INTRODUCTORY BIOLOGY 151/152 FACULTY-STAFF MEETING January 18, 2005 Background Materials Contents I. II. III. Student learning goals and objectives (from May 2004 faculty-staff meeting) Science content (from August 2004 half-day retreat) Suggestions for course review (from December 2004 meeting) I. Student learning goals and objectives (May 2004) Introductory Biology 151/152 will provide students with a solid foundation in the fundamental concepts and knowledge base of modern biology and help students develop the skills that are integral to the process of science. This course provides a coherent framework for understanding biology and prepares students for their upper-level courses. We hope also to encourage in students an intellectual excitement for biology and for science in general. General comment Science is hierarchical & historical knowledge builds on knowledge, and process u far process. We are providing the FOUNDATION upon which the rest of a student’s biological growth stands. Both process AND content are crucial. Provide a knowledge base Provide exposure to the breadth of the field of biology. Provide knowledge about the scope of biology—atoms to ecosystems—and about the many ways to be a biologist. To learn the nature of Nature. Provide a coherent framework for understanding major concepts in biology. To provide strong grounding/understanding in fundamental concepts of modern biology. To provide a basic understanding of major biological concepts/knowledge. o To have the very basics of biology understood so that all future learning can strengthen & add to biological knowledge. o To be able to identify what is known & isn’t known about our understanding of biology. Provide a solid foundation of knowledge base & skills to prepare students for upper courses. To poise a student well for success in upper level bio courses. o To introduce concepts & vocabulary to prepare for upper level courses in biology. 1 To give a well-rounded perspective of biology—appreciation of all areas/topics not just a student’s intended career direction To educate biologically literate citizens. Make connections-- within biology and to other sciences Make conceptual connections across all levels of organization in biology. Emphasize that t biology is about ideas more than facts Enable students to be able to cite examples of paradigm shifts in biology (understand that “facts” change). Describe with examples of multiple ways in which biological sub disciplines are all interconnected. Appreciate the central importance of primary producers. Make conceptual and content linkages with other learning, especially in chemistry, physics, applied mathematics Spark interest/passion/excitement for biology Ignite/reinforce a passion for study of biology/nature. Communicate that biology is fascinating. Get excited about science! Spark interest and curiosity about the living world Generate interest in how a knowledge of biology is essential to global citizenship Develop skills Practice in what biologists actually do to “study biology” or do research. Understanding of what biologist do—process of science. To understand the scientific method and to know how to critically evaluate scientific data. Ability to think like a scientist, apply scientific method. Understand the scientific method. Reason quantitatively. o To learn how Nature is studied. o Begin development of scientific/analytical skills—What questions do you need answers to? o What information do you need to answer them? What will you do with that information once you have it? o Develop skills in identifying/asking questions & determining how to solve them. o Be able to integrate disparate information. What characterizes biological thinking at a strategic cultural level. E.g. X levels of analysis. Interest in richness of types. Understanding of the scientific process. Process of science—vitally important, but it can be conveyed fairly quickly, both in lecture & lab—say two weeks. The basic knowledge & philosophy of each major area should be clearly presented and they are often different. There are many ways of being a valid biologist. 2 Provide a learning environment where students can acquire the needed background and skills necessary to solve biological problem. Provide training— professional skills (writing, group work, problem solving, stats). Develop o learning skills o communication o teamwork. o Practice in using biological knowledge/concepts to solve novel problems. Use writing to help students get their understanding of biology processes etc. How to take notes, review material, & take exams. Understand applications of biology, scientific underpinning of real-world issues Application of Biology 151/2 to real world. Critical thinking, problem-solving, ability to generate questions surrounding a problem. Understand the science component/underpinning of current issues (e.g. climate change). Use information to critique o news o choices – ex. food, lawn care, health. o “voting”- good citizenship. Be able to take a ‘devil’s advocate’ position on issues. (Value of challenge to status quo). Be able to relate information to practical/every day issues. (Communicate with non-scientists). How to apply their knowledge. o Scientific method applied to biology. o Be able to apply scientific method (reasoning) to biological issues. o Understand the basis of our current knowledge of biology. o Appreciate the unity of biology due to the “central dogma”. Science content ideas that were also suggested Symbiosis def. & examples. Evolution as a unifying concept. o DNA—RNA—Protein o + details o + exceptions Major Domains/kingdoms of life—Defin. & Examples. Understand how natural selection works. Understand how pops evolve. What a phylogeny is & how to interpret one. Large patterns, timing, in history of life. Apply logic to biological problems. How we are affecting our environment. Be able to articulate the important biological concepts that ? fine. The impact of human activity on the biosphere and the feed back of that effect on human civilization (s). 3 Evolution as a creative process. What is the raw material? Where is the action? How chemical/physical laws confine behavior at cellular/molecular levels. Parallels—how organisms have arrived at different solutions to common problems. The history of life on earth. The “fit” between form and function. 4 II. Science content of course sections from August 2004 half-day retreat Participants: Nicole Parma, Linda Graham, Carlos Peralta, Tony Stretton, Steve Gammie, Jenny Bauman, Andrea Gargas, Bob Jeanne, Tim Allen, Jean Heitz, Bob Goodman, John Kirsch, Donna Fernandez, David Baum, Sharon Stern, Dave Abbot, Milo Wiltbank, Stan Dodson, Monica Turner, Brian Manske Ecology, Evolution and Diversity Diversity Exposure to life's diversity – 3 domains Distinctions among major groups (prokaryotes versus eukaryotes, multiple origins, multicellularity) Unity of Earth's life Players in the ecological theater Role of organisms in influencing life's diversification (O2, CO2, etc) Humans are primates Life originated once Plastids and mitochondria are endosymbiotic bacteria Eukaryotes are a clade derived from a prokaryotic grade (three domains) Oxygen in the atmosphere is all due to cyanobacteria There are many prokaryotic lineages and many eukaryotic clades beside animals, plants, and fungi Animals, plants and fungi represent independent origins of multicellularity Life cycles vary among eukaryotes (animals have just one kind) “Invertebrates” are paraphyletic Arthropods, mollusks, annelids, cnidarians, sponges, and chordates are distinct groups of animal Land plants are just one of several plant-like eukaryotic lineages Humans are mammals and primates and have many features of their closest relatives Life has a deep history (humans a shallow one) Evolution Natural selection and other mechanisms of evolution (e.g. genetic drift) Darwin's ideas as paradigm shift Evolution is a property of populations, not individuals. Hardy-Weinberg and assumptions Phylogeny as model of evolutionary pattern o Tree thinking o Splitting more common than fusion Chance and order 5 Speciation Evolution is not Natural Selection What is a phylogeny and how are they interpreted Hardy-Weinberg and its assumptions Natural selections converts stochastic patterns into order What Darwin represented a paradigm shift Genetic drift as an inevitable outcome of finite populations Speciation is required for a tree-like form Evolution involves changes in the frequency of genes in populations (not changes in organisms during their life-cycle) Natural selection is very effective given enough time Natural selection can only act on heritable variation Ecology (Reference ecology vs environmentalism) Definition of ecology Type of ecology Basic population dynamics (why and how of equations) Matter and energy flow and cycling (biotic and abiotic) Dynamic ecosystems (SA/V) Physiological ecology (adaptations & budget) o Behavior Data collection in ecology Interactions 6 Cell and Genetics Containment – Cell structure and function Systems o DNA o Regulation o Bioinformatics Response o Cell communication o Metabolism o Mutation Propagation o Inheritance o Genomics Evolution 7 Student "Views" of Science (vs faculty/scientists) Evolution, diversity Models (Uses, limitations) Levels of "causation" Systems, emergent properties Dynamics/Interactions\ Biology is a foreign language Importance of making assumptions explicit Quantitation is useful/necessary Accepted scientific understanding changes over time Structure is related to function; Function is about evolution, not teleology. Unity and Diversity ____________________________________ Integrating systems Homeostasis and feedback Sensory Perception The molecular basis of complexity (Evolution) Structure – Function relationships Transport systems: Bulk flow/plumbing Cell communication Gas Exchange Water relations Transport Systems: Pumps/Channels/transporters Roles of Models and Quantitative Biology Role of Paradigms 8 Notes from general discussion at end of session What’s missing? ethology animal development immunology Ideas for unifying Consider presenting the notion of a system at the beginning of 151 Emergent properties; all levels of scale; and evolution as explicit themes Consider providing a broad picture of the history of biology meaning how we came to know/understand what we know today? Possibly touch again at the end of 152? Explanations in science change—need to appreciate current state of knowledge, and that it will change Scientists make observations and develop questions or problems based on these Students approach the class, etc. as wanting to know answers/solve problems Question of uncertainty Problem solving How would you attack the problem? What do you need to know to solve the problem? What don't we know? Ideas of models/paradigms – cast this as an opportunity Understand model; recognize that it doesn't necessarily apply to all organisms Learning basic ways of learning/understanding systems Statistical hypothesis testing Role of quantitative models and experimental model systems in science—models as rigorous representation of knowledge and as testable hypotheses. Quantification is essential in science. Biological structure and function are related! Biology as a foreign language—lots of new terms, need to learn the language—why we have it! Systems Containment – Inherent properties of components and interactions Various levels of complexity: Flows/Feebacks Response = properties of components Propagation = dynamics Idea of systems 9 Dynamics Interactions – Homeostasis/feedback Range of scales – Ecosystem to molecules Evolution -Diversity├ -- Molecules Organisms Ecosystems Major transitions: Single celled → Multicelled → Vast diversity Levels of organization Emergent Properties Basket of molecules and cells → organisms with properties different from individual components (It's not the description of the component parts, but how they interact.) Causation – Two levels of: 1) How it works – proximate 2) What is it for, i.e. what is the adaptive value – ultimate Linguistics (e.g UUU) vs Thermodynamics (mechanisms required to put them together). 10 III. Suggestions from 151/152 for questions/issues to address in a program review Participants: Sarah Christofferson, Jean Heitz, Allison Kolby, Sheila ___, Herb Wang, Elaine Klein, Brian Manske, Tony Stretton, Sharon Stern, Karen Steudel, Steve Gammie, Donna Fernandez, Edgar Spalding, John Kirsch, Carlos Peralta, Seth Blair, Stan Dodson, Andrea Gargas, Tom Sharkey, Bob Goodman, Monica Turner Course audience and goals: Who are out students? What role does 151-152 play for undergraduates in biology? How well does 151-152 prepare students for subsequent courses etc? Hard look at syllabus/content. Facilitating a learning community. Content – Lab focus – How to develop a more cohesive lab experience? Professional skills development for students Advantages of writing requirement? 152 research experience? Statement of vision for course? Nuts and bolts—how it operates: Lecture size – 200 vs. 400 Documentation about 151-152 o Syllabus o Faculty o Enrollment o Organization Is lab/lec/discussion paradigm the best? Integration within and between sectionsLab/Lec/Discussion integration Documentation of learning Adequacy of faculties? Resources available to keep labs up to date. Is budget appropriate compared to other courses? Is staffing appropriate? Mechanism to get faculty together to think collectively on issues of content/pedagogy etc. How can we get better evaluations from students? o Focus groups? Comparison with other courses on campus – large enrollment and biology courses peer institutions TA workload issues? Coordinator workload issues, and how positions are structured? Administration and adaptation 11 How do we set up mechanism to encourage change over time? Chain of command? To what extent and how well are chairs compensated? Elimination of Comm B requirement from CALS? Teaching load issues – faculty How does the course want to define faculty participation Faculty ownership/commitment/recruitment. Correct distribution from contributing units? Comment: How to preserve what is good in the face of expansion? Be careful to retain what is good/valuable! Beware of change for its own sake. 12