Drug Information Sheet ("Kusuri-no-Shiori") Revised:3/2005 Information is based on approvals granted in Japan. In some cases, the approved details may vary in countries other than Japan. Brand Name:Rize Tablets 5mg Nonproprietary (Generic) Name:Clotiazepam DESCRIPTION THIS MEDICINE WORKS FOR Dosage Form:tablet (φ6.1mm) Color:white Printings on wrapping:Y-RZ5 Rize soothes nerves, and ease anxiety/tense nerves. Rize helps you fall asleep. Rize relieves excessively tense nerves before surgery. ・Tell your Doctor: - If you ever had any unusual or allergic reaction to any medicines. BEFORE USING THIS MEDICINE - Patients with glaucoma, myasthenia gravis, heart/liver/kidney disease, history of the treatment of strokes and head injury, unable to breath smoothly due to asthma or any lung diseases. - If you are using any other prescription or nonprescription (OTC) medicine. ・Pregnancy/Breast-feeding Make sure your doctor knows if you are already pregnant or are breast -feeding. ・Remove the medicine from the package prior to use. HOW SHOULD THIS MEDICINE BE USED? PRECAUTIONS WHILE USING THIS MEDICINE ・Follow your doctor’s instructions. Take this medicine with a glass of water or lukewarm water. ・If you are ordered to use this medicine on regular schedule and you missed a dose, apply as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. ・DO NOT take a double dose to make up for the missed dose. ・If you took too much Rize, check with your doctor immediately. ・Elderly Person: Follow your doctor's instructions. ・Do not increase or reduce your medication without the instructions of your doctor. This medicine may cause drowsiness, lack of attentiveness, concentration or ability of reflexive motion. Avoid driving a car or operate machinery. Avoid drinking alcohol with this medication. Continued on next page Rize Tablets 5mg ・A medicine may cause some unwanted effects. Stop taking your medicine and check with your doctor immediately if any of the following side effects occur: - If you feel that the effect of the medicine have changed, experience convulsion, shaky hands, loss of sleep, anxiety, hallucination after lessening/stopping your medication. SIDE EFFECT(s) OF THIS MEDICINE - Yellowing of the skin or the whites of the eyes, fatigability. ・Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor: Sleepiness, dizziness, wobbly/falling down when walking, vision disorder, headache, shaky hands, numbness of limbs, unable to articulate properly, ear ringing, dizziness on standing up, fast pulse. Nausea, loss of appetite, gastric pain, constipation, thirst. Rash, itching. Dullness, weakness, muscle pain, joint pain, swelling. ・Check with your doctor/pharmacist if anything is bothersome to you. COMMENT Contact No. of Contact No. of your Doctor your Pharmacist For more detailed information about this medicine, ask your doctor or pharmacist.