Some Chemical Hazards in Foods and the Illnesses they Cause Hazard Symptoms/outcome Source/Cause Food allergens and intolerances Peanut allergy Soybean allergy Milk allergy Milk (lactose) intolerance Egg allergy Shellfish allergy Flushed face, hives, swollen or itchy lips, mouth, eyes, or tongue; tightness in mouth, chest or throat.; difficulty breathing or swallowing, drooling, wheezing, choking, coughing; running nose, voice change; vomiting, nausea, diarrhea, stomach pains; dizziness, unsteadiness, sudden fatigue, rapid heartbeat, chills; pallor, loss of consciousness, coma, death. Peanut allergy is responsible for more fatalities than any other type of allergy Acne and other skin conditions, like eczema, Swelling, Nasal congestion, Anaphylaxis, Asthma, Canker sores or fever blisters, Colitis and other gastrointestinal problems, including diarrhea, Conjunctivitis, Shortness of breath, Fever, fatigue, weakness, and nausea, Low blood pressure, Itching, Hay fever, Hives Skin reactions may include an itchy red rash, hives, eczema, allergic "shiners" (black eyes), and swelling of lips, mouth, tongue, face or throat. Digestive system reactions might include nausea, vomiting, diarrhea, gas, bloating, or abdominal cramps. Respiratory system reactions include runny nose, sneezing, watery eyes, itchy eyes, nasal congestion, wheezing, shortness of breath, or coughing; or even anaphylactic shock. Cramps, bloating, gas, diarrhea, and nausea. Not as serious as true allergy. Peanuts, Peanut butter, Cold pressed peanut oil, Peanut flour, baked goods containing peanut products Asthma, dermatitis, hay fever, diarrhea, gastrointestinal symptoms, hives, nausea, swelling of lips and mouth, vomiting, wheezing, and in some cases, anaphylaxis. Skin, stomach, or respiratory problems. More specifically they can include nasal congestion, hives, itching, swelling, wheezing or shortness of breath, nausea, upset stomach, cramps, heart burn, gas, diarrhea, lightheadedness, or fainting. Eggs, Egg whites, Egg yolks, Dried eggs or egg powder, Egg solids, Lysozyme (used in cheese manufacture), Foods containing eggs including ice cream, pasta, breadings. Abalone, Clams, Crab, Crayfish, Lobster, Oysters, Scallops, Shrimp, Cockle, Sea urchin, Mussels Soy flour, Soy fruits, Soy nuts, Soy milk, Soy sauce, Soy sprouts, Soybean granules or curds, possibly soy oil or lecithin Milk and milk solids; Non-fat, skim milk, or powdered milk; Buttermilk; Evaporated milk; Yogurt; Cream, cream cheese, sour cream; Cheese, cheese powder, cottage cheese, curds; Whey and whey products; Butter, butter fat Same as for milk allergy Hazard Tree nut allergy Wheat gluten allergy and intolerance Symptoms/outcome Source/Cause Hives or blotching around the mouth which may spread to the rest of the body, immediate runny nose, sneezing and itchy water eyes, coughing, choking or gagging, wheezing and trouble breathing, and cramps, vomiting and diarrhea. The allergic reaction can stop at any stage, or may progress to anaphylaxis and death Celiac disease, Celiac Sprue (allergenic), chronic diarrhea, with abdominal bloating, sometimes pain, weight loss, nutrient malabsorption Almonds, Brazil nuts, Cashews, Chestnuts, Filberts, Hazelnuts, Hickory nuts, Macadamia nuts, Pecans, Pine nuts, Pistachios, Walnuts, Foods containing nuts (ex. Confections, pesto, almond paste) Whole wheat or enriched flour, High gluten flour, High protein flour, Bran, Farina, Graham flour, Bulgur, Durum, Semolina, Wheat malt, Wheat starch (may be used in packaging aid), Modified starch Naturally occurring toxins Lectin or hemagglutinin (plant toxin) Ciguatera Fish Raw or undercooked kidney or white beans Gastrointestinal, neurological, and cardiovascular disorders. (tingling, burning, numbness, drowsiness, incoherent speech, and respiratory paralysis, death) Groupers, barracudas, snappers, jacks, mackerel, and triggerfish that have consumed certain toxic algaes. Paralytic Shellfish Poisoning, (nausea, vomiting, diarrhea, and abdominal pain accompanied by chills, headache, and fever) Pufferfish poisoning, Fugu Poisoning (tingling, burning, numbness, rapid death possible) Filter-feeding mollusks, particularly mussels, clams, cockles, oysters, and scallops. Gonads, liver, intestines, and skin of pufferfish or “fugu” fish. Aflatoxins Acute necrosis, cirrhosis, and carcinoma of the liver Fumonisins Associated with esophageal cancer in humans Toxic and mutagenic effects in animals. FDA believes that humans may be at risk of harm at some level of exposure to patulin Pre- and post-harvest growth of Aspergillus flavus and A. parasiticuscorn and corn products, peanuts and peanut products, cottonseed, milk, and tree nuts such as Brazil nuts, pecans, pistachio nuts, and walnuts. Pre-harvest growth of Fusarium verticillioides and F. proliferatum in corn. Apple juice and cider from apples infected with certain species of Penicillium, Aspergillus, and Byssochylamys. Primarily post-harvest. Poisoning (seafood toxin) Saxitoxin (seafood toxin) Tetrodotoxin, (seafood toxin) Mycotoxins Patulin Food additives and colorants Sulfites Asthma, chest tightness, nausea, hives, or even anaphylactic shock; primarily affects severe asthmatics Food colorants (FD&C Yellow #5) May cause hives in fewer than one out of 10,000 people Condiments, dried and glacéed fruit, jam, gravy, dehydrated or pre-cut or peeled "fresh" potatoes, molasses, shrimp, and soup mixes, beverages (such as beer, wine, hard cider, fruit and vegetable juices, and tea) Foods to which FD&C Yellow No. 5 has been added, including butter, cheese, and ice cream. Under federal law, the presence of (FD&C Yellow #5) must be indicated on the label. Hazard Flavors, preservatives Monosodium glutamate Symptoms/outcome Allergic-like reactions possible in susceptible individuals Headaches, palpitations, vomiting, nausea, dizziness, sweating, ringing in the ears to faintness. Often called the "Chinese restaurant syndrome” Source/Cause Foods containing additives Hydrolyzed vegetable protein (HVP), natural flavorings, hydrolyzed milk protein, autolyzed yeast, natural beef flavoring, kombu extract, bouillon, natural pork flavoring, barley malt, natural chicken flavoring, natural seasonings, textured protein, seasonings, malt extract, hydrolyzed oat flour, tamari, malt flavoring Toxic chemicals used in around processing facilities Cleaners and sanitizers Fuels, lubricants, oils Mild reaction to death. Safe when approved pesticides are used according to label direction. Mild reaction to death. Safe when approved pesticides are used according to label direction. Pesticides Nausea, vomiting, stomach cramps, diarrhea, headache, nervousness, blurred vision, chest pain, confusion and twitching. Convulsions and death at very high levels. Safe when approved pesticides are used according to label direction. Toxic metals (arsenic, antimony, cadmium, copper, lead, tin, zinc, mercury) Mouth burning, nausea, vomiting, stomach cramps, diarrhea, shock Contaminated food, safe when used according to label directions Spills on food or food-contact surfaces, indiscriminate or incorrect use in foodhandling facilities or equipment, contaminated food. Pesticide spills on food or food-contact surfaces, indiscriminate spraying of foodhandling facilities or equipment, improper storage of pesticides or improper container labeling, application at excessively high levels, premature harvest of food crops after pesticide application and incomplete washing of fruits and vegetables are all critical sources of pesticide poisoning. High-acid foods and drinks in contact with metal food contact surfaces, contaminated water. Toxic chemicals formed during processing Acrylamide Heterocyclic amines (HCAs) Trans fatty acids At high levels, toxicity to nervous system and potential genetic damage that may lead to cancer. Hazard in foods not confirmed. May pose human cancer risk Contributes to increased blood LDLcholesterol ("bad" cholesterol) levels Starchy foods such as French fries, potato chips, bread, rice, and processed cereals, cooked at high temperatures. Muscle meats such as beef, pork, fowl, and fish cooked at high temperatures. Partial hydrogenation of oils, butter.