13th Saratov Fall Meeting 2013
23-28 September 2013, Saratov, Russia
Functional principle of explosive autonomous movable nanorockets
controlled by focused laser
Johannes Frueh 1*, Zhiguang Wu1, Qiang He1
1
Key Laboratory of Microsystems and Microstructures Manufacturing, Ministry of Education,
Micro/Nano Technology Research Centre, Harbin Institute of Technology, Yikuang Street 2,
Harbin 150080, China; Email: johannes.frueh@hit.edu.cn, Tel ： +86-451-86403605；Fax ：
+86-451-86403605 * johannes.frueh@hit.edu.cn
Polyelectrolyte Multilayer thin films (PEM) produced by layer-by-layer dipping[1] approach
have been produced in many shapes including capsules and tubes[2,3]. These capsules and tubes
can perform autonomous motion and can be used for drug delivery, with a controlled release
mechanisms based on laser opening[4], pH, ultrasound or other effects[5]. In this talk, a new
model of PEM based molecular motor with an additional functionality is presented. The
presented molecular motor is not only able to do controlled and autonomous motion, and to
deliver drugs, it is also able to destroy surrounding cells with its controlled and triggerable
explosion. The energy for the explosion as well as for the controlled motion is delivered by an IR
laser beam. The used IR color agend are gold nanoparticles.
Literature:
[1]
Decher G, Hong J D and Schmitt J 1992 Build up of ultrathin multilayer films by a self-assembly
process:III. Consecutively alternating adsorption of anionic and cationic polyelectrolytes on charged
surfaces Thin Solid Films 210-211 831–5
[2]
Caruso F, Caruso R A and Moehwald H 1998 Nanoengineering of Inorganic and Hybrid Hollow Spheres
by Colloidal Templating Science 282 1111–4
[3]
Wu Z, Wu Y, He W, Lin X, Sun J and He Q 2013 Self-Propelled Polymer-Based Multilayer Nanorockets
for Transportation and Drug Release Angewandte Chemie n/a–n/a
[4]
Gorin D A, Portnov S A, Inozemtseva O A, Luklinska Z, Yashchenok A M, Pavlov A M, Skirtach A G,
Möhwald H and Sukhorukov G B 2008 Magnetic/gold nanoparticle functionalized biocompatible
microcapsules with sensitivity to laser irradiation. PCCP 10 6899–905
[5]
Decher G and Schlenoff J 2012 Multilayer Thin Films: Sequential Assembly of Nanocomposite Materials ed
G Decher and J Schlenoff (Weinheim: Wiley-VCH Verlag GmbH & Co. KGaA)
H2O+O2
H2O2
Tube explodes
O2
PEM tube
IR-laser
PEM tube
Fig. 1: Reaction scheme for the controlled self explosion
Acknowledgements: This work was supported by the National Nature Science Foundation of China
(91027045), 100-talent Program of HIT, China Postdoctoral Science Foundation (2013M531019) and
New Century Excellent Talent Program (NCET-11-0800), Harbin Institute of Technology.
1