Wybrane publikacje pracowników Zakładu:
1. Kozak, W. Regulated decreases of body temperature. In Fever. Basic Mechanisms and
Management. 2nd edition. P.A. Mackowiak, editor. Lippincott-Raven Publ. pp.467-478,
1997.
2. Kozak, W., V. Poli, D. Soszynski, C.A. Conn, L.R. Leon, and M.J. Kluger. Sickness
behavior in mice deficient in interleukin-6 during turpentine abscess and influenza
pneumonitis. Am. J. Physiol. 272:R621-R630, 1997.
3. Leon, L.R., W. Kozak, J. Peschon, M. Glaccum, and M.J. Kluger. Altered acute phase
response to inflammation in IL-1 and TNF receptor knockout mice. Ann. N.Y. Acad. Sci.
813:244-254, 1997.
4. Kozak, W., D. Soszynski, C.A. Conn, K. Rudolph, L.R. Leon, and M.J. Kluger. Soluble
TNF-a receptor prevents decrease of body temperature in mice injected with
indomethacin and lipopolysaccharide. Ann. N.Y. Acad. Sci. 813:264-271, 1997.
5. Kozak, W., D. Soszynski, K. Rudolph, C.A. Conn, and M.J. Kluger. Dietary n-3 fatty acids
differentially affect sickness behavior in mice during local and systemic inflammation. Am.
J. Physiol. 272:R1298-R1307, 1997.
6. Kozak, W., J.J. Klir, C.A. Conn, and M.J. Kluger. Attenuation of lipopolysaccharide fever
in rats by protein kinase C inhibitors. Am. J. Physiol. 273:R873-R879, 1997.
7. Kluger, M.J., W. Kozak, L.R. Leon, and C.A. Conn. The use of knockout mice to
understand the role of cytokines in fever. Clin. Exp. Pharmacol. Physiol. 25:141-144,
1998.
8. Kluger, M.J., W. Kozak, L.R. Leon, D. Soszynski, and C.A. Conn. Fever and Antipyresis.
In: Brain Function in Hot Environment. Sharma H.S., and Westman J., ed. Progress in
Brain Research Vol. 115, pp. 465-475. Elsevier Science Publisher, Amsterdam, 1998.
9. Sopori, M.L., W. Kozak, S.M. Savage, Y. Geng, and M.J. Kluger. Nicotine-induced
modulation of T cell function: implications for inflammation and infection. In: Advences in
Experimental Medicine and Biology, Vol. 402: Drugs of Abuse, Immunomodulation, and
AIDS. Editors: H. Friedman, T.K Eisenstein, J. Madden, and B.M. Sharp. Plenum Press,
New York, 1998, pp. 279-289.
10. Sopori, M.L., W. Kozak. Immunomodulatory effects of cigarette smoke. J. Neuroimmun.
83:148-156, 1998.
11. Kluger, M.J., W. Kozak, C.A. Conn, L.R. Leon, and D. Soszynski. Role of fever in disease.
Ann. N.Y. Acad. Sci. 856:224-233, 1998.
12. Kozak, W., I. Archuleta, K.P. Mayfield, A. Kozak, K. Rudolph, and M.J. Kluger. Inhibitors
of alternative pathways of arachidonate metabolism differentially affect fever in mice. Am.
J. Physiol. 275:R1031-R1040, 1998.
13. Kozak, W., M.J. Kluger, D. Soszynski, C.A. Conn, K. Rudolph, L.R. Leon, and H. Zheng.
IL-6 and IL-1b in fever: Studies using cytokine-deficient (knockout) mice. Ann. N.Y. Acad.
Sci. 856:33-47, 1998.
14. Leon, L.R., W. Kozak, K. Rudolph, and M.J. Kluger. An antipyretic role for interleukin-10 in
LPS fever in mice. Am. J. Physiol. 276:R81-R89, 1999.
15. Kozak, W., K.P. Mayfield, A. Kozak, M.J. Kluger. Proadifen (SKF-525A), an inhibitor of
cytochrome P-450, augments LPS-induced fever and exacerbates prostaglandin-E2
levels in the rat. J. Thermal Biol. 25:45-50, 2000.
16. Mayfield, K.P., D. Soszynski, W. Kozak, A. Kozak, K. Rudolph, and M.J. Kluger. bAdrenergic receptor subtype effects on stress fever and thermoregulation.
Neuroimmunomodulation 6:305-317, 1999.
17. Szewczenko-Pawlikowski, M., W. Kozak. Accumulation of unsaturated lipids in monocytes
during early phase pyrogen tolerance. Biochem. Biophys. Acta 1484:183-194, 2000.
18. Kozak, W., M.J. Kluger, A. Kozak, M. Wachulec, and K. Dokładny. Role of cytochrome P450 in endogenous antipyresis. Am. J. Physiol. 279:R455-R460, 2000.
19. Kozak, W., M.J. Kluger, J. Tesfaigzi, M. Wachulec, A. Kozak, and K. Dokładny. Molecular
mechanism of fever and antipyresis. Ann. N.Y. Acad. Sci. 917:121-134, 2000.
20. Kluger, M.J., W. Kozak, and K.P. Mayfield. Fever and immunity. In
Psychoneuroimmunology, 3rd edition, edited by R. Ader, D. Felten and N. Cohen.
Academic Press, San Diego. Vol. 1, pp. 687-701, 2001.
21. Foster JE, Gott K, Schuyler MR, Kozak W, Tesfaigzi Y. LPS-induced neutrophilic
inflammation and Bcl-2 expression in metaplastic mucous cells. Am J Physiol Lung Cell
Mol Physiol. 2003 Aug;285(2):L405-14. Epub 2003 Apr 18.
22. Kozak W, Kozak A. Genetic Models in Applied Physiology. Differential role of nitric oxide
synthase isoforms in fever of different etiologies: studies using Nos gene-deficient mice. J
Appl Physiol. 2003 Jun;94(6):2534-44. Epub 2003 Jan 31.
23. Kozak W, Aronoff DM, Boutaud O, Kozak A. 11,12-epoxyeicosatrienoic acid attenuates
synthesis of prostaglandin E2 in rat monocytes stimulated with lipopolysaccharide. Exp
Biol Med (Maywood). 2003 Jul;228(7):786-94.
24. Kozak W., V. Fraifeld. Non-prostaglandin eicosanoids in fever and anapyrexia. Frontiers
in Bioscience 9:3339-3355, 2004.
25. Wrotek S., Dąbrowska G., Tretyn A. Czy istnieje roślinny homolog zwierzęcego peptydu
natriuretycznego? Postępy Biologii Komórki 32:449-462, 2005
26. Kozak, W., Wrotek, S., Kozak, A., Pyrogenicity of CpG-DNA in mice: Role of interleukin-6,
cyclooxygenases, and nuclear-factor-kappa-B. Am J Physiol Regul Integr Comp Physiol.
290(4):R871-80, 2006
27. Wrotek, S., Dąbrowska, G., Tyburski, J., Tretyn, A., There is no proof for the existence of
atrial natriuretic peptide (ANP) homologue in a plant Pharbitis nil, Medical and Biological
Sciences, 20(4): 181-186, 2006
28. Walentynowicz, K., Szefer, M., Wojtal, B., Terlecki, P., Wrotek, S., Kozak, W. Role of
prostaglandins in heme-induced fever. J Physiol Pharm 57: 73-82, 2006
29. Kozak, W., Wrotek, S., Walentynowicz, K., Hypoxia-induced sickness behaviour. J Physiol
Pharm 57: 35-50, 2006
30. Kozak, W., Wrotek, S., Walentynowicz, K., Waszak, P., Fever and symptoms of sickness
are present in mice lacking functional B and T lyphocytes, Acta Biologica Cracoviensis 48:
9-20, 2006
31. Kozak W, Kozak A, Johnson MH, Elewa HF, Fagan SC: Vascular protection with
candesartan after experimental acute stroke in hypertensive rats: A dose- response study.
J. Pharmacol. Exp. Therap. 326:773-782, 2008.
32. Wrotek S., Kamecki K., Kwiatkowski S., Kozak W. Cancer patients report a history of
fewer fevers during infections than healthy controls. Journal of Pre-Clinical and Clinical
Research, 3: 031-035, 2009.
33. Kozak W. Geneza gorączki. Biologiczne mechanizmy i praktyka medyczna. Wydawnictwo
Naukowe UMK, 2009.
34. Kowalczewska M., Wrotek. S., Jedrzejewski T., Kozak W. Cancer cachexia: mediating
factors and the effect of eicosapentaenoic acid dieting. Journal of Pre-Clinical and Clinical
Research 4 (2): 108-111, 2010.
35. Wrotek S., Jedrzejewski T., Potera-Kram E., Kozak. W. Antipyretic activity of NAcetylcysteine. Journal of Physiology and Pharmacology, 62 (6): 669-675, 2011.
36. Żbikowska E., Wrotek S., Cichy A., Kozak W. Thermal preferences of wintering snails
Planorbarius corneus (L.) exposed to lipopolysaccharide and zymosan. Journal of
Invertebrate Pathology, doi: 10.1016/j.jip.2012.08.011, 2012.
37. Jedrzejewski T., Wrotek S., Piotrowski J., Kozak W. Silver nanoparticles augment
releasing of pyrogenic factors by blood cells stimulated with LPS. Central European
Journal of Biology 9 (11): 1058-1067, 2014.
38. Jedrzejewski T., Piotrowski J., Wrotek S., Kozak W. Polysaccharide peptide induces a
tumor necrosis factor-α-dependent drop of body temperature in rats. Journal of Thermal
Biology 44: 1-4, 2014.
39. Piotrowski J., Jedrzejewski T., Kozak W. Heme oxygenase-1 induction by cobalt
protoporphyrin enhances fever and inhibitis pyrogenic tolerance to lipopolysaccharide.
Journal of Thermal Biology 45: 69-74, 2014.
40. Wrotek S., Rosochowicz T., Nowakowska A., Kozak W. Thermal and motor behavior in
experimental autoimmune encephalitis in Lewis rats. Autoimmunity 47 (5): 334-340, 2014.