GENERAL BIOLOGY I - BIOL 1406 Fall 2015, Instructor: Terry Johnson, Office: 441F Science Bldg, Phone: 254-968-9687 Email: tjohnson@tarleton.edu Office Hours: Mon.-Thurs. 9:30am-11:00am, or by appt. Course Description: Fundamental principles of living organisms will be studied, including physical and chemical properties of life, organization, function, evolutionary adaptation, and classification. Concepts of cytology, reproduction, genetics, and scientific reasoning are included. Learning Outcomes Upon successful completion of this course, students will: 1. Describe the characteristics of life. 2. Explain the methods of inquiry used by scientists. 3. Identify the basic requirements of life and the properties of the major molecules needed for life. 4. Compare and contrast the structures, reproduction, and characteristics of viruses, prokaryotic cells, and eukaryotic cells. 5. Describe the structure of cell membranes and the movement of molecules across a membrane. 6. Identify the substrates, products, and important chemical pathways in metabolism. 7. Identify the principles of inheritance and solve classical genetic problems. 8. Identify the chemical structures, synthesis, and regulation of nucleic acids and proteins. 9. Describe the unity and diversity of life and the evidence for evolution through natural selection. REQUIRED FOR COURSE: Internet access: for Blackboard, e-Text, etc. Computer labs with internet access are located on campus. Blackboard Mobile Learn is a free app for iOS or Android device. Clicker: by Turning Technologies (Support: 1-866-746-3015): You need ONE of the following Models: ResponseCard NXT, P/N RCXR-03 OR QT, P/N RCQR-01 Sources for clickers: Campus Bookstore OR online at http://store.turningtechnologies.com/ School Code-TSU4 If you order online, I highly recommend choosing 2-day shipping, so that your clicker will arrive in time for the first class assessment. All students must purchase a clicker and bring it to every class. Clickers will be required for taking assessments, exams, and for participating in other classroom activities. If you show up to class without your clicker, you are encouraged to remain in class and learn, but you will not be able to participate in submitting answers through the clicker system, which will negatively affect your grade. Clicker Registration: Click on this link in Blackboard to register your “ResponseCard Device ID”; use the 6-character Device ID on the back of your clicker (example: B12A3D). Failure to accurately register your clicker, and/or failure to use the clicker you are registered for in Blackboard during class, will prevent submission of your answers in class and result in a grade of Zero for Assessments/Exams. Principles of Biology e-Text: by Dynamic Books, 2015. ISBN: 978-1-942310-72-3 To purchase, you may order directly online from publisher (use Principles of Biology weblink in Blackboard), OR purchase an access card from Bookstore, and then register in Blackboard. Click on the Principles of Biology weblink in Blackboard to register and access. Click on “Student Registration Instructions” link in BB for more info. (There is NO enrollment key for this class.) Principles of Biology uses Chrome or Safari Internet browsers; it is not supported on Firefox. Laboratory Manual: BIOL 1406 (Hayden-McNeil/Tarleton State Univ, 2015) Financial Assistance: If you need assistance with purchasing a clicker or other materials, you may contact the Financial Aid office. Short-term loans may be available. No excuses will be accepted, including financial reasons, for not purchasing required materials. OPTIONAL MATERIALS: Other supplements may be available from the textbook publisher, but are not required for this course. Grades: Posted in Blackboard. Letter grades correspond to your average score as follows: A = 90 – 100; B = 80 – 89; C = 70 – 79; D = 60 – 69; F = 0 – 59 Your overall final grade in this course is a combination of your grades in lecture and lab, as follows: * 15% = The Average of all Assessments (lowest 3 Assessment grades dropped) * 35% = 3 Lecture Exams * 25% = Lab * 25% = Comprehensive Final Exam [Required, NO MAKEUP for the Final Exam (no exceptions)!] Assessments: Assessments will be given throughout the course, both outside of class and during each class period. Assessments will consist of timed questions over the topic listed for each date in the schedule. For Assessments in class, you must submit your Assessment answers in class using your clicker. If you do not bring your clicker to class, you will receive a Zero for the Assessment. Outside of class, Assessment answers must be submitted online through the e-Text. All assessments must be submitted electronically as required. NO LATE Assessments will be accepted. There are NO MAKEUPS for missed Assessments. NO EXCEPTIONS OR EXCUSES! However, the lowest 3 “in-class” Assessment grades will be dropped. Homework: Consists of reading the text chapters, reviewing, becoming familiar with all learning material for each upcoming class PRIOR to class, and submitting all e-Text “outside-of-class assessments” electronically by the due dates/times. Lecture notes and learning material will be provided for you on Blackboard in advance. Preparing before class will help you understand the class lecture better and perform well on the in-class Assessments. You are also encouraged to re-write the lecture notes given in Blackboard to help you learn. NOTE: Make sure you allow time to complete and submit all e-Text assessments electronically before the due dates/times. This may require you to complete e-Text assessments while on campus, to ensure that working computer hardware and internet access is available. NO LATE ASSESSMENTS WILL BE ACCEPTED FOR ANY REASON! Disability Accommodations: It is the policy of Tarleton State University to comply with the Americans with Disabilities Act and other applicable laws. If you are a student with a disability seeking accommodations for this course, please contact the Center for Access and Academic Testing, at 254.968.9400 or caat@tarleton.edu. The office is located in Math 201. More information can be found at www.tarleton.edu/caat, in the University Catalog, or at www.ada.gov. Attendance and Classroom Policies: 1) Attendance and punctuality is required. Missing or being late to class may negatively affect your grade. I will drop your 3 lowest “in-class” Assessment grades, but no more, regardless of excuse for any absences. So save these 3 “free” absences for real unexpected emergencies! 2) Please remain attentive and quiet unless given permission to speak. Talking during class is both rude and distractive to the instructor AND to the students around you. 3) All electronic devices should only be used for class purposes, or otherwise turned off and out of sight. 4) You must bring your clicker with batteries installed, two extra spare AAA batteries, paper & pencil, chapter notes (you are also encouraged to bring additional resources such as a laptop or other electronic device for web access, etc.) to every class, and participate in all classroom activities as instructed. It is VERY IMPORTANT that you bring your clicker and plenty of batteries to EVERY class, including Exam days! 5) If you must leave class early, inform the instructor before class begins. 6) You must take regularly scheduled exams on the same date/time as they are scheduled for your registered class time. *Anyone in violation of classroom policies may lose points for lack of participation, have points deducted from final course average, and/or be dismissed from the course with a grade of "F". Announcements: Will be made in Blackboard or in class. Check your Blackboard & Email every day! Lecture Exam Make-ups: Except for the Final Exam for which there is NO makeup, if you miss a Lecture Exam or arrive late on an Exam day, you may only make up any Lecture Exam(s) you miss for a University authorized absence or tardy. All make-up exams must be scheduled with the instructor within 72 hours of missing the exam, and may be given at a date/time near the end of the session or semester. Pursuant to the University Catalog, you are responsible for providing evidence to substantiate the reason for any absence or tardy. Evidence of a University authorized absence or tardy will be required and authenticated prior to my authorizing a make-up exam. Make-up exams are normally more difficult than regular exams and may be in essay format, so be prepared to write! It is highly recommended that you avoid missing, or arriving late, to any regularly scheduled exams. Academic Honesty: Tarleton State University expects its students to maintain high standards of personal and scholarly conduct. Students guilty of academic dishonesty are subject to disciplinary action. Academic dishonesty includes, but is not limited to, cheating on an exam or other academic work, plagiarism (submitting another person’s materials or ideas as one’s own), collusion (a secret understanding between two or more persons to gain something illegally), doing work for another person who will receive academic credit, the use of unauthorized books, notebooks, or other sources in order to secure or give help during an examination, the unauthorized copying of examinations, assignments, reports, or term papers, and the abuse of resource materials. The faculty member is responsible for initiating action for each case of academic dishonesty that occurs in his/her class. Disciplinary action may be taken beyond the academic discipline administered by the faculty member who teaches the course in which the cheating took place. Cheating can get you dismissed from the university, and is definitely not worth the chance! *Any student in class who is caught with more than one clicker in his/her possession will be removed from the class, receive an “F” for the course, and will be reported to Academic Affairs! Tentative Lecture/Exam Schedule: Aug 24 - Class orientation/Syllabus Unit 1: Introduction Aug 24 - Module 1: Evolution and Life on Earth Evolution is the core theme of biology. Aug 26 - Module 2: Energy and Matter Organisms interact with their environment, exchanging energy and matter. Aug 26 - Module 3: Practicing Biology Biological scientists use a process of inquiry that has developed over centuries and involves the collaboration of a global community. Unit 2: Chemistry Aug 31 - Module 4: Atoms, Elements, and Matter The properties of elements that form organic matter depend on the properties of atoms. Aug 31 - Module 5: Structure of Molecules and Compounds Complex carbon-based molecules form the basis for life on Earth. Aug 31 - Module 6: Water Water molecules have life-sustaining properties. Aug 31 - Module 7: Aqueous Solutions, Acids, and Bases The chemistry of acids and bases happens in aqueous solutions. Sep 2 - Module 8: Carbohydrates The properties and functions of carbohydrates are related to their molecular structures. Sep 2 - Module 9: Lipids Lipids are a diverse group of hydrophobic molecules that serve a variety of important biological functions. Sep 2 - Module 10: Proteins Proteins are a diverse group of polymers that play a critical role in nearly all cell functions. Sep 2 - Module 11: Enzymes Enzymes catalyze metabolic reactions that are crucial for life. Sep 2 - Module 12: Nucleic Acids The structure of nucleic acid molecules allows for the coding and transmission of information. Unit 3: Cells Sep 9 - Module 13: Cells (and comparing prokaryotic and eukaryotic) Cells are the basic unit of life. Sep 9/14 - Module 14: Eukaryotic Cells Eukaryotic cells contain membrane-enclosed organelles that play a pivotal role in their structure and function. Sep 14 - Module 15: Cytoskeleton The cytoskeleton contains proteins that maintain the cell’s shape and help with movement. Sep 14 - Module 16: Extracellular Structures Cells in a multicellular organism use extracellular structures for support and communication. Sep 16 – Exam 1: Modules 1-16 Module 17: Cell Membranes The plasma membrane surrounds the cell, protects it and helps it respond to the external environment. Sep 16/21 - Module 18: Membrane Transport Proteins regulate transport across the membrane. Sep 21 - Module 19: Exocytosis and Endocytosis The processes of exocytosis and endocytosis move large substances across the plasma membrane. Sep 21 - Module 20: Cell Signaling Cells use signaling molecules and receptors to communicate. Sep 21 - Module 21: Signal Transduction A cascade of events within a cell translates signals into cellular responses. Sep 21 - Module 22: Metabolism Organisms continually transform energy through metabolic processes. Sep 21 - Module 23: ATP and Cellular Work ATP provides the energy that powers cells. Sep 21 - Module 24: Biological Energy Transfer Cellular respiration involves the stepwise transfer of energy and electrons. Sep 23 - Module 25: Cellular Respiration I: Digestion and Glycolysis Harvesting energy in many cells begins with the breakdown of glucose into pyruvate during glycolysis. Sep 23/28 - Module 26: Cellular Respiration II: The Citric Acid Cycle and Oxidative Phosphorylation Pyruvate decarboxylation, the citric acid cycle, and oxidative phosphorylation. Sep 28 - Module 27: Fermentation and Anaerobic Respiration Organisms have methods for obtaining energy from fuel without the use of oxygen. Sep 30 - Module 28: Photosynthesis Overview Photosynthesis is one of the most important biological processes on Earth. Sep 30 - Module 29: Photosynthesis I: Absorbing and Capturing Light Energy Specialized plant pigments capture light for photosynthesis. Oct 5 - Module 30: Photosynthesis II: Energy and Sugars Photosynthesis involves biochemical pathways that use solar energy to build sugars from CO2 molecules. Oct 5 - Module 31: C3, C4, and CAM Photosynthesis C4 and CAM photosynthesis are more efficient photosynthetic pathways when water is limited. Oct 7 - Module 32: Cell Division Cells have processes for copying and distributing genetic material to daughter cells during division. Oct 7 - Module 33: Cell Cycle Control Molecular controls monitor the progression of the cell cycle. Oct 7 - Module 34: Apoptosis Programmed cell death is vital to the health and development of multicellular organisms. Unit 4: Genetics Oct 12 - Module 35: Inheritance in the Sexual Life Cycle The sexual life cycle contains phases with a full complement of chromosomes and with half of that number of chromosomes. Oct 12 - Module 36: Meiosis and Sexual Reproduction Meiosis makes sexual reproduction possible because it produces cells with half the number of chromosomes as the parental cell. Oct 14 – Exam 2: Modules 17-36 Oct 14/19 - Module 37: Mendel's Principles Mendel's experimental setup and data analysis laid the groundwork for the modern field of genetics. Oct 19 - Module 38: Mendelian Inheritance Inheritance follows the rules of probability. Oct 19 - Module 39: Non-Mendelian Inheritance Many patterns of inheritance are more complex than those Gregor Mendel described. Oct 21 - Module 40: Genetic Inheritance in Humans Human traits rarely follow strict Mendelian inheritance patterns. Oct 21 - Module 41: Chromosome Theory Thomas Hunt Morgan's discoveries helped solidify the chromosomal theory of inheritance. Oct 21 - Module 42: Linked Genes Linked genes are inherited in patterns that deviate from typical Mendelian inheritance. Oct 21 - Module 43: Genetic Disorders Inheritance of gene mutations or alterations in chromosomes may cause genetic disorders in humans. Oct 26 - Module 44: DNA Many scientists and technological advances contributed to the discovery of DNA structure and function. Oct 26 - Module 45: DNA Replication During DNA replication, a cell uses a variety of proteins to create a new copy of its genome. Oct 26 - Module 46: Mutations Changes in DNA have multiple causes and varied effects. Oct 26 - Module 47: Chromosomes Chromosome structure has multiple layers of organization that emerge from interactions between DNA and proteins. Oct 26 - Module 48: Gene Expression More than just transcription and translation, gene expression also involves epigenetic and environmental factors. Oct 28 - Module 49: Transcription Transcription is the process of copying information from DNA to RNA. Oct 28 - Module 50: Translation Translation is the process by which a cell assembles proteins from the genetic code. Nov 2 - Module 51: Prokaryotic Gene Regulation Prokaryotic gene regulation mechanisms allow bacteria to quickly adapt to their environments. Nov 2 - Module 52: Eukaryotic Gene Regulation Gene regulation in eukaryotic cells may occur before or during transcription or translation or after protein synthesis. Nov 2 - Module 53: Non-coding RNA Genomes give rise to non-coding RNA molecules that regulate gene expression. Nov 2 - Module 54: Cell Differentiation The many cell types in a multicellular organism emerge from a single cell by the process of differentiation. Nov 4 - Module 55: Cancer Modern scientific research illuminates our understanding of cancer genetics and continually revises our approach to cancer therapies. Nov 4 - Module 56: Viruses Viruses, which are non-cellular entities containing genetic material, rely on cellular hosts to replicate. OMIT - Module 57: Cloning DNA Scientists use viruses and bacteria and the enzymes they produce as tools for cloning DNA sequences from many different species. OMIT - Module 58: DNA Technology Researchers use DNA technology to sequence genes and study their expression, function, and relationship to disease. OMIT - Module 59: Cloning Organisms Cloning entire organisms may have applications ranging from stem cell production to conservation. OMIT - Module 60: Practical Applications of DNA Technology DNA technology has a variety of applications in many fields, including agriculture, medicine, and forensics. OMIT - Module 61: Genomics Accessing the information locked in an organism's genome has countless applications, from evolutionary comparisons to individualized medicine. OMIT - Module 62: Genome Diversity Genomes come in different sizes with widely varying numbers of genes and gene densities. Nov 9 – Exam 3: Modules 37-56 Unit 5: Evolution Nov 11 - Module 63: Introduction to Evolution Evolution is a cornerstone of biology that is supported by a vast amount of evidence from several fields of study. Nov 11 - Module 64: The Darwinian Revolution Charles Darwin's ideas formed the foundation for the modern theory of evolution. Nov 11 - Module 65: Forces That Drive Evolution Evolution results from a combination of selective forces and random events in the genome and the environment. Nov 16 - Module 66: Genetic Variation in Populations The driving forces of evolution affect the genetic makeup of individuals in populations. Nov 16 - Module 67: Calculating Changes in Allele Frequencies The Hardy-Weinberg equation serves as a baseline to understand changes in allele frequencies due to evolutionary processes. Nov 16 - Module 68: Effects of Natural Selection Changes in allele frequency can occur in a population over successive generations when variations in heritable traits cause differences in reproductive success. Nov 18 - Module 69: Interactions in Evolution Adaptations arise as a result of interactions between organisms and their environment. Nov 18 - Module 70: The Biological Species Concept According to the biological species concept, reproductive isolation drives the evolution of new species. Nov 23 - Module 71: Geographic Factors in Speciation Geography plays an important role in the evolution of new species. Nov 23 - Module 72: Pace of Speciation The pace of speciation depends on interactions between a population’s genome and its environment. Nov 30 - Module 73: Origin of Life Life on Earth likely began as macromolecules that developed into self-replicating protocells. Nov 30 - Module 74: Early Evolution of Life Major events in early life include the evolution of prokaryotes, photosynthesis, eukaryotes, multicellularity, and the colonization of land. Dec 2 - Module 75: Change in Species over Geologic Time The assemblage of species inhabiting Earth changes over geologic time. Dec 4, 3:00pm-5:30pm, Room 102 – Final Exam (Comprehensive-NO MAKEUPS!!!) How to succeed in this course: 1. Avoid “cramming” at the last minute; pace yourself, manage your time, and make a regular daily schedule for study time. 2. Expect to spend a minimum of 2 hours of good solid quality study time for every hour you are in class. This is the general “rule of thumb” for college. 3. Break the material up into smaller sections, and focus on one section at a time. 4. Take short breaks between 15-20 minute study sessions. 5. Get plenty of sleep (but not during class ) and eat healthy. 6. Find good, productive study partners. Drill each other. Ask each other questions from the notes and material. 7. Re-copy or rewrite the notes in your own words to help you organize and remember. 8. Use all the resources made available to you, including illustrations, Youtubes, etc., on the web. 9. Get away from and turn off distractions during study sessions, especially electronics, Facebook, etc. (no place like the library!) 10. Understand that the more you repeat the notes and spend time with the material, the more it is going to sink in. 11. Don’t miss classes or labs! 12. Be confident in your ability to learn this stuff! 13. More help at: http://www.tarleton.edu/successweb/ssp/index.html http://www.tarleton.edu/ssp/programs/studyskills.html You may also contact the Center for Academic Readiness and Success for any information on additional tutoring. Academic Affairs Core Value Statements Academic Integrity Statement Tarleton State University's core values are integrity, leadership, tradition, civility, excellence, and service. Central to these values is integrity, which is maintaining a high standard of personal and scholarly conduct. Academic integrity represents the choice to uphold ethical responsibility for one’s learning within the academic community, regardless of audience or situation. Academic Civility Statement Students are expected to interact with professors and peers in a respectful manner that enhances the learning environment. Professors may require a student who deviates from this expectation to leave the face-to-face (or virtual) classroom learning environment for that particular class session (and potentially subsequent class sessions) for a specific amount of time. In addition, the professor might consider the university disciplinary process (for Academic Affairs/Student Life) for egregious or continued disruptive behavior. Academic Excellence Statement Tarleton holds high expectations for students to assume responsibility for their own individual learning. Students are also expected to achieve academic excellence by: • honoring Tarleton’s core values. • upholding high standards of habit and behavior. • maintaining excellence through class attendance and punctuality. • preparing for active participation in all learning experiences. • putting forth their best individual effort. • continually improving as independent learners. • engaging in extracurricular opportunities that encourage personal and academic growth. • reflecting critically upon feedback and applying these lessons to meet future challenges. Academic Affairs Service statement Tarleton faculty, staff, and students are expected to model responsible citizenship through service activities that promote personal and academic growth while enhancing the university, local, regional, national, and global communities. These activities will foster a culture of academic/public engagement that contributes to the achievement of the university’s mission and core values.