Ames Symposium Pre-conference Workshop

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2nd Bruce Ames International Symposium
on Nutritional Genomics:
Resolving the Diet-Gene Paradox
Pre-Symposium Workshops
12 October 2007
WORKSHOP 1A (ARC BALLROOM A)
Title:
Fundamentals of Nutritional Genomics – a 2007 Update
Coordinators:
Jim Kaput, PhD and Ruth DeBusk, PhD, RD
Summary:
This workshop will present background information on
genetics, epidemiology, and nutrition concepts important for
understanding the latest results in nutritional genomics. Included
will be topics associated with or supplementing the presentations at
the 2nd Bruce Ames International Symposium on Nutritional
Genomics including gut and brain peptides involved in appetite,
new associations of genes and disease (type 2 diabetes,
cardiovascular), and mechanisms of epigenetics.
Target audience:
Dietitians, nutritionists, nurses, physicians, postdoctoral
researchers, graduate students in nutrition, biological science, or
medicine/dentistry/nursing/pharmacy, and other postgraduate
nutrition professionals, health care professionals, and symposium
attendees interested in acquiring additional background knowledge
in nutritional genomics and its applications prior to the symposium.
Workshop Schedule
Time
8:00 – 8:30
8:30 – 9:30
9:30 – 10:00
10:00 – 10:30
10:30 – 11:15
11:15 – 12:00
12:00 – 12:30
Hours
Topic
0.5
Introduction to nutrigenomics through the 5 tenets
1.00
The basics of genetics, epistasis, epigenetics
0.30
Updates on gene associations in diabetes, CVD, and
other diseases
0.50
Break
0.75
Appetite peptides in nutrigenomics
0.75
Evolving strategies in nutritional genomics research:
Hormesis. homeostatic challenges, participatory research
0.50
Question-and-answer period and workshop evaluation
2nd Bruce Ames International Symposium
on Nutritional Genomics:
Bruce Ames Pre-Symposium Workshops, October 12, 2007
1
Resolving the Diet-Gene Paradox
Pre-Symposium Workshops
12 October 2007
WORKSHOP 2A (ARC BALLROOM A)
Title:
Nutritional Genomics: Applications and Practice
Presenters:
Ruth DeBusk, PhD, RD; Colleen Fogarty Draper, MS, RD
Summary:
This workshop is designed to provide the basics of nutritional
genomics for those interested in the practical applications of
this emerging science and is particularly appropriate for
those interested in the clinical applications.
Target audience:
Registered dietitians and other postgraduate nutrition
professionals; other health care professionals, graduate and
undergraduate students in nutrition, biological science, or
medicine/dentistry/nursing/pharmacy; and symposium
attendees interested in developing a background in
nutritional genomics and its varied applications prior to the
symposium
Workshop Schedule:
Time
1:15 – 1:45
1:45 – 3:00
3:00 – 3:25
3:25 – 3:30
3:30 – 4:45
4:45 – 5:00
5:00 – 5:15
Hours
Topic
0.5
Fundamentals of nutritional genomics
1.25 Molecular nutrition: mechanisms by which environmental
factors communicate with the genetic material
0.25 Nutrigenetic testing and other methodology used in
nutritional genomics research and applications
0.25 Break
1.25 Applications of nutritional genomics
0.25 Ethical, legal, and social issues
0.25 Question-and-answer period and workshop evaluation
Bruce Ames Pre-Symposium Workshops, October 12, 2007
2
2nd Bruce Ames International Symposium
on Nutritional Genomics:
Resolving the Diet-Gene Paradox
Pre-Symposium Workshops
12 October 2007
WORKSHOP 2B (ARC BALLROOM B)
Title:
Nutritional Epigenomics: What Your Grandmother Didn’t Tell You
about Nutrition and Health.
Coordinators:
Raymond Rodriguez, PhD and Fred Chedin, PhD
Summary:
This workshop will present background information on the role of
epigenetics as a modulator of diet/gene interactions and its impact
on long-term health outcomes. The fundamentals of DNA
methylation, chromosome imprinting and chromatin modification will
be discussed. Also to be covered are the health consequences of
epigenetic drift and loss of imprinting. The role of diet in
“reprogramming” the epigenome will be discussed. This workshop
will run concurrently with Workshop 2A.
Target audience:
Dietitians, nutritionists, nurses, physicians, postdoctoral
researchers, graduate students in nutrition, biological science, or
medicine/dentistry/nursing/pharmacy, and other postgraduate
nutrition professionals, health care professionals, and symposium
attendees interested in acquiring additional background knowledge
in nutritional genomics and its applications prior to the symposium.
Workshop Schedule:
Time
1:30 – 2:00
2:00 – 2:30
2:30 – 3:00
3:00 – 3:15
3:15 – 4:00
4:00 – 4:30
4:30 – 5:00
Hours
0.5
1.00
0.30
0.25
0.75
0.55
0.50
Topic
Introduction to nutritional epigenomics
The basics of DNA methylation
The basics of the histone code and gene expression
Break
Loss of imprinting and epigenetic drift
Role of diet in “reprogramming” the epigenome
Question-and-answer period and workshop evaluation
Bruce Ames Pre-Symposium Workshops, October 12, 2007
3
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