D Diisseeaasseess ooff tthhee SSkkiinn Dermatophytosis Dermatophytosis is an infection of keratinized tissue (skin, hair, and claws) by one of the three genera of fungi Epidermophyton, Microsporum, and Trichophyton. Microsporum canis is the most common infection. Clinical Symptoms Kittens are most commonly affected. Lesions consist of focal alopecia, scaling, and crusting; most infections occur around the ears and face or on the extremities. The hair becomes brittle. Feline miliary dermatitis with pruritis is occasionally observed. In dogs the lesions include alopecia, scaly patches with broken hairs and dogs may also develop regional or generalized folliculitis with papules and pustules. Diagnosis Direct smear, culture and clinical signs are sufficient; the Wood's lamp is useful in establishing a tentative diagnosis. Treatment and Prevention Management Non-drug treatment Dermatophytosis in dogs and shorthaired cats is usually self-limiting, but resolution can be hastened by treatment. Drug treatment First Line: Miconazole 1% solution, q 1-2 h, then q 3-4 h after 34 days. In chronic or severe cases use Griseofulvin in dogs 25-100 mg/kg once daily or divided in two doses; in cats 25-50 mg/kg daily, also divided doses. Treatment should continue for 2-4 wk past clinical cure. S/E, C/I, D/F, D/I, see page 296. Alternative: Ketoconazole 10 mg/kg, continue for 2-4 wk after clinical cure. S/E, C/I, D/F, D/I, see page 296 or Itraconazole at 5 mg/kg, daily should be continued for 2-4 wk past clinical cure. S/E, C/I, D/F, D/I, see page 296 Prophylaxis: Avoid contact with infected pets. Public health significance: It is zoonotic and one has to take care during handling of infected dogs. Fleas and Flea Allergy Dermatitis Fleas have piercing mouthparts that they insert into the skin of their host to feed on blood. Species commonly infest dogs and cats: Ctenocephalides felis (the cat flea), C. canis (the dog flea), Pulex simulans (a flea of small mammals), and Echidnophaga gallinacea (the poultry sticktight flea). However, by far the most prevalent flea on dogs and cats is C. felis. Fleas cause flea allergy dermatitis, are vectors of typhus-like rickettsiae and intermediate host for filarid and cestode parasites. Clinical Symptoms In Flea allergy dermatitis (FAD) pruritus is observed. In dogs, papulocrustous lesions distributed on the lower back, tailhead, and posterior and inner thighs. Dogs may be particularly sensitive in the flanks, caudal and medial thighs, ventral abdomen, lower back, neck, and ears. Affected dogs are likely to be restless and uncomfortable, spending much time scratching, licking, rubbing, chewing, and even nibbling at the skin. Hair may be stained brown from the licking and is often broken off. Common secondary lesions include areas of alopecia, erythema, hyperpigmented skin, scaling, papules, and broken papules covered with reddish brown crusts. In cats, papule, which often becomes crusted is observed on the back, neck, and face. Pruritus may be severe, evidenced by repeated licking, scratching, and chewing. Cats with FAD can have alopecia, facial dermatitis, exfoliative dermatitis, and “racing stripe” or dorsal dermatitis. Diagnosis History, clinical signs, presence of fleas or flea excrement, results of intradermal testing. Treatment and Prevention Management Drug treatment: First line: Microencapsulated chlorpyrifos (see accompanying insert for application). Permethrin (see accompanying insert for application). Al ternative Non-encapsulated chlorpyrifos (see accompanying leaflet for application). Second line: Organophosphates, carbamates, pyrethroids, for dosage, S/E, C/I, D/F, D/I, see External Parasites of Cattle: Acaricides. For seconday infection Antibiotics; for dosage, S/E, C/I, D/F, D/I, see page 304. plus Prednisolone 0.5-1.0 mg/kg daily, tapering the dosage and using alternate-day therapy until the lowest dose possible that still controls the pruritus. S/E, C/I, D/I and D/F see page 306. Note: Anti-inflammatory therapy should never be used as a substitute for flea control. Fleas are vectors for zoonotic diseases and control should be implemented.