Chapter 24 CHAPTER 24 – NUTRITION AND LOWER GASTROINTESTINAL DISORDERS CHAPTER SUMMARY Common lower gastrointestinal symptoms and complications with nutrition implications include constipation, intestinal gas, diarrhea, bacterial overgrowth and steatorrhea. Causes of constipation include low fiber intake, physical inactivity and overall low food intake; all of which can be reversed to treat the condition, and various systemic disorders, neurological conditions, psychological problems and side effects of several classes of medications. Although many individuals may self-diagnose themselves as having intestinal gas, it may actually be dyspepsia or irritable bowel syndrome. Diarrhea can have many causes and may be acute or chronic. Treatment of diarrhea is essential to prevent dehydration and electrolyte imbalances. Bacterial overgrowth can be caused by gastric surgery, conditions that slow intestinal motility, and reduced gastric acid secretion. Treatment includes antibiotics, cessation of acidreducing therapies, use of medium-chain-triglycerides (MCT) and dietary supplements. Steatorrhea, fat maldigestion or malabsorption, can be caused by pancreatitis, cystic fibrosis, Crohn’s disease, and celiac disease. Consequences of fat malabsorption include weight loss and malnutrition, essential fatty acid deficiency, increased risk of bone loss and increased risk of oxalate stone formation. Treatment for steatorrhea may include a fat-restricted diet and the incorporation of MCT oil. Malabsorption syndromes can have significant nutrition consequences. Common malabsorption syndromes include pancreatitis, cystic fibrosis, celiac disease, inflammatory bowel disease and short bowel syndrome. Pancreatitis, inflammation of the pancreas, can be acute or chronic, with excessive alcohol consumption being the primary cause for both conditions. Chronic pancreatitis can cause irreversible damage to pancreatic tissue. Medical nutrition therapy for acute pancreatitis includes a gradual progression from NPO status to solid foods in small, frequent feedings, typically starting with a low-fat diet. Medical nutrition therapy for chronic pancreatitis includes abstinence from alcohol, dietary supplements, pancreatic enzyme replacement and a low-fat diet as needed. Cystic fibrosis, an inherited mutation in the gene for a membrane protein that transports chloride ions, can result in serious complications involving the lungs and pancreas. Medical nutrition therapy for cystic fibrosis includes high energy intake, vitamin and mineral supplements, pancreatic enzyme replacement therapy, liquid dietary supplements, and often supplemental tube feedings. Celiac disease, an abnormal response to a protein fraction in wheat gluten, gliadin, involves treatment with a lifelong gluten-free diet, eliminating all foods that contain wheat, rye, barley and possibly oats. Inflammatory bowel disease, including Crohn’s disease and ulcerative colitis, involves careful nutrition planning to replace lost nutrients and correct nutrient deficiencies. Short bowel syndrome, the malabsorption syndrome that results when the absorptive capacity of the remaining intestine is insufficient for meeting nutritional needs, can be helped by intestinal adaptation. Medical nutrition therapy for short bowel syndrome includes appropriate rehydration, gradual progression of oral feedings and total parenteral nutrition after surgery. Dietary recommendations include low lactose intake, fluids between meals, emphasis on complex carbohydrates, low oxalate intake and vitamin and mineral supplementation. Conditions affecting the large intestine with nutrition implications include irritable bowel syndrome, diverticular disease of the colon and ostomies. Irritable bowel syndrome includes chronic and recurring intestinal symptoms that cannot be explained by specific physical abnormalities, but stress and anxiety are among the contributing factors. Dietary treatment includes a high-fiber diet and avoidance of lactose in lactose-intolerant individuals. High-fiber diets are also beneficial for the treatment of diverticulosis, the presence of small pouches (diverticula) in the intestinal wall. Treatment for medical conditions that affect the large intestine sometimes requires surgical removal of some or all of the large intestine. Patients with 361 Chapter 24 ostomies, including colostomies and ileostomies, may experience diarrhea, excessive fluid loss and obstructions. Dietary intervention includes chewing thoroughly, adequate fluid intake and avoiding foods that may cause excessive gas production. Highlight 24 reviews food allergy diagnosis and dietary concerns. 362