-Professeur Jean-Pierre GIES Faculté de Pharmacie Equipe de Signalisation cellulaire UMR 7175-LC1 74, Route du Rhin, BP 24 67401 ILLKIRCH CEDEX Tél. (33) 03 90 24 41 40 Bonjour, Nous vous adressons l'annonce d'un Séminaire que nous organisons le Vendredi 13 juillet prochain. Nous vous invitons à transmettre cette information à vos équipes et vous remercions de bien vouloir nous informer du nom des participants afin d'organiser leur venue. Restant à votre disposition pour tout complément d'information et dans l'attente de vous lire, Meilleures salutations, Martine Brandt Transgene SA 11 rue de Molsheim F - 67082 Strasbourg Cedex Tel : +33 (0)3.88.27.91.73 Fax : +33 (0)3.88.27.91.41 brandt@transgene.fr www.transgene.fr SEMINAR ANNOUNCEMENT Friday, July 13th 11.00 am - 12.30 am : Seminar Room C 2.00 pm - 4.30 pm : Round Table Room C Philip M. Arlen, M.D. Director, Clinical Research Group Laboratory of Tumor Immunology and Biology Center for Cancer Research, National Cancer Institute Title: "Combinatorial therapies utilizing cancer Vaccines" Round Table open to all Publications Madan RA, Lieberman R, Gulley JL, Dahut W, Arlen PM. Significant Prostate-Specific Antigen (PSA) Response to Low-Dose Ketoconazole in a Patient With Non-Metastatic AndrogenIndependent Prostate Cancer (AIPC) and a Review of the Literature. Am J Ther. 2007 May-Jun;14(3):310-3. PMID: 17515709 [PubMed in process] Yokokawa J, Bera TK, Palena C, Cereda V, Remondo C, Gulley JL, Arlen PM, Pastan I, Schlom J, Tsang KY. Identification of cytotoxic T-lymphocyte epitope(s) and its agonist epitope(s) of a novel target for vaccine therapy (PAGE4). Int J Cancer. 2007 Aug 1;121(3):595605. PMID: 17397028 [PubMed - in process] Madan RA, Arlen PM, Gulley JL. PANVAC-VF: poxviral-based vaccine therapy targeting CEA and MUC1 in carcinoma. Expert Opin Biol Ther. 2007 Apr;7(4):543-54. Review. PMID: 17373905 [PubMed - indexed for MEDLINE] Wu SL, Jones E, Gulley JL, Arlen PM, Chen CC, Figg WD, Dahut WL. Routine interval computed tomography to detect new soft-tissue disease might be unnecessary in patients with androgenindependent prostate cancer and metastasis only to bone. BJU Int. 2007 Mar;99(3):525-8. Epub 2006 Nov 28. PMID: 17155971 [PubMed - indexed for MEDLINE] Leonard GD, Dahut WL, Gulley JL, Arlen PM, Figg WD. Docetaxel and thalidomide as a treatment option for androgen-independent, nonmetastatic prostate cancer. Rev Urol. 2003;5 Suppl 3:S65-70. PMID: 16985953 [PubMed - in process] Arlen PM, Dahut WL, Gulley JL. Immunotherapy for prostate cancer: what's the future? Hematol Oncol Clin North Am. 2006 Aug;20(4):965-83, xi. Review. PMID: 16861126 [PubMed - indexed for MEDLINE] Lattouf JB, Arlen PM, Pinto PA, Gulley JL. A phase I feasibility study of an intraprostatic prostate-specific antigen-based vaccine in patients with prostate cancer with local failure after radiation therapy or clinical progression on androgen-deprivation therapy in the absence of local definitive therapy. Clin Genitourin Cancer. 2006 Jun;5(1):89-92. No abstract available. PMID: 16859586 [PubMed indexed for MEDLINE] Arlen PM, Pazdur M, Skarupa L, Rauckhorst M, Gulley JL. A randomized phase II study of docetaxel alone or in combination with PANVAC-V (vaccinia) and PANVAC-F (fowlpox) in patients with metastatic breast cancer (NCI 05-C-0229). Clin Breast Cancer. 2006 Jun;7(2):176-9. No abstract available. PMID: 16800982 [PubMed indexed for MEDLINE] Ahlers CM, Camphausen K, Citrin D, Arlen PM, Gulley JL. A pilot trial of a carcinoembryonic antigen/ TRICOM-based vaccine and radiation to liver metastases in patients with carcinoembryonic antigen-positive solid tumors. Clin Colorectal Cancer. 2006 May;6(1):72-5. No abstract available. PMID: 16796796 [PubMed indexed for MEDLINE] Tarassoff CP, Arlen PM, Gulley JL. Therapeutic vaccines for prostate cancer. Oncologist. 2006 May;11(5):451-62. Review. PMID: 16720845 [PubMed - indexed for MEDLINE] Madan RA, Gulley JL, Arlen PM. PSA-based vaccines for the treatment of prostate cancer. Expert Rev Vaccines. 2006 Apr;5(2):199-209. Review. PMID: 16608420 [PubMed - indexed for MEDLINE] Arlen PM, Gulley JL. Docetaxel-based regimens, the standard of care for metastatic androgen-insensitive prostate cancer. Future Oncol. 2005 Feb;1(1):19-22. PMID: 16555972 [PubMed - indexed for MEDLINE] Arlen PM, Gulley JL, Parker C, Skarupa L, Pazdur M, Panicali D, Beetham P, Tsang KY, Grosenbach DW, Feldman J, Steinberg SM, Jones E, Chen C, Marte J, Schlom J, Dahut W. A randomized phase II study of concurrent docetaxel plus vaccine versus vaccine alone in metastatic androgen-independent prostate cancer. Clin Cancer Res. 2006 Feb 15;12(4):1260-9. PMID: 16489082 [PubMed - indexed for MEDLINE] Garnett CT, Greiner JW, Tsang KY, Kudo-Saito C, Grosenbach DW, Chakraborty M, Gulley JL, Arlen PM, Schlom J, Hodge JW. TRICOM vector based cancer vaccines. Curr Pharm Des. 2006;12(3):351-61. Review. PMID: 16454749 [PubMed - indexed for MEDLINE] Madan RA, Arlen PM. Abiraterone. Cougar Biotechnology. IDrugs. 2006 Jan;9(1):49-55. PMID: 16374734 [PubMed - indexed for MEDLINE] Dahut WL, Lakhani NJ, Gulley JL, Arlen PM, Kohn EC, Kotz H, McNally D,Parr A, Nguyen D, Yang SX, Steinberg SM, Venitz J, Sparreboom A, Figg WD. Phase I clinical trial of oral 2methoxyestradiol, an antiangiogenic and apoptotic agent, in patients with solid tumors. Cancer Biol Ther. 2006 Jan;5(1):22-7. Epub 2006 Jan 22. PMID: 16357512 [PubMed - indexed for MEDLINE] Arlen PM, Kaufman HL, DiPaola RS. Pox viral vaccine approaches. Semin Oncol. 2005 Dec;32(6):549-55. Review. PMID: 16338420 [PubMed - indexed for MEDLINE] Hodge JW, Greiner JW, Tsang KY, Sabzevari H, Kudo-Saito C, Grosenbach DW, Gulley JL, Arlen PM, Marshall JL, Panicali D, Schlom J. Costimulatory molecules as adjuvants for immunotherapy. Front Biosci. 2006 Jan 1;11:788-803. Review. PMID: 16146771 [PubMed indexed for MEDLINE] Posadas EM, Gulley J, Arlen PM, Trout A, Parnes HL, Wright J, Lee MJ, Chung EJ, Trepel JB, Sparreboom A, Chen C, Jones E, Steinberg SM, Daniels A,Figg WD, Dahut WL. A phase II study of perifosine in androgen independent prostate cancer. Cancer Biol Ther. 2005 Oct;4(10):1133-7. Epub 2005 Oct 1. PMID: 16138006 [PubMed indexed for MEDLINE] Arlen PM, Gulley JL, Todd N, Lieberman R, Steinberg SM, Morin S, Bastian A, Marte J, Tsang KY, Beetham P, Grosenbach DW, Schlom J, Dahut W. Antiandrogen, vaccine and combination therapy in patients with nonmetastatic hormone refractory prostate cancer. J Urol. 2005 Aug;174(2):539-46. PMID: 16006888 [PubMed - indexed for MEDLINE]