HIV <3> Database EMBASE Accession Number 2009290848 Authors Bao Y.-P. Liu Z.-M. Institution (Bao, Liu) National Institute on Drug Dependence, Peking University, 38 Xue Yuan Road, Hai Dian District, Beijing 100191, China. Country of Publication United Kingdom Title Current situation and trends of drug abuse and HIV/AIDS in China. Source Future HIV Therapy. 3(3)(pp 237-240), 2009. Date of Publication: 2009. Publisher Future Medicine Ltd. Abstract Drug abuse re-emerged in mainland China in the 1980s and has spread dramatically over the last decades; the cumulative number of registered drug users increased to 1.16 million by the end of 2005. Among them, 78.3% were heroin addicts and the majority of them (50-70%) were injecting drug users. The abuse of amphetamine-type stimulants emerged at the end of the 1990s and spread quickly. Injecting drug use and unsafe sexual behavior among drug users have been the key factors in the spread of HIV/AIDS. By the end of September 2008, the cumulative total of reported HIV/AIDS cases was 264,302 in China. The Chinese government takes great measures and strategies to prevent HIV/AIDS transmission and reduce drug-related harms, including methadone-maintenance treatment and needleexchange programs. Moreover, antiretroviral therapy has been provided for AIDS patients. The Chinese government will continue to implement strategies to prevent the spread of HIV/AIDS among drug users in the future. copyright 2009 Future Medicine Ltd. ISSN 1746-9600 Publication Type Journal: Article Journal Name Future HIV Therapy Volume 3 Issue Part 3 Page 237-240 Year of Publication 2009 Date of Publication 2009 HIV <11> Database EMBASE Accession Number 2009228890 Authors Marshall B.D.L. Wood E. Zhang R. Tyndall M.W. Montaner J.S.G. Kerr T. Institution (Marshall, Wood, Zhang, Tyndall, Montaner, Kerr) British Columbia Centre for Excellence, HIV/AIDS, St. Paul's Hospital, Vancouver, BC, Canada. (Marshall) School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada. (Wood, Tyndall, Montaner, Kerr) Department of Medicine, University of British Columbia, St. Paul's Hospital, Vancouver, BC, Canada. (Kerr) British Columbia Centre for Excellence, HIV/AIDS, St. Paul's Hospital, 608-1081 Burrard Street, Vancouver, BC V6Z 1Y6, Canada. Country of Publication United Kingdom Title Condom use among injection drug users accessing a supervised injecting facility. Source Sexually Transmitted Infections. 85(2)(pp 121-126), 2009. Date of Publication: 01 Apr 2009. Publisher BMJ Publishing Group Abstract Objectives: Although supervised injecting facility (SIF) use has been associated with reductions in injection-related risk behaviours, the impact of SIFs on the sexual behaviour of injection drug users (IDUs) has not been thoroughly investigated. Therefore, we examined the patterns and predictors of condom use among SIF users in Vancouver, Canada. Methods: We performed a longitudinal analysis of the factors associated with consistent condom use among IDUs recruited from within a SIF. Results: Among 1090 individuals, 650 (59.6%) reported a sexual partner in the past 6 months at baseline. Consistent condom use was reported by 108 (25.3%) and 205 (61.6%) individuals reporting regular or casual partners, respectively. After 2 years of observation, these proportions increased to 32.9% and 69.8%, respectively. In multivariate analysis, predictors of consistent condom use with regular partners included HIV positivity (adjusted odds ratio (AOR) 2.23; 95% CI 1.51 to 3.31), injecting with a sex partner (AOR 0.50; 95% CI 0.37 to 0.68), enrollment in addiction treatment (AOR 0.68, 95% CI 0.52 to 0.89) and time since recruitment (AOR 1.29; 95% CI 1.06 to 1.55 per year). Predictors of consistent condom use with casual partners included HIV positivity (AOR 1.70; 95% CI 1.03 to 2.81), syringe borrowing (AOR 0.54; 95% CI 0.32 to 0.91) and syringe lending (AOR 0.52; 95% CI 0.32 to 0.84). Conclusions: Our results demonstrate that among SIF users, consistent condom use was more frequent among casual sex partners and among HIV positive individuals. Importantly, while the prevalence of consistent condom use was low at baseline, it increased over time. Our findings suggest a possible beneficial effect of the SIF on safer sexual practices. ISSN 1368-4973 Publication Type Journal: Article Journal Name Sexually Transmitted Infections Volume 85 Issue Part 2 Page 121-126 Year of Publication 2009 Date of Publication 01 Apr 2009 HIV <114> Database EMBASE Accession Number 2009150940 Authors Nijhawan A. Kim S. Rich J.D. Institution (Rich) Brown Medical School, The Miriam Hospital, 164 Summit Avenue, Providence, RI 02906, United States. Country of Publication United Kingdom Title Management of HIV infection in patients with substance use problems. Source Current Infectious Disease Reports. 10(5)(pp 432-438), 2008. Date of Publication: 2008. Publisher Current Science Ltd Abstract Although highly active antiretroviral therapy (HAART) has greatly reduced overall morbidity and mortality in patients with HIV, patients with substance use issues have been less likely than other patients with HIV to realize these benefits. Social obstacles (eg, lack of housing, minimal social support), and medical comorbidities (eg, mental illness, hepatitis), complicate the management of this group of patients. Not only are drug and alcohol users less likely to access medical care, initiation of HAART may be delayed due to concerns for adherence and the potential development of drug resistance. Ultimately, a multidisciplinary comprehensive approach is needed to both engage and retain this population in care. Through the integration of case management, addiction therapy, and medical treatment of HIV, we may be able to improve out-comes for patients with HIV and addiction. copyright Current Medicine Group LLC 2008. ISSN 1523-3847 Publication Type Journal: Review Journal Name Current Infectious Disease Reports Volume 10 Issue Part 5 Page 432-438 Year of Publication 2008 Date of Publication 2008 HIV <119> Database EMBASE Accession Number 2009131690 Authors Vlassova N. Angelino A.F. Treisman G.J. Institution (Vlassova, Angelino, Treisman) 600 North Wolfe Street, Baltimore, MD 21287, United States. Country of Publication United Kingdom Title Update on mental health issues in patients with HIV infection. Source Current Infectious Disease Reports. 11(2)(pp 163-169), 2009. Date of Publication: 2009. Publisher Current Science Ltd Abstract HIV infection remains a major world health problem more than 20 years after discovery of the virus. Mental disorders make individuals more vulnerable to behaviors that transmit HIV and interfere with HIV treatment adherence. The evidence supporting the need for optimal provision of mental health care in HIV clinics is mounting, along with evidence that these disorders can be treated successfully. Disorders of mental life include brain diseases (eg, depression, bipolar disorder, schizophrenia, and dementia), personality disorders, addictions, and psychologic disruptions, which contribute to the spread of the virus through their influence on behavior. However, although evidence exists that successful treatment of co-occurring mental disorders leads to improved HIV outcomes, integrated mental health care in HIV clinics remains grossly suboptimal. copyright Current Medicine Group, LLC 2009. ISSN 1523-3847 Publication Type Journal: Review Journal Name Current Infectious Disease Reports Volume 11 Issue Part 2 Page 163-169 Year of Publication 2009 Date of Publication 2009 VIROLOGY <130> Database EMBASE Accession Number 2009121274 Authors Alavi S.M. Alavi L. Institution (Alavi, Alavi) Infectious Diseases and Tropical Medicine Research Center, Jundishapoor University of Medical Sciences, Ahvaz, Iran, Islamic Republic of. Country of Publication United Kingdom Title Seroprevalence study of HCV among hospitalized intravenous drug users in Ahvaz, Iran (2001-2006). Source Journal of Infection and Public Health. 2(1)(pp 47-51), 2009. Date of Publication: 2009. Publisher Elsevier Ltd Abstract Background and aims: Prevalence of hepatitis C virus (HCV) in intravenous drug users (IDU) varies in different areas according to socioeconomic and geographical circumstances. The present study was performed to determine seroprevalence of HCV in IDU individuals in Ahvaz, Iran. Materials and methods: 142 IDU patients were included in this retrospective study in Ahvaz southwest Iran from 2001 to 2006. Patients were placed in two groups determined by HCV Ab positive or negative status. Data were analyzed using SPSS for Windows (version 11.5; SPSS Inc., USA) software. Results: Out of total 142 cases, 74 persons (52.11%) had a positive HCV-Ab test according to the ELISA method. There was no difference in age, sex, level of education, residency and co-infection with HIV and hepatitis B virus between HCV-Ab positive (HAP) and HCV-Ab negative (HAN) groups (p > 0.05). HCVAb positivity was significantly related to imprisonment and duration spent in prison [OR: 3.22, 95% (CI) 2.61-3.76, p < 0.0001]. Conclusion: Patients with IDU constitute a high-risk group for acquisition of HCV infection. Transmission of HCV via sharing syringe and needle as well as blood transfusion has been a significant source of hepatitis C infection for patients with intravenous drug addiction. copyright 2009 King Saud Bin Abdulaziz University for Health Sciences. ISSN 1876-0341 Publication Type Journal: Article Journal Name Journal of Infection and Public Health Volume 2 Issue Part 1 Page 47-51 Year of Publication 2009 Date of Publication 2009