creasey AA; OPTIMIST
Trial Study Group. Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in
severe sepsis: a randomized controlled trial.JAMA.2003Jul9;290(2):238-47.
33.
Dargan PI, Giles LJ, Wallace CI, House IM, Thomson AH, Beale RJ, Jones AL. Case report: severe
mercuric sulphate poisoning treated with 2,3-dimercaptopropane-1-sulphonate and
haemodiafiltration. Crit Care. 2003 Jun;7(3):R1-6.
34.
Honore PM, Jacquet LM, Beale RJ, Renauld JC, Valadi D, Noirhomme P, Goenen M. Effects of
normothermia versus hypothermia on extravascular lung water and serum cytokines during
cardiopulmonary bypass: a randomized, controlled trial. Crit Care Med. 2001 ct;29(10):1903-9.
35.
Daly K, Beale R, Chang RW. Reduction in mortality after inappropriate early discharge from
intensive care unit: logistic regression triage model.BMJ.2001.May26;322(7297):1274-6.
36.
Wyncoll D, Beale R. Immunologically enhanced enteral nutrition: current status. Curr Opin Crit
Care. 2001 Apr;7(2):128-32.
37.
Giles LJ, Jennings AC, Thomson AH, Creed G, Beale RJ, McLuckie A. Pharmacokinetics of
meropenem in intensive care unit patients receiving continuous veno-venous hemofiltration or
hemodiafiltration. CritCareMed.2000Mar;28(3):632-7.
4 of 6
38.
Boyle NH, Roberts PC, Ng B, Berkenstadt H, McLuckie A, Beale RJ, Mason RC. Scanning laser
Doppler is a useful technique to assess foot cutaneous perfusion during femoral artery cannulation.
Crit Care. 1999;3(4):95-100.
39.
Jacquet L, Honore P, Beale R, Valadi D, Dion R, Goenen M. Cardiac function after intermittent
antegrade warm blood cardioplegia:
contribution of the double-indicator dilution technique.
Intensive Care Med.2000Jun;26(6):686-92.
40.
Sakka SG, Ruhl CC, Pfeiffer UJ, Beale R, McLuckie A, Reinhart K, Meier-Hellmann A. Assessment
of cardiac preload and extravascular lung water by single transpulmonary thermodilution. Intensive
Care Med.2000Feb;26(2):180-7.
41.
Beale RJ, Bryg DJ, Bihari DJ. Immunonutrition in the critically ill: a systematic review of clinical
outcome. Crit Care Med. 1999 Dec;27(12):2799-805.
42.
Sandison AJ, Wyncoll DL, Edmondson RC, Van Heerden N, Beale RJ, Taylor PR. ICU protocol may
affect the outcome of non-elective abdominal aortic aneurysm repair. Eur J Vasc Endovasc Surg. 1998
Oct;16(4):356-61.
43.
Newman PJ, Quinn AC, Grounds RM, Hunter JM, Boyd AH, Eastwood NB, Pollard BJ, Pearson
AJ, Harper NJ, Beale RJ, Sutjarittam M, Elliot JM, Bion JF. A comparison of cisatracurium (51W89) and
atracurium by infusion in critically ill patients. Crit Care Med. 1997 Jul;25(7):1139-42.
44.
Wyncoll DL, Roberts PC, Beale RJ, McLuckie A.H2 blockers in the intensive care unit: ignoring
the evidence? Telephone survey. BMJ. 1997 Apr 5;314(7086):1013.
45.
Maynard ND, Bihari DJ, Dalton RN, Beale R, Smithies MN, Mason RC.Liver function and
splanchnic ischemia in critically ill patients. Chest. 1997Jan;111(1):180-7.
46.
Lichtwarck-Aschoff M, Beale R, Pfeiffer UJ.Central venous pressure, pulmonary artery occlusion
pressure, intrathoracic blood volume, and
right ventricular end-diastolic volume as indicators
of cardiac preload. J CritCare.1996Dec;11(4):180-8.
47.
Beale R. VO2 and DO2 during cardiogenic shock and infection. Anasthesiol Intensivmed
Notfallmed Schmerzther. 1996 May;31(1 Suppl):S22-5. Review.
48.
Stuart LM, Rice PS, Lloyd G, Beale RJ. A soldier in respiratory distress. Lancet. 1996 Jan
6;347(8993):30.
49.
Grover ER, Beale R, Smithies M, Bihari D. Nitric oxide and ARDS.
Anaesth Intensive Care. 1994 Jun;22(3):312-3.
50.
Smithies M, Yee TH, Jackson L, Beale R, Bihari D. Protecting the gut and the liver in the critically
ill: effects of dopexamine. Crit Care Med. 1994May;22(5):789-95.
5 of 6
51.
Beale R, Grover ER, Smithies M, Bihari D. Acute respiratory distress syndrome ("ARDS"): no
more than a severe acute lung injury? BMJ. 1993 Nov 20;307(6915):1335-9.
52.
Maynard N, Bihari D, Beale R, Smithies M, Baldock G, Mason R, McCollI.Assessment of
splanchnic oxygenation by gastric tonometry in patients with acute circulatory failure. JAMA. 1993
Sep 8;270(10):1203-10.
53.
Fairfield JE, Dritsas A, Beale RJ. Haemodynamic effects of propofol: induction with 2.5 mg kg-1.
Br J Anaesth. 1991 Nov;67(5):618-20.
Editorials
1.
Gardner RM, Beale RJ Pressure to perform: is cardiac output estimation from arterial
waveforms good enough for routine use? Crit Care Med. 2009 Jan;37(1):337-8.
2.
Beale R. Echoes of the past? Crit Care Med. 2008 Jun;36(6):1950-1.
3.
Beale R. Are we ready for MEDS in the ED? Crit Care Med. 2007 Jan;35(1):318-9.
Multiple organ failure: the pilgrim's progress. Beale R, Bihari D. Crit Care Med. 1993 Feb;21(2
Suppl):S1-3.
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