Title: Elevated Reports of Anxiety Symptoms among Pediatric Chronic Pain Patients: A Need for Routine Screening? Authors: Susan T. Heinze, BA, University of Wisconsin-Milwaukee Kim Anderson Khan, PsyD, Medical College of Wisconsin, Children’s Hospital of Wisconsin Keri R. Hainsworth, PhD, Medical College of Wisconsin Steven J. Weisman, MD, Medical College of Wisconsin, Children’s Hospital of Wisconsin Corresponding Author: Susan T. Heinze, Department of Psychology, University of Wisconsin-Milwaukee 2441 E. Hartford Ave, Milwaukee, WI 53211 stheinze@uwm.edu Purpose/Background: Children with chronic pain report more symptoms of anxiety than those in nonclinical populations (Tsao et al., 2009); a point specifically true for those with recurrent abdominal pain (Campo et al., 2004). Although recommended for adults with chronic pain, little attention has been paid to routine screening for anxiety disorders in pediatric chronic pain populations. The primary goal of this study is to quantify the prevalence of anxiety and sub-clinical levels of anxiety in a pediatric chronic pain population. A secondary goal is to examine differences in anxiety symptoms in children with headache and abdominal pain. Methods: Children and adolescents (N = 92; 73.9% female; 79.6% Caucasian) ages 8-18 (M = 14.1, SD = 2.56) completed measures before beginning treatment at a multidisciplinary pain clinic. Included were self-reports of pain location, intensity and duration. Youth also completed the Screen for Child Anxiety Related Disorders (SCARED). The SCARED is a validated child report that yields a total anxiety score and several subscales: panic or somatic symptoms, generalized anxiety, separation anxiety, social anxiety, and school avoidance. Results: Based on clinical cutoff scores (greater than or equal to 25), 34.9% (N = 30) of children and adolescents had total scores indicating a possible anxiety disorder. Within this group, 22 children and adolescents (21.7% of the total sample) scored above a more stringent cutoff (greater than or equal to 30). If we include children and adolescents falling just below the clinical cutoff score (greater than or equal to 20), 43.4% (N = 42) of our sample warrant further assessment of anxiety symptoms. Subscale scores: 21.7% of participants reported elevated panic or somatic symptoms, 24.1% reported elevated generalized anxiety, 19.5% reported elevated separation anxiety, 9.6% reported social anxiety, and 47.6% reported elevated school avoidance. Worst pain level was correlated with child report of total anxiety (r = .26, p < .05) and generalized anxiety symptoms (r = .24, p < .05). Best pain level was correlated with child report of total anxiety, separation anxiety and social anxiety (r range = .24 - .29, p < .05). The two most common primary pain locations reported were head (40.0%) and abdomen (18.9%). These two groups did not differ in age or gender. In comparing these two groups, children with abdominal pain reported higher overall anxiety (t (45) = 2.51, p < .05), panic and somatic complaints (t (45) = 3.21, p < .01), and school avoidance (t (45) = 2.22, p < .05) than children reporting headaches. The two groups did not differ in their reports of pain intensity, however, those with abdominal pain reported experiencing pain for a longer duration than those with headache (t (47) = 2.12, p < .05). Conclusions: Given these findings, anxiety symptoms should be assessed when treating children with chronic pain. Pediatric patients with chronic pain have elevated symptoms in several anxiety-related domains. Children reporting abdominal pain experienced more overall anxiety, panic and somatic complaints, and school avoidance than those who reported headache pain, suggesting possible differences in patterns of comorbidity or etiology.