UC Irvine Environmental Health & Safety: Example Standard Operating Procedures for Hazardous Chemicals and Particularly Hazardous Substances DIMETHYLBENZANTHRACENE (DMBA) #1 Process Topical Application of DMBA. All users must read the Material Safety Data Sheet (www.ucmsds.com ) prior to handling this material. Additional safety information can also be obtained from http://ntpserver.niehs.nih.gov/cgi/iH_Indexes/ALL_SRCH/iH_ALL_SRCH_Frames.html. Enter CAS number: 57-97-6 #2 Hazardous Chemicals/Class of Hazardous Chemicals Dimethylbenzanthracene CAS No. 57-97-6. This chemical is an experimental carcinogen, neoplastigen, tumorigen, and teratogen. Poison by ingestion, intravenous, subcutaneous, intraperitoneal, and intratracheal route. #3 PPE - Personal protective Equipment Wear safety glasses when handling the material. When the chemical is handled as dry material, an N95 HEPA filter respirator must be worn. Contact EH&S for procedures on how to obtain a respirator. MSDS recommends the use of a 0.38 mm thick nitrile gloves (Edmont 37-155 ). . #4 Engineering/Ventilation Controls Use in a “Designated Area” only such as a fume hood. Decontaminate all surfaces after a spill. See spill and decontamination procedures below. #5 Special Handling Procedures and Storage Requirements Protect material from exposure to light. Keep away from oxidizing materials and store under refrigerated temperatures. #6 Spill and Accident Procedures Small Spills: Do not attempt clean-up if you feel unsure of your ability to do so or if you perceive the risk to be greater than normal laboratory operations. Absorb incidental spills with absorbent pads. Collect and submit for waste disposal by EH&S. Large Spills: Notify others in area. Evacuate room/immediate area. If splashed on an individual or in eyes flush for 15 minutes with copious quantities of water. Call EH&S for HazMat response. Post area and prevent unnecessary entry until EH&S response team arrives. Provide assistance to EH&S as requested. If a spill occurs, remove all sources of ignition. Dampen the solid spill of material with acetone and transfer the material to a labeled “Hazardous Waste” container. Use absorbent paper dampened with acetone to pick-up remaining material. Seal contaminated clothing and absorbent paper in a vapor tight plastic bag for hazardous waste disposal. #7 Waste Disposal Dispose contaminated material as hazardous waste. #8 Approval Required Approval required from PI. #9 Decontamination Procedures Solvent wash all contaminated surfaces with acetone followed by washing with soap and water solution. Do not reenter the contaminated area if large spill occurs. #10 Designated Area Handle dry powders inside a fume hood. For more information relevant to completing this form, review thoroughly Chemical Hygiene Plan: Section 5. Training Acknowledgement: I have read, asked questions, and understand the hazards of and safe working procedures for the activity/materials described herein. NAME DATE UC Irvine Environmental Health & Safety: Example These safety training resources, prepared solely for the use of the Regents of the University of California, were provided by a variety of sources. It is your responsibility to customize the information to match your specific operations. Neither the University of California nor any of its employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information, or represents that its use would not infringe privately owned rights. Reference herein to any specific commercial product, process, or service by trade name, trademark, manufacturer, or otherwise, does not necessarily constitute or imply its endorsement, recommendation, or favoring by the University of California. The views and opinions of authors expressed herein do not necessarily state or reflect those of the University of California, and shall not be used for advertising or product endorsement purposes.