The presented Master Thesis was performed at the Institute of Pharmacy and Molecular Biotechnology of the University of Heidelberg (e.g.) and the Max-Planck-Institute for Medical Research in Heidelberg (e.g.) for completion of the Master's program Molecular Biotechnology at the Faculty of Bioscience at the University of Heidelberg in the time from 1st of April to the 31st of October 2008 (e.g.) First Referee: Prof. Dr. ….. Department: Bioanalytic and Molecular Biology Institute of Pharmacy and Molecular Biotechnology University of Heidelberg (e.g.) Second Referee: Dr. ….. Department: Molecular Neurobiology Max-Planck-Institute for Medical Research Heidelberg (e.g.) I herewith declare that 1. 2. 3. I wrote this Master Thesis independently under supervision and that I used no other sources and supporting materials than those indicated; the adoption of quotation from the literature/internet as well as thoughts from other authors were indicated in the thesis; my Master Thesis was not submitted to any other examination. I am aware of the fact that a false declaration will have legal consequences. Place, Date Signature