22/01/10 AGENDA FOR ANNUAL REVIEW MEETING 2010 UNIVERSITY OF NAIROBI STD/AIDS COLLABORATIVE GROUP MAYFAIR COURT HOLIDAY INN, NAIROBI Monday, January 25, 2010 8:00 – 9:00 Registration 9:00 – 9:30 OPENING CEREMONIES Chair: Omu Anzala Opening remarks – Prof. I. Kibwage – Principal, College of Health Sciences, Univ. Nairobi Reflections on the 30th Anniversary of the Univ. Manitoba / Univ. Collaboration – Prof. F. Plummer – Public Health Agency of Canada / Univ. Manitoba Greetings from the University of Manitoba – Prof. D. Barnard – President, Univ. Manitoba Official opening – Prof. G. Magoha – Vice-Chancellor, Univ. Nairobi 9:30 – 9:40 Break Session I: Special Presentations Co-Chairs: Omu Anzala Joanne Embree 9:40 – 10:00 Unraveling the mysteries of HIV resistance -- progress to date (Frank Plummer – Public Health Agency of Canada / Univ. Manitoba) 10:00 – 10:20 The Thailand HIV Vaccine trial – what have we learned? Estimating the potential impact of an AIDS vaccine (Omu Anzala – KAVI / Univ. Nairobi) 10:20 – 10:40 The debate about the importance of concurrency as a driver of the epidemic (Martina Morris – Univ. Washington) 10:40- 11:00 Coffee / tea Session II: Epidemiology, Transmission, Risk Factors I Co-Chairs: Nelly Mugo Stephen Moses 11:00 – 11:15 Risk factors and potential intervention targets in HIV-1 discordant couples (Brandon Guthrie – Univ. Washington / Univ. Nairobi) 11:15 – 11:30 Status disclosure amongst HIV-infected adults at Kilifi District Hospital 2009 (Davies Kimanga – NASCOP / Jomo Kenyatta Univ. / Wellcome Trust / KEMRI) 11:30 – 11:45 Widow inheritance and HIV infection/transmission: where does the inheritor fit in the risk puzzle? (Kawango Agot, Jacob Odhiambo – Impact-RDO / Univ. Washington / Univ. Nairobi) 11:45- 12:00 Correlates of HIV infection among young adults in Kisumu 2007-2008 (Anne Gumbe – CDC / KEMRI) 12:00 – 12:15 Determining the best strategies to use to find persons at high risk of HIV infection for HIV prevention studies in Kisumu (Anne Adega – CDC / KEMRI) 12:15 – 12:30 A cross-sectional behavioural survey of male sex workers who have sex with men and women in Nairobi (Anna Seifried, Mary Gichuhi - Univ. Manitoba / Univ. Nairobi) 12:30 – 12:45 To be or not to be a sex worker: perception of female sex workers and non-sex workers regarding HIV prevention and contraceptive practices (Elizabeth Ngugi – Univ. Washington / Univ. Nairobi) 12:45- 1:00 The impact of family support on HIV prevention knowledge and practices by infected youth: The Tuungane Youth Project (Kawango Agot – Impact-RDO / CDC) 1:00 – 2:00 Lunch Session III: Interventions I – Male circumcision Co-Chairs: Jeckoniah Ndinya-Achola Robert Bailey 2:00 – 2:15 Male circumcision for HIV prevention in Nyanza: one year and counting (Kawango Agot, Walter Obiero - Impact-RDO / Nyanza Reproductive Health Soc. / CDC) 2:15 – 2:30 Male circumcision for HIV prevention in Nyanza: results and lessons from the rapid results initiative (RRI) (Walter Obiero, June Odoyo, Kawango Agot - Nyanza Reproductive Health Soc / Impact-RDO / CDC/ FHI) 2:30 – 2:40 Examining the capacity of the private sector health providers to support male circumcision scale-up in Kenya (Mwende Mbondo – Male Circumcision Consortium / FHI) 2:40 – 2:50 Assessing the effectiveness of male circumcision outreach services in Kenya (George Odingo – Male Circumcision Consortium / EngenderHealth) 2:50 – 3:00 Results of a baseline random household survey on male circumcision and HIV in Kisumu Municipality (Cosam Angwana – Univ. Illinois Chicago / Male Circumcision Consortium / Univ. Nairobi) 3:00 – 3:10 Voluntary Medical Male Circumcision: An Assessment of Adverse Events (Amy Herman-Roloff - Univ. Illinois Chicago / Male Circumcision Consortium / Univ. Nairobi) 3:10 – 3:20 Factors associated with the circumcision decision: baseline results from the risk compensation study in Nyanza Province (Nelli Westercamp – Univ. Illinois Chicago / Male Circumcision Consortium / Univ. Nairobi) 3:20 – 3:30 Pilot study of the Shang Ring: a novel male circumcision device for HIV prevention (Frederick Ndede – EngenderHealth / NASCOP / Cornell Univ.) 3:30 – 3:40 Discussion 3:40 – 4:00 Coffee / tea 4:00 – 5:30 SATELLITE SESSION – ROLLING OUT AND SCALING-UP OF MALE CIRCUMCISION SERVICES IN KENYA – ISSUES ARISING AND LESSONS BEING LEARNED (Conveners – Kawango Agot, June Odoyo) 6:00 – 9:00 RECEPTION – Holiday Inn Mayfair Court – co-hosted by Prof. G. Magoha, ViceChancellor, Univ. Nairobi and Dr. D. Barnard, President, Univ. Manitoba; all conference participants invited to attend Tuesday, January 26, 2010 Session IV: Interventions II Co-Chairs: Kishor Mandaliya Craig Cohen 8:30 – 8:50 Update on the Pre-Exposure Prophylaxis (PrEP) Clinical Trial: Parallel comparison of Tenofovir and Embricitabine/Tenofovir pre-exposure prophylaxis to prevent HIV-1 acquisition within HIV-1 discordant couples study Kenya and Uganda (Connie Celum – Univ. Washington / Univ. Nairobi) 8:50 – 9:05 Pre-exposure prophylaxis (PrEP) research: a quantitative ethics appraisal (Madzouka Kokolo – Univ. Ottawa) 9:05 – 9:25 Phase III multi-center double-blind randomised placebo-controlled effectiveness and safety study to assess the role of Truvada® in preventing HIV acquisition in women (Fred Owino, Kawango Agot – Impact-RDO /FHI) 9:25 – 9:40 Secondary HIV prevention: translation and transfer of evidence-based interventions (Ben Jarabi – Univ. Washington / New York Univ. / Univ. Nairobi) 9:40 – 9:55 HIV-infected males – a neglected lot? (John Mungai – Univ. Manitoba / Univ. Nairobi) 9:55 – 10:15 Evaluating the impact of a large-scale HIV prevention program in Karnataka, South India (Stephen Moses – Univ. Manitoba) 10:15 – 10:30 Rapid, large-scale mass HIV counselling and testing, malaria and diarrhoea prevention program in rural Kenya: report on the initial campaign (Alexandre Doyen – Vestergaard Frandsen / Kenya MOH / CHF) 10:30 – 11:00 Coffee / tea Session V: Bacterial and Viral STIs Co-Chairs: Carey Farquhar King Holmes 11:00 – 11:15 Prevalence, sensitivity of syndromic diagnosis and risk factors for sexually transmitted infections within a Kenyan HIV incidence cohort study (Fred Otieno – CDC / KEMRI) 11:15 – 11:30 High prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae infections among HIV-1 negative MSMs in Coastal Kenya (Eduard Sanders - Wellcome Trust / KEMRI) 11:30 - 11:45 Quinolone resistance to Neisseria gonorrhoeae in a cohort of young men in Kisumu 2002-2009 (Supriya Mehta – Univ. Illinois Chicago / Univ. Manitoba / Univ. Nairobi) 11:45 – 12:00 Factors associated with prevalent and incident HSV-2 in high-risk Kenyan men (Haile Okuku – Wellcome Trust / KEMRI) 12:00 – 12:15 HSV-2 incidence, GUD and HIV among circumcised and uncircumcised men in Kisumu (Robert Bailey – Univ. Illinois Chicago / Univ. Nairobi) 12:15 – 12:30 Relative HIV resistance in Kenyan sex workers is not due to an altered prevalence or mucosal immune impact of HSV-2 infection (H. Baltzer – Univ. Toronto / Univ. Manitoba / Univ. Nairobi) 12:30 – 12:45 Prevalence and correlates of cervical precancerous lesions among women in HIV-1 discordant couple relationships in Nairobi (Anne Rositch – Univ. Washington / Univ North Carolina / Univ. Nairobi) 12:45 – 1:00 Risk factors associated with colposcopy-detected penile lesions in Kenyan men (Danielle Backes – Univ. North Carolina / Univ. Illinois Chicago / Univ. Manitoba / Univ. Nairobi) 1:00 – 2:00 Lunch Session VI: Symposium on Zoonotic Diseases Co-Chairs: Benson Estambale Michael Drebot 2:00 – 2:15 Zoonotic diseases, the Kenyan experience (Rosemary Sang-KEMRI) 2:15 – 2:30 From outbreak responses to the development of preventative measures: Ebola and H1N1 experiences (Garry Kobinger- National Microbiology Laboratory, Public Health Agency of Canada / Univ. Manitoba) 2:30 – 2:45 Understanding Periodic Outbreaks of Rift Valley Fever Outbreaks in East Africa (Kariuki Njenga - CDC) 2:45 – 3:00 Diagnostic considerations for the identification and characterization of emerging or under recognized zoonotic pathogens (Michael Drebot – National Microbiology Laboratory, Public Health Agency of Canada / Univ. Manitoba) 3:00 – 3:15 Changes in livestock systems and their impact on zoonoses and how these are linked to a one health approach (John McDermott – International Livestock Research Institute ILRI). 3:15 – 3:30 Risk factors, disease transmission dynamics and predictive potential for early warning on zoonoses in East Africa. (Philip Nyaga – Univ. Nairobi) 3:30 – 3:45 Investigation of a mysterious disease outbreak in Western Kenya (Omu Anzala – Univ. Nairobi) 3:45 – 4:00 Coffee / tea 4:00 – 5:30 SATELLITE SESSION - CAPACITY BUILDING FOR THE UNIV. NAIROBI LEVEL 3 ENHANCED LABORATORY - training, service delivery, sustainability (Convener – Julius Oyugi) Wednesday, January 27, 2010 Session VII: Resistance and Susceptibility to HIV Infection and Disease Co-chairs: Keith Fowke Kristina Broliden 8:30 – 8:45 The role of mucosal immunology and protection against HIV transmission at the female genital tract (Blake Ball – Univ. Manitoba / Univ. Nairobi) 8:45 – 9:00 Setting up multiple barricades along the HIV infection pathway – learning from the genetic pathway profile of HIV-resistant sex workers (Ma Luo – Univ. Manitoba / Univ. Nairobi) 9:00 – 9:10 The difference in polyfunctional HIV-specific CD4 responses in HIV-1 exposed seronegative commercial (ESN) versus newly negative commercial sex workers (Marion W. Kiguoya– Univ. Manitoba / Univ. Nairobi) 9:10 – 9:20 Identifying specific HIV epitopes responsible for polyfunctional HIV-1 immune responses that could accord protective immunity in exposed seronegative commercial sex workers (James Mwanjewe – Univ. Manitoba / Univ. Nairobi) 9:20 – 9:35 HIV viral set point and T cell responses in individuals with naturally-induced virusspecific CD8+ T cell responses prior to HIV acquisition (Rupert Kaul – Univ. Toronto / Univ. Manitoba / Univ. Nairobi) 9:35 – 9:45 Characterisation of IL-17-secreting cervical CD4+ T cells in female sex workers (Lyle McKinnon – Univ. Toronto / Univ. Manitoba / Univ. Nairobi) 9:45 – 9:55 Abundant expression of HIV target cells and C-type lectin receptors in the foreskin tissue of young Kenyan men (Taha Hirbod – Karolinska Inst / Univ. Illinois Chicago / Univ. Manitoba / Univ. Nairobi) 9:55 – 10:05 Cervical vaginal environment and the epigenetic controls (Ruey-Chyi Su – Univ. Manitoba / Univ. Nairobi) 10:05 – 10:20 Increased levels of immune activation in the genital tract of healthy young women from sub-Saharan Africa (Craig Cohen – UCSF / KEMRI) 10:20 – 10:35 Does abstinence make the immune response grow fonder? Exploring the immunological effects of a break from regular sex work (Keith Fowke – Univ. Manitoba / Univ. Nairobi) 10:35 – 11:00 Coffee / tea Session VIII: Treatment and Care I Co-Chairs: Dorothy Mbori-Ngacha Elizabeth Bukusi 11:00 – 11:20 PEPFAR in 2009 – annual report (Lynn Adrian – CDC / KEMRI) 11:20 – 11:35 Longitudinal screening for peripheral neuropathy among patients initiating antiretroviral therapy in Mombasa (Aabid Ahmed - Bomu Medical Center / New York Univ.) 11:35 – 12:20 The HIV Neurology in Kenya (THINK) study: Utility of a diagnostic tool for HIV-associated cognitive impairment in Western Kenya: pilot testing (Judith Kwasa – UCSF / KEMRI) - Pattern of neuropsychological performance among HIV-positive patients in Kenya (Edwin Omondi – UCSF / KEMRI) - Utility of HIV-associated neuropathy screening tools in Western Kenya: pilot testing (Deanna Cettomai – UCSF / KEMRI) - Utility of quantitative sensory testing in characterising HIV-associated peripheral neuropathy in Western Kenya: pilot testing (Deanna Cettomai - UCSF / KEMRI) - Measuring antiretroviral adherence in HIV-infected individuals with and without cognitive impairment in Western Kenya: pilot testing (Judith Kwasa - UCSF / KEMRI) 12:20 – 12:35 Effect of antiretroviral therapy on liver and kidney parameters among HIV-infected women and their infants in Kisumu (Nicholas Polle – CDC / KEMRI) 12:35 - 12:50 Effects of post-election violence on Kenya’s HIV response and the potential emergence of HIV drug resistance (Irene Mukui – NASCOP) 12:50 – 1:00 Effect of gender of voice in responding to sensitive sexual behaviour questions using Audio Computer-Assisted Self-Interview (ACASI) in an HIV incidence cohort study in Kisumu (Isaiah Oloo – CDC / KEMRI) 1:00 – 2:00 Lunch Session IX: Interventions III Co-Chairs: James Kiarie Barbara Lohman-Payne 2:00 – 2:15 Free-listing and service mapping reveals gender differences in reproductive and sexual health service perceptions and access (Mercy Owuor – Univ. Washington / Univ. Nairobi) 2:15 – 2:30 Widow inheritance and sexual networks in Siaya District: developing culturallyappropriate interventions in the context of evolving traditions: baseline results (Kawango Agot, Rena Otieno - Impact-RDO / Univ. Illinois Chicago / Univ. Nairobi) 2:30 – 2:45 “She’s my sister-law, my visitor, my friend:” Experiences of home follow-up in HIV research and intervention in Western Kenya (Philister Madiega – CDC / KEMRI) 2:45 – 3:00 Spatial sampling using GPS for a community-enrolled prospective cohort study (Francis Njiri - Univ. Washington / Univ. Nairobi) 3:00 – 3:15 Barriers in the delivery of HIV and AIDS services to people with disabilities (Sarah Nduta – Liverpool VCT) 3:15 – 3:45 The HAART Cell Phone Adherence Study: Preliminary RCT results (Richard Lester – Univ. Manitoba / Univ. British Columbia / Univ. Nairobi) - Use of mobile phones for health care – a qualitative analysis (Sarah Karanja – Univ. Manitoba / Univ. Nairobi) Baseline measures of health-related quality of life (Paul Ritvo – York University / Univ. Manitoba / Univ. Nairobi) 3:45 – 4:00 Coffee / tea 4:00 – 5:30 SATELLITE MEETING – CELL PHONE STUDY END-OF-PROJECT REPORT – RESULTS, SCALE-UP ISSUES, FUTURE DIRECTIONS (Convener – Anna Seifried) Thursday, January 28, 2010 Session X: Perinatal transmission and HIV/AIDS in children Co-chairs: Ruth Nduati Lisa Avery 8:30 – 8:45 Update on the Kesho Bora Clinical Trial: Triple antiretroviral (ARV) prophylaxis during pregnancy and breastfeeding compared to short-ARV prophylaxis to prevent mother-tochild transmission of HIV-1 (M. Mwaura – ICRH / Univ. Ghent / Univ. Nairobi) 8:45 – 9:00 Infant and young child feeding in the context of HIV (Mildred Mudany – CDC / KEMRI) 9:00 – 9:15 Evaluation of response to treatment among women exposed to anti-retrovirals for prevention of mother-to-child HIV transmission: a follow-up of the Kisumu Breastfeeding Study (KiBS) (Frank Angira – CDC / KEMRI) 9:15 – 9:30 Antiretroviral treatment outcomes among HIV-infected infants exposed to maternal antiretroviral therapy for prevention of mother-to-child HIV transmission (Lilian Nafisa – CDC / KEMRI) 9:30 – 9:40 Audit of outcomes of HIV-infected children admitted to the paediatric wards at Kilifi District Hospital with early commencement of anti-retroviral therapy (Helen Nabwera – Wellcome Trust / KEMRI) 9:40 – 9:50 Characteristics of paediatric patients lost to follow-up in an HIV care and treatment clinic in Kisumu (C. Kidiga – FACES / KEMRI / UCSF) 9:50 – 10:00 Successful outcomes following decentralisation of tertiary paediatric HIV care to a community-based paediatric antiretroviral treatment network, Chiang Rai, Thailand (Abraham Katana – Oxford Univ. / CDC) 10:00 – 10:10 Long- term treatment outcomes and predictors of mortality in HIV-infected children in Northern Thailand 2002-2008 (Abraham Katana – Oxford Univ. / CDC) 10:10 – 10:20 Health system factors are more important than stigma in PMTCT interventions uptake (John Kinuthia – Univ. Washington / Univ. Nairobi) 10:20 – 10:30 Prevention of mother-to-child transmission of HIV-1: from unmet need to unused service – a new study in Nyanza (John Okanda – CDC / KEMRI / Univ. Washington) 10:35– 11:00 coffee / tea 11:00 – 11:15 HSV-2 suppression to reduce maternal HIV-1 RNA levels during pregnancy and breastfeeding: a randomised clinical trial (Alison Drake – Univ. Washington / Univ. Nairobi) 11:15 – 11:30 Is population-based HIV prevalence data able to accurately estimate the number of women needing PMTCT services? (Ruth Nduati – Univ. Nairobi) Session XI: Molecular epidemiology Co-Chairs: Walter Jaoko Blake Ball 11:30 – 11:45 Multidrug resistant HIV-1 and recombination between variants from the genital tract and plasma: a longitudinal analysis (Barbara Weiser - Wadsworth Center NY State Dept of Health, Albany Medical College) 11:45 – 12:00 Evolution and recombination of genes encoding HIV-1 drug resistance and tropism during antiretroviral therapy (Harold Burger – Wadsworth Center NY State Dept of Health, Albany Medical College) 12:00 – 12:15 Prospective associations of HIV-specific CD8+ T cell proliferation and IFN-γ ELISPOT responses with clinical outcome in HIV+ Kenyans (Lyle McKinnon – Univ. Toronto / Univ. Manitoba / Univ. Nairobi) 12:15 – 12:25 PASER monitoring studies in Kenya to establish HIV drug resistance among adults using Highly Active Anti-Retroviral Therapy (HAART) (Millicent Olulo – ICRH / Univ. Ghent / Univ. Nairobi) 12:25 – 12:35 Low-level HIV-1 drug resistance is prevalent in women and children taking antiretrovirals for prophylaxis and treatment in Kenya (Dara Lehman – Univ. Washington / Univ. Nairobi) 12:35 – 12:45 Virologic outcomes and drug resistance mutations among HIV-1 positive pregnant women who received zidovudine, lamivudine and nevirapine for PMTCT (Alex Kasembeli (CDC / KEMRI) 12:45 – 1:00 Long peptides induce polyfunctional macaque T cells against conserved regions of HIV1 with superior breadth to single-gene vaccines (Tomas Hanke – Oxford Univ) 1:00 – 2:00 lunch Session XII: Treatment and Care II Co-Chairs: Christina Mwachari Rupert Kaul 2:00 – 2:15 Preliminary findings from Kenya’s pilot study on early warning indicators for HIV drug resistance (Sarah Masyuko – NASCOP / CDC / KEMRI) 2:15 – 2:25 Evaluation of nucleic acid testing on dried blood spots for HIV screening of blood bank units in Kenya (Julie Okonji – CDC / KEMRI) 2:25 – 2:35 Evaluation of HIV-1 viral load measurement from dried blood spots versus plasma samples in Kenya (Kenneth Ndiege – CDC / KEMRI) 2:35 – 2:50 Evaluation of a real-time in-house methodology for Mycobacterium tuberculosis detection from patient samples (Meenu Sharma – Canadian National Reference Centre for Mycobacteriology / Univ. Manitoba) 2:50 - 3:00 QASI – an international quality assurance program for CD4 enumeration (Blake Ball – Univ. Manitoba / Univ. Nairobi) 3:00 – 3:10 WHO stage 4 conditions in an HIV-positive cohort in Western Kenya (Patrick Oyaro – FACES / KEMRI / UCSF) 3:10 – 3:20 Case fatality due to cryptococcal meningitis in a retrospective cohort in Kenya (C. Kendi - FACES / KEMRI / UCSF) 3:20 – 3:30 Factors associated with quality of life (QoL) in HIV treatment and care clinics in Western Kenya (Arbogast Oyanga – FACES / UCSF / KEMRI) 3:30 – 3:40 Integration of HIV care with primary health care services: impact on patient knowledge, satisfaction and stigma in Suba District (Patrick Mbullo – FACES / KEMRI / UCSF) 3:40 – 4:00 Coffee / tea 4:00 – 5:30 SATELLITE MEETING –ICT TECHNOLOGIES FOR HIV SCREENING, CARE AND PREVENTION (Conveners – Ann Kurth, Tony Kariri) 4:00 – 5:30 SATELLITE MEETING – ICRH BRIEFING – ACTIVITIES AND PROGRAMMES – PAST, PRESENT AND FUTURE (Convener – Fiona Mbai) Friday, January 29, 2010 Session XIII: Interventions IV Co-Chairs: Elizabeth Ngugi Lisa Mills 8:30 – 8:45 Baseline survey of hospitals preparedness to provide medical and psychosocial care for gender-based violence survivors in sampled sites in Kenya (Jane Wakahe – GTZ / Univ. Nairobi) 8:45 – 9:00 Gender-Based Violence and Recovery Centre, Coast Provincial General Hospital – providing comprehensive care (Christine Katingima – UCSF / ICRH / Univ. Ghent / Univ. Nairobi) 9:00 – 9:15 Interactive group counseling can change harmful intravaginal practices among female sex workers (F. Kashonga – Univ. Washington / Univ. Nairobi) 9:15 – 9:30 Scaling up “Families Matter!”: supporting organisations in Kenya to deliver and sustain a parent-based intervention to prevent HIV in pre-teens (Juliet Ochura – Inst of TropMed / KEMRI 9:30 – 9:45 Disclosing HIV test results: experiences of HIV-discordant couples in Thika and Nairobi Districts (Kenneth Ngure – Univ. Washington / Univ. Nairobi) 9:45 – 10:00 Introduction to the CPGH-ICRH Clinical Laboratory (Sammy Wambua - – ICRH / Univ. Ghent / Univ. Nairobi) 10:00 – 10:15 Community-researcher partnership creation to improve clinical research outcomes (Jacqueline Naulikha – Univ. Washington / Univ. Nairobi). 10:15 – 10:30 Overcoming structural challenges to ensure high retention in clinical trials: experiences among HIV-discordant couples enrolled in an HIV prevention study in Kenya (Josephine Odoyo – UCSF / KEMRI) 10:30 – 11:00 coffee / tea Session XIV: Family Planning and Reproductive Health Co-Chairs: Joshua Kimani Marleen Temmerman 11:00 – 11:15 Service delivery characteristics associated with contraceptive use among youth clients in voluntary counselling and testing clinics with integrated family planning services (Rose Otieno-Masaba – FHI) 11:15 – 11:30 Integrating RH/FP with HIV services – the USAID APHIA2 Rift Valley and Coast Experience (Solomon Marsden – FHI) 11:30 – 11:45 Adaptation of a sexual and reproductive health intervention for adolescents living with HIV (ALWH): from Healthy Choices for a better and brighter future (Gillian Njika – Inst. TropMed / KEMRI) 11:45 – 12:00 Sexual and reproductive health needs of adolescents living with HIV in Western Kenya; findings from focus group discussions with ALWH (Brenda Amimo – Inst. TropMed / KEMRI) 12:00 – 12:15 Sexual and reproductive health needs of adolescents living with HIV in Western Kenya; perspectives of caregivers and health service providers (Daniel Adipo – Inst. TropMed / KEMRI) 12:15 – 12:30 Attitudes towards family planning among HIV-positive pregnant mothers enrolled in a prevention of mother-to-child transmission (PMTCT) study and among their partners in Kisumu (Kevin Achola – CDC / KEMRI) 12:30 -12:45 Selecting a suitable population for a vaginal microbicide safety and acceptability trial in Kisumu: a comparison of two communities (Serah Gitome – Univ. Washington / UCSF / KEMRI) 12:45 – 1:00 Designing the next generation microbicide leads: Lessons Learned from Phase III trials (Isaac Malonza – Jhpiego) 1:00 – 2:00 Lunch Session XV: Epidemiology, Transmission, Risk Factors II Co-Chairs: Fiona Mbai Scott McClelland 2:00 – 2:15 Poverty and a lack of empowerment are a hindrance to Prevention with Positive (PwP) strategies among HIV positive women (Maureen Akolo – Univ. Manitoba / Univ. Nairobi) 2:15 – 2:30 Health-care seeking prior to HIV seroconversion in Coastal Kenya (Mary Mwangome – Wellcome Trust / KEMRI) 2:30 – 2:45 Vaginal flora and the risk of HIV-1 acquisition in women: concept and study design for a recently-funded research proposal (Vernon Mochache – Univ. Washington / Univ. Nairobi) 2:45 – 3:00 Treatment with antiretroviral therapy is not associated with increased sexual risk behaviour in Kenyan female sex workers (George Wanje - Univ. Washington / Univ. Nairobi) 3:00 – 3:15 Effect of cervical infections and their treatment on cervical HIV-1 shedding in women taking antiretroviral therapy: a prospective study (Ruth Gitau - Univ. Washington / Univ. Nairobi) 3:15 – 3:30 From local to universal – expanding the concept and practice of health and human rights among Muslim women in Mombasa (Marleen Renders – Human Rights Centre, Ghent University Law School / ICRH / Univ. Nairobi) 3:30 – 4:00 SUMMING UP and CLOSING CEREMONIES Summing up – Benson Estambale, Omu Anzala, Marleen Temmerman Greetings from the University of Ghent - Prof Paul Van Cauwenberge, Rector, Univ. Ghent Closing remarks – Prof. Z. Ngumi, Dean, School of Medicine, Univ. Nairobi (to be confirmed) -