Dr. Dileep Khandekar (M.Sc,PhD) E-Mail: dileepkhandekar@hotmail.com Mobile: 09773875074 PROFESSIONAL SYNOPSIS A well experienced professional with 6.0 years of experience in chemistry Research & Development, and 2 years teaching experience to the M.Sc and B.Sc students. Knowledge Management, Project Management & Execution. Well versed with the multistep synthesis, characterisation and the applications of a wide range of heterogeneoushomogeneous Catalysts and organic/bioorganic reactions for chemical transformations ranging from small organic molecules to functionalised heterocycles. ACADEMICS Ph. D. in BioChemistry from University of Milan, Italy in December 2005. Research Guide: Prof.Sandro Sonnino ( Department of Chemistry, Biochemistry and Biotechnology ,University Of Milan, Italy.) Scientific Project: The project was proposed to synthesis of GM3-oligosaccharide antigen as a cancer vaccine Master of Science (Organic Chemistry) from University of Pune, India in June 2000. Dissertation work for Master’s program involved Microwave assisted Oxidation of alcohols in the absence of solvents., under Guidance of Prof.G.M.Nazuruddin-University of Pune.. Bachelor of Science (Chemistry) from Shivaji University Kolhapur, India in 1998. CORE COMPETENCIES 2 years teaching experience to the B.Sc and M.Sc courses +6.2 years research experience in chemistry R&D . 5 years experience in record &operations of NMR instrument.2 years experience of HPLC & GCMS operations. Synthesizing, isolating & purifying the organic/bioorganic compounds by a wide range of modern synthetic organic chemistry methods and their characterization using spectroscopic techniques [UV, FT-IR, NMR, Polarimetry, GC, GC-MS, LC-MS, and HPLC]. Process development of Acrivastine impurities and process development of monomers (building blocks).Process development of chemical hybridizing reagents. Experienced in purification/characterization of complex carbohydrates (gangliosides) . Setting up, calibrating, operating and maintaining a variety of laboratory research equipment as specified by the requirements of the research study. Instruments can operate (Analytical) HPLC- , NMR , LCMS-, GC-MS, IR , UV-Visible . PROFESSIONAL EXPERIENCE Since August 2012 To till the date Government of Maharashtras,Institute of forensic science., Mumbai Joined as Assistant Professor(forensic chemistry department ) on contract Teaching field: Organic Chemistry a, Practical organic chemistry, Analytical chemistry Practical Chemistry: M.Sc Chemistry and B.Sc Chemistry (Analytical methods ) Since May 2006 To July 2012 GlaxoSmithKline Pharmaceuticals Ltd., Mumbai As Assistant Manager(chemistry R&D) Synthesis of monomers(building blocks) for process of drug design. Instrumental in carrying out the planning & conducting multi-step experiments after relevant literature survey. Running & maintenance of analytical instruments (NMR, LC-MS). Carried out the additional responsibility of observing EHS norms as a committee member. Pivotal in carrying out the multi-step synthesis of medium sized heterocyclic precursors and their characterization by using various spectroscopic techniques. Literature survey using SciFinder & other online sources has been a core activity for every project. Led & managed the Array projects (Combinatorial Chemistry). Introduced combinatorial chemistry concepts and streamlined various stages (design, manipulations, Characterization, data management, data transfer & dispatch) of an Array Project. Have dispatched & registered more than 1200 molecules into GSK compound collection since inception. June’2001-Nov 2002 Research Assistant with National Chemical Laboratory (NCL) Pune ,India in Organic Chemistry: Technology division As a Project assistant in Laboratory(NCL) Pune , India. a Organic chemistry: Technology division of “National Chemical I was involved in collaborating with a team of scientists to develop a synthetic process for synthesis of chemical hybridizing reagents sponsored by , Indian council of agricultural research-ICAR ,New Delhi. AWARDS AND FELLOWSHIPS, etc. Three years doctoral research fellowship award for International students from University of Milan ,Italy, for pursuing doctoral research (Nov2002-Dec2006). Silver reorganization award from GlaxoSmithKline Pharmaceuticals Ltd.Uk for 5 years GSK R&D Research.(July 2011) RECENT PUBLICATIONS Synthesis of Novel anologs 3,4- DIHYDRO-1H-QUINOLIN-2-ONE DERIVATIVES as typical antidepressant, seductive and anti-parkinson agents.- Nandini R. Pai , Deeptaunshu volume 2:(1),2012,117-128. Pusalkar , Dileep Khandekar , Hetrocyclic letters, Microwave promoted solvent-free Biginelli reaction for one pot synthesis of Dihydropyrimidin-2-(1H)-ones catalyzed by sulfamic acid: A green chemistry approach-Nandini pai ,Dileep Khandekar and Krishnakant Waghmode. Asian Journal of chemistry, volume 23,No.-12(2011)5217-5219 . Preparation of Schiff base Zinc Metal complex(DMAPIMP)2Zn and development of HPLC chromatographic method for its analysis.- Ramesh Yamgar, Dileep Khandekar and Sudhir Sawant. J. Chem. Pharm. Res., 2011, 3(1):188 An efficient synthesis of Rabeprazole sodium. Ramesh yamgar, Dileep Khandekar, Sudhir Sawant ,Asian Journal of Pharmacutical research [AJPRes] Vol 1,Issue 1,pg.13-16,March 2011. Synthesis of Novel Halo-Schiff Bases of 2-chloro-3-formylquinoline and Development of HPLC Chromatographic Method for it’s analysis. B. R. Thorata, Prasad Kamat, Dileep Khandekar, R. Yamgar, J. Chem. Pharm. Res.,(Accepted paper Dec 2011) 'Synthesis and Fluorescence properties of Schiff Bases of 2-chloro-3-formylquinoline' Journal of pharm. And Tech.(5)3,March 2012, 369-375. 'Synthesis and Fluoroscence properties of Schiff Bases of 4-hydroxy-3-methoxy-5-nitrobenzaldehyde' Prasad Kamat, Dileep Khandekar, Bapu Thorat, Ramesh Yamgar J. Chem. Pharm. Res., 2011, 3(6):1045-1054 RECENT PRESENTATIONS Synthesis of novel 3-chloro-N-{[7-methoxy-2-(4-methoxyphenyl)-1-Benzofuran-5-yl]Methyl}Aniline and its HPLC development, Bapu Thorat,Prasad Kamat, Dileep Khandekar and Ramesh Yamgar presented at ‘National Conference on Advance materials in Industries. (ISBN-978-81-920431-1-1-1)’ Feb. 10-11, 2012, Government of Maharashtra’s I.Y.College Jogeshwari (E), Mumbai, India Synthesis of novel 4-[(E)-Hydrazinylidenemethyl]-2-Methoxy-6-Nitrophenol derivatives., Bapu Thorat,Ram Jadhav Dileep Khandekar and Ramesh Yamgar presented at ‘National Conference on Advance materials in Industries. (ISBN-978-81-920431-1-1-1)’ Feb. 10-11, 2012, Government of Maharashtra’s I.Y.College Jogeshwari (E), Mumbai, India. Synthesis and Fluorescence properties of 3-{(E)-[Phenylimino]Methyl}Quinolin-2-ol and its Ni(II),Cu(II),Zn(II) and La(III) complexes. Bapu Thorat, Swati Lele, Dileep Khandekar and Ramesh Yamgar presented at ‘National Conference on Advance materials in Industries. (ISBN-978-81-920431-1-1-1)’ Feb. 10-11, 2012, Government of Maharashtra’s I.Y.College Jogeshwari (E), Mumbai, India. Synthesis of N-(1-Benzofuran-2-yl Methyl)-chloroaniline, Bapu Thorat, Dileep Khandekar Vaishali Acharya and Ramesh Yamgar presented at ‘National Conference on Advance materials in Industries. (ISBN-978-81-920431-11-1)’ Feb. 10-11, 2012, Government of Maharashtra’s I.Y.College Jogeshwari (E), Mumbai, India. TRAININGS Attended workshop on Applications in Bioinformatics sponsored by DBT , Government Of India.(feb2013) Attending training on a HPLC instrument operations sponsored by Shimatzu Ltd. (Oct 2012) Six weeks training module in Combinatorial Chemistry (Array chemistry) at GSK Thane India.(june 2008) Attended workshop on Polymer chemistry and Technology Sponsored by NCL Pune in June 2000. Attended Winning Attitude for Successful Professional (WASP) workshop by Sanjay Salooja conducted by GSK. Organized successfully workshop “Fundamentals and operations of Advanced analytical instruments” –major role was organizing secretary.(13-15 Feb 2013 )(Government of Maharashtra’s Institute of forensic science , Mumbai) PERSONAL DETAILS Date of Birth Religion Address References: : : : 14th June, 1976 Hindu. Matruchaya Building, Flat No-02 , Shivainagar ,Thane-400606 ,Cell-9773875074