Genome Medicine is an online peer-reviewed journal which publishes open access research articles of outstanding quality in all areas of medicine studied from a genomic or post-genomic perspective. The journal has a special focus on the latest technologies and findings that impact on the understanding and management of human health and disease. In addition to publishing high-quality research, Genome Medicine serves the international research community as a forum for the discussion and critical review of information about all areas of medicine informed by genomic research. Subjects include, but are not limited to: Significant advances in the understanding of the genetics, genomics, and epigenetics of disease Computational and systems approaches, including proteomics, metabolomics and transcriptomics, to the understanding and management of disease Genomic epidemiology and public health genomics The application of genomic and post-genomic technologies to clinical practice, with special emphasis on diagnostics and therapeutics Personalized medicine Ethical, social and legal issues relating to genomic medicine and personalized medicine Content overview Genome Medicine contains the following types of articles: Research articles: reports of data from exceptional original research. These articles will form the major content of the journal. Reviews: include systematic and substantial coverage of mature subjects, rapid coverage of fast-moving areas, evaluations of progress in specified areas, and critical assessments of emerging technologies. Reviews will generally be commissioned by the editorial staff, though suggestions of topics are always welcome. Commentaries: short, focused and opinionated articles on any subject within the journal's scope. These articles usually relate to contemporary issues and are often written by opinion leaders invited by the Editorial Board. Correspondence: may discuss material published in Genome Medicine or particular issues of general interest to the readership. They may also present a community announcement within the field of genomic and post-genomic medicine. Meeting reports: short descriptions of a conference that an author has attended, which should focus on the key developments presented and discussed at the meeting. These articles are usually commissioned but reports and suggestions may also be submitted for the editors' consideration. Peer review policies Suitability of research for publication in Genome Medicine is dependent primarily on the scientific validity and coherence of the work, as well as broad interest, as assessed by reviewers and Editors. Although Genome Medicine will not make general interest level an absolute criterion for publication, it aims to provide its readership with the highest quality research and information in genomic and post-genomic medicine, and will therefore focus on articles of general and outstanding interest. All submitted research papers are subject to immediate rapid screening by the editors, in consultation with the Editorial Board if appropriate, to ensure they fall within the scope of the journal. Contributors who are in doubt about the suitability of their paper are welcome to send a presubmission enquiry. The editors will provide an initial response to all presubmission enquiries and submitted articles within five working days. Manuscripts will be reviewed by internationally recognized experts in the fields of genomic and post-genomic medicine selected in part from our Editorial Board. Genome Medicine operates an anonymous peer review process. Reviews will be rapid and the suitability of a paper for publication will be assessed solely on criteria of scientific excellence. The editors will make every effort to give authors a decision following peer review within four weeks of an article's submission. Articles are published electronically as promptly as possible after they are accepted, and within one month of acceptance.